Experiment set5H30 for Shewanella amazonensis SB2B

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Anaerobic growth with fumarate as electron acceptor

Group: anaerobic
Media: ShewMM + Sodium Fumarate dibasic (20 mM)
Culturing: SB2B_ML5, hungate, Anaerobic, at 37 (C), shaken=orbital
Growth: about 3.2 generations
By: Kelly on 8/28/2013
Media components: 1.5 g/L Ammonium chloride, 1.75 g/L Sodium Chloride, 0.61 g/L Magnesium chloride hexahydrate, 0.1 g/L Potassium Chloride, 0.6 g/L Sodium phosphate monobasic monohydrate, 20 mM Sodium D,L-Lactate, 30 mM PIPES sesquisodium salt, Wolfe's mineral mix (0.03 g/L Magnesium Sulfate Heptahydrate, 0.015 g/L Nitrilotriacetic acid, 0.01 g/L Sodium Chloride, 0.005 g/L Manganese (II) sulfate monohydrate, 0.001 g/L Cobalt chloride hexahydrate, 0.001 g/L Zinc sulfate heptahydrate, 0.001 g/L Calcium chloride dihydrate, 0.001 g/L Iron (II) sulfate heptahydrate, 0.00025 g/L Nickel (II) chloride hexahydrate, 0.0002 g/L Aluminum potassium sulfate dodecahydrate, 0.0001 g/L Copper (II) sulfate pentahydrate, 0.0001 g/L Boric Acid, 0.0001 g/L Sodium Molybdate Dihydrate, 0.003 mg/L Sodium selenite pentahydrate), Wolfe's vitamin mix (0.1 mg/L Pyridoxine HCl, 0.05 mg/L 4-Aminobenzoic acid, 0.05 mg/L Lipoic acid, 0.05 mg/L Nicotinic Acid, 0.05 mg/L Riboflavin, 0.05 mg/L Thiamine HCl, 0.05 mg/L calcium pantothenate, 0.02 mg/L biotin, 0.02 mg/L Folic Acid, 0.001 mg/L Cyanocobalamin)

Specific Phenotypes

For 58 genes in this experiment

For anaerobic Sodium Fumarate dibasic in Shewanella amazonensis SB2B

For anaerobic Sodium Fumarate dibasic across organisms

SEED Subsystems

Subsystem #Specific
Menaquinone and Phylloquinone Biosynthesis 4
Nitrate and nitrite ammonification 3
Cobalt-zinc-cadmium resistance 2
Molybdenum cofactor biosynthesis 2
Na+ translocating decarboxylases and related biotin-dependent enzymes 2
Pyruvate metabolism I: anaplerotic reactions, PEP 2
Ribonucleotide reduction 2
Ribosome biogenesis bacterial 2
Succinate dehydrogenase 2
Arginine Biosynthesis extended 1
Bacterial RNA-metabolizing Zn-dependent hydrolases 1
Bacterial hemoglobins 1
Biogenesis of c-type cytochromes 1
Butanol Biosynthesis 1
Calvin-Benson cycle 1
Conserved gene cluster associated with Met-tRNA formyltransferase 1
DNA Repair Base Excision 1
DNA repair, UvrABC system 1
Experimental tye 1
Fermentations: Mixed acid 1
Heme and Siroheme Biosynthesis 1
Lactose and Galactose Uptake and Utilization 1
One-carbon metabolism by tetrahydropterines 1
Peptidyl-prolyl cis-trans isomerase 1
Periplasmic disulfide interchange 1
Potassium homeostasis 1
Purine Utilization 1
Purine conversions 1
Serine-glyoxylate cycle 1
Soluble cytochromes and functionally related electron carriers 1
TCA Cycle 1
ZZ gjo need homes 1
cAMP signaling in bacteria 1

Metabolic Maps

Color code by fitness: see overview map or list of maps.

Maps containing gene(s) with specific phenotypes:

MetaCyc Pathways

Pathways that contain genes with specific phenotypes:

