Experiment set5H6 for Pseudomonas stutzeri RCH2

Compare to:

LB with methylglyoxal 0.0016 vol%

200 most important genes:

  gene name fitness t score description  
Psest_2034 -6.4 -10.8 ATPase related to the helicase subunit of the Holliday junction resolvase conserved
Psest_2071 -6.4 -12.2 hydroxyacylglutathione hydrolase conserved
Psest_3120 -5.8 -8.0 lactoylglutathione lyase conserved
Psest_3317 -5.1 -6.1 Phosphotransferase System HPr (HPr) Family compare
Psest_1496 -5.1 -2.5 Holliday junction DNA helicase, RuvA subunit compare
Psest_1999 -4.8 -2.3 pseudouridine synthase compare
Psest_3031 -4.7 -1.3 hypothetical protein compare
Psest_3395 -4.2 -1.7 hypothetical protein compare
Psest_3306 -4.2 -6.4 conserved hypothetical integral membrane protein compare
Psest_0691 -4.2 -19.4 ribonuclease R compare
Psest_2232 -4.1 -17.4 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_2945 -4.1 -3.4 septum site-determining protein MinC compare
Psest_1242 -4.0 -3.8 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_0259 -3.9 -1.5 cell division ATP-binding protein FtsE compare
Psest_3304 -3.8 -6.7 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3305 -3.7 -11.5 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_1510 -3.5 -7.0 Putative Zn-dependent protease, contains TPR repeats compare
Psest_2285 -3.4 -7.6 ATP-dependent protease La compare
Psest_0062 -3.4 -6.9 tryptophan synthase, alpha subunit compare
Psest_3647 -3.4 -7.5 Indole-3-glycerol phosphate synthase compare
Psest_2712 -3.4 -6.6 Surface lipoprotein compare
Psest_3883 -3.4 -5.6 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3307 -3.3 -10.4 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3303 -3.3 -8.6 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0498 -3.3 -1.6 ribosome small subunit-dependent GTPase A compare
Psest_2316 -3.2 -10.9 phosphoenolpyruvate synthase compare
Psest_3391 -3.2 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_3129 -3.2 -2.2 tyrosine recombinase XerD compare
Psest_0737 -3.0 -0.8 Cu(I)-responsive transcriptional regulator compare
Psest_1058 -3.0 -2.2 ribosomal-protein-alanine acetyltransferase compare
Psest_3732 -3.0 -8.7 polyphosphate kinase 1 compare
Psest_2981 -3.0 -4.2 sodium pump decarboxylases, gamma subunit compare
Psest_1724 -3.0 -3.5 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1804 -3.0 -5.5 Superfamily II DNA and RNA helicases compare
Psest_1631 -2.9 -1.6 Uncharacterized conserved small protein compare
Psest_2018 -2.9 -4.7 Uncharacterized conserved protein compare
Psest_3862 -2.9 -11.1 phosphoenolpyruvate-protein phosphotransferase compare
Psest_2011 -2.8 -7.0 Predicted permease compare
Psest_2123 -2.8 -1.9 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_0063 -2.8 -2.7 tryptophan synthase, beta subunit compare
Psest_0309 -2.7 -1.7 RND family efflux transporter, MFP subunit compare
Psest_0542 -2.7 -4.1 AMP nucleosidase compare
Psest_2946 -2.6 -4.9 septum site-determining protein MinD compare
Psest_1505 -2.6 -3.5 Organic radical activating enzymes compare
Psest_0398 -2.5 -6.0 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain compare
Psest_2243 -2.5 -1.0 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1506 -2.5 -7.0 queuosine biosynthesis protein QueC compare
