Experiment set4IT087 for Klebsiella michiganensis M5al

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L-Sorbose carbon source

Group: carbon source
Media: RCH2_defined_noCarbon + L-(-)-sorbose (20 mM), pH=7
Culturing: Koxy_ML2, 24-well transparent microplate; Multitron, Aerobic, at 30 (C), shaken=700 rpm
By: Adam on 27-Mar-17
Media components: 0.25 g/L Ammonium chloride, 0.1 g/L Potassium Chloride, 0.6 g/L Sodium phosphate monobasic monohydrate, 30 mM PIPES sesquisodium salt, Wolfe's mineral mix (0.03 g/L Magnesium Sulfate Heptahydrate, 0.015 g/L Nitrilotriacetic acid, 0.01 g/L Sodium Chloride, 0.005 g/L Manganese (II) sulfate monohydrate, 0.001 g/L Cobalt chloride hexahydrate, 0.001 g/L Zinc sulfate heptahydrate, 0.001 g/L Calcium chloride dihydrate, 0.001 g/L Iron (II) sulfate heptahydrate, 0.00025 g/L Nickel (II) chloride hexahydrate, 0.0002 g/L Aluminum potassium sulfate dodecahydrate, 0.0001 g/L Copper (II) sulfate pentahydrate, 0.0001 g/L Boric Acid, 0.0001 g/L Sodium Molybdate Dihydrate, 0.003 mg/L Sodium selenite pentahydrate), Wolfe's vitamin mix (0.1 mg/L Pyridoxine HCl, 0.05 mg/L 4-Aminobenzoic acid, 0.05 mg/L Lipoic acid, 0.05 mg/L Nicotinic Acid, 0.05 mg/L Riboflavin, 0.05 mg/L Thiamine HCl, 0.05 mg/L calcium pantothenate, 0.02 mg/L biotin, 0.02 mg/L Folic Acid, 0.001 mg/L Cyanocobalamin)
Growth plate: 1763 A6

Specific Phenotypes

For 15 genes in this experiment

For carbon source L-(-)-sorbose in Klebsiella michiganensis M5al

For carbon source L-(-)-sorbose across organisms

SEED Subsystems

Subsystem #Specific
D-Sorbitol(D-Glucitol) and L-Sorbose Utilization 5
Glycerol and Glycerol-3-phosphate Uptake and Utilization 2
Entner-Doudoroff Pathway 1
Glycerol fermenation to 1,3-propanediol 1
Glycerolipid and Glycerophospholipid Metabolism in Bacteria 1
Glycolysis and Gluconeogenesis 1
MLST 1
Phosphate metabolism 1
Sucrose utilization 1
Sugar-phosphate stress regulation 1

Metabolic Maps

Color code by fitness: see overview map or list of maps.

Maps containing gene(s) with specific phenotypes:

MetaCyc Pathways

Pathways that contain genes with specific phenotypes:

Pathway #Steps #Present #Specific
L-sorbose degradation 2 2 2
D-sorbitol degradation II 1 1 1
glycerol degradation I 3 3 2
glycerol and glycerophosphodiester degradation 4 4 2
D-mannose degradation I 2 2 1
arsenate detoxification III 2 2 1
trehalose degradation II (cytosolic) 2 2 1
trehalose degradation I (low osmolarity) 2 2 1
NAD phosphorylation and transhydrogenation 2 2 1
NAD phosphorylation and dephosphorylation 3 3 1
trehalose degradation V 3 2 1
GDP-α-D-glucose biosynthesis 3 2 1
D-glucosaminate degradation 3 2 1
trehalose degradation IV 3 1 1
sucrose degradation III (sucrose invertase) 4 4 1
glucose and glucose-1-phosphate degradation 5 5 1
arsenic detoxification (plants) 6 5 1
UDP-N-acetyl-D-glucosamine biosynthesis II 6 4 1
NAD(P)/NADPH interconversion 6 4 1
glycogen degradation II 6 4 1
UDP-N-acetyl-D-galactosamine biosynthesis II 7 4 1
glycogen degradation I 8 8 1
sucrose biosynthesis II 8 6 1
chitin derivatives degradation 8 4 1
1,3-propanediol biosynthesis (engineered) 9 7 1
chitin biosynthesis 9 6 1
glycolysis III (from glucose) 11 11 1
homolactic fermentation 12 12 1
arsenic detoxification (yeast) 12 4 1
glycolysis I (from glucose 6-phosphate) 13 13 1
Bifidobacterium shunt 15 13 1
superpathway of glycolysis and the Entner-Doudoroff pathway 17 17 1
arsenic detoxification (mammals) 17 8 1
superpathway of hexitol degradation (bacteria) 18 18 1
heterolactic fermentation 18 16 1
hexitol fermentation to lactate, formate, ethanol and acetate 19 19 1
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass 26 25 1