Experiment set4IT078 for Methanococcus maripaludis S2

Compare to:

Formate deepwell acetate and vitamin FREE

200 most important genes:

  gene name fitness t score description  
MMP_RS01175 -4.7 -7.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03315 -4.5 -3.2 ferrous iron transport protein A compare
MMP_RS06685 -4.0 -22.0 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06680 -4.0 -21.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01020 -3.7 -2.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06345 -3.6 -17.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06625 -3.5 -6.2 DNA primase compare
MMP_RS01005 -3.5 -2.9 riboflavin synthase compare
MMP_RS06700 -3.4 -19.2 hypothetical protein compare
MMP_RS03015 -3.3 -15.2 GTP 3' 8-cyclase MoaA compare
MMP_RS08790 -3.3 -4.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS06715 -3.2 -21.7 cache domain-containing protein compare
MMP_RS00305 -3.2 -2.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS08745 -3.1 -12.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06720 -3.0 -13.1 response regulator transcription factor compare
MMP_RS06350 -3.0 -14.0 HesA/MoeB/ThiF family protein compare
MMP_RS07005 -3.0 -1.8 4Fe-4S binding protein compare
MMP_RS08460 -2.9 -4.2 proteasome-activating nucleotidase compare
MMP_RS00300 -2.9 -1.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07445 -2.9 -8.9 helix-turn-helix domain-containing protein compare
MMP_RS06355 -2.9 -3.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05515 -2.9 -10.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07635 -2.9 -13.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06705 -2.8 -11.6 formate/nitrite transporter family protein compare
MMP_RS06730 -2.8 -3.4 phosphopantothenate/pantothenate synthetase compare
MMP_RS04605 -2.7 -11.3 cobalt ECF transporter T component CbiQ compare
MMP_RS08820 -2.4 -8.2 hypothetical protein compare
MMP_RS01755 -2.4 -3.2 DUF2097 domain-containing protein compare
MMP_RS04585 -2.3 -11.5 AIR synthase related protein compare
MMP_RS01265 -2.3 -6.6 hypothetical protein compare
MMP_RS07845 -2.3 -7.5 LL-diaminopimelate aminotransferase compare
MMP_RS08645 -2.3 -11.0 UPF0179 family protein compare
MMP_RS06295 -2.3 -10.3 methanogenesis marker 14 protein compare
MMP_RS06895 -2.2 -2.9 selenocysteine-specific translation elongation factor compare
MMP_RS04615 -2.2 -5.7 PDGLE domain-containing protein compare
MMP_RS09020 -2.2 -3.6 hypothetical protein compare
MMP_RS02195 -2.2 -5.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS00895 -2.1 -5.7 hypothetical protein compare
MMP_RS06400 -2.1 -2.4 4Fe-4S binding protein compare
MMP_RS06230 -2.1 -5.8 helix-turn-helix domain-containing protein compare
MMP_RS04620 -2.0 -12.5 cobalt transporter CbiM compare
MMP_RS07545 -2.0 -2.5 HTH domain-containing protein compare
MMP_RS03600 -2.0 -2.6 triose-phosphate isomerase compare
MMP_RS08720 -2.0 -2.1 4Fe-4S binding protein compare
MMP_RS07525 -2.0 -9.2 4Fe-4S binding protein compare
MMP_RS01500 -2.0 -4.1 CBS domain-containing protein compare
MMP_RS03025 -1.9 -6.3 molybdenum cofactor guanylyltransferase compare
MMP_RS02340 -1.9 -4.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01220 -1.9 -10.0 hypothetical protein compare
MMP_RS06630 -1.9 -2.7 UPF0058 family protein compare
MMP_RS08635 -1.9 -2.3 UbiA family prenyltransferase compare
MMP_RS06285 -1.9 -3.8 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08095 -1.8 -9.5 dethiobiotin synthase compare
MMP_RS06370 -1.8 -7.0 biotin synthase BioB compare
MMP_RS08105 -1.8 -9.7 6-carboxyhexanoate--CoA ligase compare
MMP_RS04775 -1.8 -6.3 adenosylhomocysteinase compare
MMP_RS04500 -1.8 -14.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06270 -1.8 -6.0 TIGR00300 family protein compare
MMP_RS02900 -1.7 -1.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07600 -1.7 -5.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01985 -1.7 -6.9 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS03640 -1.7 -7.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06475 -1.7 -6.3 FAD-dependent oxidoreductase compare
MMP_RS01225 -1.7 -6.0 DUF5379 domain-containing protein compare
