Experiment set4IT068 for Pseudomonas fluorescens FW300-N1B4

Compare to:

L-Histidine carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_1590 +1.6 4.4 Histidine utilization repressor compare
Pf1N1B4_5109 +1.3 2.2 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Pf1N1B4_932 +1.2 1.6 FIG00963370: hypothetical protein compare
Pf1N1B4_5763 +1.2 2.6 Nitric oxide reductase activation protein NorQ compare
Pf1N1B4_2925 +1.2 3.2 hypothetical protein compare
Pf1N1B4_4560 +1.2 2.2 Transcriptional regulator, MerR family compare
Pf1N1B4_761 +1.1 2.3 FIG00954879: hypothetical protein compare
Pf1N1B4_2975 +1.1 1.9 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_3134 +1.1 2.1 probable tail fiber assembly-like protein compare
Pf1N1B4_5435 +1.1 2.4 hypothetical protein compare
Pf1N1B4_2739 +1.0 1.4 acetyltransferase, GNAT family compare
Pf1N1B4_5512 +1.0 1.8 hypothetical protein compare
Pf1N1B4_5779 +1.0 2.0 Nitrous oxide reductase maturation protein NosF (ATPase) compare
Pf1N1B4_4700 +1.0 1.5 FIG00956898: hypothetical protein compare
Pf1N1B4_4869 +1.0 2.8 Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16) compare
Pf1N1B4_1612 +1.0 1.7 FIG00955429: hypothetical protein compare
Pf1N1B4_5870 +1.0 1.9 VgrG protein compare
Pf1N1B4_5370 +1.0 1.8 hypothetical protein compare
Pf1N1B4_4582 +1.0 1.7 hypothetical protein compare
Pf1N1B4_5884 +1.0 1.7 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf1N1B4_3191 +1.0 1.6 FIG00953505: hypothetical protein compare
Pf1N1B4_5820 +0.9 2.2 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_4982 +0.9 1.7 Transcriptional regulator, AraC family compare
Pf1N1B4_5447 +0.9 2.0 hypothetical protein compare
Pf1N1B4_4366 +0.9 1.9 hypothetical protein compare
Pf1N1B4_54 +0.9 3.0 Cyclohexadienyl dehydratase (EC 4.2.1.51)(EC 4.2.1.91) compare
Pf1N1B4_4826 +0.9 1.6 glutamine synthetase family protein compare
Pf1N1B4_5801 +0.9 2.3 hypothetical protein compare
Pf1N1B4_68 +0.9 2.0 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_3785 +0.9 1.5 FOG: Ankyrin repeat compare
Pf1N1B4_5726 +0.8 2.4 Ferredoxin compare
Pf1N1B4_4590 +0.8 2.1 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) compare
Pf1N1B4_5919 +0.8 2.8 Signal transduction response regulator / Tetratricopeptide repeat-containing protein compare
Pf1N1B4_4359 +0.8 2.1 PvcA protein, related to known isonitrile synthases compare
Pf1N1B4_650 +0.8 2.4 FIG001943: hypothetical protein YajQ compare
Pf1N1B4_969 +0.8 7.8 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf1N1B4_197 +0.8 1.6 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_4402 +0.8 1.8 SoxH protein, homolog compare
Pf1N1B4_1511 +0.8 1.7 FIG027190: Putative transmembrane protein compare
Pf1N1B4_4433 +0.8 1.8 FIG035246: DoxX family protein compare
Pf1N1B4_4393 +0.8 1.4 Ferredoxin reductase compare
Pf1N1B4_5833 +0.8 1.5 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) compare
Pf1N1B4_4100 +0.8 1.7 probable transmembrane protein compare
Pf1N1B4_5803 +0.8 2.6 Catechol 1,2-dioxygenase (EC 1.13.11.1) compare
Pf1N1B4_407 +0.8 1.1 ADP-ribosylglycohydrolase YegU (EC 3.2.-.-) compare
Pf1N1B4_3413 +0.8 1.4 Transcriptional regulator, LysR family compare
Pf1N1B4_5831 +0.8 2.7 SAM-dependent methyltransferases compare
Pf1N1B4_1886 +0.8 3.2 FIG00956005: hypothetical protein compare
Pf1N1B4_5851 +0.8 1.9 Transcriptional regulator, RpiR family compare
