Experiment set4IT095 for Methanococcus maripaludis S2

Compare to:

Formate deepwell autotrophic conditions

200 most important genes:

  gene name fitness t score description  
MMP_RS04615 -9.9 -4.5 PDGLE domain-containing protein compare
MMP_RS05060 -9.6 -13.2 AAA family ATPase compare
MMP_RS03015 -9.5 -6.6 GTP 3' 8-cyclase MoaA compare
MMP_RS06705 -9.3 -6.1 formate/nitrite transporter family protein compare
MMP_RS05100 -9.3 -18.8 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05080 -9.1 -14.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS05090 -9.0 -10.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06355 -8.9 -3.5 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06715 -8.7 -15.8 cache domain-containing protein compare
MMP_RS05055 -8.6 -17.5 DUF166 domain-containing protein compare
MMP_RS01175 -8.6 -4.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04620 -8.4 -12.9 cobalt transporter CbiM compare
MMP_RS01500 -8.4 -3.2 CBS domain-containing protein compare
MMP_RS05085 -8.3 -11.2 AAA family ATPase compare
MMP_RS06680 -8.2 -14.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06975 -8.1 -3.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05075 -8.0 -17.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05515 -7.9 -7.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05095 -7.9 -8.1 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS05070 -7.8 -7.6 4Fe-4S dicluster domain-containing protein compare
MMP_RS07345 -7.7 -5.3 glycine synthesis protein GlyXL (from data) compare
MMP_RS07445 -7.7 -10.4 helix-turn-helix domain-containing protein compare
MMP_RS05065 -7.6 -6.0 CooT family nickel-binding protein compare
MMP_RS06350 -7.6 -7.2 HesA/MoeB/ThiF family protein compare
MMP_RS01455 -7.5 -7.9 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS06375 -7.4 -5.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS03640 -7.3 -4.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06700 -7.3 -14.6 hypothetical protein compare
MMP_RS06685 -7.2 -16.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04605 -7.2 -5.3 cobalt ECF transporter T component CbiQ compare
MMP_RS06730 -6.9 -3.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS03450 -6.9 -3.2 glycine synthesis protein GlyXS (from data) compare
MMP_RS05500 -6.7 -10.4 2-isopropylmalate synthase compare
MMP_RS07845 -6.7 -3.5 LL-diaminopimelate aminotransferase compare
MMP_RS08790 -6.7 -2.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS04215 -6.7 -8.0 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS07365 -6.7 -12.1 2-phosphoglycerate kinase compare
MMP_RS01380 -6.6 -5.5 PHP domain-containing protein compare
MMP_RS06720 -6.4 -6.3 response regulator transcription factor compare
MMP_RS07605 -6.3 -4.0 diadenylate cyclase compare
MMP_RS05925 -6.3 -5.4 small nuclear ribonucleoprotein compare
MMP_RS01545 -6.3 -1.4 CBS domain-containing protein compare
MMP_RS02195 -6.3 -5.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06340 -6.2 -8.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08745 -6.1 -7.3 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06370 -6.1 -6.5 biotin synthase BioB compare
MMP_RS07630 -6.0 -2.3 ATP-binding cassette domain-containing protein compare
MMP_RS06895 -5.9 -3.0 selenocysteine-specific translation elongation factor compare
MMP_RS01020 -5.9 -1.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06345 -5.9 -9.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07720 -5.9 -15.4 4Fe-4S binding protein compare
MMP_RS00295 -5.8 -2.6 gamma carbonic anhydrase family protein compare
MMP_RS03315 -5.7 -2.2 ferrous iron transport protein A compare
MMP_RS01265 -5.6 -4.5 hypothetical protein compare
MMP_RS08715 -5.5 -3.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS05265 -5.5 -3.0 2-isopropylmalate synthase compare
MMP_RS03035 -5.5 -6.1 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06270 -5.4 -7.2 TIGR00300 family protein compare
MMP_RS07185 -5.4 -15.7 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02145 -5.3 -9.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS09020 -5.3 -2.7 hypothetical protein compare
MMP_RS08635 -5.2 -2.8 UbiA family prenyltransferase compare
MMP_RS04780 -5.1 -4.3 ribonuclease P compare
