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Experiment set4IT062 for
Methanococcus maripaludis S2
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Formate McCas deepwell complete
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS07005
-4.9
-1.7
4Fe-4S binding protein
compare
MMP
_RS06700
-3.8
-16.9
hypothetical protein
compare
MMP
_RS06680
-3.7
-16.3
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06685
-3.6
-16.2
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06345
-3.6
-15.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS00695
-3.3
-2.2
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS02280
-3.3
-2.3
DUF211 domain-containing protein
compare
MMP
_RS05515
-3.1
-11.0
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06355
-3.0
-5.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS08720
-3.0
-3.1
4Fe-4S binding protein
compare
MMP
_RS06715
-3.0
-18.6
cache domain-containing protein
compare
MMP
_RS07635
-3.0
-11.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS03015
-2.9
-17.4
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06720
-2.9
-12.1
response regulator transcription factor
compare
MMP
_RS08460
-2.9
-3.5
proteasome-activating nucleotidase
compare
MMP
_RS06350
-2.9
-10.1
HesA/MoeB/ThiF family protein
compare
MMP
_RS01755
-2.8
-2.5
DUF2097 domain-containing protein
compare
MMP
_RS06730
-2.8
-5.0
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01005
-2.8
-3.4
riboflavin synthase
compare
MMP
_RS06705
-2.7
-11.0
formate/nitrite transporter family protein
compare
MMP
_RS01175
-2.7
-4.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS02900
-2.6
-1.8
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS00300
-2.5
-1.7
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS07380
-2.5
-3.4
transcription elongation factor Spt5
compare
MMP
_RS01020
-2.5
-2.5
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS08715
-2.4
-2.3
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS07445
-2.4
-8.6
helix-turn-helix domain-containing protein
compare
MMP
_RS04605
-2.4
-7.9
cobalt ECF transporter T component CbiQ
compare
MMP
_RS04615
-2.4
-6.7
PDGLE domain-containing protein
compare
MMP
_RS02195
-2.3
-7.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS05920
-2.3
-1.5
50S ribosomal protein L37e
compare
MMP
_RS00305
-2.3
-3.8
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS04890
-2.3
-2.1
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS08745
-2.3
-10.1
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS04585
-2.2
-12.2
AIR synthase related protein
compare
MMP
_RS08820
-2.2
-7.5
hypothetical protein
compare
MMP
_RS00895
-2.2
-8.0
hypothetical protein
compare
MMP
_RS04780
-2.1
-4.0
ribonuclease P
compare
MMP
_RS02135
-2.1
-5.7
DUF5612 domain-containing protein
compare
MMP
_RS06625
-2.1
-3.0
DNA primase
compare
MMP
_RS01225
-2.1
-9.6
DUF5379 domain-containing protein
compare
MMP
_RS06630
-2.0
-2.7
UPF0058 family protein
compare
MMP
_RS06285
-2.0
-3.7
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS04685
-2.0
-5.0
DUF126 domain-containing protein
compare
MMP
_RS00685
-1.9
-5.5
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS01500
-1.9
-4.2
CBS domain-containing protein
compare
MMP
_RS06370
-1.9
-8.0
biotin synthase BioB
compare
MMP
_RS07545
-1.9
-2.5
HTH domain-containing protein
compare
MMP
_RS03640
-1.9
-7.3
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS06895
-1.9
-2.9
selenocysteine-specific translation elongation factor
compare
MMP
_RS07845
-1.8
-6.5
LL-diaminopimelate aminotransferase
compare
MMP
_RS08645
-1.8
-9.6
UPF0179 family protein
compare
MMP
_RS08635
-1.8
-4.1
UbiA family prenyltransferase
compare
MMP
_RS03205
-1.8
-3.0
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS01325
-1.8
-4.9
dihydroneopterin aldolase family protein
compare
MMP
_RS06270
-1.7
-6.6
TIGR00300 family protein
compare
MMP
_RS06400
-1.7
-3.6
4Fe-4S binding protein
compare
MMP
_RS03600
-1.7
-3.4
triose-phosphate isomerase
compare
MMP
_RS06475
-1.7
-6.4
FAD-dependent oxidoreductase
compare
MMP
_RS08210
-1.7
-3.0
phosphatidylglycerophosphatase A
compare
MMP
_RS08650
-1.7
-5.8
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS03315
-1.7
-2.2
ferrous iron transport protein A
compare
MMP
_RS03035
-1.7
-5.3
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS01220
-1.7
-8.9
