Experiment set4IT088 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.0 -3.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_2208 -3.7 -5.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf1N1B4_2880 -3.6 -10.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1408 -3.6 -3.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1067 -3.4 -5.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_3697 -3.3 -8.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1624 -3.2 -6.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_2548 -3.2 -5.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2545 -3.2 -11.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_2303 -3.2 -12.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1830 -3.2 -8.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2547 -3.2 -2.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_847 -3.1 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_1611 -3.0 -5.6 Nitrogen regulation protein NR(I) compare
Pf1N1B4_1831 -2.9 -9.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_15 -2.9 -3.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2338 -2.9 -5.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1610 -2.8 -3.8 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_4476 -2.8 -3.2 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf1N1B4_1434 -2.8 -6.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1626 -2.8 -6.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_350 -2.8 -7.2 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_1315 -2.7 -7.7 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_2384 -2.7 -10.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_1307 -2.7 -3.1 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_1565 -2.7 -4.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_742 -2.7 -6.3 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_2010 -2.6 -6.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_2549 -2.6 -8.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2878 -2.5 -7.3 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_4678 -2.4 -4.8 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf1N1B4_2879 -2.4 -5.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_3821 -2.4 -5.3 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf1N1B4_2850 -2.4 -5.6 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf1N1B4_2282 -2.4 -8.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3081 -2.4 -17.1 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_5666 -2.4 -3.6 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_2487 -2.4 -7.4 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_2526 -2.3 -13.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_4299 -2.3 -3.5 sensor histidine kinase compare
Pf1N1B4_2858 -2.3 -8.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_12 -2.3 -6.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_2337 -2.3 -4.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2724 -2.2 -6.9 Transcriptional regulator, AsnC family compare
Pf1N1B4_3812 -2.2 -8.4 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_5665 -2.2 -4.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2491 -2.2 -4.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_1627 -2.1 -4.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2272 -2.1 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_2488 -2.1 -6.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_58 -2.1 -5.5 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_1039 -2.1 -3.7 putative membrane protein compare
Pf1N1B4_2009 -2.1 -4.4 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_762 -2.1 -5.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_3833 -2.1 -7.6 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_1625 -2.0 -3.7 FIG00956267: hypothetical protein compare
Pf1N1B4_3506 -2.0 -5.9 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_3325 -2.0 -1.7 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_3906 -2.0 -4.6 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_3819 -2.0 -3.9 Methylisocitrate lyase (EC 4.1.3.30) compare
Pf1N1B4_578 -2.0 -3.6 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_2490 -2.0 -5.4 Biotin synthesis protein BioC compare
Pf1N1B4_2011 -1.9 -7.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_3446 -1.9 -2.1 Putative GTPases (G3E family) compare
Pf1N1B4_2283 -1.9 -2.1 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_1668 -1.8 -4.8 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_1566 -1.8 -7.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_4931 -1.8 -2.8 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_2695 -1.8 -2.4 Rare lipoprotein A precursor compare
Pf1N1B4_556 -1.8 -3.8 Gluconate permease compare
Pf1N1B4_5724 -1.7 -3.1 High-affinity iron permease compare
Pf1N1B4_2493 -1.7 -2.7 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_2377 -1.7 -5.6 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_3985 -1.7 -2.6 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_1317 -1.7 -3.2 Sensor histidine kinase/response regulator compare
Pf1N1B4_4477 -1.7 -2.9 Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) compare
Pf1N1B4_4669 -1.6 -2.5 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_2401 -1.6 -2.8 Lipoprotein, putative compare
Pf1N1B4_652 -1.6 -7.9 Sensory box histidine kinase compare
Pf1N1B4_4065 -1.6 -6.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_4478 -1.6 -2.6 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_1617 -1.6 -6.4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_2853 -1.6 -1.9 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
Pf1N1B4_2177 -1.5 -1.2 FIG00953342: hypothetical protein compare
Pf1N1B4_2859 -1.5 -10.3 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_2706 -1.5 -2.2 FIG00954871: hypothetical protein compare
Pf1N1B4_3849 -1.5 -3.6 Transcriptional regulator, GntR family compare
Pf1N1B4_2854 -1.5 -3.5 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf1N1B4_1906 -1.5 -3.6 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_5699 -1.5 -2.1 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_27 -1.5 -3.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_875 -1.4 -2.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_5906 -1.4 -3.2 Esterase/lipase compare
Pf1N1B4_4783 -1.4 -3.2 Transcriptional regulator, AraC family compare
Pf1N1B4_219 -1.4 -3.8 Acyclic terpenes utilization regulator AtuR, TetR family compare
Pf1N1B4_2008 -1.4 -6.7 Phosphogluconate repressor HexR, RpiR family compare
Pf1N1B4_4446 -1.4 -2.2 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_5624 -1.4 -2.8 Lipase precursor (EC 3.1.1.3) compare
Pf1N1B4_5834 -1.4 -2.3 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) compare
Pf1N1B4_5777 -1.4 -2.9 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf1N1B4_2874 -1.4 -2.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_866 -1.4 -1.7 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_6037 -1.3 -2.5 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_74 -1.3 -2.4 hypothetical protein compare
Pf1N1B4_3820 -1.3 -5.9 2-methylcitrate synthase (EC 2.3.3.5) compare
Pf1N1B4_5451 -1.3 -2.2 hypothetical protein compare
Pf1N1B4_5255 -1.3 -2.5 hypothetical protein compare
Pf1N1B4_678 -1.3 -5.8 Pyruvate kinase (EC 2.7.1.40) compare
Pf1N1B4_2860 -1.3 -4.8 FIG00954153: hypothetical protein compare
Pf1N1B4_1653 -1.3 -5.1 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_4480 -1.3 -2.6 Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) compare
Pf1N1B4_5645 -1.3 -2.5 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) compare
Pf1N1B4_4897 -1.2 -2.2 Transcriptional regulator, LysR family compare
Pf1N1B4_4195 -1.2 -3.1 Transcriptional regulator, TetR family compare
Pf1N1B4_4481 -1.2 -2.2 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_4257 -1.2 -2.0 L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_3703 -1.2 -2.4 NLP/P60 family protein compare
Pf1N1B4_1391 -1.2 -3.9 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf1N1B4_4759 -1.2 -1.8 Proteinase inhibitor I11, ecotin precursor compare
Pf1N1B4_3595 -1.2 -1.9 Flagellin protein FlaG compare
Pf1N1B4_2339 -1.2 -2.1 COG1872 compare
Pf1N1B4_1975 -1.2 -1.8 Transcriptional regulator, AsnC family compare
Pf1N1B4_591 -1.2 -3.9 Aldose 1-epimerase compare
Pf1N1B4_683 -1.1 -3.3 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_4761 -1.1 -1.8 hypothetical protein compare
Pf1N1B4_1561 -1.1 -2.7 FIG00954300: hypothetical protein compare
Pf1N1B4_349 -1.1 -3.3 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf1N1B4_4602 -1.1 -1.6 Transcriptional regulators, LysR family compare
Pf1N1B4_1234 -1.1 -3.1 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_4972 -1.1 -2.1 CELL PROCESSES; Adaptation; adaptations, atypical conditions compare
Pf1N1B4_1392 -1.1 -5.0 Protein containing domains DUF404, DUF407, DUF403 compare
Pf1N1B4_275 -1.1 -1.5 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_1683 -1.1 -2.0 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_5023 -1.1 -2.8 Alkylated DNA repair protein AlkB compare
Pf1N1B4_4436 -1.1 -2.5 Glutaminase (EC 3.5.1.2) compare
Pf1N1B4_2885 -1.1 -3.9 Paraquat-inducible protein A compare
Pf1N1B4_596 -1.1 -2.9 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf1N1B4_4787 -1.1 -2.7 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Pf1N1B4_915 -1.1 -4.3 Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4) compare
Pf1N1B4_5745 -1.0 -2.2 FIG139928: Putative protease compare
Pf1N1B4_5483 -1.0 -1.8 hypothetical protein compare
Pf1N1B4_2527 -1.0 -5.8 ApaG protein compare
Pf1N1B4_765 -1.0 -2.0 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_2969 -1.0 -6.8 ATPase, AFG1 family compare
Pf1N1B4_5591 -1.0 -1.7 Vanillin dehydrogenase (Hydroxybenzaldehyde dehydrogenase) (EC 1.2.1.28) compare
Pf1N1B4_1126 -1.0 -2.3 Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) compare
Pf1N1B4_4596 -1.0 -2.0 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
Pf1N1B4_76 -1.0 -2.1 ATP binding protein compare
Pf1N1B4_917 -1.0 -4.9 Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4) compare
Pf1N1B4_4494 -1.0 -2.4 hypothetical protein compare
Pf1N1B4_3290 -1.0 -2.3 Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1) compare
Pf1N1B4_1153 -1.0 -2.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_2105 -1.0 -1.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_2123 -1.0 -4.0 hypothetical protein compare
Pf1N1B4_2225 -1.0 -6.0 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_4990 -1.0 -1.6 FIG018171: hypothetical protein of Cupin superfamily compare
Pf1N1B4_606 -1.0 -1.4 Iron siderophore sensor protein compare
Pf1N1B4_1095 -1.0 -6.0 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf1N1B4_3141 -0.9 -1.5 FIG00959768: hypothetical protein compare
Pf1N1B4_564 -0.9 -2.1 ABC-type phosphate/phosphonate transport system, periplasmic component compare
Pf1N1B4_904 -0.9 -1.6 DNA-binding protein HU-beta compare
Pf1N1B4_4107 -0.9 -1.8 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_257 -0.9 -3.7 sensor histidine kinase/response regulator compare
Pf1N1B4_1568 -0.9 -2.6 Twin-arginine translocation protein TatB compare
Pf1N1B4_3367 -0.9 -2.8 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf1N1B4_4417 -0.9 -1.6 Transcriptional regulator compare
Pf1N1B4_4764 -0.9 -2.5 2-ketogluconate transporter compare
Pf1N1B4_1914 -0.9 -3.1 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf1N1B4_3168 -0.9 -2.0 AmpG permease compare
Pf1N1B4_4301 -0.9 -2.3 hypothetical protein compare
Pf1N1B4_2682 -0.9 -1.4 Antiholin-like protein LrgA compare
Pf1N1B4_647 -0.9 -4.4 hypothetical protein compare
Pf1N1B4_2431 -0.9 -2.5 L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) compare
Pf1N1B4_2209 -0.9 -4.2 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_626 -0.9 -4.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf1N1B4_4368 -0.9 -2.1 Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_3711 -0.9 -3.2 Cobyric acid synthase (EC 6.3.5.10) compare
Pf1N1B4_5838 -0.9 -1.7 FIG00956589: hypothetical protein compare
Pf1N1B4_3900 -0.9 -2.3 Universal stress protein family COG0589 compare
Pf1N1B4_648 -0.9 -8.0 Outer membrane porin, OprD family compare
Pf1N1B4_3503 -0.9 -2.9 Two-component response regulator PfeR, enterobactin compare
Pf1N1B4_4437 -0.9 -2.0 hypothetical protein compare
Pf1N1B4_1246 -0.9 -1.2 FIG00954047: hypothetical protein compare
Pf1N1B4_4390 -0.9 -1.7 Transcriptional regulator, LacI family compare
Pf1N1B4_5737 -0.9 -2.0 Nitrate/nitrite transporter compare
Pf1N1B4_373 -0.9 -2.0 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC compare
Pf1N1B4_2485 -0.9 -1.2 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy compare
Pf1N1B4_3709 -0.9 -2.2 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf1N1B4_3484 -0.9 -3.1 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf1N1B4_3368 -0.9 -1.4 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_1378 -0.8 -3.1 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
Pf1N1B4_1472 -0.8 -1.2 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_2734 -0.8 -1.3 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_5663 -0.8 -1.4 Periplasmic sugar-binding domain protein compare
Pf1N1B4_29 -0.8 -1.7 FIG00967200: hypothetical protein compare
Pf1N1B4_974 -0.8 -2.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_1402 -0.8 -2.2 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) compare
Pf1N1B4_3152 -0.8 -3.2 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_4636 -0.8 -1.4 TPR domain protein in aerotolerance operon compare
Pf1N1B4_3217 -0.8 -2.1 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N1B4 in nitrogen source experiments

For nitrogen source L-Isoleucine across organisms