Experiment set4IT052 for Acidovorax sp. GW101-3H11

Compare to:

LB with D-Cycloserine 0.05 mg/ml

Group: stress
Media: LB + D-Cycloserine (0.05 mg/ml)
Culturing: acidovorax_3H11_ML3a, 24 deep-well microplate; Multitron, Aerobic, at 30 (C), shaken=750 rpm
Growth: about 4.6 generations
By: Mark on 5/19/2015
Media components: 10 g/L Tryptone, 5 g/L Yeast Extract, 5 g/L Sodium Chloride

Specific Phenotypes

For 41 genes in this experiment

For stress D-Cycloserine in Acidovorax sp. GW101-3H11

For stress D-Cycloserine across organisms

SEED Subsystems

Subsystem #Specific
Methionine Biosynthesis 2
Universal GTPases 2
2-phosphoglycolate salvage 1
ABC transporter branched-chain amino acid (TC 3.A.1.4.1) 1
Branched-Chain Amino Acid Biosynthesis 1
Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. 1
Coenzyme B12 biosynthesis 1
DNA repair, bacterial MutL-MutS system 1
Entner-Doudoroff Pathway 1
Folate Biosynthesis 1
Gentisare degradation 1
Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis 1
Glycerolipid and Glycerophospholipid Metabolism in Bacteria 1
Heat shock dnaK gene cluster extended 1
Hfl operon 1
Isobutyryl-CoA to Propionyl-CoA Module 1
Lipoic acid metabolism 1
Methylglyoxal Metabolism 1
NAD and NADP cofactor biosynthesis global 1
NAD regulation 1
NusA-TFII Cluster 1
Polyhydroxybutyrate metabolism 1
Pyrimidine utilization 1
Pyruvate Alanine Serine Interconversions 1
Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate 1
Queuosine-Archaeosine Biosynthesis 1
Respiratory dehydrogenases 1 1
Ribosome biogenesis bacterial 1
Salicylate and gentisate catabolism 1
Toluene degradation 1
Translation initiation factors eukaryotic and archaeal 1
Tryptophan synthesis 1
Valine degradation 1

Metabolic Maps

Color code by fitness: see overview map or list of maps.

Maps containing gene(s) with specific phenotypes:

MetaCyc Pathways

Pathways that contain genes with specific phenotypes:

Pathway #Steps #Present #Specific
L-glutamine degradation I 1 1 1
4-aminobenzoate biosynthesis I 2 2 1
L-glutamate biosynthesis I 2 2 1
β-alanine degradation II 2 2 1
putrescine degradation V 2 1 1
ethylene glycol degradation 2 1 1
β-alanine degradation I 2 1 1
putrescine degradation I 2 1 1
NAD salvage pathway II (PNC IV cycle) 5 4 2
ammonia assimilation cycle III 3 3 1
ethanol degradation IV 3 3 1
gentisate degradation I 3 3 1
ethanol degradation II 3 3 1
ketolysis 3 3 1
NAD de novo biosynthesis I 6 5 2
NAD de novo biosynthesis IV (anaerobic) 6 4 2
NAD de novo biosynthesis III 6 4 2
ethanol degradation III 3 2 1
hypotaurine degradation 3 2 1
putrescine degradation IV 3 2 1
L-methionine salvage from L-homocysteine 3 1 1
resorcinol degradation 3 1 1
4-toluenecarboxylate degradation 3 1 1
histamine degradation 3 1 1
glutathione-peroxide redox reactions 3 1 1
pentachlorophenol degradation 10 4 3
NAD salvage pathway I (PNC VI cycle) 7 5 2
octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) 12 12 3
L-asparagine biosynthesis III (tRNA-dependent) 4 4 1
L-methionine biosynthesis III 4 4 1
reactive oxygen species degradation 4 4 1
gondoate biosynthesis (anaerobic) 4 4 1
phytol degradation 4 3 1
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 4 3 1
glutaminyl-tRNAgln biosynthesis via transamidation 4 3 1
4-sulfocatechol degradation 4 2 1
fatty acid α-oxidation I (plants) 4 2 1
γ-resorcylate degradation I 4 1 1
D-arabinose degradation II 4 1 1
4-aminophenol degradation 4 1 1
4-toluenesulfonate degradation I 4 1 1
4-hydroxy-2-nonenal detoxification 4 1 1
putrescine degradation III 4 1 1
γ-resorcylate degradation II 4 1 1
L-tryptophan degradation X (mammalian, via tryptamine) 4 1 1
palmitate biosynthesis III 29 28 7
tetradecanoate biosynthesis (mitochondria) 25 23 6
palmitate biosynthesis II (type II fatty acid synthase) 31 29 7
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) 9 8 2
oleate biosynthesis IV (anaerobic) 14 13 3
superpathway of fatty acids biosynthesis (E. coli) 53 49 11
fatty acid elongation -- saturated 5 5 1
superpathway of unsaturated fatty acids biosynthesis (E. coli) 20 18 4
8-amino-7-oxononanoate biosynthesis IV 5 4 1
cis-vaccenate biosynthesis 5 4 1
ketogenesis 5 3 1
NAD salvage pathway V (PNC V cycle) 5 3 1
acrylate degradation I 5 3 1
propanoyl-CoA degradation II 5 3 1
L-tyrosine degradation I 5 3 1
L-methionine biosynthesis I 5 3 1
4-chlorocatechol degradation 5 3 1
octane oxidation 5 3 1
sphingosine and sphingosine-1-phosphate metabolism 10 4 2
3-chlorocatechol degradation II (ortho) 5 2 1
mitochondrial NADPH production (yeast) 5 2 1
3-chlorocatechol degradation I (ortho) 5 2 1
dopamine degradation 5 1 1
4-nitrophenol degradation I 5 1 1
4-nitrophenol degradation II 5 1 1
4-hydroxyacetophenone degradation 5 1 1
superpathway of fatty acid biosynthesis II (plant) 43 38 8
8-amino-7-oxononanoate biosynthesis I 11 9 2
even iso-branched-chain fatty acid biosynthesis 34 30 6
anteiso-branched-chain fatty acid biosynthesis 34 30 6
odd iso-branched-chain fatty acid biosynthesis 34 30 6
(5Z)-dodecenoate biosynthesis I 6 6 1
stearate biosynthesis II (bacteria and plants) 6 5 1
(5Z)-dodecenoate biosynthesis II 6 5 1
stearate biosynthesis IV 6 4 1
3-methyl-branched fatty acid α-oxidation 6 3 1
5-nitroanthranilate degradation 6 3 1
petroselinate biosynthesis 6 2 1
alkane oxidation 6 1 1
noradrenaline and adrenaline degradation 13 4 2
streptorubin B biosynthesis 34 20 5
L-glutamate and L-glutamine biosynthesis 7 7 1
superpathway of glycol metabolism and degradation 7 5 1
4,5-dichlorocatechol degradation 7 4 1
2,4,6-trichlorophenol degradation 7 3 1
chlorosalicylate degradation 7 3 1
serotonin degradation 7 3 1
2,4-dinitrotoluene degradation 7 2 1
ceramide degradation by α-oxidation 7 2 1
myo-inositol degradation I 7 1 1
limonene degradation IV (anaerobic) 7 1 1
biotin biosynthesis I 15 13 2
superpathway of fatty acid biosynthesis I (E. coli) 16 15 2
L-citrulline biosynthesis 8 7 1
L-valine degradation I 8 6 1
superpathway of L-homoserine and L-methionine biosynthesis 8 6 1
superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) 8 4 1
3,5-dichlorocatechol degradation 8 4 1
superpathway of ornithine degradation 8 3 1
glutathione-mediated detoxification I 8 3 1
ceramide and sphingolipid recycling and degradation (yeast) 16 4 2
2-allylmalonyl-CoA biosynthesis 8 2 1
aromatic biogenic amine degradation (bacteria) 8 1 1
aspartate superpathway 25 22 3
superpathway of L-methionine biosynthesis (transsulfuration) 9 7 1
superpathway of S-adenosyl-L-methionine biosynthesis 9 7 1
folate transformations III (E. coli) 9 7 1
NAD de novo biosynthesis II (from tryptophan) 9 6 1
3,4,6-trichlorocatechol degradation 9 5 1
1,4-dichlorobenzene degradation 9 4 1
photorespiration I 9 4 1
photorespiration III 9 4 1
Entner-Doudoroff pathway II (non-phosphorylative) 9 4 1
2,4,5-trichlorophenoxyacetate degradation 9 3 1
gliotoxin biosynthesis 9 1 1
chloramphenicol biosynthesis 9 1 1
glutathione-mediated detoxification II 9 1 1
superpathway of tetrahydrofolate biosynthesis 10 9 1
3-phenylpropanoate degradation 10 6 1
peptidoglycan recycling II 10 5 1
photorespiration II 10 4 1
pinoresinol degradation 10 2 1
myo-, chiro- and scyllo-inositol degradation 10 1 1
folate transformations II (plants) 11 8 1
γ-hexachlorocyclohexane degradation 11 6 1
NAD salvage (plants) 11 5 1
superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation 11 4 1
superpathway of candicidin biosynthesis 11 3 1
superpathway of L-methionine biosynthesis (by sulfhydrylation) 12 12 1
superpathway of tetrahydrofolate biosynthesis and salvage 12 11 1
superpathway of L-citrulline metabolism 12 9 1
indole glucosinolate activation (intact plant cell) 12 3 1
camalexin biosynthesis 12 2 1
folate transformations I 13 7 1
superpathway of L-arginine and L-ornithine degradation 13 6 1
superpathway of NAD biosynthesis in eukaryotes 14 9 1
superpathway of L-methionine salvage and degradation 16 7 1
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I 18 16 1
mycolate biosynthesis 205 21 5
superpathway of pentose and pentitol degradation 42 14 1
superpathway of mycolate biosynthesis 239 22 5
superpathway of chorismate metabolism 59 44 1