Pf1N1B4_291 +0.8 3.6 Major outer membrane lipoprotein I compare
Pf1N1B4_5920 +0.8 1.7 Transcriptional regulator, AraC family compare
Pf1N1B4_4532 +0.8 1.6 ClpB protein compare
Pf1N1B4_106 +0.8 2.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2442 +0.8 1.9 Electron transfer flavoprotein, beta subunit compare
Pf1N1B4_3485 +0.8 1.4 hypothetical protein compare
Pf1N1B4_4937 +0.8 2.4 Two-component hybrid sensor and regulator compare
Pf1N1B4_675 +0.8 1.7 hypothetical protein compare
Pf1N1B4_3507 +0.7 5.8 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf1N1B4_5527 +0.7 2.4 hypothetical protein compare
Pf1N1B4_3538 +0.7 1.4 Transcriptional regulator, AraC family compare
Pf1N1B4_1756 +0.7 2.0 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases compare
Pf1N1B4_973 +0.7 6.6 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf1N1B4_2177 +0.7 1.0 FIG00953342: hypothetical protein compare
Pf1N1B4_4648 +0.7 1.4 transcriptional regulator, MerR family compare
Pf1N1B4_2114 +0.7 4.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf1N1B4_1115 +0.7 5.0 Dna binding response regulator PrrA (RegA) compare
Pf1N1B4_2736 +0.7 1.5 ATP-dependent RNA helicase PA3950 compare
Pf1N1B4_1704 +0.7 2.3 hypothetical protein compare
Pf1N1B4_4023 +0.7 2.2 hypothetical protein compare
Pf1N1B4_739 +0.7 2.4 Endonuclease III (EC 4.2.99.18) compare
Pf1N1B4_3843 +0.7 2.3 Ribosome modulation factor compare
Pf1N1B4_2637 +0.7 3.5 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
Pf1N1B4_3229 +0.7 4.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_5149 +0.7 2.4 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf1N1B4_4076 +0.7 1.5 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf1N1B4_2244 +0.7 1.6 Taurine-binding periplasmic protein TauA compare
Pf1N1B4_4474 +0.7 1.4 transcription regulator protein compare
Pf1N1B4_6040 +0.7 2.4 FIG00956858: hypothetical protein compare
Pf1N1B4_5853 +0.7 1.6 Glutamine synthetase (EC 6.3.1.2), putative compare
Pf1N1B4_4343 +0.7 1.3 hypothetical protein compare
Pf1N1B4_3050 +0.7 2.4 FIG00958830: hypothetical protein compare
Pf1N1B4_3587 +0.7 1.9 N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) compare
Pf1N1B4_5871 +0.7 1.5 FIG00963848: hypothetical protein compare
Pf1N1B4_5105 +0.7 1.4 Peptide ABC transporter, ATP-binding protein compare
Pf1N1B4_1017 +0.7 2.7 FIG00957554: hypothetical protein compare
Pf1N1B4_5975 +0.7 2.3 2-methylaconitate racemase compare
Pf1N1B4_695 +0.7 1.4 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf1N1B4_5051 +0.7 1.5 Sensor protein DegS compare
Pf1N1B4_4929 +0.7 1.3 Opine oxidase subunit B compare
Pf1N1B4_101 +0.7 1.2 hypothetical protein compare
Pf1N1B4_971 +0.7 5.5 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf1N1B4_3547 +0.6 1.2 DNA-binding response regulator compare
Pf1N1B4_5607 +0.6 1.6 C4-dicarboxylate transport protein compare
Pf1N1B4_3275 +0.6 2.1 L-lysine permease compare
Pf1N1B4_31 +0.6 1.7 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf1N1B4_4448 +0.6 1.4 COGs COG2343 compare
Pf1N1B4_3764 +0.6 1.4 Allantoicase (EC 3.5.3.4) compare
Pf1N1B4_972 +0.6 5.8 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf1N1B4_5374 +0.6 2.6 hypothetical protein compare
Pf1N1B4_3625 +0.6 1.6 Flagellar synthesis regulator FleN compare
Pf1N1B4_5576 +0.6 1.3 hypothetical protein compare
Pf1N1B4_1765 +0.6 2.2 hypothetical protein compare
Pf1N1B4_4280 +0.6 1.7 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf1N1B4_1630 +0.6 2.3 A/G-specific adenine glycosylase (EC 3.2.2.-) compare
Pf1N1B4_4331 +0.6 1.2 Transporter, LysE family compare
Pf1N1B4_4295 +0.6 1.3 FIG00954434: hypothetical protein compare
Pf1N1B4_1180 +0.6 1.1 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_41 +0.6 1.8 hypothetical protein compare
Pf1N1B4_4108 +0.6 1.2 Hydrolase, alpha/beta fold family compare
Pf1N1B4_4715 +0.6 1.1 Transcriptional regulator compare
Pf1N1B4_5087 +0.6 1.9 Glycosyl transferase, group 1 family protein compare
Pf1N1B4_2726 +0.6 1.9 Cobalt-zinc-cadmium resistance protein compare
Pf1N1B4_1094 +0.6 1.4 FIG005080: Possible exported protein compare
Pf1N1B4_3783 +0.6 1.8 FIG00958237: hypothetical protein compare
Pf1N1B4_5844 +0.6 2.1 Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein compare
Pf1N1B4_4727 +0.6 1.5 HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) compare
Pf1N1B4_2366 +0.6 1.8 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf1N1B4_292 +0.6 5.7 ErfK/YbiS/YcfS/YnhG family protein compare
Pf1N1B4_3222 +0.6 1.0 Ferredoxin compare
Pf1N1B4_4755 +0.6 1.1 ribosomal protein S6 glutaminyl transferase related protein compare
Pf1N1B4_3526 +0.6 1.7 Glutathione S-transferase (EC 2.5.1.18) compare
Pf1N1B4_2314 +0.6 1.3 FIG028932: hypothetical protein compare
Pf1N1B4_3115 +0.6 3.5 RNA polymerase sigma factor RpoS compare
Pf1N1B4_4175 +0.6 1.6 Universal stress protein family 5 compare
Pf1N1B4_4604 +0.6 1.3 FMN reductase, NADPH-dependent compare
Pf1N1B4_1901 +0.6 1.9 Putative NADH-flavin reductase compare
Pf1N1B4_5680 +0.6 1.7 DNA polymerase-like protein PA0670 compare
Pf1N1B4_1419 +0.6 2.3 putative membrane protein compare
Pf1N1B4_3787 +0.6 1.6 FIG00960829: hypothetical protein compare
Pf1N1B4_3390 +0.6 1.5 RNA polymerase sigma factor RpoE compare
Pf1N1B4_3232 +0.6 2.0 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6); Glutaconate CoA-transferase subunit A (EC 2.8.3.12) compare
Pf1N1B4_3467 +0.6 1.2 Flagellar biosynthesis protein FlgN compare
Pf1N1B4_5461 +0.6 1.8 hypothetical protein compare
Pf1N1B4_4787 +0.6 1.7 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Pf1N1B4_5889 +0.6 2.1 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf1N1B4_1629 +0.6 2.1 FIG00958480: hypothetical protein compare
Pf1N1B4_1519 +0.6 1.7 3-oxoacyl-[ACP] reductase (EC 1.1.1.100) compare
Pf1N1B4_4341 +0.6 1.7 hypothetical protein compare
Pf1N1B4_5780 +0.6 1.8 Nitrous oxide reductase maturation protein NosD compare
Pf1N1B4_538 +0.6 1.2 hypothetical protein compare
Pf1N1B4_3836 +0.6 1.3 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_4602 +0.6 1.1 Transcriptional regulators, LysR family compare
Pf1N1B4_3892 +0.6 2.2 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps compare
Pf1N1B4_3613 +0.6 1.0 hypothetical protein compare
Pf1N1B4_4063 +0.6 1.6 CrcB protein compare
Pf1N1B4_3959 +0.6 1.7 2-aminoethylphosphonate:pyruvate aminotransferase (EC 2.6.1.37) compare
Pf1N1B4_259 +0.6 1.4 Glutathione peroxidase family protein compare
Pf1N1B4_5736 +0.6 1.5 Nitrate/nitrite transporter compare
Pf1N1B4_4797 +0.6 1.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf1N1B4_3325 +0.6 0.9 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_903 +0.5 2.6 Ribosomal RNA large subunit methyltransferase F (EC 2.1.1.51) compare
Pf1N1B4_2484 +0.5 1.5 hypothetical protein compare
Pf1N1B4_4880 +0.5 1.4 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family compare
Pf1N1B4_3069 +0.5 1.5 FIG00954614: hypothetical protein compare
Pf1N1B4_4455 +0.5 1.1 FIG00953528: hypothetical protein compare
Pf1N1B4_138 +0.5 1.0 Putative dipeptidase, pyoverdin biosynthesis PvdM compare
Pf1N1B4_5018 +0.5 1.1 FIG00962345: hypothetical protein compare
Pf1N1B4_1005 +0.5 1.5 probable membrane protein YPO0899 compare
Pf1N1B4_2791 +0.5 0.8 Putative inner membrane protein (Fragment) compare
Pf1N1B4_1465 +0.5 4.6 Carbamoyltransferase in large core OS assembly cluster compare
Pf1N1B4_1785 +0.5 1.5 Uricase (urate oxidase) (EC 1.7.3.3) compare
Pf1N1B4_4429 +0.5 0.8 No significant database matches compare
Pf1N1B4_4776 +0.5 1.5 Nicotinamidase (EC 3.5.1.19) compare
Pf1N1B4_2851 +0.5 1.1 hypothetical protein compare
Pf1N1B4_3627 +0.5 0.9 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_4928 +0.5 2.1 Ferredoxin reductase compare
Pf1N1B4_5863 +0.5 1.2 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf1N1B4_4419 +0.5 1.0 Organosulfonate utilization protein SsuF compare
Pf1N1B4_1845 +0.5 1.1 FIG00954395: hypothetical protein compare
Pf1N1B4_3572 +0.5 1.9 Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) compare
Pf1N1B4_4336 +0.5 1.1 FMN-dependent NADH-azoreductase compare
Pf1N1B4_1441 +0.5 4.0 Putative esterase, FIGfam005057 compare
Pf1N1B4_3920 +0.5 1.4 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
Pf1N1B4_1042 +0.5 1.4 Dihydroneopterin triphosphate epimerase compare
Pf1N1B4_4603 +0.5 0.8 hypothetical protein compare
Pf1N1B4_3621 +0.5 2.2 Flagellar biosynthesis protein FlhB compare
Pf1N1B4_4098 +0.5 2.6 Putative nucleoside transporter yegT compare
Pf1N1B4_272 +0.5 1.6 Transcriptional regulator, LysR family compare
Pf1N1B4_3794 +0.5 1.3 hypothetical protein compare
Pf1N1B4_4104 +0.5 1.1 Probable transmembrane protein compare
Pf1N1B4_69 +0.5 0.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3954 +0.5 2.1 Hydrolase, carbon-nitrogen family compare
Pf1N1B4_3605 +0.5 0.9 Flagellar motor switch protein FliG compare
Pf1N1B4_3911 +0.5 1.6 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_98 +0.5 2.6 Nucleoside-specific channel-forming protein Tsx precursor compare
Pf1N1B4_1446 +0.5 1.5 Predicted hydroxymethylpyrimidine transporter CytX compare
Pf1N1B4_4133 +0.5 1.5 Mobile element protein compare
Pf1N1B4_3813 +0.5 1.7 Homoserine kinase (EC 2.7.1.39) compare
Pf1N1B4_731 +0.5 1.3 Scaffold protein for [4Fe-4S] cluster assembly ApbC, MRP-like compare
Pf1N1B4_4768 +0.5 1.8 hypothetical protein compare
Pf1N1B4_1263 +0.5 1.3 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_5886 +0.5 1.3 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_1680 +0.5 2.6 Probable membrane-fusion protein compare
Pf1N1B4_3273 +0.5 1.0 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_5022 +0.5 1.3 hypothetical protein compare
Pf1N1B4_970 +0.5 3.6 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf1N1B4_1466 +0.5 2.2 hypothetical protein compare
Pf1N1B4_2835 +0.5 1.5 hypothetical protein compare
Pf1N1B4_3795 +0.5 0.9 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_5880 +0.5 1.0 AttH component of AttEFGH ABC transport system compare


Specific Phenotypes

For 11 genes in this experiment

For carbon source L-Histidine in Pseudomonas fluorescens FW300-N1B4

For carbon source L-Histidine across organisms