Experiment set4IT096 for Klebsiella michiganensis M5al

Compare to:

Potassium acetate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS01665 -6.6 -7.9 Isocitrate lyase (EC 4.1.3.1) (from data) conserved
BWI76_RS21475 -6.6 -6.4 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00855 -6.3 -7.5 argininosuccinate lyase compare
BWI76_RS02815 -6.3 -4.3 fructose-bisphosphatase class I compare
BWI76_RS23920 -6.1 -6.0 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04470 -6.1 -9.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS18950 -6.0 -5.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS25115 -5.9 -9.0 argininosuccinate synthase compare
BWI76_RS04645 -5.9 -6.9 3-dehydroquinase compare
BWI76_RS09760 -5.8 -4.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00805 -5.8 -5.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04250 -5.8 -8.9 homoserine kinase compare
BWI76_RS18935 -5.8 -7.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS05015 -5.8 -4.0 transcriptional regulator compare
BWI76_RS08425 -5.7 -5.1 succinyl-CoA ligase subunit beta compare
BWI76_RS04255 -5.7 -9.5 threonine synthase compare
BWI76_RS04465 -5.7 -5.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS08395 -5.6 -2.6 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS00850 -5.5 -9.5 acetylglutamate kinase compare
BWI76_RS27385 -5.3 -7.3 orotate phosphoribosyltransferase compare
BWI76_RS04160 -5.2 -8.7 phosphoserine phosphatase compare
BWI76_RS05840 -5.1 -6.1 glutamate 5-kinase compare
BWI76_RS09755 -5.1 -9.0 phosphoserine transaminase compare
BWI76_RS25420 -5.1 -10.1 malate dehydrogenase compare
BWI76_RS22805 -5.0 -11.2 GTP diphosphokinase compare
BWI76_RS26085 -4.9 -3.3 3-dehydroquinate synthase compare
BWI76_RS17720 -4.8 -2.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS18940 -4.8 -5.8 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS20160 -4.8 -4.0 NADH-quinone oxidoreductase subunit H compare
BWI76_RS18925 -4.8 -8.5 histidinol dehydrogenase compare
BWI76_RS23220 -4.7 -9.5 amino-acid N-acetyltransferase compare
BWI76_RS11965 -4.7 -5.5 orotidine-5'-phosphate decarboxylase compare
BWI76_RS08385 -4.7 -4.5 citrate (Si)-synthase compare
BWI76_RS04245 -4.7 -15.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00845 -4.6 -10.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS11840 -4.6 -5.5 tryptophan synthase subunit alpha compare
BWI76_RS18920 -4.6 -4.0 ATP phosphoribosyltransferase compare
BWI76_RS11850 -4.5 -10.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS02995 -4.5 -9.1 aspartate carbamoyltransferase compare
BWI76_RS00965 -4.4 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS01660 -4.4 -10.5 malate synthase A conserved
BWI76_RS08430 -4.2 -6.3 succinate--CoA ligase subunit alpha compare
BWI76_RS05835 -4.2 -3.6 gamma-glutamyl-phosphate reductase compare
BWI76_RS00990 -4.1 -9.0 ketol-acid reductoisomerase compare
BWI76_RS03010 -4.0 -8.6 ornithine carbamoyltransferase compare
BWI76_RS01615 -4.0 -10.6 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS18955 -4.0 -5.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS24285 -4.0 -7.7 cystathionine beta-lyase compare
BWI76_RS11845 -4.0 -3.8 tryptophan synthase subunit beta compare
BWI76_RS07070 -4.0 -7.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01655 -3.9 -8.9 homoserine O-succinyltransferase compare
BWI76_RS00975 -3.9 -12.4 dihydroxy-acid dehydratase compare
BWI76_RS20895 -3.8 -7.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS23360 -3.8 -3.4 diaminopimelate decarboxylase compare
BWI76_RS20150 -3.5 -3.7 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS20155 -3.5 -3.3 NADH-quinone oxidoreductase subunit I compare
BWI76_RS01210 -3.5 -3.5 tyrosine recombinase XerC compare
BWI76_RS20180 -3.5 -8.1 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS11860 -3.5 -6.7 anthranilate synthase component I compare
BWI76_RS20190 -3.5 -6.1 NADH-quinone oxidoreductase subunit A compare
BWI76_RS18930 -3.4 -2.5 histidinol-phosphate transaminase compare
BWI76_RS23830 -3.4 -9.4 hypothetical protein compare
BWI76_RS04670 -3.4 -9.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS09645 -3.4 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS20145 -3.3 -3.0 NADH-quinone oxidoreductase subunit K compare
