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Experiment set4IT083 for
Methanococcus maripaludis S2
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Formate deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS03315
-5.8
-3.1
ferrous iron transport protein A
compare
MMP
_RS00300
-4.8
-1.5
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS03640
-4.7
-6.4
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS06315
-4.5
-1.9
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS05090
-4.4
-14.2
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS05100
-4.2
-27.8
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS00295
-4.2
-4.7
gamma carbonic anhydrase family protein
compare
MMP
_RS06685
-4.2
-15.8
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS05085
-4.2
-20.0
AAA family ATPase
compare
MMP
_RS04605
-4.1
-11.0
cobalt ECF transporter T component CbiQ
compare
MMP
_RS05075
-4.1
-24.1
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS05080
-4.1
-20.0
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS06680
-4.0
-21.9
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS05070
-4.0
-12.6
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS05055
-4.0
-24.8
DUF166 domain-containing protein
compare
MMP
_RS05060
-4.0
-22.6
AAA family ATPase
compare
MMP
_RS06345
-4.0
-11.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS06705
-3.9
-12.1
formate/nitrite transporter family protein
compare
MMP
_RS06700
-3.9
-18.8
hypothetical protein
compare
MMP
_RS07735
-3.9
-1.6
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS07345
-3.9
-9.3
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS07845
-3.9
-6.4
LL-diaminopimelate aminotransferase
compare
MMP
_RS06715
-3.8
-23.0
cache domain-containing protein
compare
MMP
_RS05095
-3.8
-16.4
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS07630
-3.7
-3.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS04620
-3.7
-16.0
cobalt transporter CbiM
compare
MMP
_RS07005
-3.6
-1.5
4Fe-4S binding protein
compare
MMP
_RS06720
-3.6
-11.8
response regulator transcription factor
compare
MMP
_RS06350
-3.6
-8.8
HesA/MoeB/ThiF family protein
compare
MMP
_RS05515
-3.5
-11.6
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06625
-3.5
-3.4
DNA primase
compare
MMP
_RS01380
-3.4
-7.4
PHP domain-containing protein
compare
MMP
_RS05500
-3.4
-14.3
2-isopropylmalate synthase
compare
MMP
_RS08790
-3.3
-4.7
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS05065
-3.3
-6.8
CooT family nickel-binding protein
compare
MMP
_RS06355
-3.3
-3.8
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS03015
-3.2
-13.5
GTP 3' 8-cyclase MoaA
compare
MMP
_RS07730
-3.2
-4.0
pyruvate synthase subunit beta
compare
MMP
_RS01005
-3.1
-3.2
riboflavin synthase
compare
MMP
_RS07445
-3.1
-15.6
helix-turn-helix domain-containing protein
compare
MMP
_RS03450
-3.1
-3.5
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS08745
-3.1
-10.2
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS04615
-3.1
-8.8
PDGLE domain-containing protein
compare
MMP
_RS02900
-3.0
-1.6
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS03035
-3.0
-5.4
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS06340
-3.0
-10.9
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS01500
-3.0
-4.5
CBS domain-containing protein
compare
MMP
_RS07635
-2.9
-11.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS07365
-2.9
-15.2
2-phosphoglycerate kinase
compare
MMP
_RS07525
-2.9
-13.1
4Fe-4S binding protein
compare
MMP
_RS01265
-2.9
-7.0
hypothetical protein
compare
MMP
_RS07380
-2.9
-4.8
transcription elongation factor Spt5
compare
MMP
_RS07720
-2.9
-17.2
4Fe-4S binding protein
compare
MMP
_RS06270
-2.8
-10.0
TIGR00300 family protein
compare
MMP
_RS01175
-2.8
-7.2
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06400
-2.7
-3.4
4Fe-4S binding protein
compare
MMP
_RS01020
-2.7
-2.2
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS04890
-2.7
-2.0
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS00290
-2.7
-10.0
hypothetical protein
compare
MMP
_RS01325
-2.7
-3.9
dihydroneopterin aldolase family protein
compare
MMP
_RS01455
-2.6
-12.1
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS08210
-2.5
-3.4
phosphatidylglycerophosphatase A
compare
MMP
_RS01985
-2.5
-7.0
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS07575
