Experiment set4IT061 for Pseudomonas fluorescens FW300-N1B4

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m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.0 -4.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_2880 -3.6 -11.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1 -3.6 -2.4 Colicin V production protein compare
Pf1N1B4_1307 -3.5 -2.4 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_1408 -3.4 -3.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_3697 -3.3 -9.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_2208 -3.3 -7.2 Polyphosphate kinase (EC 2.7.4.1) compare
Pf1N1B4_4280 -3.3 -2.2 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf1N1B4_2545 -3.3 -11.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1624 -3.3 -7.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_1830 -3.2 -8.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_1534 -3.2 -17.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_5666 -3.1 -3.5 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1831 -3.1 -9.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_4285 -3.0 -4.7 Inositol transport system sugar-binding protein compare
Pf1N1B4_2303 -3.0 -13.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1533 -3.0 -6.6 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_4274 -3.0 -3.9 5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain compare
Pf1N1B4_2384 -2.9 -10.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_2549 -2.9 -8.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_1565 -2.9 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_1627 -2.9 -3.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_15 -2.9 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2548 -2.9 -6.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2284 -2.8 -4.6 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_847 -2.8 -7.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_2488 -2.8 -6.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_2009 -2.7 -4.4 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_742 -2.7 -7.4 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_1626 -2.6 -7.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_3038 -2.6 -6.1 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_2112 -2.6 -13.4 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_2282 -2.6 -8.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3168 -2.6 -4.0 AmpG permease compare
Pf1N1B4_2526 -2.6 -14.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_12 -2.5 -6.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_1067 -2.5 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_5224 -2.5 -3.8 tRNA-Arg-CCT compare
Pf1N1B4_2547 -2.5 -3.6 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_4065 -2.5 -7.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_327 -2.4 -1.6 hypothetical protein compare
Pf1N1B4_1434 -2.4 -6.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2858 -2.4 -9.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_350 -2.4 -7.0 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_2878 -2.4 -7.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_5925 -2.4 -11.0 hypothetical protein compare
Pf1N1B4_4286 -2.4 -5.6 Inositol transport system ATP-binding protein conserved
Pf1N1B4_2338 -2.4 -6.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2489 -2.3 -5.3 Biotin synthesis protein BioH compare
Pf1N1B4_58 -2.3 -6.6 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_2478 -2.3 -8.2 Malate synthase G (EC 2.3.3.9) compare
Pf1N1B4_5665 -2.3 -5.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_4279 -2.3 -6.2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) (from data) conserved
Pf1N1B4_1617 -2.3 -8.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_2272 -2.3 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_2010 -2.3 -6.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_3506 -2.3 -7.0 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_4276 -2.3 -4.9 5-deoxy-glucuronate isomerase (EC 5.3.1.-) compare
Pf1N1B4_4277 -2.3 -3.3 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) compare
Pf1N1B4_3595 -2.3 -2.8 Flagellin protein FlaG compare
Pf1N1B4_2337 -2.3 -4.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2850 -2.3 -6.4 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf1N1B4_1625 -2.3 -6.0 FIG00956267: hypothetical protein compare
Pf1N1B4_2493 -2.2 -2.6 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_4287 -2.2 -4.3 Inositol transport system permease protein compare
Pf1N1B4_1315 -2.2 -8.5 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_1317 -2.2 -3.5 Sensor histidine kinase/response regulator compare
Pf1N1B4_2380 -2.2 -12.5 Cytochrome B561 compare
Pf1N1B4_2859 -2.2 -12.4 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_2377 -2.1 -5.6 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_2879 -2.1 -6.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_5926 -2.1 -11.7 hypothetical protein compare
Pf1N1B4_2487 -2.1 -8.0 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_2011 -2.1 -7.2 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_4275 -2.1 -4.0 Inosose dehydratase (EC 4.2.1.44) compare
Pf1N1B4_762 -2.0 -5.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2491 -2.0 -4.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_2860 -2.0 -6.4 FIG00954153: hypothetical protein compare
Pf1N1B4_4299 -2.0 -4.0 sensor histidine kinase compare
Pf1N1B4_2225 -2.0 -9.9 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_2490 -1.9 -5.9 Biotin synthesis protein BioC compare
Pf1N1B4_4028 -1.9 -3.4 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_5619 -1.9 -3.5 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_2381 -1.9 -10.3 Protein yceI precursor compare
Pf1N1B4_3081 -1.8 -15.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_578 -1.8 -3.8 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_2280 -1.8 -7.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_3468 -1.8 -2.3 Negative regulator of flagellin synthesis FlgM compare
Pf1N1B4_4156 -1.7 -2.9 putative secreted protein compare
Pf1N1B4_3518 -1.7 -2.4 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_3833 -1.7 -6.8 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_5927 -1.7 -13.4 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_27 -1.7 -4.2 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_4038 -1.7 -2.6 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_3692 -1.6 -3.1 Chaperone protein HtpG compare
Pf1N1B4_3720 -1.6 -6.9 Long-chain fatty acid transport protein compare
Pf1N1B4_3812 -1.6 -7.5 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_1614 -1.6 -2.3 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_1827 -1.6 -4.0 FIG00953482: hypothetical protein compare
Pf1N1B4_2857 -1.6 -3.1 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_2851 -1.5 -2.1 hypothetical protein compare
Pf1N1B4_257 -1.5 -5.5 sensor histidine kinase/response regulator compare
Pf1N1B4_1566 -1.5 -6.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_3751 -1.5 -1.7 FIG00953060: hypothetical protein compare
Pf1N1B4_2884 -1.4 -4.2 Paraquat-inducible protein A compare
Pf1N1B4_2885 -1.4 -5.0 Paraquat-inducible protein A compare
Pf1N1B4_3501 -1.4 -4.9 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_5924 -1.3 -7.1 hypothetical protein compare
Pf1N1B4_652 -1.3 -7.5 Sensory box histidine kinase compare
Pf1N1B4_1975 -1.3 -2.0 Transcriptional regulator, AsnC family compare
Pf1N1B4_4833 -1.3 -2.6 DNA-binding response regulator, LuxR family compare
Pf1N1B4_4368 -1.3 -3.5 Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_2189 -1.3 -3.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_835 -1.3 -2.5 Trehalose-6-phosphate hydrolase (EC 3.2.1.93) compare
Pf1N1B4_5817 -1.3 -1.5 Decarboxylase family protein compare
Pf1N1B4_3356 -1.3 -2.1 Cyclic nucleotide-binding protein compare
Pf1N1B4_4957 -1.3 -1.7 Transcriptional regulator, TetR family compare
Pf1N1B4_2169 -1.3 -2.1 FIG00953808: hypothetical protein compare
Pf1N1B4_1113 -1.3 -4.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3906 -1.2 -2.8 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_1906 -1.2 -3.2 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_2485 -1.2 -2.2 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy compare
Pf1N1B4_2486 -1.2 -1.7 hypothetical protein compare
Pf1N1B4_384 -1.2 -1.6 proteinase inhibitor compare
Pf1N1B4_4040 -1.2 -2.4 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
Pf1N1B4_2706 -1.2 -2.3 FIG00954871: hypothetical protein compare
Pf1N1B4_4897 -1.1 -2.2 Transcriptional regulator, LysR family compare
Pf1N1B4_1057 -1.1 -2.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_3368 -1.1 -1.9 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_399 -1.1 -2.1 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) compare
Pf1N1B4_2823 -1.1 -1.8 COG1496: Uncharacterized conserved protein compare
Pf1N1B4_1234 -1.1 -3.4 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_81 -1.1 -2.2 Putative sulfate permease compare
Pf1N1B4_4039 -1.1 -4.3 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
Pf1N1B4_544 -1.1 -2.5 Small-conductance mechanosensitive channel compare
Pf1N1B4_3445 -1.1 -2.6 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_275 -1.1 -1.5 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_349 -1.1 -3.4 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf1N1B4_5699 -1.1 -1.7 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_3725 -1.1 -3.9 Sensory box histidine kinase/response regulator compare
Pf1N1B4_32 -1.1 -2.3 Transcriptional regulator, TetR family compare
Pf1N1B4_4102 -1.1 -2.7 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
Pf1N1B4_2877 -1.1 -5.2 Glycosyltransferase compare
Pf1N1B4_5652 -1.0 -2.5 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf1N1B4_4734 -1.0 -2.5 Fap protein with C39 domain compare
Pf1N1B4_5976 -1.0 -2.1 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) compare
Pf1N1B4_4320 -1.0 -2.5 Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) compare
Pf1N1B4_716 -1.0 -2.4 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_3011 -1.0 -1.9 Tyrosine recombinase XerD compare
Pf1N1B4_1135 -1.0 -2.3 FIG00960055: hypothetical protein compare
Pf1N1B4_1339 -1.0 -2.6 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
Pf1N1B4_2886 -1.0 -6.6 Paraquat-inducible protein B compare
Pf1N1B4_3484 -1.0 -3.6 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf1N1B4_430 -1.0 -2.0 hypothetical protein compare
Pf1N1B4_756 -1.0 -1.6 hypothetical protein compare
Pf1N1B4_3726 -1.0 -3.6 Sensory box histidine kinase/response regulator compare
Pf1N1B4_753 -1.0 -2.3 hypothetical protein compare
Pf1N1B4_3264 -1.0 -2.8 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_3524 -1.0 -2.4 FIG00955363: hypothetical protein compare
Pf1N1B4_4041 -1.0 -2.3 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_5688 -1.0 -3.3 hypothetical protein compare
Pf1N1B4_3403 -1.0 -2.5 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_1329 -1.0 -4.2 Cobalamin biosynthesis protein CobG compare
Pf1N1B4_4939 -1.0 -2.3 sodium/hydrogen exchanger family protein compare
Pf1N1B4_4030 -1.0 -2.1 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_4055 -1.0 -4.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf1N1B4_5760 -1.0 -2.0 Nitric-oxide reductase subunit C (EC 1.7.99.7) compare
Pf1N1B4_5498 -1.0 -1.4 hypothetical protein compare
Pf1N1B4_4473 -1.0 -1.3 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_3723 -1.0 -2.1 FIG00957314: hypothetical protein compare
Pf1N1B4_1653 -0.9 -4.3 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_2479 -0.9 -1.9 Glycine cleavage system transcriptional antiactivator GcvR compare
Pf1N1B4_909 -0.9 -2.1 Ketosteroid isomerase-related protein compare
Pf1N1B4_4107 -0.9 -1.9 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_5371 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_231 -0.9 -3.1 Sensor histidine kinase compare
Pf1N1B4_1615 -0.9 -2.8 Glutaredoxin 3 (Grx3) compare
Pf1N1B4_3887 -0.9 -2.3 CAAX amino terminal protease family protein compare
Pf1N1B4_3069 -0.9 -2.0 FIG00954614: hypothetical protein compare
Pf1N1B4_479 -0.9 -2.2 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_886 -0.9 -1.8 FIG137478: Hypothetical protein compare
Pf1N1B4_770 -0.9 -2.2 hypothetical protein compare
Pf1N1B4_78 -0.9 -2.8 FIG00956937: hypothetical protein compare
Pf1N1B4_373 -0.9 -2.2 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC compare
Pf1N1B4_1153 -0.9 -2.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_4860 -0.9 -1.8 Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-) compare
Pf1N1B4_3709 -0.9 -2.4 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf1N1B4_3142 -0.9 -2.7 C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS compare
Pf1N1B4_2959 -0.9 -2.7 FIG067310: hypothetical protein compare
Pf1N1B4_4029 -0.9 -1.5 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
Pf1N1B4_3152 -0.9 -3.6 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_5624 -0.9 -1.9 Lipase precursor (EC 3.1.1.3) compare
Pf1N1B4_4596 -0.9 -1.6 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
Pf1N1B4_1236 -0.9 -3.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_2874 -0.9 -1.9 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_1683 -0.9 -1.3 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_5838 -0.9 -1.8 FIG00956589: hypothetical protein compare
Pf1N1B4_2540 -0.9 -6.3 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf1N1B4_5124 -0.9 -2.9 two component transcriptional regulator, LuxR family compare
Pf1N1B4_2949 -0.9 -0.9 FIG00956396: hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source m-Inositol in Pseudomonas fluorescens FW300-N1B4

For carbon source m-Inositol across organisms