MMP_RS06340 -1.7 -9.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05920 -1.7 -1.4 50S ribosomal protein L37e compare
MMP_RS01980 -1.7 -13.1 trimeric intracellular cation channel family protein compare
MMP_RS02280 -1.7 -1.9 DUF211 domain-containing protein compare
MMP_RS08100 -1.7 -10.3 8-amino-7-oxononanoate synthase compare
MMP_RS08300 -1.7 -2.3 metal-sulfur cluster assembly factor compare
MMP_RS06105 -1.6 -9.2 hydrogenase maturation peptidase HycI compare
MMP_RS06925 -1.6 -3.2 ribonuclease VapC4 compare
MMP_RS08715 -1.6 -2.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02875 -1.6 -10.5 chorismate pyruvate-lyase family protein compare
MMP_RS02135 -1.6 -7.2 DUF5612 domain-containing protein compare
MMP_RS05540 -1.6 -4.0 hypothetical protein compare
MMP_RS06120 -1.5 -4.1 UPF0147 family protein compare
MMP_RS06885 -1.5 -3.2 50S ribosome-binding GTPase compare
MMP_RS07685 -1.5 -7.9 TIGR01212 family radical SAM protein compare
MMP_RS00515 -1.5 -1.8 DUF655 domain-containing protein compare
MMP_RS06975 -1.5 -4.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07575 -1.5 -5.3 RNA ligase partner protein compare
MMP_RS03400 -1.5 -5.2 archease compare
MMP_RS02355 -1.5 -4.2 30S ribosomal protein S27ae compare
MMP_RS01380 -1.5 -6.3 PHP domain-containing protein compare
MMP_RS06930 -1.5 -10.2 MBL fold metallo-hydrolase compare
MMP_RS00130 -1.5 -2.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS07645 -1.5 -8.4 aldehyde dehydrogenase family protein compare
MMP_RS04890 -1.5 -1.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00295 -1.5 -4.6 gamma carbonic anhydrase family protein compare
MMP_RS00685 -1.5 -4.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05100 -1.4 -12.0 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS08210 -1.4 -3.6 phosphatidylglycerophosphatase A compare
MMP_RS00115 -1.4 -11.0 radical SAM protein compare
MMP_RS03475 -1.4 -1.2 hypothetical protein compare
MMP_RS07195 -1.4 -8.1 M20 family metallo-hydrolase compare
MMP_RS05090 -1.4 -11.2 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05845 -1.4 -3.1 tRNA-intron lyase compare
MMP_RS05430 -1.4 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS04685 -1.4 -4.6 DUF126 domain-containing protein compare
MMP_RS05075 -1.4 -11.6 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05765 -1.4 -8.1 M42 family metallopeptidase compare
MMP_RS02345 -1.3 -3.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS02010 -1.3 -8.8 PHP domain-containing protein compare
MMP_RS01545 -1.3 -2.2 CBS domain-containing protein compare
MMP_RS07630 -1.3 -2.8 ATP-binding cassette domain-containing protein compare
MMP_RS01720 -1.3 -1.3 replication factor C large subunit compare
MMP_RS05095 -1.3 -10.2 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS05085 -1.3 -10.5 AAA family ATPase compare
MMP_RS00290 -1.3 -8.1 hypothetical protein compare
MMP_RS05060 -1.3 -10.1 AAA family ATPase compare
MMP_RS02235 -1.3 -7.8 CBS domain-containing protein compare
MMP_RS02240 -1.3 -3.8 methanogenesis marker 7 protein compare
MMP_RS07605 -1.3 -3.0 diadenylate cyclase compare
MMP_RS05080 -1.2 -10.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS01610 -1.2 -3.1 hypothetical protein compare
MMP_RS07765 -1.2 -7.8 sodium:alanine symporter family protein compare
MMP_RS05055 -1.2 -10.5 DUF166 domain-containing protein compare
MMP_RS06940 -1.2 -3.8 polyprenyl diphosphate synthase compare
MMP_RS02190 -1.2 -2.5 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01365 -1.2 -3.8 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05070 -1.2 -7.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS02800 -1.2 -5.6 nucleotidyltransferase domain-containing protein compare
MMP_RS06020 -1.2 -4.3 archaeoflavoprotein AfpA compare
MMP_RS08650 -1.1 -3.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01800 -1.1 -3.7 TIGR00303 family protein compare
MMP_RS05875 -1.1 -3.2 hydroxyethylthiazole kinase compare
MMP_RS04780 -1.1 -3.0 ribonuclease P compare
MMP_RS00040 -1.1 -6.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00620 -1.1 -7.6 4Fe-4S binding protein compare
MMP_RS07580 -1.1 -3.2 DUF356 domain-containing protein compare
MMP_RS03035 -1.1 -3.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01830 -1.1 -3.0 tRNA-Val compare
MMP_RS06865 -1.1 -2.1 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05510 -1.1 -5.8 Rrf2 family transcriptional regulator compare
MMP_RS06315 -1.1 -1.7 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01325 -1.0 -3.3 dihydroneopterin aldolase family protein compare
MMP_RS01700 -1.0 -1.4 dihydroxy-acid dehydratase compare
MMP_RS01385 -1.0 -1.1 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03580 -1.0 -3.6 signal recognition particle-docking protein FtsY compare
MMP_RS07775 -1.0 -6.2 alanine dehydrogenase compare
MMP_RS08320 -1.0 -6.7 molybdopterin molybdotransferase MoeA compare
MMP_RS06200 -1.0 -7.4 M24 family metallopeptidase compare
MMP_RS03155 -1.0 -5.9 precorrin-6A reductase compare
MMP_RS05065 -1.0 -4.8 CooT family nickel-binding protein compare
MMP_RS02165 -1.0 -6.0 tRNA-dihydrouridine synthase compare
MMP_RS05345 -1.0 -5.0 hypothetical protein compare
MMP_RS01795 -1.0 -2.6 methanogenesis marker 6 protein compare
MMP_RS03250 -0.9 -2.6 MJ1244 family protein compare
MMP_RS03700 -0.9 -4.8 sodium:proton antiporter compare
MMP_RS07200 -0.9 -5.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05245 -0.9 -6.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS00695 -0.9 -1.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01250 -0.9 -4.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07390 -0.9 -2.9 cell division protein FtsZ compare
MMP_RS03205 -0.9 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS05265 -0.9 -2.9 2-isopropylmalate synthase compare
MMP_RS00110 -0.9 -2.4 hypothetical protein compare
MMP_RS07700 -0.8 -6.3 DUF1188 domain-containing protein compare
MMP_RS00915 -0.8 -4.9 DUF116 domain-containing protein compare
MMP_RS06215 -0.8 -3.7 30S ribosomal protein S6e compare
MMP_RS00120 -0.8 -4.7 LysR family transcriptional regulator compare
MMP_RS05550 -0.8 -0.9 cation:proton antiporter compare
MMP_RS07730 -0.8 -1.7 pyruvate synthase subunit beta compare
MMP_RS02130 -0.8 -3.3 zinc metalloprotease HtpX compare
MMP_RS03960 -0.8 -1.1 hypothetical protein compare
MMP_RS07380 -0.8 -2.7 transcription elongation factor Spt5 compare
MMP_RS00320 -0.8 -2.4 class I SAM-dependent methyltransferase compare
MMP_RS07425 -0.8 -4.9 GTP-binding protein compare
MMP_RS08070 -0.8 -4.2 DUF2096 domain-containing protein compare
MMP_RS08440 -0.8 -2.9 cell division protein SepF compare
MMP_RS05850 -0.8 -4.1 Ldh family oxidoreductase compare
MMP_RS00050 -0.8 -5.0 AarF/UbiB family protein compare
MMP_RS03305 -0.8 -6.2 winged helix-turn-helix domain-containing protein compare
MMP_RS07720 -0.8 -6.5 4Fe-4S binding protein compare
MMP_RS04870 -0.8 -3.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS06110 -0.8 -3.0 ATP-dependent protease LonB compare
MMP_RS08690 -0.8 -5.4 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS05440 -0.8 -5.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS03435 -0.8 -1.5 ketol-acid reductoisomerase compare
MMP_RS00310 -0.8 -4.7 CBS domain-containing protein compare
MMP_RS01445 -0.8 -4.8 hypothetical protein compare
MMP_RS03095 -0.8 -4.4 diphthine synthase compare
MMP_RS08435 -0.7 -1.5 Era-like GTP-binding protein compare
MMP_RS01475 -0.7 -3.8 phosphosulfolactate synthase compare
MMP_RS05545 -0.7 -3.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS04710 -0.7 -1.5 hypothetical protein compare
MMP_RS05445 -0.7 -4.7 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS08725 -0.7 -0.9 Ni/Fe hydrogenase subunit alpha compare
MMP_RS08445 -0.7 -2.3 DUF2099 family protein compare
MMP_RS00985 -0.7 -3.0 CDC48 family AAA ATPase compare
MMP_RS07735 -0.7 -1.1 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05815 -0.7 -2.3 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01725 -0.7 -2.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS00475 -0.7 -4.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00720 -0.7 -4.7 metal-dependent hydrolase compare
MMP_RS01840 -0.7 -5.5 TIGR00289 family protein compare
MMP_RS07755 -0.7 -1.1 DUF555 domain-containing protein compare
MMP_RS00725 -0.7 -4.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS02885 -0.6 -5.4 molybdopterin biosynthesis protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 casamino acids across organisms