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Experiment set4IT051 for
Methanococcus maripaludis S2
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Formate McCas deepwell complete
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06680
-8.3
-16.8
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06895
-8.2
-4.4
selenocysteine-specific translation elongation factor
compare
MMP
_RS06685
-8.0
-15.3
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS05515
-7.7
-9.1
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06700
-7.7
-16.0
hypothetical protein
compare
MMP
_RS01175
-7.1
-7.0
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06355
-6.6
-4.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS01020
-6.2
-1.9
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS01325
-6.2
-4.5
dihydroneopterin aldolase family protein
compare
MMP
_RS03015
-6.1
-12.9
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06285
-6.0
-4.4
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06730
-6.0
-4.6
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS06625
-5.9
-4.3
DNA primase
compare
MMP
_RS03315
-5.9
-3.1
ferrous iron transport protein A
compare
MMP
_RS08715
-5.8
-4.4
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS02280
-5.8
-1.8
DUF211 domain-containing protein
compare
MMP
_RS06400
-5.8
-3.8
4Fe-4S binding protein
compare
MMP
_RS06475
-5.7
-8.6
FAD-dependent oxidoreductase
compare
MMP
_RS00305
-5.7
-3.9
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08720
-5.7
-3.4
4Fe-4S binding protein
compare
MMP
_RS07635
-5.6
-12.8
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS06715
-5.4
-23.6
cache domain-containing protein
compare
MMP
_RS01005
-5.4
-2.3
riboflavin synthase
compare
MMP
_RS08790
-5.3
-4.9
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS06345
-5.3
-12.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS02900
-5.1
-1.6
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS06705
-5.0
-12.9
formate/nitrite transporter family protein
compare
MMP
_RS06350
-4.9
-7.7
HesA/MoeB/ThiF family protein
compare
MMP
_RS07005
-4.9
-1.5
4Fe-4S binding protein
compare
MMP
_RS04775
-4.9
-6.6
adenosylhomocysteinase
compare
MMP
_RS06295
-4.8
-9.5
methanogenesis marker 14 protein
compare
MMP
_RS06370
-4.8
-8.5
biotin synthase BioB
compare
MMP
_RS08635
-4.8
-4.3
UbiA family prenyltransferase
compare
MMP
_RS08300
-4.8
-2.5
metal-sulfur cluster assembly factor
compare
MMP
_RS05920
-4.7
-1.5
50S ribosomal protein L37e
compare
MMP
_RS03475
-4.7
-1.5
hypothetical protein
compare
MMP
_RS06720
-4.7
-9.8
response regulator transcription factor
compare
MMP
_RS04605
-4.7
-5.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS08105
-4.7
-11.0
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS08460
-4.7
-4.7
proteasome-activating nucleotidase
compare
MMP
_RS04500
-4.7
-22.1
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS04780
-4.7
-6.3
ribonuclease P
compare
MMP
_RS06630
-4.6
-2.0
UPF0058 family protein
compare
MMP
_RS04585
-4.6
-11.7
AIR synthase related protein
compare
MMP
_RS01500
-4.5
-4.5
CBS domain-containing protein
compare
MMP
_RS08095
-4.5
-11.1
dethiobiotin synthase
compare
MMP
_RS07645
-4.4
-12.2
aldehyde dehydrogenase family protein
compare
MMP
_RS04685
-4.4
-6.0
DUF126 domain-containing protein
compare
MMP
_RS08820
-4.4
-7.5
hypothetical protein
compare
MMP
_RS03035
-4.3
-7.2
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS01800
-4.2
-8.5
TIGR00303 family protein
compare
MMP
_RS01225
-4.2
-6.8
DUF5379 domain-containing protein
compare
MMP
_RS00895
-4.2
-6.2
hypothetical protein
compare
MMP
_RS09020
-4.1
-3.6
hypothetical protein
compare
MMP
_RS08100
-4.0
-11.3
8-amino-7-oxononanoate synthase
compare
MMP
_RS01985
-3.9
-13.4
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS07195
-3.9
-16.0
M20 family metallo-hydrolase
compare
MMP
_RS03435
-3.9
-3.3
ketol-acid reductoisomerase
compare
MMP
_RS06975
-3.8
-5.0
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS02195
-3.8
-5.8
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS07445
-3.8
-6.6
helix-turn-helix domain-containing protein
compare
MMP
_RS04615
-3.8
-8.5
PDGLE domain-containing protein
compare
MMP
_RS07580
-3.7
-4.2
DUF356 domain-containing protein
compare
MMP
_RS01755
-3.7
-2.6
DUF2097 domain-containing protein
