Experiment set5IT002 for Klebsiella michiganensis M5al

Compare to:

Trisodium citrate dihydrate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.2 -6.3 histidinol-phosphate transaminase compare
BWI76_RS20965 -8.9 -6.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00805 -7.6 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS05840 -7.0 -4.8 glutamate 5-kinase compare
BWI76_RS18935 -6.8 -7.9 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00990 -6.5 -7.8 ketol-acid reductoisomerase compare
BWI76_RS23920 -6.5 -4.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS02815 -6.4 -4.4 fructose-bisphosphatase class I compare
BWI76_RS05835 -6.3 -4.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS18940 -6.3 -7.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04470 -6.3 -9.6 carbamoyl phosphate synthase large subunit compare
BWI76_RS04675 -6.2 -6.7 3-isopropylmalate dehydrogenase compare
BWI76_RS11850 -6.1 -11.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS18925 -6.0 -8.5 histidinol dehydrogenase compare
BWI76_RS22755 -6.0 -9.2 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04665 -6.0 -20.8 3-isopropylmalate dehydratase small subunit compare
BWI76_RS21475 -5.9 -6.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00855 -5.9 -8.0 argininosuccinate lyase compare
BWI76_RS04250 -5.8 -8.8 homoserine kinase compare
BWI76_RS18920 -5.8 -5.6 ATP phosphoribosyltransferase compare
BWI76_RS01210 -5.7 -3.5 tyrosine recombinase XerC compare
BWI76_RS04685 -5.7 -12.1 putative leucine operon leader peptide compare
BWI76_RS20895 -5.7 -6.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11840 -5.6 -3.0 tryptophan synthase subunit alpha compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS04255 -5.5 -10.6 threonine synthase compare
BWI76_RS04670 -5.5 -9.2 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01655 -5.5 -8.8 homoserine O-succinyltransferase compare
BWI76_RS24285 -5.4 -9.0 cystathionine beta-lyase compare
BWI76_RS04160 -5.4 -5.9 phosphoserine phosphatase compare
BWI76_RS00785 -5.3 -5.1 cystathionine gamma-synthase compare
BWI76_RS09755 -5.2 -7.3 phosphoserine transaminase compare
BWI76_RS09760 -5.2 -4.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20355 -5.1 -3.7 colicin V production protein compare
BWI76_RS11855 -5.1 -8.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS07070 -5.1 -6.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04465 -5.1 -6.0 carbamoyl-phosphate synthase small subunit compare
BWI76_RS22690 -5.1 -4.9 adenylyl-sulfate kinase compare
BWI76_RS18955 -5.0 -7.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21265 -5.0 -15.4 phosphoribosylformylglycinamidine synthase compare
BWI76_RS10990 -4.9 -4.8 dihydroorotase compare
BWI76_RS04680 -4.9 -12.6 2-isopropylmalate synthase compare
BWI76_RS08395 -4.9 -2.9 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS11860 -4.8 -11.6 anthranilate synthase component I compare
BWI76_RS01615 -4.7 -12.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS08430 -4.6 -8.7 succinate--CoA ligase subunit alpha compare
BWI76_RS25115 -4.5 -8.1 argininosuccinate synthase compare
BWI76_RS00985 -4.5 -7.5 transcriptional regulator IlvY compare
BWI76_RS23365 -4.5 -5.0 LysR family transcriptional regulator compare
BWI76_RS23360 -4.5 -3.5 diaminopimelate decarboxylase compare
BWI76_RS20350 -4.5 -6.3 amidophosphoribosyltransferase compare
BWI76_RS02995 -4.5 -9.0 aspartate carbamoyltransferase compare
BWI76_RS11965 -4.5 -6.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS08405 -4.4 -5.2 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS23830 -4.4 -6.9 hypothetical protein compare
BWI76_RS27390 -4.4 -4.8 ribonuclease PH compare
BWI76_RS04645 -4.4 -5.5 3-dehydroquinase compare
BWI76_RS07065 -4.4 -6.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09910 -4.4 -16.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11845 -4.4 -2.8 tryptophan synthase subunit beta compare
BWI76_RS00980 -4.3 -11.6 PLP-dependent threonine dehydratase compare
BWI76_RS27385 -4.3 -7.1 orotate phosphoribosyltransferase compare
BWI76_RS00975 -4.3 -7.3 dihydroxy-acid dehydratase compare
BWI76_RS03010 -4.3 -6.2 ornithine carbamoyltransferase compare