BWI76_RS07065 -3.3 -10.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04665 -3.3 -17.9 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04685 -3.3 -13.6 putative leucine operon leader peptide compare
BWI76_RS08405 -3.3 -3.8 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS09910 -3.2 -16.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS00980 -3.2 -12.7 PLP-dependent threonine dehydratase compare
BWI76_RS20130 -3.2 -6.0 NADH-quinone oxidoreductase subunit N compare
BWI76_RS11855 -3.2 -4.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00785 -3.1 -8.3 cystathionine gamma-synthase compare
BWI76_RS20140 -3.1 -7.1 NADH-quinone oxidoreductase subunit L compare
BWI76_RS20170 -3.1 -5.6 NADH-quinone oxidoreductase subunit F compare
BWI76_RS21465 -3.0 -7.4 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04675 -3.0 -7.7 3-isopropylmalate dehydrogenase compare
BWI76_RS26000 -2.9 -9.0 aspartate aminotransferase family protein compare
BWI76_RS20350 -2.9 -8.1 amidophosphoribosyltransferase compare
BWI76_RS04705 -2.9 -7.4 DNA-binding transcriptional regulator FruR compare
BWI76_RS25300 -2.9 -4.3 hybrid sensor histidine kinase/response regulator compare
BWI76_RS23365 -2.9 -6.0 LysR family transcriptional regulator compare
BWI76_RS01185 -2.9 -2.8 adenylate cyclase compare
BWI76_RS20435 -2.9 -2.6 chorismate synthase compare
BWI76_RS22755 -2.8 -8.9 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00400 -2.8 -1.9 glutamine synthetase compare
BWI76_RS20355 -2.8 -3.6 colicin V production protein compare
BWI76_RS04240 -2.7 -4.4 thr operon leader peptide compare
BWI76_RS20965 -2.7 -4.8 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00985 -2.7 -8.5 transcriptional regulator IlvY compare
BWI76_RS21265 -2.7 -11.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04680 -2.7 -12.4 2-isopropylmalate synthase compare
BWI76_RS20135 -2.7 -6.3 NADH-quinone oxidoreductase subunit M compare
BWI76_RS20165 -2.6 -3.6 NADH-quinone oxidoreductase subunit G compare
BWI76_RS25355 -2.5 -7.2 cell division protein ZapE compare
BWI76_RS23240 -2.4 -4.5 exonuclease V subunit gamma compare
BWI76_RS09655 -2.4 -6.5 leucine-responsive regulatory protein compare
BWI76_RS08390 -2.4 -5.3 hypothetical protein compare
BWI76_RS27390 -2.3 -5.0 ribonuclease PH compare
BWI76_RS02410 -2.3 -3.0 EF-P beta-lysylation protein EpmB compare
BWI76_RS22690 -2.3 -2.4 adenylyl-sulfate kinase compare
BWI76_RS00345 -2.2 -4.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS11230 -2.2 -5.8 NAD-dependent deacylase conserved
BWI76_RS04510 -2.2 -2.3 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS01610 -2.2 -5.7 phosphoribosylamine--glycine ligase compare
BWI76_RS22765 -2.2 -9.6 sulfite reductase subunit alpha compare
BWI76_RS09640 -2.1 -5.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS22760 -2.1 -7.1 sulfite reductase subunit beta compare
BWI76_RS02095 -2.1 -9.7 acetyl-coenzyme A synthetase conserved
BWI76_RS06475 -2.1 -1.1 protoheme IX farnesyltransferase compare
BWI76_RS26455 -2.1 -4.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS15835 -2.1 -1.8 hypothetical protein compare
BWI76_RS09660 -2.1 -2.2 DNA translocase FtsK compare
BWI76_RS15825 -2.1 -2.1 hypothetical protein compare
BWI76_RS25320 -2.1 -6.4 glutamate synthase compare
BWI76_RS25315 -2.1 -10.2 glutamate synthase large subunit compare
BWI76_RS25960 -2.0 -4.9 NUDIX hydrolase compare
BWI76_RS05200 -2.0 -3.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS21565 -2.0 -2.1 outer membrane protein assembly factor BamE compare
BWI76_RS23230 -2.0 -3.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS26460 -1.9 -5.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS01350 -1.9 -2.0 NAD(P)H-flavin reductase compare
BWI76_RS27430 -1.8 -1.7 (p)ppGpp synthetase compare
BWI76_RS09615 -1.8 -3.0 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS16275 -1.8 -2.9 fumarate hydratase FumA compare
BWI76_RS08520 -1.8 -2.8 colicin transporter TolQ compare
BWI76_RS21480 -1.8 -3.1 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS09190 -1.7 -3.8 hypothetical protein compare
BWI76_RS25065 -1.7 -3.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS01200 -1.7 -2.0 diaminopimelate epimerase compare
BWI76_RS22845 -1.7 -6.4 flavodoxin conserved
BWI76_RS21140 -1.6 -2.5 molecular chaperone HscA compare