-2.5
-9.6
RNA ligase partner protein
compare
MMP
_RS05425
-2.5
-8.0
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS03435
-2.4
-2.9
ketol-acid reductoisomerase
compare
MMP
_RS05930
-2.4
-3.2
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS02195
-2.4
-5.4
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS01610
-2.4
-7.0
hypothetical protein
compare
MMP
_RS06730
-2.4
-3.9
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS08240
-2.3
-9.8
methanogenesis marker 16 metalloprotein
compare
MMP
_RS01545
-2.3
-2.4
CBS domain-containing protein
compare
MMP
_RS05550
-2.3
-1.4
cation:proton antiporter
compare
MMP
_RS08165
-2.3
-3.0
phosphoglycerate dehydrogenase
compare
MMP
_RS05875
-2.3
-5.7
hydroxyethylthiazole kinase
compare
MMP
_RS02800
-2.3
-5.9
nucleotidyltransferase domain-containing protein
compare
MMP
_RS04215
-2.3
-12.5
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS08720
-2.2
-2.8
4Fe-4S binding protein
compare
MMP
_RS00305
-2.2
-3.2
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS02355
-2.2
-5.8
30S ribosomal protein S27ae
compare
MMP
_RS08095
-2.2
-9.8
dethiobiotin synthase
compare
MMP
_RS08300
-2.2
-1.3
metal-sulfur cluster assembly factor
compare
MMP
_RS05850
-2.2
-6.8
Ldh family oxidoreductase
compare
MMP
_RS01700
-2.2
-2.2
dihydroxy-acid dehydratase
compare
MMP
_RS08645
-2.2
-9.3
UPF0179 family protein
compare
MMP
_RS07185
-2.1
-12.3
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS03420
-2.1
-5.3
acetolactate synthase small subunit
compare
MMP
_RS08820
-2.1
-8.7
hypothetical protein
compare
MMP
_RS04585
-2.1
-11.0
AIR synthase related protein
compare
MMP
_RS06375
-2.1
-9.2
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS06630
-2.1
-2.1
UPF0058 family protein
compare
MMP
_RS07605
-2.1
-5.1
diadenylate cyclase
compare
MMP
_RS06370
-2.1
-8.2
biotin synthase BioB
compare
MMP
_RS06895
-2.0
-3.4
selenocysteine-specific translation elongation factor
compare
MMP
_RS06295
-2.0
-8.6
methanogenesis marker 14 protein
compare
MMP
_RS06105
-2.0
-10.1
hydrogenase maturation peptidase HycI
compare
MMP
_RS02875
-2.0
-10.7
chorismate pyruvate-lyase family protein
compare
MMP
_RS08715
-2.0
-2.4
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS05555
-2.0
-2.7
DUF4040 domain-containing protein
compare
MMP
_RS01755
-2.0
-2.6
DUF2097 domain-containing protein
compare
MMP
_RS02010
-2.0
-10.6
PHP domain-containing protein
compare
MMP
_RS09020
-2.0
-1.9
hypothetical protein
compare
MMP
_RS04500
-1.9
-15.0
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS07645
-1.9
-8.9
aldehyde dehydrogenase family protein
compare
MMP
_RS08330
-1.9
-5.3
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS03600
-1.9
-3.2
triose-phosphate isomerase
compare
MMP
_RS06925
-1.9
-3.6
ribonuclease VapC4
compare
MMP
_RS00985
-1.9
-9.4
CDC48 family AAA ATPase
compare
MMP
_RS04780
-1.9
-5.1
ribonuclease P
compare
MMP
_RS06885
-1.8
-4.2
50S ribosome-binding GTPase
compare
MMP
_RS05925
-1.8
-5.8
small nuclear ribonucleoprotein
compare
MMP
_RS01475
-1.8
-8.6
phosphosulfolactate synthase
compare
MMP
_RS00695
-1.8
-1.7
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS00750
-1.8
-4.4
fumarate hydratase
compare
MMP
_RS02240
-1.8
-5.6
methanogenesis marker 7 protein
compare
MMP
_RS05265
-1.8
-4.1
2-isopropylmalate synthase
compare
MMP
_RS03025
-1.8
-8.0
molybdenum cofactor guanylyltransferase
compare
MMP
_RS02135
-1.8
-5.7
DUF5612 domain-containing protein
compare
MMP
_RS05765
-1.8
-8.7
M42 family metallopeptidase
compare
MMP
_RS04685
-1.7
-4.3
DUF126 domain-containing protein
compare
MMP
_RS03140
-1.7
-12.1
hypothetical protein
compare
MMP
_RS01830
-1.7
-3.1
tRNA-Val
compare
MMP
_RS07555
-1.7
-1.4
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS02340
-1.7
-3.3
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS00115
-1.7
-12.3
radical SAM protein
compare
MMP
_RS00895
-1.7
-4.9
hypothetical protein
compare
MMP
_RS04790
-1.7
-13.2
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS04710
-1.7
-2.6
hypothetical protein
compare
MMP
_RS00620
-1.7
-9.4
4Fe-4S binding protein
compare
MMP
_RS08635
-1.6
-3.2
UbiA family prenyltransferase
compare
MMP
_RS01225
-1.6
-6.4
DUF5379 domain-containing protein
compare
MMP
_RS03580
-1.6
-5.3
signal recognition particle-docking protein FtsY
compare
MMP
_RS00685
-1.6
-4.1
