Experiment set4IT087 for Klebsiella michiganensis M5al

Compare to:

L-Sorbose carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS06540 +1.7 3.9 DNA-binding protein HU-beta compare
BWI76_RS02580 +1.7 3.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS16935 +1.4 2.0 shikimate dehydrogenase compare
BWI76_RS04715 +1.3 2.2 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS11255 +1.3 2.2 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS09730 +1.3 2.4 pyruvate formate lyase 1-activating protein compare
BWI76_RS07475 +1.3 1.5 DNA-binding transcriptional regulator RamA compare
BWI76_RS19770 +1.2 3.3 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS17900 +1.2 5.3 PTS mannose transporter subunit IID compare
BWI76_RS14505 +1.2 3.1 salicylate synthase Irp9 compare
BWI76_RS05570 +1.1 1.8 hypothetical protein compare
BWI76_RS08750 +1.1 1.7 kinase inhibitor compare
BWI76_RS21075 +1.1 1.4 membrane protein compare
BWI76_RS11170 +1.1 2.1 hypothetical protein compare
BWI76_RS11820 +1.1 1.7 short-chain dehydrogenase/reductase SDR compare
BWI76_RS10060 +1.1 2.0 acylphosphatase compare
BWI76_RS19470 +1.1 2.8 DNA-binding response regulator compare
BWI76_RS00025 +1.0 1.2 hypothetical protein compare
BWI76_RS11250 +1.0 2.2 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS17525 +1.0 2.1 XshC-Cox1-family protein compare
BWI76_RS05810 +1.0 1.7 hypothetical protein compare
BWI76_RS06810 +0.9 1.7 hypothetical protein compare
BWI76_RS11110 +0.9 2.1 cell division protein YceG compare
BWI76_RS15970 +0.9 1.2 carboxypeptidase M32 compare
BWI76_RS24470 +0.9 5.2 hypothetical protein compare
BWI76_RS17045 +0.8 1.4 hypothetical protein compare
BWI76_RS09560 +0.8 1.3 DoxX family membrane protein compare
BWI76_RS27455 +0.8 2.5 DUF805 domain-containing protein compare
BWI76_RS24525 +0.8 3.1 urease accessory protein UreG compare
BWI76_RS06910 +0.8 1.5 transcriptional regulator compare
BWI76_RS06405 +0.8 1.9 2-dehydropantoate 2-reductase compare
BWI76_RS23320 +0.8 1.5 hypothetical protein compare
BWI76_RS16395 +0.8 3.2 glutathione S-transferase compare
BWI76_RS09025 +0.8 1.8 GntR family transcriptional regulator compare
BWI76_RS03610 +0.8 2.1 hypothetical protein compare
BWI76_RS11835 +0.8 2.2 putative regulatory protein MarR compare
BWI76_RS03045 +0.8 1.0 hypothetical protein compare
BWI76_RS11345 +0.8 2.0 LysR family transcriptional regulator compare
BWI76_RS22980 +0.8 3.7 murein transglycosylase A compare
BWI76_RS17860 +0.8 1.6 YoaH family protein compare
BWI76_RS06205 +0.8 2.7 recombination-associated protein RdgC compare
BWI76_RS21115 +0.8 1.6 3-mercaptopyruvate sulfurtransferase compare
BWI76_RS26670 +0.8 5.2 two-component sensor histidine kinase compare
BWI76_RS01885 +0.8 1.1 CsbD family protein compare
BWI76_RS19775 +0.7 2.1 phage resistance protein compare
BWI76_RS06120 +0.7 2.1 membrane protein compare
BWI76_RS01000 +0.7 2.0 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS24745 +0.7 3.4 membrane protein compare
BWI76_RS07725 +0.7 0.8 iron-enterobactin transporter permease compare
BWI76_RS25545 +0.7 1.6 hypothetical protein compare
BWI76_RS20290 +0.7 2.5 thiol:disulfide oxidoreductase compare