hypothetical protein
compare
MMP
_RS04500
-1.7
-12.4
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS08790
-1.7
-3.6
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS01610
-1.7
-4.4
hypothetical protein
compare
MMP
_RS08095
-1.7
-9.1
dethiobiotin synthase
compare
MMP
_RS01700
-1.7
-2.1
dihydroxy-acid dehydratase
compare
MMP
_RS03025
-1.7
-6.0
molybdenum cofactor guanylyltransferase
compare
MMP
_RS07735
-1.6
-2.0
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS06340
-1.6
-10.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS02240
-1.6
-4.1
methanogenesis marker 7 protein
compare
MMP
_RS03400
-1.6
-5.3
archease
compare
MMP
_RS06295
-1.6
-7.5
methanogenesis marker 14 protein
compare
MMP
_RS06230
-1.6
-4.3
helix-turn-helix domain-containing protein
compare
MMP
_RS06925
-1.6
-4.9
ribonuclease VapC4
compare
MMP
_RS02010
-1.6
-8.2
PHP domain-containing protein
compare
MMP
_RS02800
-1.6
-5.9
nucleotidyltransferase domain-containing protein
compare
MMP
_RS00515
-1.6
-2.0
DUF655 domain-containing protein
compare
MMP
_RS07575
-1.6
-5.7
RNA ligase partner protein
compare
MMP
_RS01265
-1.6
-6.4
hypothetical protein
compare
MMP
_RS01985
-1.5
-7.2
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS04620
-1.5
-9.4
cobalt transporter CbiM
compare
MMP
_RS02235
-1.5
-10.4
CBS domain-containing protein
compare
MMP
_RS05430
-1.5
-4.5
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS07525
-1.4
-7.9
4Fe-4S binding protein
compare
MMP
_RS00295
-1.4
-4.4
gamma carbonic anhydrase family protein
compare
MMP
_RS00110
-1.4
-4.4
hypothetical protein
compare
MMP
_RS02875
-1.4
-9.5
chorismate pyruvate-lyase family protein
compare
MMP
_RS08100
-1.4
-8.7
8-amino-7-oxononanoate synthase
compare
MMP
_RS05875
-1.4
-4.8
hydroxyethylthiazole kinase
compare
MMP
_RS01365
-1.4
-3.0
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS01385
-1.4
-1.2
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS03435
-1.3
-2.9
ketol-acid reductoisomerase
compare
MMP
_RS08105
-1.3
-9.7
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS07645
-1.3
-6.2
aldehyde dehydrogenase family protein
compare
MMP
_RS00115
-1.3
-10.5
radical SAM protein
compare
MMP
_RS07685
-1.3
-8.9
TIGR01212 family radical SAM protein
compare
MMP
_RS07600
-1.3
-3.6
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06930
-1.3
-7.3
MBL fold metallo-hydrolase
compare
MMP
_RS01980
-1.3
-9.7
trimeric intracellular cation channel family protein
compare
MMP
_RS02355
-1.3
-3.9
30S ribosomal protein S27ae
compare
MMP
_RS03580
-1.3
-3.2
signal recognition particle-docking protein FtsY
compare
MMP
_RS06975
-1.3
-3.2
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS01380
-1.2
-5.2
PHP domain-containing protein
compare
MMP
_RS08435
-1.2
-2.1
Era-like GTP-binding protein
compare
MMP
_RS06885
-1.2
-3.3
50S ribosome-binding GTPase
compare
MMP
_RS04775
-1.2
-4.4
adenosylhomocysteinase
compare
MMP
_RS02190
-1.2
-4.0
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS02345
-1.2
-3.6
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS06105
-1.2
-8.1
hydrogenase maturation peptidase HycI
compare
MMP
_RS07605
-1.2
-4.7
diadenylate cyclase
compare
MMP
_RS07195
-1.2
-8.5
M20 family metallo-hydrolase
compare
MMP
_RS05845
-1.2
-1.9
tRNA-intron lyase
compare
MMP
_RS05545
-1.2
-5.8
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS08300
-1.1
-1.4
metal-sulfur cluster assembly factor
compare
MMP
_RS06020
-1.1
-3.7
archaeoflavoprotein AfpA
compare
MMP
_RS05815
-1.1
-2.3
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS07580
-1.1
-3.5
DUF356 domain-containing protein
compare
MMP
_RS02165
-1.1
-6.7
tRNA-dihydrouridine synthase
compare
MMP
_RS07730
-1.1
-2.3
pyruvate synthase subunit beta
compare
MMP
_RS09020
-1.1
-2.1
hypothetical protein
compare
MMP
_RS05345
-1.1
-4.9
hypothetical protein
compare
MMP
_RS00290
-1.1
-5.3
hypothetical protein
compare
MMP
_RS01725
-1.1
-3.5
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS01720
-1.1
-1.6
replication factor C large subunit
compare
MMP
_RS07555
-1.1
-1.2
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS06315
-1.0
-1.7
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS08445
-1.0
-4.5
DUF2099 family protein
compare
MMP
_RS05540
-1.0
-4.0
hypothetical protein
compare
MMP
_RS05765
-1.0
-7.4
M42 family metallopeptidase
compare
MMP
_RS03250
-1.0
-2.1
MJ1244 family protein
compare
MMP
_RS01545
-1.0
-1.8
CBS domain-containing protein
compare
MMP
_RS06865
-1.0
-2.5
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS02145
-1.0
-4.9
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS00320
-1.0
-2.7
class I SAM-dependent methyltransferase
compare
MMP
_RS00735
-1.0
-5.2
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS06110
-1.0
-2.5
ATP-dependent protease LonB
compare
MMP
_RS00315
-1.0
-3.8
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS08440
-1.0
-2.3
cell division protein SepF
compare
MMP
_RS01830
-0.9
-2.7
tRNA-Val
compare
MMP
_RS05550
-0.9
-0.9
cation:proton antiporter
compare
MMP
_RS07700
-0.9
-6.1
DUF1188 domain-containing protein
compare
MMP
_RS07425
-0.9
-4.6
GTP-binding protein
compare
MMP
_RS03445
-0.9
-1.4
methanogenesis marker 17 protein
compare
MMP
_RS06120
-0.9
-2.8
UPF0147 family protein
compare
MMP
_RS07200
-0.9
-4.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS04870
-0.9
-5.0
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS06215
-0.9
-2.7
30S ribosomal protein S6e
compare
MMP
_RS03110
-0.9
-4.7
glycosyltransferase family 2 protein
compare
MMP
_RS08320
-0.9
-4.5
molybdopterin molybdotransferase MoeA
compare
MMP
_RS05265
-0.9
-2.2
2-isopropylmalate synthase
compare
MMP
_RS07750
-0.9
-3.5
DUF357 domain-containing protein
compare
MMP
_RS07755
-0.9
-1.6
DUF555 domain-containing protein
compare
MMP
_RS06200
-0.9
-6.6
M24 family metallopeptidase
compare
MMP
_RS03095
-0.9
-6.1
diphthine synthase
compare
MMP
_RS06940
-0.8
-2.2
polyprenyl diphosphate synthase
compare
MMP
_RS07695
-0.8
-3.8
DUF3236 domain-containing protein
compare
MMP
_RS00985
-0.8
-4.1
CDC48 family AAA ATPase
compare
MMP
_RS00130
-0.8
-1.7
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS03155
-0.8
-5.2
precorrin-6A reductase
compare
MMP
_RS01840
-0.8
-5.3
TIGR00289 family protein
compare
MMP
_RS08330
-0.8
-4.2
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS01250
-0.8
-3.3
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS00915
-0.8
-5.2
DUF116 domain-containing protein
compare
MMP
_RS04850
-0.8
-7.0
UPF0254 family protein
compare
MMP
_RS07775
-0.8
-5.4
alanine dehydrogenase
compare
MMP
_RS00730
-0.8
-3.3
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS05425
-0.8
-3.3
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS00050
-0.8
-5.0
AarF/UbiB family protein
compare
MMP
_RS00120
-0.8
-4.3
LysR family transcriptional regulator
compare
MMP
_RS01795
-0.8
-1.2
methanogenesis marker 6 protein
compare
MMP
_RS07765
-0.7
-4.9
sodium:alanine symporter family protein
compare
MMP
_RS05510
-0.7
-4.1
Rrf2 family transcriptional regulator
compare
MMP
_RS05925
-0.7
-2.5
small nuclear ribonucleoprotein
compare
MMP
_RS07385
-0.7
-1.3
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS07790
-0.7
-5.0
segregation/condensation protein A
compare
MMP
_RS00725
-0.7
-4.6
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS05245
-0.7
-5.4
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS08725
-0.7
-1.1
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS05250
-0.7
-1.3
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS02130
-0.7
-2.6
zinc metalloprotease HtpX
compare
MMP
_RS00040
-0.7
-3.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS03140
-0.7
-4.9
hypothetical protein
compare
MMP
_RS02245
-0.7
-2.7
hypothetical protein
compare
MMP
_RS02885
-0.7
-5.3
molybdopterin biosynthesis protein
compare
MMP
_RS00810
-0.7
-3.8
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS00720
-0.6
-3.7
metal-dependent hydrolase
compare
MMP
_RS01445
-0.6
-3.4
hypothetical protein
compare
MMP
_RS06980
-0.6
-4.6
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS07630
-0.6
-1.2
ATP-binding cassette domain-containing protein
compare
MMP
_RS07190
-0.6
-3.2
chromosome segregation protein SMC
compare
MMP
_RS08690
-0.6
-4.7
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
compare
MMP
_RS03590
-0.6
-3.8
METTL5 family protein
compare
MMP
_RS01800
-0.6
-2.2
TIGR00303 family protein
compare
MMP
_RS05445
-0.6
-4.0
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS08165
-0.6
-0.6
phosphoglycerate dehydrogenase
compare
MMP
_RS05095
-0.6
-4.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS00475
-0.6
-4.4
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t1 experiments