MMP_RS03435 -5.0 -2.9 ketol-acid reductoisomerase compare
MMP_RS01225 -5.0 -7.6 DUF5379 domain-containing protein compare
MMP_RS07525 -5.0 -5.9 4Fe-4S binding protein compare
MMP_RS02900 -5.0 -1.1 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS05425 -4.8 -7.4 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS07380 -4.8 -3.9 transcription elongation factor Spt5 compare
MMP_RS06400 -4.8 -2.6 4Fe-4S binding protein compare
MMP_RS04500 -4.8 -19.2 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS08105 -4.8 -9.9 6-carboxyhexanoate--CoA ligase compare
MMP_RS08645 -4.8 -9.3 UPF0179 family protein compare
MMP_RS08240 -4.8 -7.4 methanogenesis marker 16 metalloprotein compare
MMP_RS07390 -4.7 -3.8 cell division protein FtsZ compare
MMP_RS00300 -4.7 -1.1 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06295 -4.7 -10.0 methanogenesis marker 14 protein compare
MMP_RS01800 -4.7 -6.3 TIGR00303 family protein compare
MMP_RS08820 -4.7 -7.1 hypothetical protein compare
MMP_RS05550 -4.7 -1.0 cation:proton antiporter compare
MMP_RS05920 -4.6 -1.0 50S ribosomal protein L37e compare
MMP_RS03600 -4.6 -3.3 triose-phosphate isomerase compare
MMP_RS00290 -4.6 -10.1 hypothetical protein compare
MMP_RS07730 -4.5 -3.1 pyruvate synthase subunit beta compare
MMP_RS07645 -4.4 -10.2 aldehyde dehydrogenase family protein compare
MMP_RS06630 -4.4 -1.4 UPF0058 family protein compare
MMP_RS05930 -4.4 -3.7 3-isopropylmalate dehydratase large subunit compare
MMP_RS00455 -4.4 -10.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS08100 -4.4 -9.1 8-amino-7-oxononanoate synthase compare
MMP_RS06315 -4.4 -1.4 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08720 -4.3 -2.4 4Fe-4S binding protein compare
MMP_RS06230 -4.3 -4.6 helix-turn-helix domain-containing protein compare
MMP_RS03960 -4.3 -1.4 hypothetical protein compare
MMP_RS05850 -4.3 -7.1 Ldh family oxidoreductase compare
MMP_RS08210 -4.3 -3.2 phosphatidylglycerophosphatase A compare
MMP_RS02340 -4.3 -2.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01700 -4.3 -1.3 dihydroxy-acid dehydratase compare
MMP_RS07575 -4.2 -3.9 RNA ligase partner protein compare
MMP_RS06625 -4.2 -3.5 DNA primase compare
MMP_RS00305 -4.2 -3.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS08095 -4.1 -7.6 dethiobiotin synthase compare
MMP_RS00685 -4.1 -6.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07635 -4.1 -9.3 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07195 -4.1 -12.1 M20 family metallo-hydrolase compare
MMP_RS01005 -4.1 -1.7 riboflavin synthase compare
MMP_RS04585 -4.1 -11.3 AIR synthase related protein compare
MMP_RS08440 -4.1 -4.8 cell division protein SepF compare
MMP_RS01475 -4.1 -6.1 phosphosulfolactate synthase compare
MMP_RS06930 -4.0 -15.8 MBL fold metallo-hydrolase compare
MMP_RS08460 -4.0 -3.6 proteasome-activating nucleotidase compare
MMP_RS01755 -4.0 -1.8 DUF2097 domain-containing protein compare
MMP_RS06120 -4.0 -3.2 UPF0147 family protein compare
MMP_RS01980 -3.9 -18.8 trimeric intracellular cation channel family protein compare
MMP_RS04890 -3.9 -1.2 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03580 -3.9 -4.2 signal recognition particle-docking protein FtsY compare
MMP_RS06285 -3.9 -3.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08650 -3.9 -5.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01795 -3.8 -2.6 methanogenesis marker 6 protein compare
MMP_RS07555 -3.8 -1.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS01830 -3.7 -2.0 tRNA-Val compare
MMP_RS05440 -3.7 -9.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS01925 -3.6 -10.3 DUF1616 domain-containing protein compare
MMP_RS07545 -3.5 -1.5 HTH domain-containing protein compare
MMP_RS01325 -3.5 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS04710 -3.5 -2.5 hypothetical protein compare
MMP_RS01610 -3.5 -4.8 hypothetical protein compare
MMP_RS01985 -3.5 -9.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07005 -3.4 -1.1 4Fe-4S binding protein compare
MMP_RS00985 -3.4 -6.0 CDC48 family AAA ATPase compare
MMP_RS03420 -3.3 -1.6 acetolactate synthase small subunit compare
MMP_RS01955 -3.3 -3.6 hypothetical protein compare
MMP_RS06020 -3.3 -5.9 archaeoflavoprotein AfpA compare