BWI76_RS21285 +0.7 1.5 HAD family hydrolase compare
BWI76_RS00375 +0.7 2.4 hypothetical protein compare
BWI76_RS02190 +0.7 1.6 ribose 1,5-bisphosphokinase compare
BWI76_RS15415 +0.7 2.5 LacI family transcriptional regulator compare
BWI76_RS15845 +0.7 0.8 hypothetical protein compare
BWI76_RS22380 +0.7 2.5 6-phospho-beta-glucosidase compare
BWI76_RS06520 +0.7 2.2 trigger factor compare
BWI76_RS23555 +0.7 2.7 type 1 major fimbrial subunit precursor compare
BWI76_RS24520 +0.7 1.6 urease accessory protein UreF compare
BWI76_RS08645 +0.7 1.8 molybdate ABC transporter substrate-binding protein compare
BWI76_RS17890 +0.7 2.8 PTS mannose transporter subunit EIIAB compare
BWI76_RS11285 +0.7 1.3 transcriptional regulator compare
BWI76_RS10725 +0.7 0.9 hypothetical protein compare
BWI76_RS23825 +0.7 5.0 hypothetical protein compare
BWI76_RS04815 +0.7 2.3 cell division protein ZapD compare
BWI76_RS25630 +0.7 2.3 hypothetical protein compare
BWI76_RS08985 +0.7 2.5 threonine/homoserine exporter RhtA compare
BWI76_RS12420 +0.7 0.8 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS01630 +0.7 0.9 16S ribosomal RNA compare
BWI76_RS13445 +0.7 1.4 alpha/beta hydrolase compare
BWI76_RS26045 +0.7 1.3 nitrite reductase small subunit compare
BWI76_RS15190 +0.7 3.5 GGDEF domain-containing protein compare
BWI76_RS05045 +0.7 1.9 general secretion pathway protein GspM compare
BWI76_RS18335 +0.6 4.3 DNA-binding response regulator compare
BWI76_RS08485 +0.6 4.0 glutamate mutase compare
BWI76_RS09325 +0.6 2.1 putative bacteriophage tail completion protein compare
BWI76_RS09500 +0.6 2.3 arginine ABC transporter substrate-binding protein compare
BWI76_RS00755 +0.6 2.2 ATP-dependent protease subunit HslV compare
BWI76_RS12860 +0.6 1.6 hypothetical protein compare
BWI76_RS17325 +0.6 2.2 nitrate reductase molybdenum cofactor assembly chaperone compare
BWI76_RS08655 +0.6 1.5 molybdenum ABC transporter ATP-binding protein compare
BWI76_RS13330 +0.6 1.1 tellurite resistance methyltransferase TehB compare
BWI76_RS12975 +0.6 2.7 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS08380 +0.6 0.5 endonuclease VIII compare
BWI76_RS09320 +0.6 1.5 P2 phage tail completion protein R compare
BWI76_RS10040 +0.6 1.4 heat-shock protein HspQ compare
BWI76_RS25485 +0.6 1.2 septum formation protein Maf compare
BWI76_RS22425 +0.6 2.2 metal ABC transporter substrate-binding protein compare
BWI76_RS01140 +0.6 3.3 amino acid permease compare
BWI76_RS15050 +0.6 1.6 sugar transporter compare
BWI76_RS02175 +0.6 2.7 ribose 5-phosphate isomerase B compare
BWI76_RS25480 +0.6 1.9 ribonuclease E/G compare
BWI76_RS09520 +0.6 1.1 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS15210 +0.6 2.7 LysR family transcriptional regulator compare
BWI76_RS14170 +0.6 1.7 hypothetical protein compare
BWI76_RS26580 +0.6 2.6 universal stress protein A compare
BWI76_RS13755 +0.6 1.2 hypothetical protein compare
BWI76_RS19850 +0.6 1.8 tRNA-Pro compare
BWI76_RS14780 +0.6 2.4 phosphotriesterase compare
BWI76_RS16640 +0.6 2.4 threonine transporter compare
BWI76_RS18800 +0.6 2.0 transcriptional regulator compare
BWI76_RS22815 +0.6 4.1 hybrid sensor histidine kinase/response regulator compare
BWI76_RS24115 +0.6 2.7 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family compare
BWI76_RS26665 +0.6 1.7 DNA-binding response regulator compare
BWI76_RS05510 +0.6 1.7 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS11665 +0.6 1.1 exodeoxyribonuclease III compare
BWI76_RS12235 +0.6 1.2 hypothetical protein compare
BWI76_RS13380 +0.6 1.5 hypothetical protein compare
BWI76_RS27875 +0.6 0.7 membrane protein compare
BWI76_RS26365 +0.6 3.0 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS01585 +0.6 2.3 transcriptional regulator compare
BWI76_RS08650 +0.6 1.3 molybdate ABC transporter permease compare
BWI76_RS03180 +0.6 1.6 phage transcriptional regulator, AlpA compare
BWI76_RS05880 +0.6 1.4 AraC-type DNA-binding domain-containing protein compare
BWI76_RS23700 +0.6 2.7 glycerate CoA-transferase (from data) compare
BWI76_RS14770 +0.6 0.9 PTS IIA 2 domain protein compare
BWI76_RS13730 +0.6 1.2 hypothetical protein compare
BWI76_RS01565 +0.6 1.1 NADH pyrophosphatase compare
BWI76_RS16210 +0.6 0.6 hypothetical protein compare
BWI76_RS09680 +0.6 2.6 dimethyl sulfoxide reductase subunit A compare
BWI76_RS02800 +0.6 2.3 ABC transporter compare
BWI76_RS16920 +0.6 0.6 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS07790 +0.6 1.4 plasmid stabilization protein compare
BWI76_RS13685 +0.6 1.1 IclR family transcriptional regulator compare
BWI76_RS06130 +0.6 1.6 extensin family protein compare
BWI76_RS02255 +0.6 1.7 chaperone-modulator protein CbpM compare
BWI76_RS10285 +0.6 2.4 family 3 extracellular solute-binding protein compare
BWI76_RS17895 +0.6 2.1 PTS mannose/fructose/sorbose transporter subunit IIC compare
BWI76_RS10900 +0.6 1.5 putative oxidoreductase compare
BWI76_RS12680 +0.6 1.8 oxidoreductase compare
BWI76_RS22835 +0.6 2.3 MFS transporter compare
BWI76_RS05945 +0.6 1.7 amino acid ABC transporter permease compare
BWI76_RS22410 +0.6 1.3 PTS lactose/cellobiose transporter subunit IIA compare
BWI76_RS11770 +0.6 1.5 hypothetical protein compare
BWI76_RS25300 +0.6 1.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS05555 +0.6 1.8 Crl family RNA polymerase assembly factor compare
BWI76_RS07510 +0.6 1.5 hypothetical protein compare
BWI76_RS27425 +0.6 1.0 DNA-directed RNA polymerase subunit omega compare
BWI76_RS00690 +0.6 3.2 transcriptional activator RhaS compare
BWI76_RS12465 +0.6 0.7 phage shock protein D compare
BWI76_RS11125 +0.5 0.9 metal-dependent hydrolase compare
BWI76_RS18035 +0.5 3.0 fimbrial chaperone compare
BWI76_RS27200 +0.5 2.6 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL compare
BWI76_RS02635 +0.5 1.9 3-keto-L-gulonate-6-phosphate decarboxylase compare
BWI76_RS13745 +0.5 2.5 formate dehydrogenase subunit beta compare
BWI76_RS25000 +0.5 0.5 malonate decarboxylase acyl carrier protein compare
BWI76_RS22620 +0.5 1.3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase compare
BWI76_RS20795 +0.5 0.8 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS16040 +0.5 1.4 biotin-independent malonate decarboxylase subunit gamma compare
BWI76_RS02690 +0.5 1.4 hypothetical protein compare
BWI76_RS16500 +0.5 1.8 superoxide dismutase [Fe] compare
BWI76_RS22945 +0.5 1.6 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM compare
BWI76_RS17390 +0.5 1.5 DsrE family protein compare
BWI76_RS21740 +0.5 1.7 transcriptional regulator, LysR family protein compare
BWI76_RS15800 +0.5 1.9 transcriptional regulator compare
BWI76_RS01895 +0.5 1.9 cupin compare
BWI76_RS11600 +0.5 2.1 selenide, water dikinase SelD compare
BWI76_RS24055 +0.5 2.2 MFS transporter compare
BWI76_RS17070 +0.5 2.1 phosphoenolpyruvate synthase regulatory protein compare
BWI76_RS10575 +0.5 0.9 polar amino acid ABC transporter permease compare
BWI76_RS22475 +0.5 1.4 heme ABC transporter ATP-binding protein compare
BWI76_RS23215 +0.5 2.4 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS26410 +0.5 1.1 membrane protein compare
BWI76_RS18065 +0.5 1.1 DNA polymerase III subunit theta compare
BWI76_RS17775 +0.5 1.7 hypothetical protein compare
BWI76_RS17715 +0.5 2.3 murein transglycosylase compare
BWI76_RS11675 +0.5 1.2 arginine N-succinyltransferase compare
BWI76_RS03020 +0.5 1.5 tRNA hydroxylase compare
BWI76_RS08625 +0.5 1.2 UDP-glucose 4-epimerase GalE compare
BWI76_RS07830 +0.5 2.5 3-phytase compare
BWI76_RS21870 +0.5 2.3 hypothetical protein compare
BWI76_RS19240 +0.5 0.9 ABC transporter substrate-binding protein compare
BWI76_RS23960 +0.5 1.5 oxidative stress defense protein compare
BWI76_RS21470 +0.5 0.8 gluconolaconase compare
BWI76_RS11765 +0.5 3.1 bifunctional transporter/kinase compare
BWI76_RS20615 +0.5 2.0 sodium symporter compare
BWI76_RS15980 +0.5 1.1 lysine transporter LysE compare
BWI76_RS21920 +0.5 2.1 amino acid ABC transporter substrate-binding protein compare
BWI76_RS16630 +0.5 2.1 MBL fold metallo-hydrolase compare
BWI76_RS06240 +0.5 1.3 branched-chain amino acid transport system 2 carrier protein BrnQ compare
BWI76_RS16870 +0.5 1.1 LysR family transcriptional regulator compare
BWI76_RS15975 +0.5 0.6 hypothetical protein compare
BWI76_RS23905 +0.5 2.6 Z-ring-associated protein compare
BWI76_RS19330 +0.5 0.6 HAD family hydrolase compare
BWI76_RS25165 +0.5 2.9 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS24105 +0.5 1.4 resistance protein compare
BWI76_RS07380 +0.5 0.9 hypothetical protein compare
BWI76_RS20880 +0.5 1.0 esterase compare
BWI76_RS14375 +0.5 1.5 hypothetical protein compare
BWI76_RS03315 +0.5 2.1 clavaldehyde dehydrogenase compare
BWI76_RS02050 +0.5 1.0 CidA/LrgA family protein compare
BWI76_RS01840 +0.5 1.9 maltose ABC transporter, ATPase component (MalK) (from data) compare
BWI76_RS05075 +0.5 0.6 type II secretion system protein GspG compare
BWI76_RS07755 +0.5 1.6 isochorismatase compare
BWI76_RS02805 +0.5 2.3 sugar ABC transporter permease compare
BWI76_RS08775 +0.5 2.2 dethiobiotin synthase compare
BWI76_RS09750 +0.5 2.3 DUF421 domain-containing protein compare
BWI76_RS00800 +0.5 2.1 LysR family transcriptional regulator compare
BWI76_RS14980 +0.5 1.0 hypothetical protein compare


Specific Phenotypes

For 15 genes in this experiment

For carbon source L-(-)-sorbose in Klebsiella michiganensis M5al

For carbon source L-(-)-sorbose across organisms