Experiment set4IT053 for Acidovorax sp. GW101-3H11

Compare to:

LB with Doxycycline hyclate 0.000025 mg/ml

200 most important genes:

  gene name fitness t score description  
Ac3H11_3630 -2.8 -4.1 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Ac3H11_2970 -2.6 -6.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Ac3H11_2121 -2.5 -3.6 putative c'cytochrome compare
Ac3H11_3208 -2.2 -2.4 hypothetical protein compare
Ac3H11_2029 -2.1 -3.7 General secretion pathway protein E / Type II secretion cytoplasmic ATP binding protein (PulE, ATPase) compare
Ac3H11_1801 -2.1 -8.2 HflK protein compare
Ac3H11_2034 -1.9 -2.5 General secretion pathway protein K compare
Ac3H11_4054 -1.8 -5.2 General secretion pathway protein F / Type II secretory pathway, component PulF compare
Ac3H11_220 -1.8 -3.0 hypothetical protein compare
Ac3H11_376 -1.7 -1.1 DNA-binding protein HU-beta compare
Ac3H11_2585 -1.7 -2.0 Na(+) H(+) antiporter subunit E compare
Ac3H11_2038 -1.7 -3.1 General secretion pathway protein G compare
Ac3H11_3417 -1.6 -1.0 hypothetical protein compare
Ac3H11_3690 -1.6 -2.1 Urease beta subunit (EC 3.5.1.5) compare
Ac3H11_4449 -1.5 -2.0 RND efflux system, membrane fusion protein CmeA compare
Ac3H11_3341 -1.5 -2.5 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
Ac3H11_2583 -1.5 -1.6 Na(+) H(+) antiporter subunit C compare
Ac3H11_2509 -1.5 -2.9 Response regulator compare
Ac3H11_3529 -1.4 -1.1 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Ac3H11_1802 -1.4 -7.0 HflC protein compare
Ac3H11_3380 -1.3 -1.2 transcriptional regulator, MarR family compare
Ac3H11_1629 -1.3 -1.4 FIG00901576: hypothetical protein compare
Ac3H11_4952 -1.3 -1.7 FIG00932469: hypothetical protein compare
Ac3H11_4447 -1.3 -4.6 RND efflux system, outer membrane lipoprotein CmeC compare
Ac3H11_1409 -1.3 -2.3 Flagellar hook-length control protein FliK compare
Ac3H11_1752 -1.3 -2.6 COG0613, Predicted metal-dependent phosphoesterases (PHP family) compare
Ac3H11_4461 -1.2 -5.6 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) conserved
Ac3H11_2170 -1.2 -1.2 Methionine ABC transporter ATP-binding protein compare
Ac3H11_2326 -1.2 -2.1 Methylisocitrate lyase (EC 4.1.3.30) compare
Ac3H11_937 -1.2 -8.9 ATP-dependent protease La (EC 3.4.21.53) Type I compare
Ac3H11_1283 -1.2 -2.3 Malic enzyme compare
Ac3H11_3550 -1.2 -3.1 Homolog of E. coli HemX protein compare
Ac3H11_934 -1.2 -4.4 Cell division trigger factor (EC 5.2.1.8) compare
Ac3H11_2004 -1.2 -2.6 ATP-dependent protease HslV (EC 3.4.25.-) compare
Ac3H11_3687 -1.2 -1.1 Urease accessory protein UreE compare
Ac3H11_2032 -1.1 -1.1 General secretion pathway protein M compare
Ac3H11_2571 -1.1 -2.2 Outer membrane protein A precursor compare
Ac3H11_3462 -1.1 -2.7 Heat-inducible transcription repressor HrcA compare
Ac3H11_1027 -1.1 -1.1 FIG01198047: hypothetical protein compare
Ac3H11_1834 -1.1 -6.6 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) compare
Ac3H11_5012 -1.1 -1.0 ribonuclease H compare
Ac3H11_4151 -1.1 -3.7 Flagellar synthesis regulator FleN compare
Ac3H11_2586 -1.1 -3.6 Na(+) H(+) antiporter subunit F compare
Ac3H11_4845 -1.0 -5.1 Transcriptional regulator, TetR family compare
Ac3H11_2030 -1.0 -4.4 General secretion pathway protein D / Type II secretion outermembrane pore forming protein (PulD) compare
Ac3H11_548 -1.0 -1.2 hypothetical protein compare