compare
MMP
_RS02240
-3.7
-7.5
methanogenesis marker 7 protein
compare
MMP
_RS01385
-3.6
-1.6
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS08645
-3.6
-11.6
UPF0179 family protein
compare
MMP
_RS01795
-3.6
-3.9
methanogenesis marker 6 protein
compare
MMP
_RS07380
-3.6
-3.5
transcription elongation factor Spt5
compare
MMP
_RS06925
-3.6
-5.1
ribonuclease VapC4
compare
MMP
_RS03580
-3.6
-4.7
signal recognition particle-docking protein FtsY
compare
MMP
_RS05845
-3.5
-4.4
tRNA-intron lyase
compare
MMP
_RS03025
-3.5
-6.7
molybdenum cofactor guanylyltransferase
compare
MMP
_RS00685
-3.5
-7.1
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS04620
-3.5
-12.3
cobalt transporter CbiM
compare
MMP
_RS02875
-3.5
-17.0
chorismate pyruvate-lyase family protein
compare
MMP
_RS02345
-3.3
-6.2
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS00515
-3.3
-1.9
DUF655 domain-containing protein
compare
MMP
_RS08435
-3.3
-4.1
Era-like GTP-binding protein
compare
MMP
_RS06340
-3.3
-12.3
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS06315
-3.3
-2.3
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS08745
-3.3
-8.4
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS05345
-3.2
-10.8
hypothetical protein
compare
MMP
_RS03600
-3.2
-3.9
triose-phosphate isomerase
compare
MMP
_RS07630
-3.2
-3.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS03400
-3.2
-3.8
archease
compare
MMP
_RS06270
-3.2
-9.7
TIGR00300 family protein
compare
MMP
_RS01545
-3.1
-2.7
CBS domain-containing protein
compare
MMP
_RS07600
-3.1
-3.2
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06120
-3.1
-3.3
UPF0147 family protein
compare
MMP
_RS01220
-3.1
-11.7
hypothetical protein
compare
MMP
_RS06230
-3.0
-4.6
helix-turn-helix domain-containing protein
compare
MMP
_RS02355
-3.0
-7.5
30S ribosomal protein S27ae
compare
MMP
_RS02135
-3.0
-6.7
DUF5612 domain-containing protein
compare
MMP
_RS05930
-3.0
-5.2
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS07545
-2.9
-2.3
HTH domain-containing protein
compare
MMP
_RS07845
-2.9
-5.3
LL-diaminopimelate aminotransferase
compare
MMP
_RS06020
-2.9
-7.6
archaeoflavoprotein AfpA
compare
MMP
_RS08650
-2.9
-4.4
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS07735
-2.8
-2.1
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS00110
-2.8
-6.0
hypothetical protein
compare
MMP
_RS01265
-2.8
-4.6
hypothetical protein
compare
MMP
_RS05265
-2.7
-4.9
2-isopropylmalate synthase
compare
MMP
_RS03155
-2.7
-11.8
precorrin-6A reductase
compare
MMP
_RS03640
-2.7
-8.1
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS00295
-2.7
-4.6
gamma carbonic anhydrase family protein
compare
MMP
_RS01725
-2.7
-7.0
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS04890
-2.6
-1.7
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS08210
-2.6
-4.9
phosphatidylglycerophosphatase A
compare
MMP
_RS00695
-2.6
-2.2
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS01380
-2.6
-5.6
PHP domain-containing protein
compare
MMP
_RS01700
-2.5
-2.3
dihydroxy-acid dehydratase
compare
MMP
_RS00115
-2.5
-16.3
radical SAM protein
compare
MMP
_RS03445
-2.5
-2.2
methanogenesis marker 17 protein
compare
MMP
_RS05555
-2.4
-3.0
DUF4040 domain-containing protein
compare
MMP
_RS08445
-2.3
-6.3
DUF2099 family protein
compare
MMP
_RS06215
-2.3
-4.9
30S ribosomal protein S6e
compare
MMP
_RS02190
-2.2
-3.6
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS06105
-2.2
-11.2
hydrogenase maturation peptidase HycI
compare
MMP
_RS01830
-2.2
-3.7
tRNA-Val
compare
MMP
_RS01980
-2.2
-17.0
trimeric intracellular cation channel family protein
compare
MMP
_RS07200
-2.2
-7.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS07750
-2.2
-7.8
DUF357 domain-containing protein
compare
MMP
_RS02145
-2.1
-6.1
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05430
-2.1
-4.7
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS07605
-2.1
-2.9
diadenylate cyclase
compare
MMP
_RS02010
-2.1
-10.0
PHP domain-containing protein
compare
MMP
_RS07525
-2.1
-8.8
4Fe-4S binding protein
compare
MMP
_RS03960
-2.1
-1.8
hypothetical protein
compare
MMP
_RS07390
-2.1
-2.0
cell division protein FtsZ
compare
MMP
_RS07575
-2.1
-8.4
RNA ligase partner protein
compare
MMP
_RS01610
-2.0
-3.6
hypothetical protein
compare
MMP
_RS06930
-2.0
-13.3
MBL fold metallo-hydrolase
compare
MMP
_RS06885
-2.0
-4.6
50S ribosome-binding GTPase
compare
MMP
_RS07385
-2.0
-1.8
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS07685
-2.0
-11.0
TIGR01212 family radical SAM protein
compare
MMP
_RS07730
-1.9
-2.3
pyruvate synthase subunit beta
compare
MMP
_RS08440
-1.9
-4.5
cell division protein SepF
compare
MMP
_RS07755
-1.9
-2.3
DUF555 domain-containing protein
compare
MMP
_RS05440
-1.9
-11.6
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS02165
-1.9
-11.4
tRNA-dihydrouridine synthase
compare
MMP
_RS02800
-1.9
-5.5
nucleotidyltransferase domain-containing protein
compare
MMP
_RS05925
-1.8
-4.6
small nuclear ribonucleoprotein
compare
MMP
_RS07555
-1.8
-1.5
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS03095
-1.8
-10.9
diphthine synthase
compare
MMP
_RS00300
-1.8
-1.3
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS02235
-1.8
-9.2
CBS domain-containing protein
compare
MMP
_RS05875
-1.7
-3.2
hydroxyethylthiazole kinase
compare
MMP
_RS00050
-1.7
-7.3
AarF/UbiB family protein
compare
MMP
_RS00985
-1.7
-4.1
CDC48 family AAA ATPase
compare
MMP
_RS04710
-1.7
-1.7
hypothetical protein
compare
MMP
_RS00320
-1.7
-3.7
class I SAM-dependent methyltransferase
compare
MMP
_RS01250
-1.6
-5.0
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS05540
-1.6
-2.6
hypothetical protein
compare
MMP
_RS01365
-1.6
-3.2
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS01840
-1.6
-7.0
TIGR00289 family protein
compare
MMP
_RS06940
-1.5
-3.2
polyprenyl diphosphate synthase
compare
MMP
_RS00900
-1.5
-3.3
50S ribosomal protein L39e
compare
MMP
_RS03140
-1.5
-10.9
hypothetical protein
compare
MMP
_RS06865
-1.5
-1.2
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS00040
-1.5
-6.7
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS02340
-1.5
-2.7
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS00290
-1.5
-7.2
hypothetical protein
compare
MMP
_RS06130
-1.4
-3.8
peptidylprolyl isomerase
compare
MMP
_RS03110
-1.4
-6.0
glycosyltransferase family 2 protein
compare
MMP
_RS07420
-1.4
-3.7
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS04870
-1.4
-4.8
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS07425
-1.4
-5.0
GTP-binding protein
compare
MMP
_RS05815
-1.4
-1.2
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS01475
-1.4
-8.1
phosphosulfolactate synthase
compare
MMP
_RS00750
-1.4
-4.4
fumarate hydratase
compare
MMP
_RS05245
-1.3
-8.9
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS05545
-1.3
-6.6
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS03145
-1.3
-6.9
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS00620
-1.3
-6.8
4Fe-4S binding protein
compare
MMP
_RS01335
-1.3
-4.0
prefoldin subunit beta
compare
MMP
_RS05765
-1.3
-6.1
M42 family metallopeptidase
compare
MMP
_RS07190
-1.3
-6.4
chromosome segregation protein SMC
compare
MMP
_RS03700
-1.3
-5.5
sodium:proton antiporter
compare
MMP
_RS08840
-1.3
-7.6
class I SAM-dependent methyltransferase
compare
MMP
_RS07790
-1.2
-8.2
segregation/condensation protein A
compare
MMP
_RS00725
-1.2
-7.1
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS06200
-1.2
-9.5
M24 family metallopeptidase
compare
MMP
_RS07365
-1.2
-8.2
2-phosphoglycerate kinase
compare
MMP
_RS08690
-1.2
-9.9
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
compare
MMP
_RS05445
-1.2
-6.6
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS06395
-1.2
-4.8
ThiF family adenylyltransferase
compare
MMP
_RS04850
-1.2
-10.0
UPF0254 family protein
compare
MMP
_RS03250
-1.2
-2.1
MJ1244 family protein
compare
MMP
_RS01665
-1.2
-2.2
DUF2111 domain-containing protein
compare
MMP
_RS00120
-1.2
-5.7
LysR family transcriptional regulator
compare
MMP
_RS08330
-1.2
-5.1
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS06110
-1.1
-3.2
ATP-dependent protease LonB
compare
MMP
_RS06980
-1.1
-6.1
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS00475
-1.1
-7.3
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS08570
-1.1
-7.7
coenzyme F420-0:L-glutamate ligase
compare
MMP
_RS07700
-1.1
-6.9
DUF1188 domain-containing protein
compare
MMP
_RS03555
-1.1
-6.9
transcriptional regulator
compare
MMP
_RS00450
-1.1
-3.3
4Fe-4S binding protein
compare
MMP
_RS07695
-1.1
-4.7
DUF3236 domain-containing protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t2 experiments