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Experiment set4IT094 for
Methanococcus maripaludis S2
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Formate deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS05065
-9.9
-5.1
CooT family nickel-binding protein
compare
MMP
_RS05080
-9.3
-14.8
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS03015
-9.3
-9.0
GTP 3' 8-cyclase MoaA
compare
MMP
_RS05515
-9.0
-7.6
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06350
-9.0
-6.5
HesA/MoeB/ThiF family protein
compare
MMP
_RS05055
-8.8
-17.0
DUF166 domain-containing protein
compare
MMP
_RS05070
-8.7
-11.0
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS03450
-8.7
-3.5
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS01175
-8.7
-4.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS05060
-8.7
-11.8
AAA family ATPase
compare
MMP
_RS05100
-8.6
-23.6
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS01500
-8.5
-3.4
CBS domain-containing protein
compare
MMP
_RS05085
-8.5
-10.8
AAA family ATPase
compare
MMP
_RS04615
-8.4
-4.8
PDGLE domain-containing protein
compare
MMP
_RS05090
-8.4
-12.5
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS05095
-8.4
-6.9
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS04605
-8.3
-5.3
cobalt ECF transporter T component CbiQ
compare
MMP
_RS06715
-8.3
-18.5
cache domain-containing protein
compare
MMP
_RS04620
-8.3
-14.9
cobalt transporter CbiM
compare
MMP
_RS06975
-8.3
-3.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS06895
-8.1
-3.2
selenocysteine-specific translation elongation factor
compare
MMP
_RS06285
-7.9
-3.7
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06680
-7.9
-15.2
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS05500
-7.9
-10.6
2-isopropylmalate synthase
compare
MMP
_RS06705
-7.7
-8.3
formate/nitrite transporter family protein
compare
MMP
_RS07845
-7.7
-3.8
LL-diaminopimelate aminotransferase
compare
MMP
_RS06700
-7.6
-16.0
hypothetical protein
compare
MMP
_RS07345
-7.5
-7.3
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS05075
-7.5
-16.4
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS07445
-7.5
-11.0
helix-turn-helix domain-containing protein
compare
MMP
_RS03640
-7.5
-4.9
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS06270
-7.4
-8.8
TIGR00300 family protein
compare
MMP
_RS06400
-7.3
-3.0
4Fe-4S binding protein
compare
MMP
_RS06355
-7.3
-3.8
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS06685
-7.3
-17.0
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06720
-7.2
-6.4
response regulator transcription factor
compare
MMP
_RS06730
-7.1
-3.3
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS07365
-7.0
-12.4
2-phosphoglycerate kinase
compare
MMP
_RS06625
-7.0
-3.3
DNA primase
compare
MMP
_RS00295
-6.5
-2.1
gamma carbonic anhydrase family protein
compare
MMP
_RS01545
-6.4
-1.5
CBS domain-containing protein
compare
MMP
_RS03435
-6.4
-2.9
ketol-acid reductoisomerase
compare
MMP
_RS07380
-6.4
-3.3
transcription elongation factor Spt5
compare
MMP
_RS06345
-6.2
-12.2
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS01455
-6.2
-7.9
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS05930
-6.2
-4.0
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS01380
-6.1
-7.9
PHP domain-containing protein
compare
MMP
_RS06375
-6.1
-7.5
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS01020
-6.1
-1.4
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS07730
-6.0
-3.1
pyruvate synthase subunit beta
compare
MMP
_RS08240
-5.9
-9.0
methanogenesis marker 16 metalloprotein
compare
MMP
_RS03315
-5.9
-2.3
ferrous iron transport protein A
compare
MMP
_RS08645
-5.8
-10.6
UPF0179 family protein
compare
MMP
_RS05925
-5.7
-5.6
small nuclear ribonucleoprotein
compare
MMP
_RS04215
-5.7
-10.1
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS03035
-5.6
-5.4
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS02145
-5.6
-9.3
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS08745
-5.5
-10.6
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS00305
-5.5
-2.8
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS03600
-5.4
-3.8
triose-phosphate isomerase
compare
MMP
_RS06340
-5.4
-7.8
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS04780
-5.3
-4.5
ribonuclease P
compare
MMP
_RS08210
-5.3
-3.8