BWI76_RS01670 -1.6 -7.2 bifunctional isocitrate dehydrogenase kinase/phosphatase conserved
BWI76_RS20640 -1.6 -5.6 cysteine synthase A compare
BWI76_RS09650 -1.6 -6.1 hypothetical protein compare
BWI76_RS25070 -1.6 -1.9 hypothetical protein compare
BWI76_RS10990 -1.6 -1.5 dihydroorotase compare
BWI76_RS04525 -1.6 -1.5 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS07780 -1.6 -1.9 hypothetical protein compare
BWI76_RS27440 -1.6 -3.2 DNA helicase RecG compare
BWI76_RS08525 -1.5 -2.5 colicin transporter compare
BWI76_RS17065 -1.5 -7.0 phosphoenolpyruvate synthase compare
BWI76_RS15215 -1.5 -1.4 N-acetyltransferase compare
BWI76_RS20995 -1.5 -4.9 RNA degradosome polyphosphate kinase compare
BWI76_RS06525 -1.5 -5.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS20720 -1.5 -2.1 hypothetical protein compare
BWI76_RS27815 -1.4 -9.3 acetolactate synthase catalytic subunit compare
BWI76_RS03080 -1.4 -4.1 (Fe-S)-cluster assembly protein compare
BWI76_RS20970 -1.4 -1.8 phosphoribosylglycinamide formyltransferase compare
BWI76_RS19600 -1.3 -3.9 hypothetical protein compare
BWI76_RS06490 -1.3 -4.3 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS15060 -1.3 -3.5 MarR family transcriptional regulator compare
BWI76_RS05120 -1.3 -6.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS05450 -1.3 -2.0 ribonuclease HI compare
BWI76_RS03920 -1.2 -3.0 N-acetyltransferase compare
BWI76_RS01285 -1.2 -5.3 amino acid ABC transporter substrate-binding protein compare
BWI76_RS24075 -1.2 -3.8 glutathione synthase compare
BWI76_RS01070 -1.2 -5.7 thiol reductase thioredoxin compare
BWI76_RS27820 -1.2 -1.9 ilvB operon leader peptide IvbL compare
BWI76_RS23480 -1.2 -8.0 EAL domain-containing protein compare
BWI76_RS06485 -1.2 -2.5 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS01800 -1.2 -2.1 glucose-6-phosphate isomerase compare
BWI76_RS20270 -1.2 -5.9 hypothetical protein compare
BWI76_RS24900 -1.2 -1.6 DeoR family transcriptional regulator compare
BWI76_RS03415 -1.2 -4.5 LacI family transcriptional regulator compare
BWI76_RS00025 -1.1 -1.0 hypothetical protein compare
BWI76_RS06495 -1.1 -5.3 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS14835 -1.1 -1.3 hypothetical protein compare
BWI76_RS00180 -1.1 -1.0 F0F1 ATP synthase subunit epsilon compare
BWI76_RS21070 -1.1 -2.3 outer membrane protein assembly factor BamB compare
BWI76_RS26055 -1.1 -5.7 siroheme synthase compare
BWI76_RS26620 -1.1 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS15810 -1.1 -3.7 hypothetical protein compare
BWI76_RS21165 -1.0 -1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS18455 -1.0 -1.6 tRNA-Ser compare
BWI76_RS07675 -1.0 -4.0 DeoR family transcriptional regulator compare
BWI76_RS22240 -1.0 -3.5 transcriptional regulator compare
BWI76_RS25645 -1.0 -4.4 shikimate dehydrogenase compare
BWI76_RS23885 -1.0 -1.6 2-octaprenylphenol hydroxylase compare
BWI76_RS06185 -1.0 -5.8 shikimate kinase II compare
BWI76_RS23915 -1.0 -2.1 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS08205 -1.0 -3.6 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS08730 -1.0 -1.9 histidine utilization repressor compare
BWI76_RS21345 -1.0 -1.3 sigma-E factor regulatory protein RseB compare
BWI76_RS05790 -1.0 -1.6 phage DNA-binding protein compare
BWI76_RS01110 -1.0 -3.1 TDP-fucosamine acetyltransferase compare
BWI76_RS03225 -0.9 -4.6 transcriptional regulator compare
BWI76_RS21685 -0.9 -1.3 hypothetical protein compare
BWI76_RS19865 -0.9 -1.5 ecotin compare
BWI76_RS01385 -0.9 -2.3 potassium transporter compare
BWI76_RS26175 -0.9 -3.6 DeoR/GlpR family transcriptional regulator compare
BWI76_RS20440 -0.9 -3.5 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS15850 -0.9 -1.0 DUF1317 domain-containing protein compare
BWI76_RS20910 -0.9 -3.5 glycine cleavage system transcriptional repressor compare
BWI76_RS18575 -0.9 -2.3 transcriptional regulator compare
BWI76_RS12375 -0.9 -2.8 DNA-invertase hin compare
BWI76_RS15660 -0.9 -0.8 hypothetical protein compare
BWI76_RS00970 -0.9 -1.9 branched chain amino acid aminotransferase compare
BWI76_RS15605 -0.9 -1.8 hypothetical protein compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Potassium acetate in Klebsiella michiganensis M5al

For carbon source Potassium acetate across organisms