MMP_RS03475 -3.3 -1.0 hypothetical protein compare
MMP_RS03025 -3.3 -6.5 molybdenum cofactor guanylyltransferase compare
MMP_RS04090 -3.3 -4.8 hypothetical protein compare
MMP_RS08165 -3.3 -3.9 phosphoglycerate dehydrogenase compare
MMP_RS02355 -3.3 -3.2 30S ribosomal protein S27ae compare
MMP_RS02345 -3.2 -5.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00515 -3.2 -1.4 DUF655 domain-containing protein compare
MMP_RS05555 -3.2 -2.0 DUF4040 domain-containing protein compare
MMP_RS07735 -3.1 -1.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07600 -3.1 -2.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07580 -3.1 -4.8 DUF356 domain-containing protein compare
MMP_RS03700 -3.1 -11.4 sodium:proton antiporter compare
MMP_RS01905 -3.1 -14.9 glycosyltransferase compare
MMP_RS01895 -3.0 -16.0 flippase compare
MMP_RS08330 -3.0 -5.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS02240 -3.0 -3.9 methanogenesis marker 7 protein compare
MMP_RS05280 -3.0 -11.3 COG1361 S-layer family protein compare
MMP_RS01915 -2.9 -15.8 DUF354 domain-containing protein compare
MMP_RS05285 -2.9 -10.6 MMPL family transporter compare
MMP_RS04790 -2.9 -13.9 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01900 -2.8 -13.6 hypothetical protein compare
MMP_RS05845 -2.8 -3.2 tRNA-intron lyase compare
MMP_RS03110 -2.8 -8.6 glycosyltransferase family 2 protein compare
MMP_RS02280 -2.8 -1.4 DUF211 domain-containing protein compare
MMP_RS05765 -2.8 -6.9 M42 family metallopeptidase compare
MMP_RS05505 -2.8 -10.4 class IV adenylate cyclase compare
MMP_RS00115 -2.7 -14.8 radical SAM protein compare
MMP_RS05345 -2.7 -8.6 hypothetical protein compare
MMP_RS00620 -2.7 -10.5 4Fe-4S binding protein compare
MMP_RS06925 -2.7 -3.7 ribonuclease VapC4 compare
MMP_RS03445 -2.6 -1.5 methanogenesis marker 17 protein compare
MMP_RS01385 -2.6 -1.0 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04685 -2.6 -3.7 DUF126 domain-containing protein compare
MMP_RS01910 -2.6 -11.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS06175 -2.6 -6.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS01220 -2.5 -7.8 hypothetical protein compare
MMP_RS03155 -2.5 -10.0 precorrin-6A reductase compare
MMP_RS07710 -2.5 -11.5 cell division protein FtsZ compare
MMP_RS08300 -2.4 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS02170 -2.4 -6.7 CBS domain-containing protein compare
MMP_RS06105 -2.4 -9.8 hydrogenase maturation peptidase HycI compare
MMP_RS02875 -2.4 -14.6 chorismate pyruvate-lyase family protein compare
MMP_RS07200 -2.4 -6.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06215 -2.3 -3.7 30S ribosomal protein S6e compare
MMP_RS07075 -2.3 -4.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS05245 -2.3 -12.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08320 -2.3 -3.7 molybdopterin molybdotransferase MoeA compare
MMP_RS00320 -2.3 -2.3 class I SAM-dependent methyltransferase compare
MMP_RS03140 -2.3 -12.9 hypothetical protein compare
MMP_RS07875 -2.3 -5.7 hypothetical protein compare
MMP_RS02800 -2.3 -5.6 nucleotidyltransferase domain-containing protein compare
MMP_RS05430 -2.2 -5.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS08445 -2.2 -5.7 DUF2099 family protein compare
MMP_RS06130 -2.2 -4.7 peptidylprolyl isomerase compare
MMP_RS01365 -2.2 -2.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07685 -2.2 -10.2 TIGR01212 family radical SAM protein compare
MMP_RS06770 -2.1 -10.5 DHH family phosphoesterase compare
MMP_RS02010 -2.1 -10.9 PHP domain-containing protein compare
MMP_RS01880 -2.1 -6.3 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03145 -2.1 -8.1 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS04870 -2.1 -5.3 TIGR02253 family HAD-type hydrolase compare
MMP_RS02190 -2.1 -2.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01875 -2.1 -7.6 N-acetyltransferase compare
MMP_RS03205 -2.0 -1.9 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01885 -2.0 -7.7 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS03400 -2.0 -3.6 archease compare
MMP_RS01920 -1.9 -13.1 glycosyltransferase family 2 protein compare
MMP_RS05540 -1.9 -2.8 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment