Experiment set4IT073 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Valine carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.2 -4.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_3697 -4.1 -8.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_4481 -3.9 -3.7 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_1067 -3.7 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1307 -3.6 -2.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_2880 -3.6 -12.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1408 -3.6 -4.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_2550 -3.6 -5.8 Lipoate-protein ligase A conserved
Pf1N1B4_4790 -3.4 -6.0 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) conserved
Pf1N1B4_1831 -3.4 -9.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_1624 -3.3 -8.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_5666 -3.3 -4.3 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_4478 -3.3 -4.2 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_2208 -3.3 -7.7 Polyphosphate kinase (EC 2.7.4.1) compare
Pf1N1B4_3820 -3.2 -8.5 2-methylcitrate synthase (EC 2.3.3.5) conserved
Pf1N1B4_2112 -3.2 -14.3 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_2545 -3.2 -13.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1830 -3.1 -10.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2548 -3.1 -6.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2303 -3.1 -14.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_2526 -3.0 -15.9 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_15 -3.0 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2009 -3.0 -4.5 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1035 -3.0 -6.0 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) compare
Pf1N1B4_3506 -3.0 -7.5 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1626 -2.9 -7.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_2284 -2.9 -5.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_3038 -2.8 -5.7 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_2549 -2.8 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2878 -2.8 -8.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_1315 -2.8 -8.7 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_742 -2.8 -6.9 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_5665 -2.7 -5.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2384 -2.7 -12.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_4476 -2.7 -4.2 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf1N1B4_1230 -2.7 -4.7 Transcriptional regulator, LysR family compare
Pf1N1B4_2858 -2.7 -11.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1229 -2.7 -8.3 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) conserved
Pf1N1B4_5926 -2.6 -12.4 hypothetical protein compare
Pf1N1B4_4477 -2.6 -3.7 Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) compare
Pf1N1B4_5924 -2.6 -9.5 hypothetical protein compare
Pf1N1B4_2380 -2.6 -13.3 Cytochrome B561 compare
Pf1N1B4_3821 -2.6 -6.1 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf1N1B4_3812 -2.6 -9.6 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_4480 -2.6 -3.1 Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) compare
Pf1N1B4_847 -2.6 -9.0 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_2272 -2.6 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_12 -2.6 -6.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_2338 -2.6 -8.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1228 -2.5 -4.0 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) compare
Pf1N1B4_2010 -2.5 -6.8 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_1627 -2.5 -4.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_1434 -2.5 -7.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_5927 -2.5 -18.1 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_1617 -2.5 -8.6 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_2491 -2.5 -4.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_1668 -2.5 -6.3 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_2488 -2.4 -8.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_2282 -2.4 -9.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2381 -2.4 -10.4 Protein yceI precursor compare
Pf1N1B4_2487 -2.4 -7.8 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_3819 -2.4 -4.7 Methylisocitrate lyase (EC 4.1.3.30) compare
Pf1N1B4_4065 -2.4 -7.5 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_2011 -2.3 -8.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_5925 -2.3 -9.5 hypothetical protein compare