phosphatidylglycerophosphatase A
compare
MMP
_RS01005
-5.2
-1.7
riboflavin synthase
compare
MMP
_RS07720
-5.0
-12.9
4Fe-4S binding protein
compare
MMP
_RS01755
-4.9
-1.6
DUF2097 domain-containing protein
compare
MMP
_RS07005
-4.9
-1.1
4Fe-4S binding protein
compare
MMP
_RS06930
-4.9
-18.0
MBL fold metallo-hydrolase
compare
MMP
_RS07605
-4.9
-4.0
diadenylate cyclase
compare
MMP
_RS00300
-4.8
-1.1
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS06120
-4.8
-3.3
UPF0147 family protein
compare
MMP
_RS08460
-4.8
-3.9
proteasome-activating nucleotidase
compare
MMP
_RS03445
-4.8
-1.6
methanogenesis marker 17 protein
compare
MMP
_RS00290
-4.8
-8.9
hypothetical protein
compare
MMP
_RS08095
-4.8
-9.2
dethiobiotin synthase
compare
MMP
_RS00455
-4.7
-16.2
orotate phosphoribosyltransferase-like protein
compare
MMP
_RS07635
-4.7
-10.7
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS07645
-4.7
-8.0
aldehyde dehydrogenase family protein
compare
MMP
_RS08105
-4.7
-9.1
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS07185
-4.7
-13.3
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS01830
-4.7
-2.6
tRNA-Val
compare
MMP
_RS06295
-4.6
-9.2
methanogenesis marker 14 protein
compare
MMP
_RS06630
-4.6
-1.5
UPF0058 family protein
compare
MMP
_RS08720
-4.6
-2.9
4Fe-4S binding protein
compare
MMP
_RS06370
-4.5
-8.8
biotin synthase BioB
compare
MMP
_RS06315
-4.5
-1.5
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS04500
-4.5
-19.4
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS08100
-4.4
-8.2
8-amino-7-oxononanoate synthase
compare
MMP
_RS07525
-4.4
-7.0
4Fe-4S binding protein
compare
MMP
_RS05265
-4.4
-3.5
2-isopropylmalate synthase
compare
MMP
_RS01700
-4.3
-1.4
dihydroxy-acid dehydratase
compare
MMP
_RS08820
-4.3
-7.2
hypothetical protein
compare
MMP
_RS01985
-4.3
-10.8
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS05555
-4.3
-2.0
DUF4040 domain-containing protein
compare
MMP
_RS08715
-4.2
-3.1
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS01475
-4.2
-6.1
phosphosulfolactate synthase
compare
MMP
_RS04585
-4.1
-11.7
AIR synthase related protein
compare
MMP
_RS00515
-4.1
-1.3
DUF655 domain-containing protein
compare
MMP
_RS04890
-4.0
-1.3
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS01225
-4.0
-7.1
DUF5379 domain-containing protein
compare
MMP
_RS05850
-3.9
-7.7
Ldh family oxidoreductase
compare
MMP
_RS08790
-3.9
-3.4
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS02195
-3.9
-5.2
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS09020
-3.8
-3.0
hypothetical protein
compare
MMP
_RS07735
-3.8
-1.2
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01925
-3.8
-12.4
DUF1616 domain-containing protein
compare
MMP
_RS05765
-3.8
-7.8
M42 family metallopeptidase
compare
MMP
_RS03960
-3.8
-1.5
hypothetical protein
compare
MMP
_RS02280
-3.8
-1.5
DUF211 domain-containing protein
compare
MMP
_RS06230
-3.8
-3.7
helix-turn-helix domain-containing protein
compare
MMP
_RS01610
-3.7
-4.7
hypothetical protein
compare
MMP
_RS05440
-3.7
-14.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS00685
-3.7
-6.6
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS01800
-3.7
-6.3
TIGR00303 family protein
compare
MMP
_RS01325
-3.6
-3.5
dihydroneopterin aldolase family protein
compare
MMP
_RS07195
-3.6
-14.4
M20 family metallo-hydrolase
compare
MMP
_RS01980
-3.5
-18.6
trimeric intracellular cation channel family protein
compare
MMP
_RS04685
-3.5
-5.2
DUF126 domain-containing protein
compare
MMP
_RS02355
-3.5
-4.8
30S ribosomal protein S27ae
compare
MMP
_RS07575
-3.5
-7.6
RNA ligase partner protein
compare
MMP
_RS05425
-3.5
-6.1
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS05550
-3.5
-1.1
cation:proton antiporter
compare
MMP
_RS04710
-3.4
-2.4
hypothetical protein
compare
MMP
_RS07630
-3.4
-2.0
ATP-binding cassette domain-containing protein
compare
MMP
_RS01960
-3.3
-1.1
hypothetical protein
compare
MMP
_RS03420
-3.2
-2.6
acetolactate synthase small subunit
compare
MMP
_RS08635
-3.2
-3.2
UbiA family prenyltransferase
compare
MMP
_RS01955
-3.2
-5.0
hypothetical protein
compare
MMP
_RS00895
-3.2
-5.6
hypothetical protein
compare
MMP
_RS07390
-3.1
-3.5
cell division protein FtsZ
compare
MMP
_RS03025
-3.1
-8.0
molybdenum cofactor guanylyltransferase
compare
MMP
_RS08300
-3.1
-1.6
metal-sulfur cluster assembly factor