BWI76_RS22760 -4.1 -8.3 sulfite reductase subunit beta compare
BWI76_RS08425 -4.1 -7.1 succinyl-CoA ligase subunit beta compare
BWI76_RS00845 -4.0 -8.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS18950 -4.0 -6.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21465 -4.0 -4.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04245 -3.9 -15.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS20435 -3.9 -2.3 chorismate synthase compare
BWI76_RS22765 -3.8 -16.4 sulfite reductase subunit alpha compare
BWI76_RS02735 -3.8 -6.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS26570 -3.8 -4.4 anion permease compare
BWI76_RS02530 -3.7 -3.6 tRNA dimethylallyltransferase compare
BWI76_RS08390 -3.6 -5.7 hypothetical protein compare
BWI76_RS04240 -3.6 -3.1 thr operon leader peptide compare
BWI76_RS20640 -3.5 -7.0 cysteine synthase A compare
BWI76_RS00400 -3.4 -2.3 glutamine synthetase compare
BWI76_RS09660 -3.3 -3.2 DNA translocase FtsK compare
BWI76_RS08520 -3.3 -2.7 colicin transporter TolQ compare
BWI76_RS23240 -3.2 -3.8 exonuclease V subunit gamma compare
BWI76_RS00850 -3.2 -8.4 acetylglutamate kinase compare
BWI76_RS01610 -3.0 -4.2 phosphoribosylamine--glycine ligase compare
BWI76_RS23220 -2.9 -5.0 amino-acid N-acetyltransferase compare
BWI76_RS01200 -2.9 -2.8 diaminopimelate epimerase compare
BWI76_RS01185 -2.8 -3.3 adenylate cyclase compare
BWI76_RS04705 -2.7 -6.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS17720 -2.6 -2.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS09645 -2.6 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS20970 -2.6 -2.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS15825 -2.6 -2.2 hypothetical protein compare
BWI76_RS16275 -2.4 -3.7 fumarate hydratase FumA compare
BWI76_RS26055 -2.4 -5.9 siroheme synthase compare
BWI76_RS21140 -2.4 -4.1 molecular chaperone HscA compare
BWI76_RS05015 -2.4 -3.1 transcriptional regulator compare
BWI76_RS26455 -2.3 -4.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS05200 -2.2 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00965 -2.1 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS23480 -2.1 -11.5 EAL domain-containing protein compare
BWI76_RS25355 -2.1 -6.8 cell division protein ZapE compare
BWI76_RS20440 -2.0 -2.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS26460 -2.0 -4.6 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS01070 -2.0 -6.8 thiol reductase thioredoxin compare
BWI76_RS04530 -2.0 -2.6 peptidylprolyl isomerase SurA compare
BWI76_RS09190 -2.0 -5.3 hypothetical protein compare
BWI76_RS23230 -2.0 -3.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS25320 -1.9 -9.0 glutamate synthase compare
BWI76_RS18605 -1.9 -1.8 oxidoreductase molybdopterin-binding protein compare
BWI76_RS06185 -1.8 -7.2 shikimate kinase II compare
BWI76_RS24900 -1.8 -2.5 DeoR family transcriptional regulator compare
BWI76_RS25645 -1.7 -7.6 shikimate dehydrogenase compare
BWI76_RS22695 -1.7 -4.9 sulfate adenylyltransferase compare
BWI76_RS09640 -1.7 -6.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS04555 -1.7 -10.7 citrate/acetate antiporter conserved
BWI76_RS18165 -1.6 -2.5 NUDIX pyrophosphatase compare
BWI76_RS20650 -1.6 -2.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS12090 -1.5 -1.2 HNH endonuclease compare
BWI76_RS04550 -1.5 -8.2 two-component sensor kinase compare
BWI76_RS24945 -1.5 -1.3 glutamine amidotransferase compare
BWI76_RS17065 -1.5 -6.0 phosphoenolpyruvate synthase compare
BWI76_RS04545 -1.5 -7.0 two-component response regulator for citrate compare
BWI76_RS01205 -1.5 -2.2 DUF484 family protein compare
BWI76_RS25925 -1.5 -4.8 hypothetical protein compare
BWI76_RS11520 -1.5 -1.3 hypothetical protein compare
BWI76_RS20910 -1.5 -4.9 glycine cleavage system transcriptional repressor compare
BWI76_RS25315 -1.5 -7.7 glutamate synthase large subunit compare
BWI76_RS23030 -1.4 -2.8 cobalamin biosynthesis protein CbiM compare
BWI76_RS01800 -1.4 -2.8 glucose-6-phosphate isomerase compare
BWI76_RS27820 -1.4 -1.6 ilvB operon leader peptide IvbL compare
BWI76_RS21580 -1.4 -1.9 SsrA-binding protein compare
BWI76_RS00390 -1.3 -3.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS19600 -1.3 -3.8 hypothetical protein compare
BWI76_RS25420 -1.3 -4.3 malate dehydrogenase compare
BWI76_RS16955 -1.3 -1.8 hypothetical protein compare
BWI76_RS00180 -1.3 -1.1 F0F1 ATP synthase subunit epsilon compare
BWI76_RS02985 -1.3 -4.0 reactive intermediate/imine deaminase compare
BWI76_RS03080 -1.3 -2.7 (Fe-S)-cluster assembly protein compare
BWI76_RS00960 -1.3 -5.9 acetolactate synthase 2 catalytic subunit compare
BWI76_RS02610 -1.3 -4.6 transcriptional regulator compare
BWI76_RS27430 -1.3 -1.3 (p)ppGpp synthetase compare
BWI76_RS01885 -1.3 -1.5 CsbD family protein compare
BWI76_RS00345 -1.2 -2.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS27815 -1.2 -7.1 acetolactate synthase catalytic subunit compare
BWI76_RS17290 -1.2 -2.3 formyltetrahydrofolate deformylase compare
BWI76_RS05260 -1.2 -1.7 chaperone compare
BWI76_RS16895 -1.2 -1.8 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS24385 -1.2 -5.7 phosphodiesterase compare
BWI76_RS22805 -1.2 -5.8 GTP diphosphokinase compare
BWI76_RS13435 -1.2 -2.0 hypothetical protein compare
BWI76_RS23020 -1.2 -1.7 cobalamin biosynthesis protein CbiQ compare
BWI76_RS18755 -1.2 -1.3 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS25065 -1.2 -2.7 polyribonucleotide nucleotidyltransferase compare
BWI76_RS21450 -1.1 -2.1 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS06295 -1.1 -3.3 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS21070 -1.1 -2.0 outer membrane protein assembly factor BamB compare
BWI76_RS08530 -1.1 -2.5 protein TolA compare
BWI76_RS21370 -1.1 -1.7 ATP-dependent RNA helicase SrmB compare
BWI76_RS09870 -1.1 -6.4 aromatic amino acid aminotransferase compare
BWI76_RS27440 -1.1 -2.5 DNA helicase RecG compare
BWI76_RS15810 -1.1 -4.2 hypothetical protein compare
BWI76_RS26075 -1.1 -2.2 DNA adenine methylase compare
BWI76_RS00140 -1.1 -1.1 phosphate transport system regulator PhoU compare
BWI76_RS03880 -1.1 -3.1 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS26620 -1.1 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS16965 -1.1 -1.7 murein lipoprotein compare
BWI76_RS09195 -1.0 -1.3 N-acetyltransferase compare
BWI76_RS15715 -1.0 -2.7 putative ninG protein compare
BWI76_RS26000 -1.0 -4.2 aspartate aminotransferase family protein compare
BWI76_RS12305 -1.0 -4.4 hypothetical protein compare
BWI76_RS25060 -1.0 -1.4 lipoprotein NlpI compare
BWI76_RS17975 -1.0 -2.5 tail-specific protease compare
BWI76_RS21000 -1.0 -3.9 exopolyphosphatase compare
BWI76_RS15830 -1.0 -1.8 hypothetical protein compare
BWI76_RS03040 -1.0 -1.5 leucyl aminopeptidase compare
BWI76_RS05680 -1.0 -3.2 LacI family transcriptional regulator compare
BWI76_RS13595 -1.0 -3.2 transcriptional regulator compare
BWI76_RS01170 -1.0 -2.2 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS11040 -0.9 -2.2 ribonuclease E compare
BWI76_RS15840 -0.9 -2.1 prophage protein compare
BWI76_RS09255 -0.9 -1.3 hypothetical protein compare
BWI76_RS09390 -0.9 -2.5 phage tail protein compare
BWI76_RS25225 -0.9 -2.8 ABC transporter permease compare
BWI76_RS02180 -0.9 -1.1 hypothetical protein compare
BWI76_RS06730 -0.9 -2.2 lac repressor compare
BWI76_RS08535 -0.9 -1.2 translocation protein TolB compare
BWI76_RS19605 -0.9 -2.7 CidB/LrgB family autolysis modulator compare
BWI76_RS20695 -0.9 -2.0 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS23265 -0.9 -2.7 hypothetical protein compare
BWI76_RS19685 -0.9 -3.6 lysine transporter compare
BWI76_RS21480 -0.9 -2.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS17615 -0.9 -3.0 RNA pseudouridine synthase compare
BWI76_RS10640 -0.9 -2.6 AraC family transcriptional regulator compare
BWI76_RS19870 -0.9 -2.1 malate:quinone oxidoreductase compare
BWI76_RS13965 -0.9 -2.1 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS21100 -0.8 -2.5 nucleoside-diphosphate kinase compare
BWI76_RS16315 -0.8 -1.5 SirA-like protein compare
BWI76_RS20810 -0.8 -3.2 ethanolamine utilization cobalamin adenosyltransferase compare
BWI76_RS21690 -0.8 -1.5 hypothetical protein compare
BWI76_RS01060 -0.8 -3.2 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Trisodium citrate dihydrate in Klebsiella michiganensis M5al

For carbon source Trisodium citrate dihydrate across organisms