Experiment set4IT082 for Methanococcus maripaludis S2

Compare to:

Formate deepwell autotrophic conditions

200 most important genes:

  gene name fitness t score description  
MMP_RS01020 -5.0 -2.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07345 -4.5 -9.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS05060 -4.2 -23.0 AAA family ATPase compare
MMP_RS05075 -4.1 -27.3 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05100 -4.1 -26.0 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS03315 -4.1 -3.1 ferrous iron transport protein A compare
MMP_RS05090 -4.0 -15.2 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06680 -4.0 -22.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05070 -4.0 -11.2 4Fe-4S dicluster domain-containing protein compare
MMP_RS06685 -4.0 -19.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06705 -4.0 -11.6 formate/nitrite transporter family protein compare
MMP_RS05085 -4.0 -15.6 AAA family ATPase compare
MMP_RS05080 -4.0 -20.5 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00295 -4.0 -4.1 gamma carbonic anhydrase family protein compare
MMP_RS07735 -4.0 -1.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06715 -4.0 -23.0 cache domain-containing protein compare
MMP_RS06700 -3.9 -21.7 hypothetical protein compare
MMP_RS05055 -3.9 -18.7 DUF166 domain-containing protein compare
MMP_RS05095 -3.9 -14.1 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS04615 -3.9 -5.4 PDGLE domain-containing protein compare
MMP_RS04620 -3.8 -16.9 cobalt transporter CbiM compare
MMP_RS06720 -3.8 -14.7 response regulator transcription factor compare
MMP_RS04605 -3.8 -9.6 cobalt ECF transporter T component CbiQ compare
MMP_RS07005 -3.8 -1.5 4Fe-4S binding protein compare
MMP_RS01380 -3.8 -9.4 PHP domain-containing protein compare
MMP_RS06355 -3.7 -4.0 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06730 -3.7 -2.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS06345 -3.6 -15.3 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS05065 -3.6 -7.7 CooT family nickel-binding protein compare
MMP_RS03640 -3.6 -6.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01175 -3.6 -5.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06350 -3.4 -12.1 HesA/MoeB/ThiF family protein compare
MMP_RS03015 -3.4 -16.2 GTP 3' 8-cyclase MoaA compare
MMP_RS07630 -3.3 -3.5 ATP-binding cassette domain-containing protein compare
MMP_RS05500 -3.2 -14.8 2-isopropylmalate synthase compare
MMP_RS05515 -3.2 -9.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07445 -3.2 -11.8 helix-turn-helix domain-containing protein compare
MMP_RS08745 -3.2 -10.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03450 -3.1 -5.1 glycine synthesis protein GlyXS (from data) compare
MMP_RS07730 -3.1 -3.6 pyruvate synthase subunit beta compare
MMP_RS06315 -3.1 -2.4 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05265 -3.0 -4.1 2-isopropylmalate synthase compare
MMP_RS05930 -3.0 -4.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS07365 -3.0 -15.6 2-phosphoglycerate kinase compare
MMP_RS07720 -3.0 -22.4 4Fe-4S binding protein compare
MMP_RS01700 -3.0 -2.2 dihydroxy-acid dehydratase compare
MMP_RS05425 -2.9 -9.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06975 -2.9 -4.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07635 -2.9 -10.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02195 -2.9 -6.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01545 -2.9 -2.5 CBS domain-containing protein compare
MMP_RS03435 -2.7 -3.4 ketol-acid reductoisomerase compare
MMP_RS07525 -2.7 -9.8 4Fe-4S binding protein compare
MMP_RS08790 -2.7 -3.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS06400 -2.7 -3.3 4Fe-4S binding protein compare
MMP_RS06340 -2.7 -10.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01985 -2.6 -8.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01455 -2.6 -13.3 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS06625 -2.6 -3.4 DNA primase compare
MMP_RS06270 -2.6 -8.6 TIGR00300 family protein compare
MMP_RS07575 -2.6 -6.6 RNA ligase partner protein compare
MMP_RS01005 -2.6 -2.9 riboflavin synthase compare
MMP_RS07845 -2.6 -3.7 LL-diaminopimelate aminotransferase compare