compare
MMP
_RS02345
-3.1
-5.8
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS08330
-3.1
-6.0
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS00115
-3.1
-17.8
radical SAM protein
compare
MMP
_RS01895
-3.1
-15.2
flippase
compare
MMP
_RS00985
-3.0
-6.8
CDC48 family AAA ATPase
compare
MMP
_RS05505
-3.0
-12.7
class IV adenylate cyclase
compare
MMP
_RS05285
-3.0
-14.6
MMPL family transporter
compare
MMP
_RS01265
-3.0
-4.1
hypothetical protein
compare
MMP
_RS07710
-3.0
-12.6
cell division protein FtsZ
compare
MMP
_RS03580
-3.0
-4.3
signal recognition particle-docking protein FtsY
compare
MMP
_RS03700
-3.0
-10.4
sodium:proton antiporter
compare
MMP
_RS02340
-3.0
-2.4
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS08165
-2.9
-3.8
phosphoglycerate dehydrogenase
compare
MMP
_RS06020
-2.9
-6.4
archaeoflavoprotein AfpA
compare
MMP
_RS02240
-2.9
-5.3
methanogenesis marker 7 protein
compare
MMP
_RS03110
-2.9
-8.0
glycosyltransferase family 2 protein
compare
MMP
_RS05280
-2.9
-13.4
COG1361 S-layer family protein
compare
MMP
_RS05845
-2.9
-3.5
tRNA-intron lyase
compare
MMP
_RS04790
-2.8
-15.5
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS08650
-2.8
-4.4
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS01900
-2.8
-15.5
hypothetical protein
compare
MMP
_RS01385
-2.8
-1.1
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS03475
-2.8
-1.1
hypothetical protein
compare
MMP
_RS02170
-2.8
-6.5
CBS domain-containing protein
compare
MMP
_RS01905
-2.8
-14.7
glycosyltransferase
compare
MMP
_RS07555
-2.8
-1.2
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS01915
-2.7
-14.6
DUF354 domain-containing protein
compare
MMP
_RS04870
-2.7
-5.3
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS02900
-2.7
-1.2
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS07200
-2.6
-8.6
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS03400
-2.6
-5.0
archease
compare
MMP
_RS06215
-2.6
-5.1
30S ribosomal protein S6e
compare
MMP
_RS02875
-2.6
-11.3
chorismate pyruvate-lyase family protein
compare
MMP
_RS05245
-2.6
-12.9
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS04090
-2.6
-4.0
hypothetical protein
compare
MMP
_RS07600
-2.6
-3.3
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06105
-2.5
-10.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS01220
-2.5
-7.9
hypothetical protein
compare
MMP
_RS01910
-2.5
-11.9
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS08435
-2.5
-2.6
Era-like GTP-binding protein
compare
MMP
_RS05430
-2.5
-4.8
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS07580
-2.5
-4.2
DUF356 domain-containing protein
compare
MMP
_RS07545
-2.5
-1.6
HTH domain-containing protein
compare
MMP
_RS06175
-2.5
-9.3
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03155
-2.4
-10.4
precorrin-6A reductase
compare
MMP
_RS07685
-2.4
-8.4
TIGR01212 family radical SAM protein
compare
MMP
_RS06925
-2.4
-3.3
ribonuclease VapC4
compare
MMP
_RS02800
-2.4
-5.0
nucleotidyltransferase domain-containing protein
compare
MMP
_RS08440
-2.4
-3.3
cell division protein SepF
compare
MMP
_RS00620
-2.4
-12.9
4Fe-4S binding protein
compare
MMP
_RS03145
-2.3
-7.6
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS01880
-2.3
-9.3
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS00695
-2.3
-1.4
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS03140
-2.3
-12.5
hypothetical protein
compare
MMP
_RS02135
-2.3
-5.1
DUF5612 domain-containing protein
compare
MMP
_RS01365
-2.2
-2.6
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS07075
-2.2
-4.6
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS00320
-2.2
-2.4
class I SAM-dependent methyltransferase
compare
MMP
_RS08445
-2.2
-5.5
DUF2099 family protein
compare
MMP
_RS06130
-2.1
-5.3
peptidylprolyl isomerase
compare
MMP
_RS00130
-2.1
-2.0
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS05540
-2.1
-3.7
hypothetical protein
compare
MMP
_RS05345
-2.1
-7.6
hypothetical protein
compare
MMP
_RS07420
-2.0
-3.6
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS06980
-2.0
-7.7
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS04775
-2.0
-4.6
adenosylhomocysteinase
compare
MMP
_RS07875
-2.0
-6.5
hypothetical protein
compare
MMP
_RS05920
-2.0
-1.0
50S ribosomal protein L37e
compare
Specific Phenotypes
For 1 genes in this experiment