Psest_2857 -2.5 -8.8 Rad3-related DNA helicases conserved
Psest_2907 -2.4 -1.9 Protein of unknown function (DUF3618). compare
Psest_1567 -2.4 -4.1 Transcriptional regulator compare
Psest_1498 -2.4 -3.4 tol-pal system-associated acyl-CoA thioesterase compare
Psest_3195 -2.3 -8.3 intracellular protease, PfpI family conserved
Psest_3648 -2.3 -7.9 anthranilate phosphoribosyltransferase compare
Psest_2872 -2.3 -1.5 protein RecA compare
Psest_0296 -2.3 -9.4 glutathione synthetase, prokaryotic compare
Psest_2259 -2.2 -10.8 excinuclease ABC, C subunit conserved
Psest_1296 -2.2 -8.7 excinuclease ABC, B subunit conserved
Psest_0708 -2.2 -2.7 outer membrane assembly lipoprotein YfiO compare
Psest_2584 -2.2 -5.4 Phosphoribosylanthranilate isomerase compare
Psest_1663 -2.1 -4.3 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_3576 -2.1 -12.3 excinuclease ABC, A subunit conserved
Psest_4393 -2.1 -6.6 Capsule polysaccharide export protein compare
Psest_1884 -2.1 -2.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3351 -2.0 -6.9 peptide chain release factor 3 compare
Psest_2122 -2.0 -1.1 Parvulin-like peptidyl-prolyl isomerase compare
Psest_1910 -1.9 -2.5 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_2581 -1.9 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_0692 -1.9 -3.3 rRNA methylase, putative, group 3 compare
Psest_1653 -1.8 -11.2 transcription-repair coupling factor (mfd) compare
Psest_4364 -1.8 -4.7 16S rRNA (guanine(527)-N(7))-methyltransferase GidB compare
Psest_0218 -1.8 -3.4 Acyl-CoA hydrolase compare
Psest_1163 -1.8 -3.0 diguanylate cyclase (GGDEF) domain compare
Psest_1765 -1.8 -6.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3578 -1.8 -9.7 Catalase conserved
Psest_0987 -1.8 -2.8 Predicted periplasmic or secreted lipoprotein compare
Psest_0402 -1.8 -1.9 glycosyltransferase, MGT family compare
Psest_1509 -1.8 -6.5 quinolinate synthetase complex, A subunit compare
Psest_1259 -1.8 -4.2 23S rRNA m2A2503 methyltransferase compare
Psest_3998 -1.8 -1.7 glutamate--cysteine ligase compare
Psest_0028 -1.8 -3.3 Coproporphyrinogen III oxidase compare
Psest_1472 -1.7 -4.5 Protein of unknown function (DUF3108). compare
Psest_2714 -1.7 -2.1 7-cyano-7-deazaguanine reductase compare
Psest_3477 -1.7 -2.0 Signal transduction histidine kinase compare
Psest_1627 -1.7 -7.5 Superfamily II DNA and RNA helicases compare
Psest_2590 -1.7 -1.7 3-isopropylmalate dehydratase, small subunit compare
Psest_3902 -1.7 -2.8 hypothetical protein compare
Psest_1920 -1.7 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_3990 -1.7 -5.4 PAP2 superfamily. compare
Psest_2424 -1.7 -1.5 K+ transport systems, NAD-binding component compare
Psest_3536 -1.7 -1.0 hypothetical protein compare
Psest_3092 -1.6 -1.7 ribonuclease III, bacterial compare
Psest_3401 -1.6 -4.0 DNA repair protein RadA compare
Psest_3044 -1.6 -4.6 deoxycytidine triphosphate deaminase compare
Psest_2646 -1.6 -2.4 SOS regulatory protein LexA compare
Psest_2037 -1.6 -4.5 uroporphyrin-III C-methyltransferase compare
Psest_1952 -1.6 -4.0 hypothetical protein compare
Psest_4142 -1.6 -1.2 hypothetical protein compare
Psest_3090 -1.6 -5.4 DNA repair protein RecO compare
Psest_3045 -1.6 -2.7 Cold shock proteins compare
Psest_2517 -1.6 -3.0 hypothetical protein compare
Psest_3123 -1.5 -2.9 dihydroorotase, homodimeric type compare
Psest_3626 -1.5 -4.3 hypothetical protein compare
Psest_0958 -1.5 -7.9 Oligoketide cyclase/lipid transport protein compare
Psest_0609 -1.5 -1.6 hypothetical protein compare
Psest_2104 -1.5 -2.5 IscR-regulated protein YhgI compare
Psest_1871 -1.5 -5.8 Predicted esterase of the alpha-beta hydrolase superfamily compare
Psest_4098 -1.5 -2.7 Superfamily I DNA and RNA helicases compare
Psest_3367 -1.4 -1.2 translation initation factor SUI1, putative, prokaryotic compare
Psest_2384 -1.4 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_3881 -1.4 -0.8 hypothetical protein compare
Psest_1562 -1.4 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_1622 -1.4 -3.1 hypothetical protein compare
Psest_3118 -1.4 -4.6 endonuclease III compare
Psest_3497 -1.4 -3.2 Predicted metalloprotease compare
Psest_0401 -1.4 -0.6 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_0442 -1.4 -5.0 ATPases of the AAA+ class compare
Psest_4010 -1.4 -1.3 peroxiredoxin, OsmC subfamily compare
Psest_0277 -1.4 -1.2 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_0716 -1.3 -1.5 Protein of unknown function (DUF3094). compare
Psest_3767 -1.3 -0.9 tyrosine recombinase XerC compare
Psest_0368 -1.3 -0.8 Transcriptional regulator compare
Psest_1227 -1.3 -1.8 Predicted SAM-dependent methyltransferase compare
Psest_4220 -1.3 -1.4 Protein of unknown function (DUF2782). compare
Psest_1031 -1.3 -5.6 Uncharacterized protein conserved in bacteria compare
Psest_0558 -1.3 -0.5 urease, beta subunit compare
Psest_3389 -1.3 -2.4 hypothetical protein compare
Psest_0449 -1.3 -6.3 Glutamine synthetase adenylyltransferase compare
Psest_1525 -1.3 -4.7 Uncharacterized protein conserved in bacteria compare
Psest_3173 -1.3 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_0119 -1.3 -1.5 hypothetical protein compare
Psest_0426 -1.3 -2.1 Transposase and inactivated derivatives compare
Psest_2810 -1.3 -4.1 5'/3'-nucleotidase SurE compare
Psest_1016 -1.3 -2.5 putative TIM-barrel protein, nifR3 family compare
Psest_0568 -1.3 -1.9 pseudouridine synthase compare
Psest_1122 -1.2 -8.6 putative adhesin (DUF1302) (from data) compare
Psest_0181 -1.2 -3.0 glycine cleavage system T protein compare
Psest_1453 -1.2 -4.6 Glycerol-3-phosphate dehydrogenase compare
Psest_2067 -1.2 -1.1 ABC-type oligopeptide transport system, periplasmic component compare
Psest_2634 -1.2 -2.7 glycine betaine aldehyde dehydrogenase compare
Psest_4078 -1.2 -1.8 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_3973 -1.2 -0.9 Anti-sigma regulatory factor (Ser/Thr protein kinase) compare
Psest_0316 -1.2 -1.4 Cytochrome c556 compare
Psest_1947 -1.2 -3.0 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2359 -1.2 -2.1 Predicted permeases compare
Psest_1643 -1.2 -1.0 hypothetical protein compare
Psest_3784 -1.2 -1.3 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_3810 -1.2 -1.9 orotate phosphoribosyltransferase compare
Psest_0998 -1.2 -2.3 poly(A) polymerase compare
Psest_3177 -1.2 -1.8 hypothetical protein compare
Psest_0520 -1.2 -0.7 hypothetical protein compare
Psest_1241 -1.2 -3.3 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_0515 -1.1 -3.2 rare lipoprotein A compare
Psest_4191 -1.1 -1.3 Transcriptional regulator compare
Psest_4043 -1.1 -1.9 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_0969 -1.1 -1.4 transcription elongation factor GreA compare
Psest_0378 -1.1 -1.0 Lactate dehydrogenase and related dehydrogenases compare
Psest_4042 -1.1 -2.4 hypothetical protein compare
Psest_0779 -1.1 -1.6 tyrosine aminotransferase (EC 2.6.1.57) (from data) compare
Psest_3235 -1.1 -7.3 Protein of unknown function (DUF1329). compare
Psest_1783 -1.1 -1.5 Predicted transporter component compare
Psest_3700 -1.1 -0.3 hypothetical protein compare
Psest_0510 -1.1 -2.0 iojap-like ribosome-associated protein compare
Psest_2585 -1.1 -0.7 pseudouridylate synthase I compare
Psest_0677 -1.1 -3.6 iron-sulfur cluster binding protein, putative compare
Psest_1750 -1.1 -2.1 Protein of unknown function (DUF2802). compare
Psest_2670 -1.1 -1.5 Uncharacterized conserved protein compare
Psest_0891 -1.1 -3.8 Uncharacterized protein conserved in bacteria compare
Psest_1817 -1.1 -3.1 hypothetical protein compare
Psest_3926 -1.1 -5.9 GTP-binding protein TypA/BipA compare
Psest_2899 -1.1 -1.4 hypothetical protein compare
Psest_0165 -1.1 -1.8 protein-export chaperone SecB compare
Psest_2726 -1.1 -1.0 Rhodanese-related sulfurtransferase compare
Psest_2411 -1.1 -3.8 PAS domain S-box compare
Psest_1419 -1.1 -2.7 Transcriptional regulator compare
Psest_2128 -1.1 -2.5 Acyl-CoA dehydrogenases compare
Psest_2260 -1.1 -7.3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0993 -1.1 -7.1 Glucose-6-phosphate isomerase compare
Psest_0325 -1.1 -5.5 Putative threonine efflux protein compare
Psest_3140 -1.1 -3.0 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Psest_1098 -1.0 -5.3 Restriction endonuclease S subunits compare
Psest_0650 -1.0 -2.2 RNA polymerase sigma factor, sigma-70 family compare
Psest_1398 -1.0 -2.9 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component compare
Psest_1913 -1.0 -1.8 Transcriptional regulator compare
Psest_0697 -1.0 -2.5 ribosomal protein L9 compare
Psest_0675 -1.0 -2.5 Predicted periplasmic lipoprotein compare
Psest_1516 -1.0 -1.4 Uncharacterized lipoprotein compare
Psest_1117 -1.0 -3.3 Lipid A 3-O-deacylase (PagL). compare
Psest_1052 -1.0 -1.6 Uncharacterized protein involved in chromosome partitioning compare
Psest_0187 -1.0 -1.6 Metal-dependent hydrolase compare
Psest_1725 -1.0 -6.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1818 -1.0 -5.6 GDP-mannose 4,6-dehydratase compare
Psest_1414 -1.0 -3.8 Lactoylglutathione lyase and related lyases compare
Psest_1134 -1.0 -2.2 alkyl hydroperoxide reductase, F subunit compare
Psest_4274 -1.0 -2.1 hypothetical protein compare
Psest_1574 -1.0 -1.4 phenazine biosynthesis protein PhzF family compare
Psest_3128 -1.0 -3.3 Protein-disulfide isomerase compare
Psest_0457 -1.0 -2.4 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1339 -1.0 -4.9 ATP-dependent helicase HrpA compare
Psest_2621 -1.0 -2.0 TadE-like protein. compare
Psest_3827 -1.0 -1.9 Transcriptional regulator compare


Specific Phenotypes

For 18 genes in this experiment

For stress methylglyoxal in Pseudomonas stutzeri RCH2

For stress methylglyoxal across organisms