Ac3H11_1453 -1.0 -2.6 Preprotein translocase subunit SecG (TC 3.A.5.1.1) compare
Ac3H11_83 -1.0 -1.6 hypothetical protein compare
Ac3H11_870 -1.0 -2.0 RNA-binding protein compare
Ac3H11_2285 -1.0 -1.6 Transcriptional regulator, AsnC family compare
Ac3H11_370 -1.0 -1.3 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Ac3H11_3590 -1.0 -0.9 Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) compare
Ac3H11_110 -1.0 -1.8 FIG01198471: hypothetical protein compare
Ac3H11_4506 -1.0 -2.5 Transcriptional regulator, IclR family compare
Ac3H11_3060 -0.9 -1.4 hypothetical protein compare
Ac3H11_4711 -0.9 -2.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Ac3H11_3818 -0.9 -1.0 Methionyl-tRNA synthetase (EC 6.1.1.10) compare
Ac3H11_319 -0.9 -1.5 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
Ac3H11_242 -0.9 -1.8 Mobile element protein compare
Ac3H11_827 -0.9 -3.3 Magnesium and cobalt efflux protein CorC compare
Ac3H11_982 -0.9 -3.1 FIG00348939: hypothetical protein compare
Ac3H11_861 -0.9 -4.2 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Ac3H11_473 -0.9 -3.2 Recombination protein RecR compare
Ac3H11_2730 -0.9 -1.8 hypothetical protein compare
Ac3H11_3080 -0.9 -1.4 Flagellar motor protein compare
Ac3H11_3944 -0.9 -1.1 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Ac3H11_2797 -0.9 -1.7 helix-turn-helix domain protein compare
Ac3H11_784 -0.9 -1.8 Hydrogen peroxide-inducible genes activator compare
Ac3H11_1782 -0.9 -2.1 Putative diheme cytochrome c-553 compare
Ac3H11_3240 -0.9 -1.9 Anthranilate phosphoribosyltransferase like (EC 2.4.2.18) compare
Ac3H11_4313 -0.9 -2.3 Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) compare
Ac3H11_3959 -0.9 -2.5 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Ac3H11_3857 -0.9 -1.9 FIG136845: Rhodanese-related sulfurtransferase compare
Ac3H11_4897 -0.9 -2.0 ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17) compare
Ac3H11_4505 -0.9 -4.5 Putative PROLIN-rich signal peptide protein compare
Ac3H11_1275 -0.9 -0.8 hypothetical protein compare
Ac3H11_4024 -0.9 -4.7 Sugar kinases, ribokinase family compare
Ac3H11_4070 -0.9 -1.6 hypothetical protein compare
Ac3H11_4448 -0.9 -2.5 RND efflux system, inner membrane transporter CmeB compare
Ac3H11_2472 -0.9 -1.9 Antitoxin 1 compare
Ac3H11_2440 -0.9 -3.7 FIG00931200: hypothetical protein compare
Ac3H11_2587 -0.8 -2.2 Na(+) H(+) antiporter subunit G compare
Ac3H11_2584 -0.8 -4.7 Na(+) H(+) antiporter subunit D compare
Ac3H11_174 -0.8 -2.2 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Ac3H11_2033 -0.8 -1.5 General secretion pathway protein L compare
Ac3H11_3126 -0.8 -4.4 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Ac3H11_3179 -0.8 -2.2 Chromosome initiation inhibitor compare
Ac3H11_1133 -0.8 -0.7 hypothetical protein compare
Ac3H11_4776 -0.8 -2.5 hypothetical protein compare
Ac3H11_4633 -0.8 -1.8 putative outer membrane autotransporter barrel compare
Ac3H11_2963 -0.8 -2.3 Nicotinamidase (EC 3.5.1.19) compare
Ac3H11_1569 -0.8 -3.8 Translation elongation factor LepA compare
Ac3H11_3792 -0.8 -0.9 hypothetical protein compare
Ac3H11_2593 -0.8 -1.2 Protein crcB homolog compare
Ac3H11_1032 -0.8 -2.2 Truncated hemoglobins compare
Ac3H11_3981 -0.8 -1.2 UPF0301 protein YqgE compare
Ac3H11_3583 -0.8 -1.1 hypothetical protein compare
