Experiment set4IT089 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Leucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.0 -2.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1408 -3.7 -3.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_2303 -3.2 -12.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1067 -3.2 -5.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1624 -3.2 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_2547 -3.1 -2.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1831 -3.0 -9.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_350 -3.0 -5.9 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_1626 -2.9 -5.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_2880 -2.8 -11.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_2545 -2.8 -10.4 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_2549 -2.8 -7.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_1611 -2.8 -5.5 Nitrogen regulation protein NR(I) compare
Pf1N1B4_2548 -2.8 -5.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_1830 -2.8 -8.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_1565 -2.7 -3.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_3812 -2.5 -8.1 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_1315 -2.5 -7.5 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_4678 -2.5 -4.2 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf1N1B4_2282 -2.4 -8.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_58 -2.4 -5.4 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_742 -2.4 -6.4 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_2272 -2.4 -2.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_1434 -2.4 -5.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3697 -2.4 -8.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1627 -2.3 -4.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2878 -2.3 -7.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_4568 -2.2 -2.4 FIG00793915: hypothetical protein compare
Pf1N1B4_2874 -2.2 -3.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_1610 -2.2 -3.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_2010 -2.2 -5.8 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_3081 -2.1 -16.2 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_2377 -2.1 -5.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_2384 -2.1 -9.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_1906 -2.0 -3.3 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_3985 -2.0 -2.8 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_1566 -2.0 -7.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_3990 -2.0 -4.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_2879 -2.0 -5.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_2487 -2.0 -6.8 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_1625 -1.9 -4.5 FIG00956267: hypothetical protein compare
Pf1N1B4_4478 -1.9 -3.3 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_2488 -1.9 -6.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_2338 -1.9 -7.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_762 -1.9 -5.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2337 -1.8 -4.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_4481 -1.8 -2.9 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_1668 -1.8 -4.9 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_1307 -1.8 -2.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_866 -1.8 -2.2 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_2489 -1.8 -4.9 Biotin synthesis protein BioH compare
Pf1N1B4_1059 -1.8 -3.0 FIG137478: Hypothetical protein YbgI compare
Pf1N1B4_2252 -1.7 -3.6 Organosulfonate utilization protein SsuF compare
Pf1N1B4_1617 -1.7 -7.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_3506 -1.7 -5.8 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1328 -1.7 -2.8 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf1N1B4_4299 -1.7 -2.9 sensor histidine kinase compare
Pf1N1B4_875 -1.6 -2.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_2850 -1.6 -5.4 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf1N1B4_2807 -1.6 -2.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf1N1B4_2009 -1.6 -4.4 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_5665 -1.6 -3.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_3906 -1.6 -4.0 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_4870 -1.6 -2.3 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_188 -1.5 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_629 -1.5 -1.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf1N1B4_2400 -1.5 -2.6 FIG00955006: hypothetical protein compare
Pf1N1B4_2284 -1.5 -4.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_4558 -1.5 -2.8 Outer membrane lipoprotein-sorting protein compare
Pf1N1B4_2493 -1.5 -2.3 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_2011 -1.5 -6.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_4476 -1.5 -2.7 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf1N1B4_591 -1.4 -3.5 Aldose 1-epimerase compare
Pf1N1B4_1 -1.4 -2.1 Colicin V production protein compare
Pf1N1B4_974 -1.4 -2.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_683 -1.4 -3.7 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_3768 -1.4 -2.5 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_3538 -1.4 -1.8 Transcriptional regulator, AraC family compare
Pf1N1B4_2858 -1.4 -7.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1378 -1.4 -4.4 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
Pf1N1B4_3328 -1.3 -1.9 Rhodanese-like domain protein compare
Pf1N1B4_5666 -1.3 -2.5 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_2491 -1.3 -2.8 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_1317 -1.3 -2.6 Sensor histidine kinase/response regulator compare
Pf1N1B4_606 -1.3 -1.4 Iron siderophore sensor protein compare
Pf1N1B4_1782 -1.3 -2.1 hypothetical protein compare
Pf1N1B4_3670 -1.3 -3.3 probable glucosyl transferase compare
Pf1N1B4_3546 -1.3 -1.8 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_2004 -1.3 -1.9 putative membrane protein compare
Pf1N1B4_2526 -1.3 -9.0 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_2490 -1.3 -4.1 Biotin synthesis protein BioC compare
Pf1N1B4_3833 -1.3 -5.4 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_1153 -1.3 -3.0 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_4103 -1.2 -1.5 Flagellar synthesis regulator FleN compare
Pf1N1B4_2486 -1.2 -1.3 hypothetical protein compare
Pf1N1B4_4533 -1.2 -2.1 Uncharacterized protein ImpH/VasB compare
Pf1N1B4_4320 -1.2 -2.6 Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) compare
Pf1N1B4_3595 -1.2 -1.9 Flagellin protein FlaG compare
Pf1N1B4_3074 -1.2 -1.8 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_76 -1.2 -2.2 ATP binding protein compare
Pf1N1B4_2008 -1.2 -6.1 Phosphogluconate repressor HexR, RpiR family compare
Pf1N1B4_4446 -1.2 -1.5 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_5224 -1.2 -2.4 tRNA-Arg-CCT compare
Pf1N1B4_1052 -1.2 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_4759 -1.2 -1.7 Proteinase inhibitor I11, ecotin precursor compare
Pf1N1B4_678 -1.1 -5.1 Pyruvate kinase (EC 2.7.1.40) compare
Pf1N1B4_4065 -1.1 -4.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_2939 -1.1 -3.8 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf1N1B4_219 -1.1 -3.1 Acyclic terpenes utilization regulator AtuR, TetR family compare
Pf1N1B4_1381 -1.1 -6.3 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) conserved
Pf1N1B4_1380 -1.1 -6.6 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) conserved
Pf1N1B4_10 -1.1 -2.5 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) compare
Pf1N1B4_1683 -1.1 -2.0 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_72 -1.1 -1.8 Transcriptional regulator, LysR family compare
Pf1N1B4_5507 -1.1 -2.0 hypothetical protein compare
Pf1N1B4_4849 -1.1 -1.5 Various polyols ABC transporter, permease component 1 compare
Pf1N1B4_2417 -1.1 -2.1 Betaine aldehyde dehydrogenase (EC 1.2.1.8) compare
Pf1N1B4_1236 -1.1 -4.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_5737 -1.1 -2.2 Nitrate/nitrite transporter compare
Pf1N1B4_1039 -1.1 -2.6 putative membrane protein compare
Pf1N1B4_3408 -1.0 -1.6 Transcriptional regulator, AraC family compare
Pf1N1B4_3802 -1.0 -1.6 PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene compare
Pf1N1B4_27 -1.0 -2.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_4008 -1.0 -2.7 Various polyols ABC transporter, ATP-binding component compare
Pf1N1B4_1382 -1.0 -6.2 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) compare
Pf1N1B4_4219 -1.0 -1.9 FIG01074225: hypothetical protein compare
Pf1N1B4_2208 -1.0 -4.4 Polyphosphate kinase (EC 2.7.4.1) compare
Pf1N1B4_126 -1.0 -1.5 Pirin compare
Pf1N1B4_855 -1.0 -2.0 FIG021952: putative membrane protein compare
Pf1N1B4_5652 -1.0 -2.1 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf1N1B4_652 -1.0 -5.5 Sensory box histidine kinase compare
Pf1N1B4_2145 -1.0 -1.2 Translation initiation inhibitor compare
Pf1N1B4_4132 -1.0 -1.5 Mobile element protein compare
Pf1N1B4_2768 -1.0 -2.7 DNA repair protein RadA compare
Pf1N1B4_1379 -1.0 -4.7 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf1N1B4_4523 -1.0 -1.7 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf1N1B4_740 -0.9 -1.6 Leucyl-tRNA synthetase compare
Pf1N1B4_3627 -0.9 -1.2 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_795 -0.9 -2.0 hypothetical protein compare
Pf1N1B4_5622 -0.9 -2.0 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_6031 -0.9 -1.5 Ribokinase (EC 2.7.1.15) (from data) compare
Pf1N1B4_4479 -0.9 -2.0 Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) compare
Pf1N1B4_2227 -0.9 -1.7 FIG019278: hypothetical protein compare
Pf1N1B4_3703 -0.9 -2.0 NLP/P60 family protein compare
Pf1N1B4_4931 -0.9 -1.6 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_4585 -0.9 -1.7 Putative Isoquinoline 1-oxidoreductase subunit, Mll3835 protein compare
Pf1N1B4_479 -0.9 -1.8 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_3907 -0.9 -1.8 FIG00953287: hypothetical protein compare
Pf1N1B4_3632 -0.9 -2.4 Flagellar motor rotation protein MotB compare
Pf1N1B4_4509 -0.9 -1.7 Aldose 1-epimerase compare
Pf1N1B4_2283 -0.9 -1.3 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_4437 -0.9 -2.0 hypothetical protein compare
Pf1N1B4_578 -0.9 -2.1 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_3351 -0.9 -1.7 FIG00954302: hypothetical protein compare
Pf1N1B4_5799 -0.9 -2.0 Benzoate 1,2-dioxygenase beta subunit (EC 1.14.12.10) compare
Pf1N1B4_5255 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_88 -0.9 -1.8 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf1N1B4_4432 -0.9 -2.6 Dienelactone hydrolase family compare
Pf1N1B4_916 -0.9 -4.6 Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4) compare
Pf1N1B4_5274 -0.9 -2.3 hypothetical protein compare
Pf1N1B4_349 -0.8 -2.6 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf1N1B4_430 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_5720 -0.8 -1.3 hypothetical protein compare
Pf1N1B4_4486 -0.8 -1.6 Outer membrane protein (porin) compare
Pf1N1B4_1579 -0.8 -2.5 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
Pf1N1B4_4477 -0.8 -1.6 Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) compare
Pf1N1B4_5242 -0.8 -1.1 hypothetical protein compare
Pf1N1B4_4716 -0.8 -1.6 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
Pf1N1B4_4740 -0.8 -1.3 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_257 -0.8 -3.2 sensor histidine kinase/response regulator compare
Pf1N1B4_650 -0.8 -1.8 FIG001943: hypothetical protein YajQ compare
Pf1N1B4_3498 -0.8 -1.5 FIG00953240: hypothetical protein compare
Pf1N1B4_1827 -0.8 -2.5 FIG00953482: hypothetical protein compare
Pf1N1B4_522 -0.8 -1.7 HlyD family secretion protein compare
Pf1N1B4_1339 -0.8 -2.2 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
Pf1N1B4_915 -0.8 -3.5 Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4) compare
Pf1N1B4_1914 -0.8 -2.9 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf1N1B4_4992 -0.8 -2.6 Dienelactone hydrolase and related enzymes compare
Pf1N1B4_1792 -0.8 -1.9 Taurine transport ATP-binding protein TauB compare
Pf1N1B4_339 -0.8 -1.5 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_3656 -0.8 -1.3 Eukaryotic-type low-affinity urea transporter compare
Pf1N1B4_2859 -0.8 -5.9 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_3939 -0.8 -2.0 FIG00953489: hypothetical protein compare
Pf1N1B4_359 -0.8 -1.6 GGDEF domain protein compare
Pf1N1B4_2360 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_817 -0.8 -1.8 FIG00955104: hypothetical protein compare
Pf1N1B4_5321 -0.8 -2.7 hypothetical protein compare
Pf1N1B4_3372 -0.8 -1.7 FIG00962464: hypothetical protein compare
Pf1N1B4_914 -0.8 -2.7 ABC-type polar amino acid transport system, ATPase component compare
Pf1N1B4_2209 -0.8 -3.7 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_3700 -0.8 -2.1 Putative permease often clustered with de novo purine synthesis compare
Pf1N1B4_1975 -0.8 -1.3 Transcriptional regulator, AsnC family compare
Pf1N1B4_2857 -0.8 -1.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_1350 -0.8 -1.5 GCN5-related N-acetyltransferase compare
Pf1N1B4_4257 -0.8 -1.4 L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_5464 -0.7 -1.7 Cointegrate resolution protein T compare
Pf1N1B4_374 -0.7 -3.3 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) compare
Pf1N1B4_2401 -0.7 -1.6 Lipoprotein, putative compare
Pf1N1B4_3973 -0.7 -2.0 ABC-type spermidine/putrescine transport system, permease component I compare
Pf1N1B4_507 -0.7 -1.1 FIG00956448: hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Leucine in Pseudomonas fluorescens FW300-N1B4

For nitrogen source L-Leucine across organisms