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS08650
-1.6
-4.1
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS06285
-1.6
-3.7
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS07710
-1.6
-9.1
cell division protein FtsZ
compare
MMP
_RS05540
-1.6
-3.8
hypothetical protein
compare
MMP
_RS07685
-1.6
-7.8
TIGR01212 family radical SAM protein
compare
MMP
_RS02170
-1.5
-7.1
CBS domain-containing protein
compare
MMP
_RS08100
-1.5
-10.2
8-amino-7-oxononanoate synthase
compare
MMP
_RS00455
-1.5
-10.6
orotate phosphoribosyltransferase-like protein
compare
MMP
_RS06175
-1.5
-7.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03445
-1.5
-1.7
methanogenesis marker 17 protein
compare
MMP
_RS08460
-1.5
-2.6
proteasome-activating nucleotidase
compare
MMP
_RS05505
-1.5
-8.8
class IV adenylate cyclase
compare
MMP
_RS03400
-1.5
-4.0
archease
compare
MMP
_RS01365
-1.5
-2.7
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS03145
-1.5
-8.5
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS01220
-1.4
-7.3
hypothetical protein
compare
MMP
_RS08320
-1.4
-5.1
molybdopterin molybdotransferase MoeA
compare
MMP
_RS05430
-1.4
-5.6
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS06120
-1.4
-2.2
UPF0147 family protein
compare
MMP
_RS07580
-1.4
-3.3
DUF356 domain-containing protein
compare
MMP
_RS08105
-1.4
-9.8
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS06215
-1.4
-3.3
30S ribosomal protein S6e
compare
MMP
_RS06230
-1.4
-3.2
helix-turn-helix domain-containing protein
compare
MMP
_RS02280
-1.4
-1.4
DUF211 domain-containing protein
compare
MMP
_RS04870
-1.4
-4.7
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS07600
-1.3
-4.1
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS00515
-1.3
-1.2
DUF655 domain-containing protein
compare
MMP
_RS06200
-1.3
-8.9
M24 family metallopeptidase
compare
MMP
_RS06975
-1.3
-3.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS03155
-1.3
-8.5
precorrin-6A reductase
compare
MMP
_RS02235
-1.3
-8.9
CBS domain-containing protein
compare
MMP
_RS07195
-1.3
-8.4
M20 family metallo-hydrolase
compare
MMP
_RS00120
-1.3
-5.1
LysR family transcriptional regulator
compare
MMP
_RS00320
-1.3
-3.0
class I SAM-dependent methyltransferase
compare
MMP
_RS06930
-1.2
-8.6
MBL fold metallo-hydrolase
compare
MMP
_RS06020
-1.2
-3.9
archaeoflavoprotein AfpA
compare
MMP
_RS03700
-1.2
-6.4
sodium:proton antiporter
compare
MMP
_RS03305
-1.2
-8.0
winged helix-turn-helix domain-containing protein
compare
MMP
_RS03250
-1.2
-2.7
MJ1244 family protein
compare
MMP
_RS07700
-1.2
-6.5
DUF1188 domain-containing protein
compare
MMP
_RS05920
-1.2
-0.9
50S ribosomal protein L37e
compare
MMP
_RS07545
-1.2
-1.3
HTH domain-containing protein
compare
MMP
_RS02345
-1.2
-2.9
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS08435
-1.2
-2.0
Era-like GTP-binding protein
compare
MMP
_RS07955
-1.2
-5.3
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS07200
-1.1
-5.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS02165
-1.1
-6.3
tRNA-dihydrouridine synthase
compare
MMP
_RS03095
-1.1
-7.9
diphthine synthase
compare
MMP
_RS04875
-1.1
-6.6
energy-converting hydrogenase B subunit P
compare
MMP
_RS07385
-1.1
-2.0
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS07960
-1.1
-6.6
sugar phosphate isomerase/epimerase
compare
MMP
_RS05250
-1.1
-1.9
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS07695
-1.1
-5.2
DUF3236 domain-containing protein
compare
MMP
_RS08360
-1.1
-4.1
hypothetical protein
compare
MMP
_RS07535
-1.1
-7.8
4Fe-4S binding protein
compare
MMP
_RS08760
-1.1
-3.1
hypothetical protein
compare
MMP
_RS08445
-1.0
-4.1
DUF2099 family protein
compare
MMP
_RS04850
-1.0
-8.3
UPF0254 family protein
compare
MMP
_RS02190
-1.0
-1.9
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS06865
-1.0
-2.2
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS00475
-1.0
-5.3
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS03110
-1.0
-4.4
glycosyltransferase family 2 protein
compare
MMP
_RS06980
-1.0
-5.3
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS02885
-1.0
-6.7
molybdopterin biosynthesis protein
compare
MMP
_RS01720
-0.9
-1.2
replication factor C large subunit
compare
MMP
_RS00725
-0.9
-4.3
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS01800
-0.9
-3.6
TIGR00303 family protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments