Experiment set4IT087 for Klebsiella michiganensis M5al

Compare to:

L-Sorbose carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS00805 -7.7 -5.3 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18925 -7.1 -4.9 histidinol dehydrogenase compare
BWI76_RS04675 -7.1 -4.9 3-isopropylmalate dehydrogenase compare
BWI76_RS18930 -7.1 -6.5 histidinol-phosphate transaminase compare
BWI76_RS18950 -7.0 -4.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS18940 -6.8 -4.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04250 -6.7 -6.5 homoserine kinase compare
BWI76_RS20895 -6.7 -4.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS20995 -6.6 -4.6 RNA degradosome polyphosphate kinase compare
BWI76_RS04255 -6.6 -7.8 threonine synthase compare
BWI76_RS00855 -6.3 -6.2 argininosuccinate lyase compare
BWI76_RS23220 -6.3 -6.2 amino-acid N-acetyltransferase compare
BWI76_RS11965 -6.3 -5.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS22805 -6.2 -8.5 GTP diphosphokinase compare
BWI76_RS04470 -6.2 -7.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS20350 -6.1 -5.8 amidophosphoribosyltransferase compare
BWI76_RS04465 -6.1 -4.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09755 -6.1 -7.2 phosphoserine transaminase compare
BWI76_RS11850 -6.0 -10.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26190 -6.0 -5.8 glycerol-3-phosphate dehydrogenase compare
BWI76_RS01655 -6.0 -8.1 homoserine O-succinyltransferase compare
BWI76_RS11860 -6.0 -8.1 anthranilate synthase component I compare
BWI76_RS09655 -5.8 -5.6 leucine-responsive regulatory protein compare
BWI76_RS07065 -5.8 -7.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS05835 -5.8 -3.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS17065 -5.7 -10.3 phosphoenolpyruvate synthase compare
BWI76_RS18920 -5.7 -3.9 ATP phosphoribosyltransferase compare
BWI76_RS00850 -5.7 -9.9 acetylglutamate kinase compare
BWI76_RS05015 -5.6 -3.9 transcriptional regulator compare
BWI76_RS26455 -5.6 -3.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS00835 -5.5 -13.3 phosphoenolpyruvate carboxylase compare
BWI76_RS18935 -5.5 -8.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04510 -5.4 -3.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS00785 -5.4 -6.5 cystathionine gamma-synthase compare
BWI76_RS00240 -5.4 -3.7 FMN-binding protein MioC compare
BWI76_RS07070 -5.2 -7.2 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS15955 -5.2 -7.9 transcriptional regulator compare
BWI76_RS00990 -5.2 -7.9 ketol-acid reductoisomerase compare
BWI76_RS20355 -5.2 -5.0 colicin V production protein compare
BWI76_RS02995 -5.1 -8.0 aspartate carbamoyltransferase compare
BWI76_RS04665 -5.0 -17.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS27385 -5.0 -6.9 orotate phosphoribosyltransferase compare
BWI76_RS23920 -5.0 -6.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS21475 -5.0 -7.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00985 -5.0 -6.8 transcriptional regulator IlvY compare
BWI76_RS09760 -5.0 -4.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS09910 -5.0 -19.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04645 -4.9 -5.2 3-dehydroquinase compare
BWI76_RS22765 -4.9 -14.5 sulfite reductase subunit alpha compare
BWI76_RS24285 -4.9 -7.5 cystathionine beta-lyase compare
BWI76_RS21265 -4.9 -14.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS17720 -4.8 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04670 -4.8 -10.7 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01615 -4.8 -10.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00980 -4.8 -10.3 PLP-dependent threonine dehydratase compare
BWI76_RS26460 -4.7 -5.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS26085 -4.7 -3.2 3-dehydroquinate synthase compare
BWI76_RS09645 -4.7 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS27515 -4.6 -15.2 glycerol kinase compare
BWI76_RS09640 -4.5 -6.0 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS01730 -4.5 -17.0 PTS mannose/fructose/sorbose transporter subunit IIC compare
BWI76_RS04245 -4.4 -14.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04705 -4.4 -6.6 DNA-binding transcriptional regulator FruR compare
BWI76_RS00845 -4.4 -7.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04680 -4.3 -12.8 2-isopropylmalate synthase compare
BWI76_RS04685 -4.3 -10.7 putative leucine operon leader peptide compare
BWI76_RS04160 -4.3 -9.2 phosphoserine phosphatase compare
BWI76_RS08385 -4.3 -5.1 citrate (Si)-synthase compare
BWI76_RS22755 -4.3 -6.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11845 -4.3 -3.2 tryptophan synthase subunit beta compare
BWI76_RS27510 -4.3 -6.5 aquaporin compare
BWI76_RS18955 -4.3 -6.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS22760 -4.1 -8.6 sulfite reductase subunit beta compare
BWI76_RS01720 -4.1 -6.2 L-sorbose 1-phosphate reductase (EC 1.1.1.-) (from data) compare
BWI76_RS00140 -4.1 -1.7 phosphate transport system regulator PhoU compare
BWI76_RS23365 -4.1 -5.4 LysR family transcriptional regulator compare
BWI76_RS01750 -4.0 -12.0 Cro/Cl family transcriptional regulator compare
BWI76_RS26685 -4.0 -6.3 glutathione-disulfide reductase compare
BWI76_RS26075 -4.0 -4.7 DNA adenine methylase compare
BWI76_RS11840 -4.0 -3.5 tryptophan synthase subunit alpha compare
BWI76_RS00975 -3.9 -7.6 dihydroxy-acid dehydratase compare
BWI76_RS20965 -3.9 -5.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS25115 -3.9 -4.1 argininosuccinate synthase compare
BWI76_RS03080 -3.8 -4.7 (Fe-S)-cluster assembly protein compare
BWI76_RS04240 -3.8 -2.5 thr operon leader peptide compare
BWI76_RS23240 -3.8 -2.6 exonuclease V subunit gamma compare
BWI76_RS03010 -3.7 -6.3 ornithine carbamoyltransferase compare
BWI76_RS11855 -3.7 -8.1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS22690 -3.6 -3.9 adenylyl-sulfate kinase compare
BWI76_RS25070 -3.6 -2.1 hypothetical protein compare
BWI76_RS10990 -3.6 -2.3 dihydroorotase compare
BWI76_RS23360 -3.6 -5.3 diaminopimelate decarboxylase compare
BWI76_RS27390 -3.5 -5.2 ribonuclease PH compare
BWI76_RS05840 -3.4 -5.6 glutamate 5-kinase compare
BWI76_RS19730 -3.4 -2.6 1-phosphofructokinase compare
BWI76_RS01350 -3.4 -1.9 NAD(P)H-flavin reductase compare
BWI76_RS05200 -3.4 -3.2 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09650 -3.3 -6.8 hypothetical protein compare
BWI76_RS21465 -3.3 -5.1 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01210 -3.2 -2.1 tyrosine recombinase XerC compare
BWI76_RS17975 -3.2 -6.3 tail-specific protease compare
BWI76_RS01610 -3.2 -4.7 phosphoribosylamine--glycine ligase compare
BWI76_RS01745 -3.1 -12.1 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data) compare
BWI76_RS01185 -3.1 -2.1 adenylate cyclase compare
BWI76_RS04270 -3.0 -5.3 transaldolase compare
BWI76_RS23330 -3.0 -4.3 transcriptional regulator GalR compare
BWI76_RS08405 -2.9 -3.9 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS19690 -2.9 -3.7 LysR family transcriptional regulator compare
BWI76_RS25645 -2.9 -9.1 shikimate dehydrogenase compare
BWI76_RS01725 -2.9 -6.0 PTS mannose/fructose/sorbose family transporter subunit IID compare
BWI76_RS08395 -2.8 -2.5 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS27075 -2.8 -7.0 IclR family transcriptional regulator compare
BWI76_RS20435 -2.8 -2.3 chorismate synthase compare
BWI76_RS01800 -2.8 -3.7 glucose-6-phosphate isomerase compare
BWI76_RS25335 -2.8 -3.3 stringent starvation protein A compare
BWI76_RS02735 -2.7 -4.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS23230 -2.7 -2.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS01740 -2.7 -6.1 PTS enzyme IIAB, mannose-specific compare
BWI76_RS01070 -2.7 -8.4 thiol reductase thioredoxin compare
BWI76_RS25065 -2.6 -2.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00400 -2.6 -1.7 glutamine synthetase compare
BWI76_RS08500 -2.5 -4.8 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS01735 -2.5 -14.5 PTS mannose/fructose/sorbose family transporter subunit IIB compare
BWI76_RS26055 -2.5 -8.3 siroheme synthase compare
BWI76_RS09660 -2.3 -2.6 DNA translocase FtsK compare
BWI76_RS08495 -2.3 -5.3 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS16200 -2.2 -3.2 NAD(P) transhydrogenase subunit beta compare
BWI76_RS20640 -2.2 -5.4 cysteine synthase A compare
BWI76_RS25320 -2.2 -6.6 glutamate synthase compare
BWI76_RS06525 -2.1 -6.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS25960 -2.0 -3.4 NUDIX hydrolase compare
BWI76_RS02815 -2.0 -2.9 fructose-bisphosphatase class I compare
BWI76_RS09625 -2.0 -2.4 hypothetical protein compare
BWI76_RS00345 -2.0 -3.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS26000 -1.9 -4.9 aspartate aminotransferase family protein compare
BWI76_RS25315 -1.9 -9.9 glutamate synthase large subunit compare
BWI76_RS01200 -1.9 -2.5 diaminopimelate epimerase compare
BWI76_RS19025 -1.9 -9.9 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS02410 -1.9 -2.0 EF-P beta-lysylation protein EpmB compare
BWI76_RS16205 -1.9 -5.9 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS22120 -1.9 -6.5 glutamate--cysteine ligase compare
BWI76_RS00390 -1.9 -5.4 two-component system sensor histidine kinase NtrB compare
BWI76_RS07305 -1.8 -8.0 sucrose operon repressor compare
BWI76_RS26570 -1.8 -3.7 anion permease compare
BWI76_RS22230 -1.8 -5.9 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data) compare
BWI76_RS24075 -1.8 -3.7 glutathione synthase compare
BWI76_RS20970 -1.8 -1.8 phosphoribosylglycinamide formyltransferase compare
BWI76_RS20440 -1.7 -1.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS04620 -1.7 -7.5 transcriptional regulator SgrR compare
BWI76_RS09635 -1.7 -3.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS01110 -1.7 -5.8 TDP-fucosamine acetyltransferase compare
BWI76_RS21480 -1.7 -3.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS07465 -1.7 -2.3 TetR family transcriptional regulator compare
BWI76_RS26405 -1.7 -1.3 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS09065 -1.6 -4.2 sugar phosphatase SupH compare
BWI76_RS08620 -1.6 -4.2 galactose-1-phosphate uridylyltransferase compare
BWI76_RS24885 -1.6 -1.7 PTS galactitol transporter subunit IIB compare
BWI76_RS01115 -1.6 -3.6 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS00180 -1.6 -1.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS02985 -1.6 -4.2 reactive intermediate/imine deaminase compare
BWI76_RS04525 -1.6 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS09615 -1.6 -2.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS17980 -1.6 -4.5 RNA chaperone ProQ compare
BWI76_RS08210 -1.5 -2.1 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS15825 -1.5 -2.1 hypothetical protein compare
BWI76_RS21345 -1.5 -2.4 sigma-E factor regulatory protein RseB compare
BWI76_RS19375 -1.4 -2.3 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS00965 -1.4 -1.2 acetolactate synthase 2 small subunit compare
BWI76_RS26470 -1.4 -4.0 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS00380 -1.4 -7.0 oxygen-independent coproporphyrinogen III oxidase compare
BWI76_RS02545 -1.4 -4.3 protease modulator HflK compare
BWI76_RS17290 -1.4 -4.3 formyltetrahydrofolate deformylase compare
BWI76_RS20170 -1.4 -4.7 NADH-quinone oxidoreductase subunit F compare
BWI76_RS21140 -1.4 -1.7 molecular chaperone HscA compare
BWI76_RS20650 -1.4 -1.3 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS15835 -1.3 -1.1 hypothetical protein compare
BWI76_RS01090 -1.3 -2.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS08525 -1.3 -2.9 colicin transporter compare
BWI76_RS19495 -1.3 -1.2 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS16355 -1.3 -2.1 electron transport complex subunit A compare
BWI76_RS01325 -1.3 -1.8 twin-arginine translocase subunit TatB compare
BWI76_RS19735 -1.3 -4.1 bifunctional PTS fructose transporter subunit IIA/HPr protein compare
BWI76_RS01135 -1.3 -3.9 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS22700 -1.3 -3.5 sulfate adenylyltransferase subunit 2 compare
BWI76_RS23480 -1.3 -7.6 EAL domain-containing protein compare
BWI76_RS13595 -1.3 -3.5 transcriptional regulator compare
BWI76_RS21100 -1.3 -2.8 nucleoside-diphosphate kinase compare
BWI76_RS15760 -1.3 -1.7 hypothetical protein compare
BWI76_RS19585 -1.3 -1.9 gentisate 1,2-dioxygenase compare
BWI76_RS16910 -1.3 -2.0 2-keto-4-pentenoate hydratase compare
BWI76_RS15810 -1.3 -5.8 hypothetical protein compare
BWI76_RS21370 -1.3 -1.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS23930 -1.2 -3.1 transcriptional regulator ArgP compare
BWI76_RS25060 -1.2 -2.6 lipoprotein NlpI compare
BWI76_RS08615 -1.2 -3.1 galactokinase compare
BWI76_RS05120 -1.2 -7.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS15060 -1.2 -2.7 MarR family transcriptional regulator compare
BWI76_RS06530 -1.2 -3.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS01715 -1.2 -3.5 shikimate 5-dehydrogenase compare
BWI76_RS27165 -1.2 -3.1 mannitol-1-phosphate 5-dehydrogenase compare


Specific Phenotypes

For 15 genes in this experiment

For carbon source L-(-)-sorbose in Klebsiella michiganensis M5al

For carbon source L-(-)-sorbose across organisms