Experiment set4IT090 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Methionine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -3.2 -4.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_15 -2.9 -2.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_3546 -2.8 -2.6 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_2880 -2.7 -10.1 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1611 -2.6 -4.9 Nitrogen regulation protein NR(I) compare
Pf1N1B4_1408 -2.6 -3.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1831 -2.6 -8.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_1626 -2.5 -5.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_1830 -2.5 -7.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_1624 -2.5 -7.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_2303 -2.4 -11.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1067 -2.4 -5.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_3768 -2.3 -3.0 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_583 -2.3 -2.6 FIG00957748: hypothetical protein compare
Pf1N1B4_2282 -2.3 -7.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2548 -2.3 -5.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2272 -2.3 -2.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_2010 -2.2 -5.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_58 -2.2 -5.5 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_1627 -2.2 -3.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_1610 -2.1 -3.4 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_3751 -2.1 -2.2 FIG00953060: hypothetical protein compare
Pf1N1B4_1307 -2.1 -2.4 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_4921 -2.1 -2.5 Haloacid dehalogenase, type II compare
Pf1N1B4_1565 -2.1 -3.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_5386 -2.0 -2.3 hypothetical protein compare
Pf1N1B4_2112 -2.0 -11.4 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_762 -2.0 -4.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_1234 -2.0 -3.4 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_742 -2.0 -6.7 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_350 -2.0 -6.1 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_12 -1.9 -5.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_2823 -1.9 -2.1 COG1496: Uncharacterized conserved protein compare
Pf1N1B4_4437 -1.9 -3.4 hypothetical protein compare
Pf1N1B4_2545 -1.9 -10.5 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1317 -1.9 -2.7 Sensor histidine kinase/response regulator compare
Pf1N1B4_3833 -1.9 -6.4 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_1434 -1.9 -5.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2009 -1.8 -3.8 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1534 -1.8 -12.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_3001 -1.8 -3.2 hypothetical protein compare
Pf1N1B4_3656 -1.8 -2.2 Eukaryotic-type low-affinity urea transporter compare
Pf1N1B4_4668 -1.8 -3.2 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_1315 -1.8 -6.2 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_5279 -1.8 -2.5 hypothetical protein compare
Pf1N1B4_4358 -1.8 -2.3 Acetyltransferase, GNAT family compare
Pf1N1B4_3729 -1.8 -2.2 Quaternary ammonium compound-resistance protein SugE compare
Pf1N1B4_5446 -1.7 -3.3 hypothetical protein compare
Pf1N1B4_1661 -1.7 -4.2 Agmatine deiminase (EC 3.5.3.12) compare
Pf1N1B4_2352 -1.7 -4.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf1N1B4_5507 -1.7 -2.6 hypothetical protein compare
Pf1N1B4_4156 -1.7 -2.5 putative secreted protein compare
Pf1N1B4_3889 -1.7 -1.9 hypothetical protein compare
Pf1N1B4_4481 -1.7 -2.8 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_1625 -1.7 -4.2 FIG00956267: hypothetical protein compare
Pf1N1B4_2547 -1.7 -2.6 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1579 -1.7 -3.7 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
Pf1N1B4_4531 -1.6 -2.1 FIG01221261: hypothetical protein compare
Pf1N1B4_3081 -1.6 -12.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_3499 -1.6 -1.7 hypothetical protein compare
Pf1N1B4_2011 -1.5 -5.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_2878 -1.5 -6.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_2280 -1.5 -6.2 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_2501 -1.5 -6.9 Pyrroloquinoline-quinone synthase (EC 1.3.3.11) compare
Pf1N1B4_3582 -1.5 -1.6 C-methyltransferase compare
Pf1N1B4_4833 -1.5 -2.8 DNA-binding response regulator, LuxR family compare
Pf1N1B4_3775 -1.5 -2.2 FIG00956876: hypothetical protein compare
Pf1N1B4_847 -1.5 -5.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_4671 -1.5 -2.5 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_4139 -1.4 -1.5 Transcriptional regulator, MerR family compare
Pf1N1B4_4596 -1.4 -2.4 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
Pf1N1B4_5622 -1.4 -2.6 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_4484 -1.4 -4.1 FIG002984: FAD-dependent pyridine nucleotide-disulphide oxidoreductase compare
Pf1N1B4_765 -1.4 -2.3 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_5329 -1.4 -2.5 hypothetical protein compare
Pf1N1B4_5722 -1.4 -2.0 Periplasmic protein p19 involved in high-affinity Fe2+ transport compare
Pf1N1B4_5074 -1.4 -1.9 Gluconate permease compare
Pf1N1B4_1052 -1.3 -2.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_4678 -1.3 -3.4 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf1N1B4_4482 -1.3 -1.6 FIG146518: Zn-dependent hydrolases, including glyoxylases compare
Pf1N1B4_2488 -1.3 -5.3 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_5768 -1.3 -2.3 Heme d1 biosynthesis protein NirD compare
Pf1N1B4_4549 -1.3 -2.4 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
Pf1N1B4_4939 -1.3 -2.4 sodium/hydrogen exchanger family protein compare
Pf1N1B4_4299 -1.3 -2.6 sensor histidine kinase compare
Pf1N1B4_981 -1.3 -2.3 UPF0246 protein YaaA compare
Pf1N1B4_2208 -1.3 -5.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf1N1B4_4198 -1.3 -2.2 4-hydroxybenzoate transporter compare
Pf1N1B4_4931 -1.3 -1.9 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_5591 -1.3 -1.9 Vanillin dehydrogenase (Hydroxybenzaldehyde dehydrogenase) (EC 1.2.1.28) compare
Pf1N1B4_5777 -1.3 -2.5 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf1N1B4_2885 -1.3 -4.2 Paraquat-inducible protein A compare
Pf1N1B4_4494 -1.3 -2.7 hypothetical protein compare
Pf1N1B4_5976 -1.2 -1.5 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) compare
Pf1N1B4_5331 -1.2 -2.0 hypothetical protein compare
Pf1N1B4_1619 -1.2 -6.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf1N1B4_3091 -1.2 -3.3 Membrane-associated zinc metalloprotease compare
Pf1N1B4_1533 -1.2 -5.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_3485 -1.2 -1.5 hypothetical protein compare
Pf1N1B4_602 -1.2 -2.2 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf1N1B4_722 -1.2 -1.8 SAM-dependent methyltransferases compare
Pf1N1B4_1065 -1.2 -4.2 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
Pf1N1B4_702 -1.2 -3.4 Transcriptional regulator PobR, AraC family compare
Pf1N1B4_3356 -1.2 -1.8 Cyclic nucleotide-binding protein compare
Pf1N1B4_2005 -1.2 -1.5 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_2499 -1.2 -5.6 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_2322 -1.2 -1.7 FIG015547: peptidase, M16 family compare
Pf1N1B4_1236 -1.2 -3.9 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_231 -1.2 -3.4 Sensor histidine kinase compare
Pf1N1B4_4828 -1.2 -2.6 hypothetical protein compare
Pf1N1B4_2487 -1.2 -5.3 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_4212 -1.2 -1.9 Gfa-like protein compare
Pf1N1B4_2360 -1.2 -1.7 hypothetical protein compare
Pf1N1B4_3253 -1.2 -3.0 Acyl carrier protein phosphodiesterase (EC 3.1.4.14) compare
Pf1N1B4_1781 -1.2 -1.4 hypothetical protein compare
Pf1N1B4_4219 -1.2 -2.2 FIG01074225: hypothetical protein compare
Pf1N1B4_5505 -1.1 -2.4 hypothetical protein compare
Pf1N1B4_5082 -1.1 -2.5 Capsular polysaccharide synthesis enzyme CpsB compare
Pf1N1B4_4177 -1.1 -1.5 transcriptional regulator, Crp/Fnr family compare
Pf1N1B4_501 -1.1 -1.2 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_2283 -1.1 -1.6 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_5884 -1.1 -1.3 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf1N1B4_1906 -1.1 -2.6 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_4648 -1.1 -1.6 transcriptional regulator, MerR family compare
Pf1N1B4_4476 -1.1 -2.5 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf1N1B4_5904 -1.1 -1.6 FIG00955320: hypothetical protein compare
Pf1N1B4_234 -1.1 -2.4 hypothetical protein compare
Pf1N1B4_1008 -1.1 -1.2 FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_1243 -1.1 -2.5 ABC transporter ATP-binding protein compare
Pf1N1B4_1153 -1.1 -2.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_3745 -1.1 -1.9 Thiamin ABC transporter, transmembrane component compare
Pf1N1B4_3538 -1.1 -1.4 Transcriptional regulator, AraC family compare
Pf1N1B4_4855 -1.1 -1.8 Response regulator compare
Pf1N1B4_619 -1.1 -1.8 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf1N1B4_2706 -1.1 -2.0 FIG00954871: hypothetical protein compare
Pf1N1B4_3986 -1.1 -2.6 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) compare
Pf1N1B4_4449 -1.1 -2.7 Permeases of the major facilitator superfamily compare
Pf1N1B4_4417 -1.1 -1.6 Transcriptional regulator compare
Pf1N1B4_6041 -1.1 -1.1 Carbon storage regulator compare
Pf1N1B4_4285 -1.1 -2.2 Inositol transport system sugar-binding protein compare
Pf1N1B4_74 -1.1 -1.6 hypothetical protein compare
Pf1N1B4_3973 -1.1 -2.7 ABC-type spermidine/putrescine transport system, permease component I compare
Pf1N1B4_3143 -1.1 -1.8 RecA protein compare
Pf1N1B4_3692 -1.1 -2.0 Chaperone protein HtpG compare
Pf1N1B4_5838 -1.1 -1.8 FIG00956589: hypothetical protein compare
Pf1N1B4_1749 -1.1 -1.1 Prevent host death protein, Phd antitoxin compare
Pf1N1B4_4368 -1.0 -2.6 Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_890 -1.0 -1.8 DNA recombination and repair protein RecO compare
Pf1N1B4_3717 -1.0 -2.2 Permeases of the major facilitator superfamily compare
Pf1N1B4_4669 -1.0 -1.7 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_1683 -1.0 -1.7 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_1608 -1.0 -2.0 FIG00956533: hypothetical protein compare
Pf1N1B4_5023 -1.0 -2.1 Alkylated DNA repair protein AlkB compare
Pf1N1B4_4110 -1.0 -2.8 hypothetical protein compare
Pf1N1B4_2866 -1.0 -2.3 Periplasmic hemin-binding protein compare
Pf1N1B4_3405 -1.0 -2.3 Signal transduction histidine kinase compare
Pf1N1B4_29 -1.0 -1.7 FIG00967200: hypothetical protein compare
Pf1N1B4_629 -1.0 -1.9 Queuosine Biosynthesis QueE Radical SAM compare
Pf1N1B4_3290 -1.0 -2.0 Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1) compare
Pf1N1B4_5906 -1.0 -2.2 Esterase/lipase compare
Pf1N1B4_1212 -1.0 -2.2 Predicted flavin reductase RutF in novel pyrimidine catabolism pathway compare
Pf1N1B4_758 -1.0 -2.4 Bacterioferritin compare
Pf1N1B4_5371 -1.0 -1.5 hypothetical protein compare
Pf1N1B4_776 -1.0 -2.1 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake compare
Pf1N1B4_3723 -1.0 -1.4 FIG00957314: hypothetical protein compare
Pf1N1B4_4870 -1.0 -1.2 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_127 -1.0 -1.9 FIG032225: Transcriptional regulator, LysR family compare
Pf1N1B4_4116 -1.0 -2.2 FIG011065: hypothetical protein compare
Pf1N1B4_128 -1.0 -1.9 Methylglyoxal reductase, acetol producing (EC 1.1.1.-) / 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274) compare
Pf1N1B4_3632 -1.0 -2.8 Flagellar motor rotation protein MotB compare
Pf1N1B4_821 -1.0 -4.5 Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) compare
Pf1N1B4_3297 -1.0 -2.6 Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_1226 -1.0 -3.4 FIG01201438: hypothetical protein compare
Pf1N1B4_2263 -1.0 -2.0 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf1N1B4_1332 -1.0 -1.8 Cobalt-precorrin-6 synthase, anaerobic compare
Pf1N1B4_4319 -1.0 -2.1 Phosphonate ABC transporter permease protein phnE1 (TC 3.A.1.9.1) compare
Pf1N1B4_2853 -1.0 -1.3 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
Pf1N1B4_3264 -1.0 -2.0 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_1614 -1.0 -1.3 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_2912 -1.0 -1.3 GTP-binding and nucleic acid-binding protein YchF compare
Pf1N1B4_4381 -1.0 -1.1 Transcriptional regulator, LysR family compare
Pf1N1B4_5860 -1.0 -1.5 Two-component response regulator compare
Pf1N1B4_2493 -1.0 -1.5 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_1 -1.0 -1.5 Colicin V production protein compare
Pf1N1B4_2884 -1.0 -2.9 Paraquat-inducible protein A compare
Pf1N1B4_419 -0.9 -1.2 Transcriptional regulator, TetR family compare
Pf1N1B4_3408 -0.9 -1.5 Transcriptional regulator, AraC family compare
Pf1N1B4_3809 -0.9 -2.2 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf1N1B4_4961 -0.9 -1.9 FIG00441227: hypothetical protein compare
Pf1N1B4_4734 -0.9 -2.0 Fap protein with C39 domain compare
Pf1N1B4_2549 -0.9 -4.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_3620 -0.9 -1.6 Flagellar biosynthesis protein FliR compare
Pf1N1B4_2757 -0.9 -2.2 DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31 compare
Pf1N1B4_2449 -0.9 -3.6 Probable short-chain dehydrogenase compare
Pf1N1B4_5330 -0.9 -1.2 hypothetical protein compare
Pf1N1B4_4764 -0.9 -2.5 2-ketogluconate transporter compare
Pf1N1B4_4711 -0.9 -2.5 hypothetical protein compare
Pf1N1B4_5823 -0.9 -1.0 Na(+) H(+) antiporter subunit C compare
Pf1N1B4_5864 -0.9 -1.4 Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF compare
Pf1N1B4_193 -0.9 -2.5 Transporter, LysE family compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Methionine in Pseudomonas fluorescens FW300-N1B4

For nitrogen source L-Methionine across organisms