Experiment set4IT084 for Methanococcus maripaludis S2

Compare to:

Formate deepwell autotrophic conditions

200 most important genes:

  gene name fitness t score description  
MMP_RS03450 -4.3 -4.8 glycine synthesis protein GlyXS (from data) compare
MMP_RS05100 -4.1 -25.3 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05095 -4.1 -16.1 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06700 -4.1 -19.5 hypothetical protein compare
MMP_RS05085 -4.0 -18.3 AAA family ATPase compare
MMP_RS06715 -4.0 -24.5 cache domain-containing protein compare
MMP_RS07345 -3.9 -9.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS05060 -3.9 -14.7 AAA family ATPase compare
MMP_RS05075 -3.9 -22.2 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05055 -3.9 -21.6 DUF166 domain-containing protein compare
MMP_RS05080 -3.8 -21.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS05090 -3.8 -15.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06680 -3.8 -18.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06350 -3.8 -8.7 HesA/MoeB/ThiF family protein compare
MMP_RS06705 -3.8 -7.1 formate/nitrite transporter family protein compare
MMP_RS05070 -3.8 -11.0 4Fe-4S dicluster domain-containing protein compare
MMP_RS06685 -3.8 -16.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04620 -3.7 -17.0 cobalt transporter CbiM compare
MMP_RS06315 -3.7 -2.0 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06720 -3.6 -11.4 response regulator transcription factor compare
MMP_RS03015 -3.6 -13.9 GTP 3' 8-cyclase MoaA compare
MMP_RS01500 -3.5 -4.3 CBS domain-containing protein compare
MMP_RS05500 -3.5 -13.3 2-isopropylmalate synthase compare
MMP_RS07445 -3.4 -15.1 helix-turn-helix domain-containing protein compare
MMP_RS01175 -3.4 -7.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05515 -3.3 -13.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05065 -3.3 -8.4 CooT family nickel-binding protein compare
MMP_RS03640 -3.3 -5.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04615 -3.3 -6.1 PDGLE domain-containing protein compare
MMP_RS07735 -3.3 -1.9 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06345 -3.2 -12.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07845 -3.1 -5.3 LL-diaminopimelate aminotransferase compare
MMP_RS04605 -3.1 -8.1 cobalt ECF transporter T component CbiQ compare
MMP_RS07005 -3.0 -1.5 4Fe-4S binding protein compare
MMP_RS08745 -3.0 -8.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07635 -3.0 -8.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07365 -3.0 -16.1 2-phosphoglycerate kinase compare
MMP_RS06355 -3.0 -5.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS09020 -2.9 -3.5 hypothetical protein compare
MMP_RS00515 -2.9 -1.9 DUF655 domain-containing protein compare
MMP_RS07575 -2.9 -8.9 RNA ligase partner protein compare
MMP_RS06400 -2.8 -3.1 4Fe-4S binding protein compare
MMP_RS03035 -2.7 -7.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00295 -2.7 -4.7 gamma carbonic anhydrase family protein compare
MMP_RS01455 -2.7 -12.6 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS07525 -2.7 -10.9 4Fe-4S binding protein compare
MMP_RS07720 -2.6 -17.7 4Fe-4S binding protein compare
MMP_RS01005 -2.6 -3.0 riboflavin synthase compare
MMP_RS01380 -2.6 -5.9 PHP domain-containing protein compare
MMP_RS03435 -2.6 -4.2 ketol-acid reductoisomerase compare
MMP_RS06375 -2.6 -7.8 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS01545 -2.6 -2.4 CBS domain-containing protein compare
MMP_RS01755 -2.6 -2.7 DUF2097 domain-containing protein compare
MMP_RS00985 -2.5 -6.2 CDC48 family AAA ATPase compare
MMP_RS05555 -2.5 -2.7 DUF4040 domain-containing protein compare
MMP_RS05850 -2.5 -5.8 Ldh family oxidoreductase compare
MMP_RS01610 -2.5 -7.0 hypothetical protein compare
MMP_RS01700 -2.5 -2.1 dihydroxy-acid dehydratase compare
MMP_RS05425 -2.4 -9.6 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06105 -2.4 -14.5 hydrogenase maturation peptidase HycI compare
MMP_RS08820 -2.4 -10.7 hypothetical protein compare
MMP_RS05930 -2.4 -4.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS06340 -2.4 -12.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02195 -2.4 -7.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07730 -2.4 -4.1 pyruvate synthase subunit beta compare