MMP_RS01265 -2.5 -6.6 hypothetical protein compare
MMP_RS08720 -2.5 -2.9 4Fe-4S binding protein compare
MMP_RS00290 -2.5 -11.3 hypothetical protein compare
MMP_RS03475 -2.5 -1.4 hypothetical protein compare
MMP_RS07380 -2.5 -3.6 transcription elongation factor Spt5 compare
MMP_RS02900 -2.5 -1.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS09020 -2.4 -2.9 hypothetical protein compare
MMP_RS01500 -2.4 -4.6 CBS domain-containing protein compare
MMP_RS00685 -2.3 -8.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06375 -2.3 -9.5 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS04585 -2.3 -11.9 AIR synthase related protein compare
MMP_RS03035 -2.3 -5.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05555 -2.2 -2.2 DUF4040 domain-containing protein compare
MMP_RS05550 -2.2 -1.3 cation:proton antiporter compare
MMP_RS06630 -2.2 -2.4 UPF0058 family protein compare
MMP_RS04215 -2.2 -9.1 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS05850 -2.2 -8.7 Ldh family oxidoreductase compare
MMP_RS08240 -2.1 -7.6 methanogenesis marker 16 metalloprotein compare
MMP_RS05925 -2.1 -6.5 small nuclear ribonucleoprotein compare
MMP_RS03600 -2.1 -3.6 triose-phosphate isomerase compare
MMP_RS02010 -2.1 -10.2 PHP domain-containing protein compare
MMP_RS02875 -2.1 -13.0 chorismate pyruvate-lyase family protein compare
MMP_RS02800 -2.0 -5.8 nucleotidyltransferase domain-containing protein compare
MMP_RS00300 -2.0 -1.3 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06105 -2.0 -9.0 hydrogenase maturation peptidase HycI compare
MMP_RS04500 -2.0 -15.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00455 -2.0 -11.8 orotate phosphoribosyltransferase-like protein compare
MMP_RS02280 -2.0 -1.8 DUF211 domain-containing protein compare
MMP_RS07185 -2.0 -14.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02135 -2.0 -5.8 DUF5612 domain-containing protein compare
MMP_RS02355 -2.0 -2.7 30S ribosomal protein S27ae compare
MMP_RS08095 -2.0 -9.6 dethiobiotin synthase compare
MMP_RS08645 -2.0 -8.1 UPF0179 family protein compare
MMP_RS01325 -2.0 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS08330 -2.0 -6.1 NADH-quinone oxidoreductase subunit H compare
MMP_RS01610 -2.0 -4.9 hypothetical protein compare
MMP_RS01830 -1.9 -2.3 tRNA-Val compare
MMP_RS08105 -1.9 -9.8 6-carboxyhexanoate--CoA ligase compare
MMP_RS01475 -1.9 -8.9 phosphosulfolactate synthase compare
MMP_RS06295 -1.9 -8.0 methanogenesis marker 14 protein compare
MMP_RS03025 -1.9 -8.0 molybdenum cofactor guanylyltransferase compare
MMP_RS00985 -1.9 -8.2 CDC48 family AAA ATPase compare
MMP_RS05875 -1.9 -4.2 hydroxyethylthiazole kinase compare
MMP_RS07605 -1.9 -5.8 diadenylate cyclase compare
MMP_RS02340 -1.8 -3.2 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03420 -1.8 -4.0 acetolactate synthase small subunit compare
MMP_RS01800 -1.8 -6.1 TIGR00303 family protein compare
MMP_RS07555 -1.8 -1.4 monovalent cation/H+ antiporter subunit E compare
MMP_RS08210 -1.8 -3.1 phosphatidylglycerophosphatase A compare
MMP_RS07645 -1.7 -7.3 aldehyde dehydrogenase family protein compare
MMP_RS06120 -1.7 -3.2 UPF0147 family protein compare
MMP_RS08820 -1.7 -6.4 hypothetical protein compare
MMP_RS03145 -1.7 -9.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00750 -1.7 -3.9 fumarate hydratase compare
MMP_RS00305 -1.7 -2.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS08165 -1.7 -2.9 phosphoglycerate dehydrogenase compare
MMP_RS05920 -1.7 -1.2 50S ribosomal protein L37e compare
MMP_RS00320 -1.7 -3.2 class I SAM-dependent methyltransferase compare
MMP_RS06370 -1.7 -7.0 biotin synthase BioB compare
MMP_RS04780 -1.6 -4.8 ribonuclease P compare
MMP_RS06895 -1.6 -2.3 selenocysteine-specific translation elongation factor compare
MMP_RS06175 -1.6 -9.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS01225 -1.6 -7.6 DUF5379 domain-containing protein compare
MMP_RS08460 -1.6 -3.6 proteasome-activating nucleotidase compare
MMP_RS01795 -1.6 -3.1 methanogenesis marker 6 protein compare
MMP_RS05505 -1.6 -8.9 class IV adenylate cyclase compare
MMP_RS03140 -1.6 -11.2 hypothetical protein compare
MMP_RS08100 -1.6 -9.3 8-amino-7-oxononanoate synthase compare
MMP_RS08635 -1.6 -3.1 UbiA family prenyltransferase compare
MMP_RS07685 -1.6 -8.1 TIGR01212 family radical SAM protein compare
MMP_RS08320 -1.5 -6.6 molybdopterin molybdotransferase MoeA compare
MMP_RS04790 -1.5 -9.4 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS06230 -1.5 -3.0 helix-turn-helix domain-containing protein compare
MMP_RS05540 -1.5 -3.9 hypothetical protein compare
MMP_RS05765 -1.5 -7.8 M42 family metallopeptidase compare
MMP_RS02170 -1.5 -7.8 CBS domain-containing protein compare
MMP_RS06865 -1.5 -2.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS01220 -1.5 -6.8 hypothetical protein compare
MMP_RS00115 -1.5 -10.2 radical SAM protein compare
MMP_RS02240 -1.5 -4.2 methanogenesis marker 7 protein compare
MMP_RS07710 -1.4 -7.9 cell division protein FtsZ compare
MMP_RS00620 -1.4 -9.8 4Fe-4S binding protein compare
MMP_RS06285 -1.4 -3.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07545 -1.4 -1.5 HTH domain-containing protein compare
MMP_RS03305 -1.4 -8.6 winged helix-turn-helix domain-containing protein compare
MMP_RS01365 -1.4 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06930 -1.4 -10.6 MBL fold metallo-hydrolase compare
MMP_RS05430 -1.4 -5.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS07355 -1.4 -1.7 transcription factor S compare
MMP_RS07600 -1.4 -3.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06215 -1.3 -5.1 30S ribosomal protein S6e compare
MMP_RS08435 -1.3 -2.8 Era-like GTP-binding protein compare
MMP_RS05815 -1.3 -3.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS06130 -1.3 -4.1 peptidylprolyl isomerase compare
MMP_RS08650 -1.3 -3.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06395 -1.3 -3.1 ThiF family adenylyltransferase compare
MMP_RS06200 -1.3 -8.9 M24 family metallopeptidase compare
MMP_RS07195 -1.3 -7.5 M20 family metallo-hydrolase compare
MMP_RS08760 -1.3 -3.5 hypothetical protein compare
MMP_RS02345 -1.3 -4.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS04890 -1.2 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02165 -1.2 -7.3 tRNA-dihydrouridine synthase compare
MMP_RS07960 -1.2 -6.4 sugar phosphate isomerase/epimerase compare
MMP_RS00895 -1.2 -4.7 hypothetical protein compare
MMP_RS06885 -1.2 -3.8 50S ribosome-binding GTPase compare
MMP_RS08715 -1.2 -2.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04685 -1.2 -3.9 DUF126 domain-containing protein compare
MMP_RS03400 -1.1 -3.4 archease compare
MMP_RS01865 -1.1 -2.4 GPR1/FUN34/YaaH family transporter compare
MMP_RS06020 -1.1 -3.1 archaeoflavoprotein AfpA compare
MMP_RS06925 -1.1 -2.1 ribonuclease VapC4 compare
MMP_RS04870 -1.1 -4.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS07695 -1.1 -6.1 DUF3236 domain-containing protein compare
MMP_RS03445 -1.1 -1.4 methanogenesis marker 17 protein compare
MMP_RS02235 -1.1 -6.8 CBS domain-containing protein compare
MMP_RS03095 -1.1 -6.3 diphthine synthase compare
MMP_RS03155 -1.1 -5.5 precorrin-6A reductase compare
MMP_RS07700 -1.1 -5.6 DUF1188 domain-containing protein compare
MMP_RS07955 -1.1 -4.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06475 -1.1 -4.3 FAD-dependent oxidoreductase compare
MMP_RS03700 -1.1 -6.9 sodium:proton antiporter compare
MMP_RS07200 -1.1 -5.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS04850 -1.1 -8.9 UPF0254 family protein compare
MMP_RS01755 -1.1 -1.1 DUF2097 domain-containing protein compare
MMP_RS02885 -1.0 -7.9 molybdopterin biosynthesis protein compare
MMP_RS03250 -1.0 -3.2 MJ1244 family protein compare
MMP_RS08445 -1.0 -4.7 DUF2099 family protein compare
MMP_RS04710 -1.0 -1.6 hypothetical protein compare
MMP_RS02190 -1.0 -3.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01335 -1.0 -3.1 prefoldin subunit beta compare
MMP_RS00725 -1.0 -5.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS00475 -1.0 -6.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03110 -1.0 -4.3 glycosyltransferase family 2 protein compare
MMP_RS08370 -1.0 -0.9 cation:proton antiporter subunit C compare
MMP_RS03485 -1.0 -3.2 TIGR00267 family protein compare
MMP_RS07535 -0.9 -6.0 4Fe-4S binding protein compare
MMP_RS04775 -0.9 -2.0 adenosylhomocysteinase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments