Experiment set4IT088 for Klebsiella michiganensis M5al

Compare to:

D-Xylose carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS00805 -7.9 -5.4 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01655 -7.4 -7.2 homoserine O-succinyltransferase compare
BWI76_RS18930 -7.0 -6.8 histidinol-phosphate transaminase compare
BWI76_RS04675 -6.2 -7.3 3-isopropylmalate dehydrogenase compare
BWI76_RS00850 -6.1 -5.9 acetylglutamate kinase compare
BWI76_RS11850 -6.1 -10.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS18950 -5.9 -5.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04470 -5.8 -8.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS20895 -5.7 -5.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS09755 -5.7 -6.8 phosphoserine transaminase compare
BWI76_RS05835 -5.7 -3.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS04160 -5.7 -8.6 phosphoserine phosphatase compare
BWI76_RS00855 -5.5 -9.2 argininosuccinate lyase compare
BWI76_RS04250 -5.5 -8.4 homoserine kinase compare
BWI76_RS11965 -5.5 -5.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23920 -5.4 -6.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00785 -5.4 -6.4 cystathionine gamma-synthase compare
BWI76_RS00980 -5.4 -10.3 PLP-dependent threonine dehydratase compare
BWI76_RS04255 -5.1 -11.3 threonine synthase compare
BWI76_RS24285 -5.0 -9.0 cystathionine beta-lyase compare
BWI76_RS18935 -5.0 -9.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00990 -5.0 -8.2 ketol-acid reductoisomerase compare
BWI76_RS04645 -5.0 -7.6 3-dehydroquinase compare
BWI76_RS23220 -5.0 -8.5 amino-acid N-acetyltransferase compare
BWI76_RS04665 -4.9 -18.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04465 -4.9 -5.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS22755 -4.9 -9.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04245 -4.8 -15.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS27045 -4.8 -7.9 XylR family transcriptional regulator conserved
BWI76_RS04670 -4.8 -10.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS26085 -4.8 -3.2 3-dehydroquinate synthase compare
BWI76_RS02995 -4.7 -8.8 aspartate carbamoyltransferase compare
BWI76_RS20355 -4.7 -4.3 colicin V production protein compare
BWI76_RS11845 -4.6 -2.0 tryptophan synthase subunit beta compare
BWI76_RS22690 -4.6 -4.0 adenylyl-sulfate kinase compare
BWI76_RS07070 -4.6 -6.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20350 -4.6 -5.7 amidophosphoribosyltransferase compare
BWI76_RS10990 -4.5 -3.1 dihydroorotase compare
BWI76_RS01615 -4.5 -11.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04680 -4.5 -12.1 2-isopropylmalate synthase compare
BWI76_RS09760 -4.5 -5.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS21475 -4.5 -7.6 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18955 -4.5 -4.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS11860 -4.4 -7.0 anthranilate synthase component I compare
BWI76_RS20965 -4.4 -3.8 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00835 -4.4 -14.6 phosphoenolpyruvate carboxylase compare
BWI76_RS25115 -4.3 -9.6 argininosuccinate synthase compare
BWI76_RS18920 -4.3 -4.2 ATP phosphoribosyltransferase compare
BWI76_RS04685 -4.3 -11.6 putative leucine operon leader peptide compare
BWI76_RS27385 -4.3 -8.6 orotate phosphoribosyltransferase compare
BWI76_RS11840 -4.3 -5.8 tryptophan synthase subunit alpha compare
BWI76_RS23360 -4.2 -4.7 diaminopimelate decarboxylase compare
BWI76_RS03010 -4.0 -9.3 ornithine carbamoyltransferase compare
BWI76_RS00975 -4.0 -10.0 dihydroxy-acid dehydratase compare
BWI76_RS00985 -3.9 -7.9 transcriptional regulator IlvY compare
BWI76_RS18940 -3.9 -6.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS09670 -3.9 -4.7 recombination factor protein RarA compare
BWI76_RS04240 -3.8 -2.8 thr operon leader peptide compare
BWI76_RS01210 -3.8 -2.6 tyrosine recombinase XerC compare
BWI76_RS00845 -3.7 -8.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS18925 -3.7 -5.2 histidinol dehydrogenase compare
BWI76_RS22765 -3.7 -12.9 sulfite reductase subunit alpha compare
BWI76_RS05015 -3.7 -4.3 transcriptional regulator compare
BWI76_RS27025 -3.7 -14.4 Xylose isomerase (EC 5.3.1.5) (from data) conserved
BWI76_RS21265 -3.6 -11.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS08385 -3.6 -5.4 citrate (Si)-synthase compare
BWI76_RS22805 -3.5 -11.3 GTP diphosphokinase compare
BWI76_RS09910 -3.5 -17.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS27390 -3.5 -5.2 ribonuclease PH compare
BWI76_RS05840 -3.5 -6.2 glutamate 5-kinase compare
BWI76_RS11855 -3.4 -4.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01610 -3.4 -8.7 phosphoribosylamine--glycine ligase compare
BWI76_RS20435 -3.4 -2.1 chorismate synthase compare
BWI76_RS15825 -3.3 -3.0 hypothetical protein compare
BWI76_RS21465 -3.2 -5.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS07065 -3.2 -5.8 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23365 -3.1 -2.8 LysR family transcriptional regulator compare
BWI76_RS22760 -3.1 -6.8 sulfite reductase subunit beta compare
BWI76_RS27430 -3.1 -2.0 (p)ppGpp synthetase compare
BWI76_RS00965 -3.1 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS25960 -3.0 -5.0 NUDIX hydrolase compare
BWI76_RS05200 -3.0 -3.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS23240 -2.9 -3.9 exonuclease V subunit gamma compare
BWI76_RS00400 -2.7 -1.8 glutamine synthetase compare
BWI76_RS11435 -2.7 -2.2 hypothetical protein compare
BWI76_RS25645 -2.5 -7.7 shikimate dehydrogenase compare
BWI76_RS26075 -2.3 -3.8 DNA adenine methylase compare
BWI76_RS27020 -2.3 -6.5 Xylulose kinase (EC 2.7.1.17) (from data) conserved
BWI76_RS17720 -2.2 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS02530 -2.2 -2.9 tRNA dimethylallyltransferase compare
BWI76_RS20440 -2.2 -1.8 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS00345 -2.1 -4.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS00390 -2.0 -6.1 two-component system sensor histidine kinase NtrB compare
BWI76_RS06185 -2.0 -9.5 shikimate kinase II compare
BWI76_RS11900 -2.0 -1.9 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS23230 -1.9 -3.2 exodeoxyribonuclease V subunit beta compare
BWI76_RS23480 -1.9 -10.5 EAL domain-containing protein compare
BWI76_RS15835 -1.9 -1.6 hypothetical protein compare
BWI76_RS04270 -1.9 -3.1 transaldolase compare
BWI76_RS09660 -1.8 -2.2 DNA translocase FtsK compare
BWI76_RS26455 -1.7 -4.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS09645 -1.7 -1.7 thioredoxin-disulfide reductase compare
BWI76_RS13980 -1.7 -2.0 hypothetical protein compare
BWI76_RS20750 -1.7 -1.6 carboxysome structural protein EutK compare
BWI76_RS02735 -1.6 -3.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS26055 -1.6 -6.5 siroheme synthase compare
BWI76_RS26460 -1.5 -4.6 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS07185 -1.5 -2.6 hypothetical protein compare
BWI76_RS26000 -1.5 -6.0 aspartate aminotransferase family protein compare
BWI76_RS01350 -1.5 -1.7 NAD(P)H-flavin reductase compare
BWI76_RS17390 -1.5 -2.8 DsrE family protein compare
BWI76_RS26570 -1.4 -2.9 anion permease compare
BWI76_RS04510 -1.4 -1.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS22420 -1.4 -3.1 LacI family transcriptional regulator compare
BWI76_RS02180 -1.4 -1.7 hypothetical protein compare
BWI76_RS20640 -1.3 -4.4 cysteine synthase A compare
BWI76_RS22950 -1.3 -2.8 membrane protein compare
BWI76_RS17945 -1.3 -1.6 hypothetical protein compare
BWI76_RS02990 -1.3 -3.7 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS25315 -1.3 -8.6 glutamate synthase large subunit compare
BWI76_RS19585 -1.3 -2.6 gentisate 1,2-dioxygenase compare
BWI76_RS13095 -1.3 -2.3 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS06525 -1.2 -4.4 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS06530 -1.2 -4.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS12470 -1.2 -1.8 thiosulfate sulfurtransferase PspE compare
BWI76_RS00180 -1.2 -1.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS25285 -1.2 -1.0 HPr family phosphocarrier protein compare
BWI76_RS19325 -1.2 -1.8 mandelate racemase compare
BWI76_RS16760 -1.2 -3.3 lipase compare
BWI76_RS19935 -1.2 -1.7 hypothetical protein compare
BWI76_RS16480 -1.2 -4.1 lactoylglutathione lyase compare
BWI76_RS00385 -1.2 -5.4 nitrogen assimilation regulatory protein compare
BWI76_RS20650 -1.1 -1.3 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS15060 -1.1 -3.0 MarR family transcriptional regulator compare
BWI76_RS00355 -1.1 -2.1 DNA polymerase I compare
BWI76_RS21070 -1.1 -2.2 outer membrane protein assembly factor BamB compare
BWI76_RS11010 -1.1 -2.3 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS24900 -1.1 -1.5 DeoR family transcriptional regulator compare
BWI76_RS18385 -1.1 -1.4 hypothetical protein compare
BWI76_RS15920 -1.1 -1.4 hypothetical protein compare
BWI76_RS03415 -1.1 -5.0 LacI family transcriptional regulator compare
BWI76_RS16275 -1.0 -2.2 fumarate hydratase FumA compare
BWI76_RS25425 -1.0 -1.4 arginine repressor compare
BWI76_RS03080 -1.0 -1.7 (Fe-S)-cluster assembly protein compare
BWI76_RS25320 -1.0 -4.4 glutamate synthase compare
BWI76_RS18905 -1.0 -2.3 putrescine/spermidine ABC transporter compare
BWI76_RS12150 -1.0 -2.7 DNA damage-inducible protein I compare
BWI76_RS16150 -1.0 -1.6 IclR family transcriptional regulator compare
BWI76_RS21480 -1.0 -3.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS23305 -1.0 -2.3 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS25065 -1.0 -2.2 polyribonucleotide nucleotidyltransferase compare
BWI76_RS04360 -1.0 -2.6 ribonucleoside hydrolase RihC compare
BWI76_RS08730 -0.9 -2.3 histidine utilization repressor compare
BWI76_RS25225 -0.9 -3.2 ABC transporter permease compare
BWI76_RS00960 -0.9 -3.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS20360 -0.9 -1.0 cell division protein DedD compare
BWI76_RS13250 -0.9 -1.1 cytochrome b561 compare
BWI76_RS27075 -0.9 -3.9 IclR family transcriptional regulator compare
BWI76_RS09960 -0.9 -1.8 Lon protease compare
BWI76_RS16795 -0.9 -2.1 amino acid ABC transporter ATPase compare
BWI76_RS00875 -0.9 -3.9 DNA-binding transcriptional regulator FabR compare
BWI76_RS24110 -0.9 -1.3 YggU family protein compare
BWI76_RS20720 -0.9 -1.5 hypothetical protein compare
BWI76_RS08530 -0.9 -2.0 protein TolA compare
BWI76_RS22125 -0.9 -1.8 membrane protein compare
BWI76_RS27435 -0.9 -3.3 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS03225 -0.8 -4.1 transcriptional regulator compare
BWI76_RS21310 -0.8 -0.9 DNA repair protein RecO compare
BWI76_RS11155 -0.8 -1.3 penicillin-binding protein activator LpoB compare
BWI76_RS16360 -0.8 -1.3 electron transport complex subunit RsxB compare
BWI76_RS14540 -0.8 -2.5 yersiniabactin biosynthetic protein YbtU compare
BWI76_RS20475 -0.8 -2.3 phospholipid-binding lipoprotein MlaA compare
BWI76_RS24025 -0.8 -4.0 agmatinase compare
BWI76_RS22240 -0.8 -3.0 transcriptional regulator compare
BWI76_RS05120 -0.8 -5.4 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS26775 -0.8 -3.3 endo-1,4-D-glucanase compare
BWI76_RS21000 -0.8 -3.1 exopolyphosphatase compare
BWI76_RS06830 -0.8 -2.3 recombination protein RecR compare
BWI76_RS09615 -0.8 -2.1 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS21235 -0.8 -1.2 hypothetical protein compare
BWI76_RS12860 -0.8 -1.4 hypothetical protein compare
BWI76_RS25505 -0.8 -4.7 RNase E specificity factor CsrD compare
BWI76_RS10740 -0.8 -3.1 NAD(P)H:quinone oxidoreductase compare
BWI76_RS24810 -0.8 -2.4 hypothetical protein compare
BWI76_RS21565 -0.8 -1.1 outer membrane protein assembly factor BamE compare
BWI76_RS16895 -0.8 -1.4 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS06190 -0.8 -1.6 hypothetical protein compare
BWI76_RS10040 -0.8 -1.3 heat-shock protein HspQ compare
BWI76_RS19775 -0.8 -1.3 phage resistance protein compare
BWI76_RS24605 -0.8 -4.6 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS25060 -0.8 -1.6 lipoprotein NlpI compare
BWI76_RS20785 -0.8 -1.0 ethanolamine utilization protein EutJ compare
BWI76_RS14050 -0.8 -2.0 AP endonuclease, family 2 compare
BWI76_RS23735 -0.8 -1.9 sugar diacid utilization regulator compare
BWI76_RS11895 -0.8 -1.9 AraC family transcriptional regulator compare
BWI76_RS17155 -0.8 -1.5 hypothetical protein compare
BWI76_RS16445 -0.7 -2.5 auxiliary transporter membrane fusion protein compare
BWI76_RS09470 -0.7 -1.8 putrescine ABC transporter permease compare
BWI76_RS16810 -0.7 -3.2 RpiR family transcriptional regulator compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source D-Xylose in Klebsiella michiganensis M5al

For carbon source D-Xylose across organisms