MMP_RS04215 -2.3 -12.7 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS06270 -2.3 -7.8 TIGR00300 family protein compare
MMP_RS02900 -2.3 -1.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08720 -2.3 -3.2 4Fe-4S binding protein compare
MMP_RS01985 -2.3 -10.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01020 -2.3 -2.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01225 -2.3 -9.5 DUF5379 domain-containing protein compare
MMP_RS00290 -2.3 -7.2 hypothetical protein compare
MMP_RS06925 -2.3 -5.3 ribonuclease VapC4 compare
MMP_RS02135 -2.2 -10.3 DUF5612 domain-containing protein compare
MMP_RS02340 -2.2 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS02800 -2.2 -5.6 nucleotidyltransferase domain-containing protein compare
MMP_RS08240 -2.2 -11.0 methanogenesis marker 16 metalloprotein compare
MMP_RS06625 -2.1 -4.7 DNA primase compare
MMP_RS01325 -2.1 -3.9 dihydroneopterin aldolase family protein compare
MMP_RS05875 -2.1 -7.2 hydroxyethylthiazole kinase compare
MMP_RS04585 -2.1 -10.0 AIR synthase related protein compare
MMP_RS05845 -2.1 -2.9 tRNA-intron lyase compare
MMP_RS02355 -2.1 -4.5 30S ribosomal protein S27ae compare
MMP_RS06630 -2.1 -2.3 UPF0058 family protein compare
MMP_RS00685 -2.1 -7.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08330 -2.1 -7.3 NADH-quinone oxidoreductase subunit H compare
MMP_RS08165 -2.0 -2.4 phosphoglycerate dehydrogenase compare
MMP_RS08645 -2.0 -9.2 UPF0179 family protein compare
MMP_RS07185 -2.0 -15.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06295 -2.0 -8.4 methanogenesis marker 14 protein compare
MMP_RS08210 -2.0 -2.2 phosphatidylglycerophosphatase A compare
MMP_RS06730 -2.0 -3.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS01475 -1.9 -8.2 phosphosulfolactate synthase compare
MMP_RS07380 -1.9 -2.6 transcription elongation factor Spt5 compare
MMP_RS03025 -1.9 -8.0 molybdenum cofactor guanylyltransferase compare
MMP_RS03315 -1.9 -1.8 ferrous iron transport protein A compare
MMP_RS01800 -1.9 -4.2 TIGR00303 family protein compare
MMP_RS05925 -1.9 -4.7 small nuclear ribonucleoprotein compare
MMP_RS02010 -1.9 -9.6 PHP domain-containing protein compare
MMP_RS08635 -1.9 -2.8 UbiA family prenyltransferase compare
MMP_RS02875 -1.9 -11.4 chorismate pyruvate-lyase family protein compare
MMP_RS06120 -1.9 -3.8 UPF0147 family protein compare
MMP_RS06370 -1.8 -4.7 biotin synthase BioB compare
MMP_RS04500 -1.8 -13.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS01265 -1.8 -3.6 hypothetical protein compare
MMP_RS05550 -1.8 -1.2 cation:proton antiporter compare
MMP_RS05540 -1.8 -3.3 hypothetical protein compare
MMP_RS08095 -1.8 -10.8 dethiobiotin synthase compare
MMP_RS05920 -1.7 -1.2 50S ribosomal protein L37e compare
MMP_RS00895 -1.7 -4.4 hypothetical protein compare
MMP_RS01830 -1.7 -2.1 tRNA-Val compare
MMP_RS00455 -1.7 -11.7 orotate phosphoribosyltransferase-like protein compare
MMP_RS06175 -1.7 -9.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06975 -1.7 -3.6 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07630 -1.7 -2.2 ATP-binding cassette domain-containing protein compare
MMP_RS03600 -1.6 -2.9 triose-phosphate isomerase compare
MMP_RS05765 -1.6 -7.3 M42 family metallopeptidase compare
MMP_RS03420 -1.6 -3.3 acetolactate synthase small subunit compare
MMP_RS04875 -1.6 -7.8 energy-converting hydrogenase B subunit P compare
MMP_RS08715 -1.6 -3.1 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07605 -1.6 -5.1 diadenylate cyclase compare
MMP_RS08105 -1.6 -9.7 6-carboxyhexanoate--CoA ligase compare
MMP_RS07645 -1.6 -7.1 aldehyde dehydrogenase family protein compare
MMP_RS03140 -1.6 -12.2 hypothetical protein compare
MMP_RS08790 -1.5 -3.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS08460 -1.5 -2.9 proteasome-activating nucleotidase compare
MMP_RS02235 -1.5 -10.6 CBS domain-containing protein compare
MMP_RS02170 -1.5 -5.2 CBS domain-containing protein compare
MMP_RS07710 -1.5 -9.8 cell division protein FtsZ compare
MMP_RS06020 -1.5 -4.6 archaeoflavoprotein AfpA compare
MMP_RS00750 -1.5 -4.0 fumarate hydratase compare
MMP_RS05505 -1.5 -7.8 class IV adenylate cyclase compare