Pf1N1B4_1565 -2.3 -5.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_350 -2.3 -7.6 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_762 -2.3 -6.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2337 -2.2 -5.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2377 -2.2 -6.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_1057 -2.1 -3.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_58 -2.1 -6.3 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_5619 -2.1 -5.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_3985 -2.1 -3.2 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_1625 -2.0 -4.3 FIG00956267: hypothetical protein compare
Pf1N1B4_3990 -2.0 -3.8 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_652 -2.0 -9.7 Sensory box histidine kinase compare
Pf1N1B4_327 -2.0 -2.1 hypothetical protein compare
Pf1N1B4_898 -2.0 -8.3 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf1N1B4_5224 -2.0 -3.7 tRNA-Arg-CCT compare
Pf1N1B4_3917 -1.9 -4.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_1153 -1.9 -4.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_4479 -1.9 -3.6 Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) compare
Pf1N1B4_2493 -1.9 -3.1 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_1906 -1.9 -4.3 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1113 -1.8 -6.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_2859 -1.8 -11.5 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1614 -1.8 -2.5 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_4758 -1.7 -3.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_3984 -1.7 -5.1 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) conserved
Pf1N1B4_3720 -1.7 -7.6 Long-chain fatty acid transport protein compare
Pf1N1B4_3081 -1.7 -14.4 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_3888 -1.7 -9.5 Aconitate hydratase (EC 4.2.1.3) compare
Pf1N1B4_27 -1.7 -4.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_4055 -1.6 -6.8 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf1N1B4_2490 -1.6 -5.5 Biotin synthesis protein BioC compare
Pf1N1B4_2489 -1.6 -5.5 Biotin synthesis protein BioH compare
Pf1N1B4_1837 -1.6 -2.7 Osmotically inducible protein C compare
Pf1N1B4_1317 -1.6 -3.5 Sensor histidine kinase/response regulator compare
Pf1N1B4_1566 -1.5 -6.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_22 -1.5 -7.1 Transcriptional regulator, TetR family compare
Pf1N1B4_3986 -1.5 -4.0 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) compare
Pf1N1B4_2273 -1.5 -4.8 hypothetical protein compare
Pf1N1B4_74 -1.4 -2.6 hypothetical protein compare
Pf1N1B4_4446 -1.4 -2.5 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_257 -1.4 -5.5 sensor histidine kinase/response regulator compare
Pf1N1B4_4212 -1.4 -2.5 Gfa-like protein compare
Pf1N1B4_3152 -1.4 -5.2 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_2283 -1.4 -2.1 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_4643 -1.3 -7.3 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form compare
Pf1N1B4_2339 -1.3 -2.3 COG1872 compare
Pf1N1B4_2280 -1.3 -6.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_2169 -1.3 -2.2 FIG00953808: hypothetical protein compare
Pf1N1B4_3368 -1.3 -2.1 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_2547 -1.3 -3.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_3866 -1.3 -2.3 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Pf1N1B4_3818 -1.3 -2.2 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf1N1B4_175 -1.3 -2.6 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_2004 -1.2 -2.1 putative membrane protein compare
Pf1N1B4_3501 -1.2 -4.7 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_2527 -1.2 -7.0 ApaG protein compare
Pf1N1B4_3833 -1.2 -5.7 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_2486 -1.2 -1.4 hypothetical protein compare
Pf1N1B4_5720 -1.2 -2.3 hypothetical protein compare
Pf1N1B4_2239 -1.2 -4.1 FIG00953395: hypothetical protein compare
Pf1N1B4_5446 -1.2 -3.2 hypothetical protein compare
Pf1N1B4_4134 -1.1 -2.5 Na+ driven multidrug efflux pump compare
Pf1N1B4_3312 -1.1 -3.4 Tricarboxylate transport protein TctB compare
Pf1N1B4_3143 -1.1 -2.4 RecA protein compare
Pf1N1B4_2143 -1.1 -7.5 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_5239 -1.1 -2.8 hypothetical protein compare
Pf1N1B4_2105 -1.1 -1.9 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_2874 -1.1 -2.3 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_5659 -1.1 -7.2 NfuA Fe-S protein maturation compare
Pf1N1B4_3508 -1.1 -1.7 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_2939 -1.1 -4.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf1N1B4_373 -1.1 -2.5 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC compare
Pf1N1B4_1691 -1.0 -1.5 hypothetical protein compare
Pf1N1B4_4448 -1.0 -1.9 COGs COG2343 compare
Pf1N1B4_3766 -1.0 -4.5 Uricase (urate oxidase) (EC 1.7.3.3) compare
Pf1N1B4_188 -1.0 -1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_5133 -1.0 -2.8 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_3142 -1.0 -2.9 C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS compare
Pf1N1B4_2478 -1.0 -5.3 Malate synthase G (EC 2.3.3.9) compare
Pf1N1B4_1339 -1.0 -1.9 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
Pf1N1B4_4024 -1.0 -1.9 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_3356 -1.0 -1.3 Cyclic nucleotide-binding protein compare
Pf1N1B4_5294 -1.0 -1.8 hypothetical protein compare
Pf1N1B4_3518 -1.0 -1.9 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_4107 -1.0 -2.1 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_2168 -1.0 -5.4 FIG004064: hypothetical protein compare
Pf1N1B4_2807 -1.0 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf1N1B4_3168 -1.0 -2.2 AmpG permease compare
Pf1N1B4_1545 -1.0 -5.7 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf1N1B4_629 -1.0 -2.3 Queuosine Biosynthesis QueE Radical SAM compare
Pf1N1B4_5554 -1.0 -2.3 hypothetical protein compare
Pf1N1B4_2891 -0.9 -2.9 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf1N1B4_4054 -0.9 -3.7 ATP-dependent Clp protease adaptor protein ClpS compare
Pf1N1B4_4833 -0.9 -2.5 DNA-binding response regulator, LuxR family compare
Pf1N1B4_1492 -0.9 -1.1 FIG00959437: hypothetical protein compare
Pf1N1B4_76 -0.9 -2.2 ATP binding protein compare
Pf1N1B4_1561 -0.9 -2.5 FIG00954300: hypothetical protein compare
Pf1N1B4_3662 -0.9 -2.8 hypothetical protein compare
Pf1N1B4_1590 -0.9 -3.5 Histidine utilization repressor compare
Pf1N1B4_617 -0.9 -1.6 Carbamate kinase (EC 2.7.2.2) compare
Pf1N1B4_4506 -0.9 -2.0 Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) compare
Pf1N1B4_4318 -0.9 -2.1 hypothetical protein compare
Pf1N1B4_5476 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_1540 -0.9 -2.5 Type IV pilus biogenesis protein PilP compare
Pf1N1B4_2877 -0.9 -4.2 Glycosyltransferase compare
Pf1N1B4_5817 -0.9 -1.2 Decarboxylase family protein compare
Pf1N1B4_1619 -0.9 -5.3 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf1N1B4_3454 -0.9 -3.4 Mg/Co/Ni transporter MgtE / CBS domain compare
Pf1N1B4_1835 -0.9 -3.3 hypothetical protein compare
Pf1N1B4_1891 -0.9 -1.3 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf1N1B4_1234 -0.8 -2.8 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_5737 -0.8 -2.1 Nitrate/nitrite transporter compare
Pf1N1B4_5799 -0.8 -2.1 Benzoate 1,2-dioxygenase beta subunit (EC 1.14.12.10) compare
Pf1N1B4_419 -0.8 -1.5 Transcriptional regulator, TetR family compare
Pf1N1B4_2453 -0.8 -0.8 hypothetical protein compare
Pf1N1B4_4972 -0.8 -1.8 CELL PROCESSES; Adaptation; adaptations, atypical conditions compare
Pf1N1B4_5255 -0.8 -2.0 hypothetical protein compare
Pf1N1B4_5425 -0.8 -1.7 DNA-binding protein HU-beta compare
Pf1N1B4_6037 -0.8 -1.8 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_1816 -0.8 -4.2 Glutaryl-CoA dehydrogenase (EC 1.3.99.7) compare
Pf1N1B4_3939 -0.8 -2.2 FIG00953489: hypothetical protein compare
Pf1N1B4_165 -0.8 -1.9 FIG00638667: hypothetical protein compare
Pf1N1B4_2240 -0.8 -2.5 Transcriptional regulator, AsnC family compare
Pf1N1B4_1 -0.8 -1.6 Colicin V production protein compare
Pf1N1B4_348 -0.8 -2.5 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_4437 -0.8 -2.1 hypothetical protein compare
Pf1N1B4_5498 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_3987 -0.8 -3.1 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf1N1B4_4668 -0.8 -2.1 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_1971 -0.8 -2.5 SAM-dependent methyltransferases compare
Pf1N1B4_2503 -0.8 -5.3 Coenzyme PQQ synthesis protein F compare
Pf1N1B4_5311 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_4103 -0.8 -1.4 Flagellar synthesis regulator FleN compare
Pf1N1B4_758 -0.8 -2.3 Bacterioferritin compare
Pf1N1B4_202 -0.8 -2.1 ABC transporter in pyoverdin gene cluster, permease component compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source L-Valine in Pseudomonas fluorescens FW300-N1B4

For carbon source L-Valine across organisms