Ac3H11_2419 -0.8 -2.1 Iojap protein compare
Ac3H11_4784 -0.8 -2.4 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
Ac3H11_1705 -0.8 -3.4 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) compare
Ac3H11_1357 -0.8 -2.3 Uncharacterized glutathione S-transferase-like protein compare
Ac3H11_2582 -0.8 -4.8 Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B compare
Ac3H11_4656 -0.8 -1.4 hypothetical protein compare
Ac3H11_1044 -0.7 -1.9 tRNA-Leu-TAG compare
Ac3H11_544 -0.7 -4.0 Membrane-bound metal-dependent hydrolase compare
Ac3H11_2966 -0.7 -2.7 hypothetical protein compare
Ac3H11_1567 -0.7 -1.2 Probable transmembrane protein compare
Ac3H11_1080 -0.7 -1.0 hypothetical protein compare
Ac3H11_3500 -0.7 -1.0 hypothetical protein compare
Ac3H11_1354 -0.7 -2.0 FIG00454405: hypothetical protein compare
Ac3H11_3354 -0.7 -0.7 Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3) compare
Ac3H11_2888 -0.7 -1.9 Transcriptional regulator, LysR family compare
Ac3H11_4963 -0.7 -1.8 hypothetical protein compare
Ac3H11_1702 -0.7 -2.8 LSU ribosomal protein L33p @ LSU ribosomal protein L33p, zinc-independent compare
Ac3H11_401 -0.7 -0.7 TolA protein compare
Ac3H11_4473 -0.7 -4.9 Twitching motility protein PilT compare
Ac3H11_778 -0.7 -2.7 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Ac3H11_781 -0.7 -0.9 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Ac3H11_952 -0.7 -0.9 Cytochrome c551/c552 compare
Ac3H11_3482 -0.7 -0.7 hypothetical protein compare
Ac3H11_152 -0.7 -0.8 hypothetical protein compare
Ac3H11_437 -0.7 -2.3 Transcription elongation factor GreA compare
Ac3H11_1182 -0.7 -1.3 Hypothetical ABC transport system, periplasmic component compare
Ac3H11_1298 -0.7 -1.8 Transcriptional regulator, TetR family compare
Ac3H11_283 -0.7 -2.6 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Ac3H11_4202 -0.7 -0.7 hypothetical protein compare
Ac3H11_2741 -0.7 -1.8 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) compare
Ac3H11_3254 -0.7 -2.1 hypothetical protein compare
Ac3H11_3246 -0.7 -1.3 hypothetical protein compare
Ac3H11_2160 -0.7 -1.2 sensory box histidine kinase/response regulator compare
Ac3H11_687 -0.7 -3.9 MotA/TolQ/ExbB proton channel family protein compare
Ac3H11_3569 -0.7 -2.0 TRAP dicarboxylate transporter, DctQ subunit, unknown substrate 6 compare
Ac3H11_4878 -0.7 -2.3 hypothetical protein compare
Ac3H11_2693 -0.7 -2.0 S-adenosylhomocysteine hydrolase compare
Ac3H11_1278 -0.7 -1.3 Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) compare
Ac3H11_3021 -0.7 -0.9 2-hydroxychromene-2-carboxylate isomerase compare
Ac3H11_192 -0.7 -1.2 hypothetical protein compare
Ac3H11_1722 -0.7 -2.7 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Ac3H11_2812 -0.6 -1.0 hypothetical protein compare
Ac3H11_4114 -0.6 -2.0 Excinuclease ABC subunit B compare
Ac3H11_688 -0.6 -2.4 Biopolymer transport protein ExbD/TolR compare
Ac3H11_1652 -0.6 -2.2 FIGfam005179 compare
Ac3H11_1029 -0.6 -1.0 Putative cytoplasmic protein compare
Ac3H11_128 -0.6 -1.8 hypothetical protein compare
Ac3H11_3094 -0.6 -5.9 Small Subunit Ribosomal RNA; ssuRNA; SSU rRNA compare
Ac3H11_2035 -0.6 -1.0 General secretion pathway protein J compare
Ac3H11_1962 -0.6 -1.8 hypothetical protein compare
Ac3H11_3543 -0.6 -1.2 hypothetical protein compare
Ac3H11_4352 -0.6 -2.1 Response regulator compare
Ac3H11_2655 -0.6 -1.6 hypothetical protein compare
Ac3H11_2788 -0.6 -0.9 hypothetical protein compare
Ac3H11_2162 -0.6 -3.7 Cell division protein FtsL compare
Ac3H11_4967 -0.6 -2.2 hypothetical protein compare
Ac3H11_1926 -0.6 -2.8 Isohexenylglutaconyl-CoA hydratase compare
Ac3H11_1787 -0.6 -2.9 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) compare
Ac3H11_4033 -0.6 -1.3 FIG00933378: hypothetical protein compare
Ac3H11_1042 -0.6 -2.1 Probable integral membrane protein compare
Ac3H11_3781 -0.6 -0.8 hypothetical protein compare
Ac3H11_77 -0.6 -0.9 Gsl3115 protein compare
Ac3H11_3817 -0.6 -2.1 strictosidine synthase family protein compare
Ac3H11_3756 -0.6 -0.7 hypothetical protein compare
Ac3H11_2608 -0.6 -2.8 Amidophosphoribosyltransferase (EC 2.4.2.14) compare
Ac3H11_3392 -0.6 -2.2 Transcriptional regulator, DeoR family compare
Ac3H11_1842 -0.6 -2.4 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Ac3H11_1289 -0.6 -1.7 putative transmembrane protein compare
Ac3H11_2043 -0.6 -3.7 OsmC/Ohr family protein compare
Ac3H11_4373 -0.6 -0.9 conserved hypothetical protein compare
Ac3H11_766 -0.6 -1.8 hypothetical protein compare
Ac3H11_2115 -0.6 -2.6 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
Ac3H11_81 -0.6 -1.1 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) compare
Ac3H11_3662 -0.6 -1.1 hypothetical protein compare
Ac3H11_4401 -0.6 -2.7 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) compare
Ac3H11_3112 -0.6 -2.3 tRNA pseudouridine synthase C (EC 4.2.1.70) compare
Ac3H11_3087 -0.6 -1.0 P-hydroxylaminobenzoate lyase compare
Ac3H11_1372 -0.6 -1.5 Flagellar basal-body rod protein FlgG compare
Ac3H11_3124 -0.6 -1.9 hypothetical protein compare
Ac3H11_1800 -0.6 -4.0 GTP-binding protein HflX compare
Ac3H11_4795 -0.6 -2.8 putative membrane protein compare
Ac3H11_373 -0.6 -1.7 Excinuclease ABC subunit C compare
Ac3H11_3858 -0.6 -2.8 Glutaredoxin 3 (Grx3) compare
Ac3H11_348 -0.6 -1.9 hypothetical protein compare
Ac3H11_2036 -0.6 -0.7 General secretion pathway protein I compare
Ac3H11_2575 -0.6 -1.9 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) compare
Ac3H11_2900 -0.6 -1.7 alcohol dehydrogenase, zinc containing compare
Ac3H11_2006 -0.6 -0.8 Cell division protein MraZ compare
Ac3H11_1984 -0.6 -1.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Ac3H11_2456 -0.6 -3.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Ac3H11_1346 -0.6 -0.9 Ser-tRNA(Ala) deacylase; Gly-tRNA(Ala) deacylase compare
Ac3H11_3934 -0.6 -3.6 putative exported protein compare
Ac3H11_3859 -0.6 -3.3 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Ac3H11_3004 -0.6 -1.0 UPF0225 protein YchJ compare
Ac3H11_657 -0.6 -1.9 Sensory histidine kinase QseC compare
Ac3H11_4274 -0.6 -1.6 RNA-binding protein compare
Ac3H11_2441 -0.5 -2.9 FIG00933224: hypothetical protein compare
Ac3H11_4800 -0.5 -1.5 Transporter compare
Ac3H11_2224 -0.5 -3.1 Transcriptional regulator, TetR family compare
Ac3H11_3469 -0.5 -0.9 hypothetical protein compare
Ac3H11_2416 -0.5 -2.0 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Ac3H11_3502 -0.5 -0.5 hypothetical protein compare
Ac3H11_232 -0.5 -1.3 Alkyl hydroperoxide reductase protein F (EC 1.6.4.-) compare


Specific Phenotypes

For 3 genes in this experiment

For stress Doxycycline hyclate in Acidovorax sp. GW101-3H11

For stress Doxycycline hyclate across organisms