MMP_RS06200 -1.5 -9.9 M24 family metallopeptidase compare
MMP_RS03580 -1.5 -4.7 signal recognition particle-docking protein FtsY compare
MMP_RS07955 -1.5 -7.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06230 -1.5 -3.4 helix-turn-helix domain-containing protein compare
MMP_RS02165 -1.5 -7.9 tRNA-dihydrouridine synthase compare
MMP_RS04710 -1.5 -1.9 hypothetical protein compare
MMP_RS08100 -1.5 -7.0 8-amino-7-oxononanoate synthase compare
MMP_RS07555 -1.5 -1.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS03700 -1.5 -7.9 sodium:proton antiporter compare
MMP_RS05430 -1.5 -5.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS03445 -1.4 -1.6 methanogenesis marker 17 protein compare
MMP_RS05265 -1.4 -2.2 2-isopropylmalate synthase compare
MMP_RS04790 -1.4 -9.4 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01220 -1.4 -8.5 hypothetical protein compare
MMP_RS08320 -1.4 -6.1 molybdopterin molybdotransferase MoeA compare
MMP_RS08760 -1.4 -2.3 hypothetical protein compare
MMP_RS00695 -1.4 -1.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS03305 -1.4 -9.4 winged helix-turn-helix domain-containing protein compare
MMP_RS01365 -1.4 -3.0 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07685 -1.4 -7.6 TIGR01212 family radical SAM protein compare
MMP_RS06395 -1.4 -4.4 ThiF family adenylyltransferase compare
MMP_RS03400 -1.4 -3.9 archease compare
MMP_RS00115 -1.3 -10.2 radical SAM protein compare
MMP_RS00320 -1.3 -3.0 class I SAM-dependent methyltransferase compare
MMP_RS06895 -1.3 -3.1 selenocysteine-specific translation elongation factor compare
MMP_RS04870 -1.3 -5.4 TIGR02253 family HAD-type hydrolase compare
MMP_RS00620 -1.3 -7.1 4Fe-4S binding protein compare
MMP_RS06215 -1.3 -4.7 30S ribosomal protein S6e compare
MMP_RS07195 -1.3 -8.5 M20 family metallo-hydrolase compare
MMP_RS03205 -1.3 -1.6 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02240 -1.3 -3.6 methanogenesis marker 7 protein compare
MMP_RS04685 -1.3 -2.9 DUF126 domain-containing protein compare
MMP_RS08370 -1.3 -1.1 cation:proton antiporter subunit C compare
MMP_RS00300 -1.2 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03145 -1.2 -6.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS01795 -1.2 -2.1 methanogenesis marker 6 protein compare
MMP_RS03155 -1.2 -7.1 precorrin-6A reductase compare
MMP_RS00120 -1.2 -4.0 LysR family transcriptional regulator compare
MMP_RS02190 -1.2 -3.0 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS02280 -1.2 -1.3 DUF211 domain-containing protein compare
MMP_RS06885 -1.2 -4.1 50S ribosome-binding GTPase compare
MMP_RS08435 -1.2 -2.1 Era-like GTP-binding protein compare
MMP_RS07200 -1.2 -6.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS03960 -1.2 -1.2 hypothetical protein compare
MMP_RS03095 -1.1 -6.3 diphthine synthase compare
MMP_RS08445 -1.1 -4.8 DUF2099 family protein compare
MMP_RS06930 -1.1 -7.6 MBL fold metallo-hydrolase compare
MMP_RS04780 -1.1 -2.5 ribonuclease P compare
MMP_RS07700 -1.1 -6.5 DUF1188 domain-containing protein compare
MMP_RS00305 -1.1 -1.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS02885 -1.1 -8.4 molybdopterin biosynthesis protein compare
MMP_RS07425 -1.1 -4.3 GTP-binding protein compare
MMP_RS07600 -1.1 -3.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS00725 -1.1 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS03250 -1.1 -2.2 MJ1244 family protein compare
MMP_RS06865 -1.0 -2.4 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07535 -1.0 -6.7 4Fe-4S binding protein compare
MMP_RS07695 -1.0 -5.1 DUF3236 domain-containing protein compare
MMP_RS00735 -1.0 -4.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04775 -1.0 -2.8 adenosylhomocysteinase compare
MMP_RS04890 -1.0 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05545 -1.0 -5.5 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06130 -1.0 -3.2 peptidylprolyl isomerase compare
MMP_RS00475 -1.0 -5.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05250 -1.0 -1.7 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01865 -1.0 -2.1 GPR1/FUN34/YaaH family transporter compare
MMP_RS07705 -0.9 -6.3 transcriptional regulator compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments