Experiment set4IT072 for Acidovorax sp. GW101-3H11

Compare to:

L-Serine nitrogen source

200 most important genes:

  gene name fitness t score description  
Ac3H11_771 -6.4 -6.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Ac3H11_772 -6.0 -4.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Ac3H11_2452 -5.9 -7.0 O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) (from data) compare
Ac3H11_769 -5.8 -4.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Ac3H11_4401 -5.3 -6.4 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) compare
Ac3H11_4277 -5.2 -20.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Ac3H11_1525 -5.2 -21.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Ac3H11_3553 -5.2 -20.3 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) compare
Ac3H11_767 -4.8 -20.3 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Ac3H11_3045 -4.8 -19.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Ac3H11_1533 -4.7 -13.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Ac3H11_29 -4.7 -13.2 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Ac3H11_1528 -4.7 -24.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Ac3H11_2345 -4.6 -18.0 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) compare
Ac3H11_1535 -4.6 -13.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Ac3H11_4044 -4.6 -11.0 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Ac3H11_1527 -4.5 -10.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Ac3H11_3449 -4.3 -8.3 Shikimate kinase I (EC 2.7.1.71) compare
Ac3H11_2574 -4.3 -9.7 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Ac3H11_2925 -4.3 -8.6 Chorismate synthase (EC 4.2.3.5) compare
Ac3H11_4711 -4.3 -5.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Ac3H11_4710 -4.2 -23.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Ac3H11_1534 -4.2 -19.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Ac3H11_2344 -4.1 -9.4 Transcriptional activator MetR compare
Ac3H11_268 -4.0 -4.7 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Ac3H11_4278 -3.9 -14.5 Methionine biosynthesis protein MetW compare
Ac3H11_4092 -3.9 -2.6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
Ac3H11_929 -3.7 -15.3 L-serine ammonia-lyase (EC 4.3.1.17) (from data) conserved
Ac3H11_525 -3.7 -10.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Ac3H11_3341 -3.7 -2.5 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
Ac3H11_4771 -3.7 -12.0 Glutamate 5-kinase (EC 2.7.2.11) compare
Ac3H11_4432 -3.6 -10.3 Nitrogen regulation protein NR(I) compare
Ac3H11_4091 -3.6 -7.5 Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) compare
Ac3H11_4034 -3.5 -11.0 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Ac3H11_4705 -3.3 -9.0 3-dehydroquinate synthase (EC 4.2.3.4) compare
Ac3H11_2608 -3.2 -5.1 Amidophosphoribosyltransferase (EC 2.4.2.14) compare
Ac3H11_2027 -3.2 -16.4 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) compare
Ac3H11_4095 -3.1 -15.9 Nitrogen regulation protein NR(I) compare
Ac3H11_3630 -3.1 -4.3 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Ac3H11_4093 -3.1 -17.0 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
Ac3H11_456 -2.9 -2.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Ac3H11_3860 -2.7 -8.7 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Ac3H11_2464 -2.7 -6.4 ATPase component BioM of energizing module of biotin ECF transporter compare
Ac3H11_376 -2.7 -1.7 DNA-binding protein HU-beta compare
Ac3H11_2575 -2.7 -4.9 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) compare
Ac3H11_362 -2.7 -10.7 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I compare
Ac3H11_727 -2.5 -11.5 RNA polymerase sigma-54 factor RpoN compare
Ac3H11_683 -2.4 -1.9 HPr kinase/phosphorylase (EC 2.7.1.-) (EC 2.7.4.-) compare
Ac3H11_4236 -2.4 -7.5 Homoserine dehydrogenase (EC 1.1.1.3) compare
Ac3H11_537 -2.4 -16.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Ac3H11_2076 -2.3 -4.4 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Ac3H11_2960 -2.3 -1.8 Nicotinamide-nucleotide adenylyltransferase, NadM family (EC 2.7.7.1) / ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Ac3H11_2320 -2.3 -8.8 Transcriptional regulator, XRE family compare
Ac3H11_1692 -2.2 -13.5 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 2 (from data) compare
Ac3H11_2067 -2.2 -4.0 Glucokinase (EC 2.7.1.2) compare
Ac3H11_2064 -2.1 -10.1 glucose ABC transporter, permease component 1 (from data) compare
Ac3H11_4054 -2.1 -6.7 General secretion pathway protein F / Type II secretory pathway, component PulF compare
Ac3H11_2492 -2.0 -4.9 FIG004453: protein YceG like compare
Ac3H11_4264 -2.0 -5.8 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
Ac3H11_4474 -2.0 -14.7 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Ac3H11_319 -2.0 -2.3 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
Ac3H11_1695 -2.0 -14.6 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, permease component 1 (from data) compare
Ac3H11_4828 -2.0 -2.9 Ferredoxin compare
Ac3H11_2034 -2.0 -2.5 General secretion pathway protein K compare
Ac3H11_1694 -1.9 -16.1 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, permease component 2 (from data) compare
Ac3H11_2395 -1.9 -3.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Ac3H11_2066 -1.9 -9.2 glucose ABC transporter, ATPase component (from data) compare
Ac3H11_2571 -1.9 -4.2 Outer membrane protein A precursor compare
Ac3H11_4276 -1.9 -10.8 Probable transmembrane protein compare
Ac3H11_1693 -1.9 -13.5 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 1 (from data) compare
Ac3H11_1529 -1.8 -5.6 hypothetical protein compare
Ac3H11_3525 -1.8 -1.4 hypothetical protein compare
Ac3H11_2302 -1.8 -4.2 Acetoacetyl-CoA reductase (EC 1.1.1.36) compare
Ac3H11_2403 -1.8 -6.2 Alkanesulfonate utilization operon LysR-family regulator CbI compare
Ac3H11_518 -1.8 -4.1 Nitrogen regulatory protein P-II compare
Ac3H11_4473 -1.8 -11.3 Twitching motility protein PilT compare
Ac3H11_1453 -1.7 -3.7 Preprotein translocase subunit SecG (TC 3.A.5.1.1) compare
Ac3H11_3837 -1.7 -8.8 Quinolinate synthetase (EC 2.5.1.72) compare
Ac3H11_2065 -1.7 -6.4 glucose ABC transporter, permease component 2 (from data) compare
Ac3H11_4625 -1.7 -6.9 Phenylacetate-coenzyme A ligase (EC 6.2.1.30) compare
Ac3H11_1650 -1.7 -2.0 FIG00537534: hypothetical protein compare
Ac3H11_526 -1.7 -3.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Ac3H11_3838 -1.7 -9.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Ac3H11_3405 -1.7 -3.8 Transcriptional regulator, MarR family compare
Ac3H11_4846 -1.6 -10.8 Transcriptional regulator compare
Ac3H11_781 -1.6 -2.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Ac3H11_132 -1.6 -12.9 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) compare
Ac3H11_2029 -1.6 -4.9 General secretion pathway protein E / Type II secretion cytoplasmic ATP binding protein (PulE, ATPase) compare
Ac3H11_1556 -1.6 -5.8 HpcH/HpaI aldolase compare
Ac3H11_4450 -1.6 -1.9 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Ac3H11_4285 -1.6 -1.4 diguanylate cyclase compare
Ac3H11_2454 -1.6 -4.1 Exodeoxyribonuclease I (EC 3.1.11.1) compare
Ac3H11_2038 -1.6 -2.2 General secretion pathway protein G compare
Ac3H11_2745 -1.5 -2.4 Transcriptional regulator, TetR family compare
Ac3H11_1660 -1.5 -1.6 ATP-dependent DNA helicase UvrD/PcrA compare
Ac3H11_2032 -1.5 -1.5 General secretion pathway protein M compare
Ac3H11_2055 -1.5 -4.7 Probable transcriptional regulator compare
Ac3H11_768 -1.5 -3.6 Chorismate mutase compare
Ac3H11_4431 -1.5 -4.0 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Ac3H11_4241 -1.5 -2.1 hypothetical protein compare
Ac3H11_2030 -1.5 -6.0 General secretion pathway protein D / Type II secretion outermembrane pore forming protein (PulD) compare
Ac3H11_4024 -1.4 -7.1 Sugar kinases, ribokinase family compare
Ac3H11_3154 -1.4 -2.0 hypothetical protein compare
Ac3H11_2062 -1.4 -4.5 glucose ABC transporter, substrate-binding component (from data) compare
Ac3H11_3959 -1.3 -3.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Ac3H11_4094 -1.3 -5.0 Probable two-component transmembrane sensor histidine kinase transcription regulator protein (EC 2.7.3.-) compare
Ac3H11_2035 -1.3 -1.9 General secretion pathway protein J compare
Ac3H11_3241 -1.3 -3.1 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Ac3H11_4237 -1.3 -2.9 hypothetical protein compare
Ac3H11_4709 -1.3 -9.5 Transposase and inactivated derivatives compare
Ac3H11_3402 -1.3 -5.9 Nitrogen regulatory protein P-II compare
Ac3H11_2396 -1.3 -10.2 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, substrate-binding component (from data) compare
Ac3H11_3233 -1.3 -1.5 hypothetical protein compare
Ac3H11_2036 -1.2 -1.2 General secretion pathway protein I compare
Ac3H11_576 -1.2 -2.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Ac3H11_2697 -1.2 -1.3 hypothetical protein compare
Ac3H11_3839 -1.2 -5.4 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Ac3H11_2970 -1.2 -4.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Ac3H11_206 -1.2 -8.2 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Ac3H11_1995 -1.2 -2.1 Tyrosine recombinase XerC compare
Ac3H11_3529 -1.2 -1.0 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Ac3H11_790 -1.1 -4.5 Glycerol-3-phosphate regulon repressor, DeoR family compare
Ac3H11_3925 -1.1 -2.7 FIG00932626: hypothetical protein compare
Ac3H11_3543 -1.1 -2.3 hypothetical protein compare
Ac3H11_2392 -1.1 -6.1 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Ac3H11_3155 -1.1 -4.7 Putative alkanesulfonate metabolism utilization regulator compare
Ac3H11_2063 -1.1 -5.1 Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein) compare
Ac3H11_1044 -1.1 -3.5 tRNA-Leu-TAG compare
Ac3H11_3859 -1.0 -4.0 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Ac3H11_473 -1.0 -4.0 Recombination protein RecR compare
Ac3H11_3884 -1.0 -4.9 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA compare
Ac3H11_2115 -1.0 -3.6 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
Ac3H11_2120 -1.0 -2.4 C-type cytochrome biogenesis protein ResA (thioredoxin) compare
Ac3H11_2326 -1.0 -2.2 Methylisocitrate lyase (EC 4.1.3.30) compare
Ac3H11_955 -1.0 -7.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Ac3H11_3417 -0.9 -1.0 hypothetical protein compare
Ac3H11_1557 -0.9 -6.4 Proposed peptidoglycan lipid II flippase MurJ compare
Ac3H11_4506 -0.9 -3.0 Transcriptional regulator, IclR family compare
Ac3H11_2169 -0.9 -3.4 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Ac3H11_934 -0.9 -5.0 Cell division trigger factor (EC 5.2.1.8) compare
Ac3H11_2060 -0.9 -5.9 two-component system, sensor protein compare
Ac3H11_770 -0.9 -1.8 Lysine exporter protein (LYSE/YGGA) compare
Ac3H11_4845 -0.9 -4.2 Transcriptional regulator, TetR family compare
Ac3H11_2198 -0.9 -1.8 hypothetical protein compare
Ac3H11_2059 -0.9 -4.2 Transaldolase (EC 2.2.1.2) compare
Ac3H11_2042 -0.9 -6.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Ac3H11_3538 -0.9 -1.6 hypothetical protein compare
Ac3H11_1325 -0.9 -0.9 Mg2+ and Co2+ transporters compare
Ac3H11_888 -0.9 -1.3 hypothetical protein compare
Ac3H11_1705 -0.9 -5.0 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) compare
Ac3H11_568 -0.9 -1.5 tRNA-Leu-CAG compare
Ac3H11_3403 -0.9 -5.6 Probable signal peptide protein compare
Ac3H11_930 -0.8 -2.2 hypothetical protein compare
Ac3H11_2419 -0.8 -2.9 Iojap protein compare
Ac3H11_77 -0.8 -1.2 Gsl3115 protein compare
Ac3H11_363 -0.8 -5.6 PhbF compare
Ac3H11_4925 -0.8 -2.7 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Ac3H11_370 -0.8 -1.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Ac3H11_2170 -0.8 -1.2 Methionine ABC transporter ATP-binding protein compare
Ac3H11_1583 -0.8 -1.8 COG1399 protein, clustered with ribosomal protein L32p compare
Ac3H11_2304 -0.8 -7.5 Polyhydroxyalkanoic acid synthase compare
Ac3H11_2713 -0.8 -1.1 Tricarboxylate transport protein TctC compare
Ac3H11_2891 -0.8 -0.9 hypothetical protein compare
Ac3H11_320 -0.8 -2.4 AttE component of AttEFGH ABC transport system compare
Ac3H11_2531 -0.8 -1.3 transcriptional regulator, Crp/Fnr family compare
Ac3H11_3230 -0.8 -2.7 Gluconate utilization system Gnt-I transcriptional repressor compare
Ac3H11_2456 -0.8 -5.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Ac3H11_1006 -0.8 -4.2 Transcriptional regulator, GntR family compare
Ac3H11_3840 -0.8 -2.6 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
Ac3H11_1953 -0.8 -1.4 Transcriptional regulator compare
Ac3H11_4304 -0.8 -1.5 Rhodanese-like domain protein compare
Ac3H11_3824 -0.8 -4.0 L-aspartate oxidase (EC 1.4.3.16) compare
Ac3H11_2101 -0.7 -4.4 Proposed lipoate regulatory protein YbeD compare
Ac3H11_3928 -0.7 -5.0 Putative periplasmic cytochrome type-C oxidoreductase signal peptide protein (EC 1.-.-.-) compare
Ac3H11_3401 -0.7 -4.0 Ammonium transporter compare
Ac3H11_1904 -0.7 -0.8 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) compare
Ac3H11_3886 -0.7 -3.0 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion compare
Ac3H11_373 -0.7 -2.4 Excinuclease ABC subunit C compare
Ac3H11_4956 -0.7 -2.7 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
Ac3H11_4632 -0.7 -3.2 General secretion pathway protein A compare
Ac3H11_412 -0.7 -2.9 3'-to-5' exoribonuclease RNase R compare
Ac3H11_1840 -0.7 -3.7 Ribose operon repressor compare
Ac3H11_3451 -0.7 -1.8 LSU ribosomal protein L25p compare
Ac3H11_2453 -0.7 -1.1 hypothetical protein compare
Ac3H11_2957 -0.7 -4.0 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) compare
Ac3H11_3562 -0.7 -4.4 putative membrane protein compare
Ac3H11_156 -0.7 -3.0 TRAP dicarboxylate transporter, DctQ subunit, unknown substrate 5 compare
Ac3H11_3760 -0.7 -1.5 hypothetical protein compare
Ac3H11_3728 -0.7 -2.6 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Ac3H11_1080 -0.7 -1.1 hypothetical protein compare
Ac3H11_1951 -0.7 -3.6 TRAP-type C4-dicarboxylate transport system, small permease component compare
Ac3H11_774 -0.7 -2.1 Transcriptional regulator, LysR family compare
Ac3H11_3888 -0.7 -4.6 Cytochrome c oxidase polypeptide III (EC 1.9.3.1) compare
Ac3H11_3692 -0.7 -1.3 HupE-UreJ family metal transporter compare
Ac3H11_3425 -0.7 -0.9 hypothetical protein compare
Ac3H11_4795 -0.7 -3.0 putative membrane protein compare
Ac3H11_4056 -0.7 -4.0 Probable calcium-binding signal peptide protein compare
Ac3H11_3583 -0.7 -1.0 hypothetical protein compare
Ac3H11_4864 -0.7 -1.3 hypothetical protein compare
Ac3H11_60 -0.7 -2.8 Tricarboxylate transport protein TctB compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source L-Serine in Acidovorax sp. GW101-3H11

For nitrogen source L-Serine across organisms