Pathway #Steps #Present #Specific
bis(guanylyl molybdenum cofactor) biosynthesis 2 2 2
guanylyl molybdenum cofactor biosynthesis 1 1 1
bis(guanylyl tungstenpterin) cofactor biosynthesis 1 1 1
adenosine nucleotides degradation III 1 1 1
2-carboxy-1,4-naphthoquinol biosynthesis 7 7 6
superpathway of demethylmenaquinol-8 biosynthesis I 9 9 6
superpathway of demethylmenaquinol-9 biosynthesis 9 8 6
superpathway of demethylmenaquinol-6 biosynthesis I 9 8 6
superpathway of menaquinol-8 biosynthesis I 10 10 6
superpathway of menaquinol-12 biosynthesis 10 9 6
superpathway of menaquinol-10 biosynthesis 10 9 6
superpathway of menaquinol-6 biosynthesis 10 9 6
superpathway of menaquinol-13 biosynthesis 10 9 6
superpathway of menaquinol-7 biosynthesis 10 9 6
superpathway of menaquinol-9 biosynthesis 10 9 6
superpathway of menaquinol-11 biosynthesis 10 9 6
adenine and adenosine salvage I 2 2 1
guanine and guanosine salvage I 2 2 1
hydrogen to fumarate electron transfer 2 2 1
glycerol-3-phosphate to fumarate electron transfer 2 2 1
nitrate reduction IV (dissimilatory) 2 2 1
guanine and guanosine salvage II 2 1 1
succinate to cytochrome aa3 oxidase electron transfer 2 1 1
adenine and adenosine salvage II 2 1 1
NADH to fumarate electron transfer 2 1 1
salicylate biosynthesis I 2 1 1
reductive monocarboxylic acid cycle 2 1 1
superpathway of phylloquinol biosynthesis 15 8 6
pyruvate fermentation to acetate IV 3 3 1
pyruvate fermentation to ethanol I 3 3 1
superpathway of guanine and guanosine salvage 3 3 1
D-galactose detoxification 3 2 1
salicylate biosynthesis II 3 2 1
adenine salvage 3 2 1
2,3-dihydroxybenzoate biosynthesis 3 2 1
formate to nitrite electron transfer 3 1 1
pyrimidine deoxyribonucleotides de novo biosynthesis II 7 7 2
formaldehyde oxidation VII (THF pathway) 4 4 1
adenosine deoxyribonucleotides de novo biosynthesis II 4 4 1
guanosine deoxyribonucleotides de novo biosynthesis II 4 4 1
heme b biosynthesis I (aerobic) 4 4 1
(S)-lactate fermentation to propanoate, acetate and hydrogen 13 7 3
L-ornithine biosynthesis I 5 5 1
D-galactose degradation I (Leloir pathway) 5 4 1
L-threonine degradation I 6 6 1
molybdopterin biosynthesis 6 5 1
methylgallate degradation 6 2 1
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) 14 14 2
superpathway of adenosine nucleotides de novo biosynthesis II 7 7 1
superpathway of purine nucleotide salvage 14 13 2
toxoflavin biosynthesis 7 4 1
incomplete reductive TCA cycle 7 4 1
stachyose degradation 7 3 1
pyruvate fermentation to propanoate I 7 3 1
glyphosate degradation III 7 2 1
superpathway of guanosine nucleotides de novo biosynthesis II 8 8 1
mixed acid fermentation 16 15 2
superpathway of heme b biosynthesis from glycine 8 7 1
protocatechuate degradation I (meta-cleavage pathway) 8 3 1
(aminomethyl)phosphonate degradation 8 2 1
flavin biosynthesis I (bacteria and plants) 9 9 1
L-arginine biosynthesis I (via L-ornithine) 9 9 1
flavin biosynthesis III (fungi) 9 8 1
L-arginine biosynthesis III (via N-acetyl-L-citrulline) 9 8 1
superpathway of fermentation (Chlamydomonas reinhardtii) 9 7 1
TCA cycle VI (Helicobacter) 9 7 1
3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent) 9 3 1
3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) 9 3 1
vibriobactin biosynthesis 9 2 1
superpathway of chorismate metabolism 59 50 6
superpathway of heme b biosynthesis from glutamate 10 10 1
Rubisco shunt 10 9 1
flavin biosynthesis II (archaea) 10 6 1
peptidoglycan recycling II 10 5 1
NiFe(CO)(CN)2 cofactor biosynthesis 10 5 1
superpathway of vanillin and vanillate degradation 10 3 1
reductive TCA cycle I 11 7 1
enterobactin biosynthesis 11 5 1
L-glutamate degradation VIII (to propanoate) 11 3 1
reductive TCA cycle II 12 6 1
bacillibactin biosynthesis 12 4 1
syringate degradation 12 3 1
superpathway of purine nucleotides de novo biosynthesis II 26 26 2
Calvin-Benson-Bassham cycle 13 11 1
folate transformations I 13 10 1
peptidoglycan recycling I 14 11 1
purine nucleobases degradation I (anaerobic) 15 5 1
superpathway of arginine and polyamine biosynthesis 17 14 1
oxygenic photosynthesis 17 12 1
superpathway of L-threonine metabolism 18 15 1
hexitol fermentation to lactate, formate, ethanol and acetate 19 14 1
superpathway of N-acetylneuraminate degradation 22 16 1
superpathway of histidine, purine, and pyrimidine biosynthesis 46 46 2
purine nucleobases degradation II (anaerobic) 24 11 1
ethene biosynthesis V (engineered) 25 19 1
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) 26 21 1
1-butanol autotrophic biosynthesis (engineered) 27 20 1
Methanobacterium thermoautotrophicum biosynthetic metabolism 56 22 1