Experiment set4IT075 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Leucine carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_3115 +2.9 17.7 RNA polymerase sigma factor RpoS compare
Pf1N1B4_407 +2.1 3.5 ADP-ribosylglycohydrolase YegU (EC 3.2.-.-) compare
Pf1N1B4_969 +1.8 17.4 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf1N1B4_3911 +1.7 6.4 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_971 +1.7 14.7 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf1N1B4_973 +1.7 15.2 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf1N1B4_972 +1.7 15.5 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf1N1B4_970 +1.6 11.8 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf1N1B4_688 +1.5 2.4 FIG00955483: hypothetical protein compare
Pf1N1B4_1180 +1.5 3.9 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_3191 +1.5 2.7 FIG00953505: hypothetical protein compare
Pf1N1B4_290 +1.5 13.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_262 +1.5 13.3 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf1N1B4_288 +1.4 9.6 FIG00958794: hypothetical protein compare
Pf1N1B4_3991 +1.4 2.4 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf1N1B4_1115 +1.4 10.2 Dna binding response regulator PrrA (RegA) compare
Pf1N1B4_291 +1.4 7.6 Major outer membrane lipoprotein I compare
Pf1N1B4_1334 +1.3 2.0 FIG00955840: hypothetical protein compare
Pf1N1B4_2114 +1.3 8.0 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf1N1B4_3507 +1.3 10.7 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf1N1B4_2637 +1.3 6.6 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
Pf1N1B4_5763 +1.3 2.7 Nitric oxide reductase activation protein NorQ compare
Pf1N1B4_4855 +1.2 3.1 Response regulator compare
Pf1N1B4_1475 +1.2 7.1 FIG00962376: hypothetical protein compare
Pf1N1B4_2008 +1.2 8.8 Phosphogluconate repressor HexR, RpiR family compare
Pf1N1B4_4937 +1.2 4.1 Two-component hybrid sensor and regulator compare
Pf1N1B4_386 +1.2 8.4 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) conserved
Pf1N1B4_287 +1.2 6.4 Possible periplasmic thiredoxin compare
Pf1N1B4_4043 +1.2 3.1 Type II and III secretion system family protein compare
Pf1N1B4_1116 +1.2 8.9 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf1N1B4_1335 +1.1 5.9 Copper metallochaperone, bacterial analog of Cox17 protein compare
Pf1N1B4_731 +1.1 3.2 Scaffold protein for [4Fe-4S] cluster assembly ApbC, MRP-like compare
Pf1N1B4_286 +1.1 7.9 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf1N1B4_4366 +1.1 2.5 hypothetical protein compare
Pf1N1B4_2736 +1.1 2.4 ATP-dependent RNA helicase PA3950 compare
Pf1N1B4_3111 +1.1 1.7 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
Pf1N1B4_1489 +1.1 7.7 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) conserved
Pf1N1B4_1886 +1.1 4.4 FIG00956005: hypothetical protein compare
Pf1N1B4_1466 +1.1 4.7 hypothetical protein compare
Pf1N1B4_292 +1.1 10.1 ErfK/YbiS/YcfS/YnhG family protein compare
Pf1N1B4_3435 +1.1 2.1 ABC transporter for L-Arginine and L-Citrulline, ATPase component (from data) compare
Pf1N1B4_4482 +1.1 2.3 FIG146518: Zn-dependent hydrolases, including glyoxylases compare
Pf1N1B4_4736 +1.0 2.5 Fap amyloid fibril minor component compare
Pf1N1B4_2382 +1.0 7.9 ATP-dependent RNA helicase RhlE compare
Pf1N1B4_5820 +1.0 2.5 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_1069 +1.0 5.2 YrbA protein compare
Pf1N1B4_4521 +1.0 2.8 Probable transmembrane protein compare
Pf1N1B4_3501 +1.0 5.1 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_1465 +1.0 8.3 Carbamoyltransferase in large core OS assembly cluster compare
Pf1N1B4_345 +1.0 2.1 Integration host factor beta subunit compare
Pf1N1B4_6041 +1.0 1.6 Carbon storage regulator compare
Pf1N1B4_4858 +1.0 4.0 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_2281 +1.0 3.1 Predicted integral membrane protein compare
Pf1N1B4_3591 +1.0 5.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41) compare
Pf1N1B4_387 +1.0 1.8 hypothetical protein compare
Pf1N1B4_2456 +1.0 2.3 Sarcosine oxidase delta subunit (EC 1.5.3.1) compare
Pf1N1B4_5105 +0.9 1.9 Peptide ABC transporter, ATP-binding protein compare
Pf1N1B4_2724 +0.9 5.3 Transcriptional regulator, AsnC family compare
Pf1N1B4_4582 +0.9 1.8 hypothetical protein compare
Pf1N1B4_3229 +0.9 5.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_1441 +0.9 6.8 Putative esterase, FIGfam005057 compare
Pf1N1B4_1469 +0.9 8.3 Heptose kinase WapQ, eukaryotic type compare
Pf1N1B4_5187 +0.9 0.8 5S RNA compare
Pf1N1B4_5146 +0.9 1.5 Chromosome initiation inhibitor compare
Pf1N1B4_4429 +0.9 1.5 No significant database matches compare
Pf1N1B4_3514 +0.9 6.9 Sensor histidine kinase/response regulator compare
Pf1N1B4_5109 +0.9 1.7 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Pf1N1B4_5801 +0.9 2.3 hypothetical protein compare
Pf1N1B4_4349 +0.9 2.4 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
Pf1N1B4_563 +0.9 3.0 RNA polymerase sigma-70 factor compare
Pf1N1B4_1888 +0.9 3.8 Glutamate-aspartate carrier protein compare
Pf1N1B4_998 +0.9 3.5 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_1042 +0.9 2.0 Dihydroneopterin triphosphate epimerase compare
Pf1N1B4_4874 +0.9 1.6 hypothetical protein compare
Pf1N1B4_2314 +0.9 2.0 FIG028932: hypothetical protein compare
Pf1N1B4_3722 +0.9 2.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_5871 +0.9 2.1 FIG00963848: hypothetical protein compare
Pf1N1B4_5056 +0.9 2.6 Uncharacterized glutathione S-transferase-like protein compare
Pf1N1B4_2178 +0.9 1.3 Regulator of nucleoside diphosphate kinase compare
Pf1N1B4_1885 +0.9 4.5 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf1N1B4_650 +0.9 2.7 FIG001943: hypothetical protein YajQ compare
Pf1N1B4_3588 +0.9 1.9 N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) compare
Pf1N1B4_4402 +0.9 1.4 SoxH protein, homolog compare
Pf1N1B4_1403 +0.9 4.4 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_2352 +0.8 4.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf1N1B4_5149 +0.8 2.9 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf1N1B4_4331 +0.8 1.7 Transporter, LysE family compare
Pf1N1B4_3625 +0.8 2.2 Flagellar synthesis regulator FleN compare
Pf1N1B4_3785 +0.8 1.1 FOG: Ankyrin repeat compare
Pf1N1B4_574 +0.8 2.4 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf1N1B4_4552 +0.8 2.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
Pf1N1B4_1154 +0.8 2.4 FIG00957702: hypothetical protein compare
Pf1N1B4_2072 +0.8 2.7 Phosphoprotein phosphatase PppA compare
Pf1N1B4_5435 +0.8 1.3 hypothetical protein compare
Pf1N1B4_3826 +0.8 4.9 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf1N1B4_2975 +0.8 1.3 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_5803 +0.8 2.7 Catechol 1,2-dioxygenase (EC 1.13.11.1) compare
Pf1N1B4_5930 +0.8 4.0 Exopolysaccharide production protein ExoZ compare
Pf1N1B4_3549 +0.8 1.6 YciL protein compare
Pf1N1B4_3525 +0.8 1.5 hydrolase, alpha/beta fold family compare
Pf1N1B4_2247 +0.8 1.7 FMN reductase (EC 1.5.1.29) compare
Pf1N1B4_4749 +0.8 2.6 ABC transporter ATP-binding protein uup compare
Pf1N1B4_1570 +0.8 2.7 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
Pf1N1B4_2544 +0.8 4.8 Phosphoglycolate phosphatase (EC 3.1.3.18) compare
Pf1N1B4_3485 +0.8 1.5 hypothetical protein compare
Pf1N1B4_3831 +0.8 3.6 CmpX compare
Pf1N1B4_3050 +0.8 2.4 FIG00958830: hypothetical protein compare
Pf1N1B4_656 +0.8 4.8 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
Pf1N1B4_4304 +0.8 1.6 hypothetical protein compare
Pf1N1B4_4823 +0.8 2.1 Paraquat-inducible protein A compare
Pf1N1B4_2154 +0.8 2.0 hypothetical protein compare
Pf1N1B4_2356 +0.8 2.2 hypothetical protein compare
Pf1N1B4_3794 +0.8 2.0 hypothetical protein compare
Pf1N1B4_547 +0.7 2.6 3-phosphoglycerate kinase compare
Pf1N1B4_5703 +0.7 2.0 FIG00961921: hypothetical protein compare
Pf1N1B4_4333 +0.7 1.4 hypothetical protein compare
Pf1N1B4_5439 +0.7 1.7 hypothetical protein compare
Pf1N1B4_2971 +0.7 2.8 hypothetical protein compare
Pf1N1B4_5022 +0.7 2.0 hypothetical protein compare
Pf1N1B4_4812 +0.7 2.0 Site-specific recombinase, phage integrase family compare
Pf1N1B4_54 +0.7 2.4 Cyclohexadienyl dehydratase (EC 4.2.1.51)(EC 4.2.1.91) compare
Pf1N1B4_5509 +0.7 1.3 hypothetical protein compare
Pf1N1B4_3783 +0.7 2.2 FIG00958237: hypothetical protein compare
Pf1N1B4_5853 +0.7 1.3 Glutamine synthetase (EC 6.3.1.2), putative compare
Pf1N1B4_3590 +0.7 3.8 hypothetical protein compare
Pf1N1B4_2948 +0.7 1.7 FIG00954698: hypothetical protein compare
Pf1N1B4_2791 +0.7 1.4 Putative inner membrane protein (Fragment) compare
Pf1N1B4_4472 +0.7 1.2 Transcriptional regulator, ArsR family compare
Pf1N1B4_4700 +0.7 0.9 FIG00956898: hypothetical protein compare
Pf1N1B4_5831 +0.7 2.4 SAM-dependent methyltransferases compare
Pf1N1B4_2357 +0.7 4.6 type IV pilus biogenesis protein PilJ compare
Pf1N1B4_5659 +0.7 5.3 NfuA Fe-S protein maturation compare
Pf1N1B4_5383 +0.7 4.6 hypothetical protein compare
Pf1N1B4_1632 +0.7 3.0 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf1N1B4_4051 +0.7 2.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf1N1B4_4721 +0.7 1.6 Nuclease inhibitor compare
Pf1N1B4_1457 +0.7 3.9 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_218 +0.7 3.3 Periplasmic binding protein compare
Pf1N1B4_1870 +0.7 1.9 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_1612 +0.7 1.5 FIG00955429: hypothetical protein compare
Pf1N1B4_901 +0.7 2.1 hypothetical protein compare
Pf1N1B4_164 +0.7 1.3 ADP-ribosylglycohydrolase family protein compare
Pf1N1B4_1889 +0.7 5.6 Fused spore maturation proteins A and B compare
Pf1N1B4_3119 +0.7 1.5 Holin compare
Pf1N1B4_338 +0.7 1.8 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_1462 +0.7 5.5 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
Pf1N1B4_2224 +0.7 1.3 FIG00953390: hypothetical protein compare
Pf1N1B4_2169 +0.7 1.3 FIG00953808: hypothetical protein compare
Pf1N1B4_3829 +0.7 5.0 Magnesium and cobalt transport protein CorA compare
Pf1N1B4_3005 +0.7 4.8 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf1N1B4_285 +0.7 3.2 5'-nucleotidase (EC 3.1.3.5) compare
Pf1N1B4_1370 +0.7 1.0 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf1N1B4_5242 +0.7 1.2 hypothetical protein compare
Pf1N1B4_5159 +0.7 2.0 Cellulose synthase operon protein C compare
Pf1N1B4_932 +0.7 0.8 FIG00963370: hypothetical protein compare
Pf1N1B4_4762 +0.7 1.8 hypothetical protein compare
Pf1N1B4_272 +0.6 2.1 Transcriptional regulator, LysR family compare
Pf1N1B4_4768 +0.6 2.4 hypothetical protein compare
Pf1N1B4_723 +0.6 4.7 two-component system sensor protein compare
Pf1N1B4_4819 +0.6 2.3 Multidrug resistance protein B compare
Pf1N1B4_3372 +0.6 1.9 FIG00962464: hypothetical protein compare
Pf1N1B4_4220 +0.6 1.4 Maebl compare
Pf1N1B4_157 +0.6 1.3 ThiJ/PfpI family protein compare
Pf1N1B4_4133 +0.6 2.0 Mobile element protein compare
Pf1N1B4_5607 +0.6 1.6 C4-dicarboxylate transport protein compare
Pf1N1B4_687 +0.6 2.4 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) compare
Pf1N1B4_4950 +0.6 1.4 formate dehydrogenase formation protein FdhE compare
Pf1N1B4_2177 +0.6 0.8 FIG00953342: hypothetical protein compare
Pf1N1B4_5112 +0.6 1.4 sucrose ABC transporter, substrate-binding component (from data) compare
Pf1N1B4_5382 +0.6 2.1 hypothetical protein compare
Pf1N1B4_4281 +0.6 2.3 Glyceraldehyde-3-phosphate ketol-isomerase (EC 5.3.1.1) compare
Pf1N1B4_4560 +0.6 1.2 Transcriptional regulator, MerR family compare
Pf1N1B4_1869 +0.6 3.5 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf1N1B4_5907 +0.6 2.6 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Pf1N1B4_2096 +0.6 1.0 Protein serine/threonine phosphatase PrpC, regulation of stationary phase compare
Pf1N1B4_1820 +0.6 5.0 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf1N1B4_208 +0.6 2.0 Two-component system response regulator QseB compare
Pf1N1B4_4604 +0.6 1.8 FMN reductase, NADPH-dependent compare
Pf1N1B4_5151 +0.6 1.2 FIG002283: Isochorismatase family protein compare
Pf1N1B4_3389 +0.6 3.3 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf1N1B4_1140 +0.6 2.3 Iron-uptake factor PiuC compare
Pf1N1B4_2413 +0.6 1.7 Permeases of the major facilitator superfamily compare
Pf1N1B4_5460 +0.6 1.8 TolA protein compare
Pf1N1B4_1610 +0.6 2.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_1472 +0.6 1.2 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_749 +0.6 1.1 hypothetical protein compare
Pf1N1B4_4755 +0.6 1.2 ribosomal protein S6 glutaminyl transferase related protein compare
Pf1N1B4_3627 +0.6 1.0 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_2184 +0.6 3.4 Autolysis response regulater LytR compare
Pf1N1B4_1468 +0.6 5.0 InaA protein compare
Pf1N1B4_5433 +0.6 1.7 hypothetical protein compare
Pf1N1B4_4650 +0.6 2.1 Aspartate racemase (EC 5.1.1.13) compare
Pf1N1B4_5779 +0.6 1.1 Nitrous oxide reductase maturation protein NosF (ATPase) compare
Pf1N1B4_3540 +0.6 2.2 Metal-dependent phosphohydrolase, HD subdomain compare
Pf1N1B4_3147 +0.6 3.7 Putative NADPH-quinone reductase (modulator of drug activity B) compare
Pf1N1B4_441 +0.6 1.4 hypothetical protein compare
Pf1N1B4_491 +0.6 2.0 Type II/IV secretion system secretin RcpA/CpaC, associated with Flp pilus assembly compare
Pf1N1B4_206 +0.6 2.4 hypothetical protein compare
Pf1N1B4_4460 +0.6 1.1 Cytochrome b561 compare
Pf1N1B4_5919 +0.6 2.0 Signal transduction response regulator / Tetratricopeptide repeat-containing protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Leucine in Pseudomonas fluorescens FW300-N1B4

For carbon source L-Leucine across organisms