Experiment set4IT050 for Sinorhizobium meliloti 1021

Compare to:

LB with Polymyxin B sulfate 0.00005 mg/ml

200 most important genes:

  gene name fitness t score description  
SMc02232 -6.4 -2.9 hypothetical protein compare
SMc02641 -6.0 -3.4 UDP-glucose 6-dehydrogenase compare
SMc02144 -5.7 -4.2 phosphate ABC transporter permease compare
SMc01220 -5.7 -3.8 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc02147 -5.4 -7.7 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc01280 -5.3 -1.8 protease compare
SMc04209 -5.1 -11.3 hypothetical protein compare
SMc03100 -5.1 -1.8 hypothetical protein compare
SMc02142 -5.1 -5.7 phosphate transporter ATP-binding protein compare
SMc02909 -5.1 -2.0 transglycosylase transmembrane protein compare
SMc02115 -5.0 -1.0 hypothetical protein compare
SMc02485 -4.9 -1.7 signal peptide protein compare
SMc00067 -4.8 -12.2 outer-membranne lipoprotein compare
SMc02435 -4.7 -2.1 methyltransferase compare
SMc02140 -4.7 -1.3 phosphate regulon transcriptional regulatory protein compare
SMc00369 -4.5 -0.9 oxidoreductase compare
SMc01929 -4.5 -3.1 hypothetical protein compare
SMc02510 -4.4 -0.9 ferric uptake regulation protein compare
SMc01881 -4.4 -2.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc02234 -4.4 -3.1 hypothetical protein compare
SMc01221 -4.3 -12.1 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc00492 -4.3 -0.9 hypothetical protein compare
SMc01360 -4.2 -2.8 aspartate carbamoyltransferase catalytic subunit compare
SMc01347 -4.2 -4.6 hypothetical protein compare
SMc00334 -4.0 -1.4 cytidylate kinase compare
SMc01447 -4.0 -0.8 hypothetical protein compare
SMc00914 -3.9 -4.3 oxidoreductase compare
SMc02149 -3.8 -1.5 hypothetical protein compare
SMc01187 -3.8 -1.8 rare lipoprotein A compare
SMc02114 -3.8 -3.8 hypothetical protein compare
SMc01361 -3.7 -4.0 dihydroorotase compare
SMc03763 -3.6 -4.8 cytosine-specific methyltransferase compare
SMa0753 -3.6 -0.7 hypothetical protein compare
SMc00143 -3.5 -1.2 molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
SMc01147 -3.4 -2.1 coproporphyrinogen III oxidase compare
SMc00987 -3.4 -2.9 hypothetical protein compare
SMc02505 -3.4 -0.9 hypothetical protein compare
SMc04024 -3.4 -6.4 membrane-bound lytic murein transglycosylase compare
SMc00689 -3.3 -4.4 lipoprotein compare
SMc02833 -3.3 -1.9 penicillin-insensitive murein endopeptidase compare
SMc02582 -3.2 -3.1 hypothetical protein compare
SMc04330 -3.2 -2.0 trimethylamine methyltransferase compare
SMc00691 -3.1 -4.0 site-specific tyrosine recombinase XerD compare
SMc01800 -3.1 -0.9 cytochrome C oxidase assembly transmembrane protein compare
SMc03849 -3.1 -1.1 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc03839 -3.1 -1.6 hypothetical protein compare
SMc00191 -3.0 -1.9 hypothetical protein compare
SMc02858 -3.0 -0.6 chaperone protein DnaJ compare
SMc01183 -3.0 -1.4 LexA repressor compare
SMc01845 -2.9 -2.1 transglycosylase transmembrane protein compare
SMc00073 -2.9 -2.1 hypothetical protein compare
SMc00815 -2.9 -1.5 inosine 5'-monophosphate dehydrogenase compare
SMc02778 -2.9 -0.8 hydroxyacid aldolase compare
SMc02867 -2.9 -3.4 multidrug-efflux system transmembrane protein compare
SM_b21580 -2.9 -1.8 hypothetical protein compare
SMa0789 -2.8 -2.8 GntR family transcriptional regulator compare
SMc03242 -2.7 -1.6 GTP-binding protein compare
SMc00963 -2.7 -3.4 hypothetical protein compare
SMc00241 -2.7 -1.7 transcriptional regulator compare
SMc02868 -2.7 -4.6 multidrug efflux system protein compare
SMc02145 -2.6 -0.7 signal peptide protein compare
SMc02640 -2.6 -4.2 UDP-glucuronic acid epimerase compare
SMc02850 -2.6 -3.2 DNA polymerase I compare
SM_b20803 -2.6 -2.3 3-deoxy-manno-octulosonate cytidylyltransferase compare
SMc01208 -2.6 -2.3 peptidyl-prolyl cis-trans isomerase B protein compare
SM_b21417 -2.5 -5.9 CDP-glucose 4,6-dehydratase compare
SMc02683 -2.5 -1.7 hypothetical protein compare
SMc02724 -2.5 -2.3 hypothetical protein compare
SMc02753 -2.5 -1.2 PTS system transporter subunit IIA compare
SMc03978 -2.5 -3.0 transketolase compare
SM_b20563 -2.4 -1.6 hypothetical protein compare
SMc01850 -2.4 -2.7 hypothetical protein compare
SMc03996 -2.4 -5.4 thiamine-phosphate pyrophosphorylase compare
SMc01438 -2.4 -4.1 protease precursor signal peptide protein compare
SMc02484 -2.3 -1.9 amino acid efflux transmembrane protein compare
SMa0211 -2.3 -0.6 hypothetical protein compare
SMc01853 -2.3 -4.1 hypothetical protein compare
SMa0144 -2.3 -0.4 hypothetical protein compare
SMc02685 -2.3 -2.6 hypothetical protein compare
SMc01258 -2.2 -4.7 hypothetical protein compare
SM_b20280 -2.2 -1.5 hypothetical protein compare
SMc03127 -2.2 -1.6 ABC transporter permease compare
SMc01342 -2.2 -4.7 hypothetical protein compare
SMc01012 -2.2 -1.3 hypothetical protein compare
SMa0149 -2.2 -2.7 transcription elongation factor regulatory protein compare
SMc00876 -2.1 -3.6 ATP-binding MRP protein compare
SM_b21426 -2.1 -6.4 sugar nucleotide oxidoreductaseepimerase compare
SMc01765 -2.1 -1.1 hypothetical protein compare
SMc02102 -2.1 -2.9 hypothetical protein compare
SMc01215 -2.1 -3.9 carbamoyl phosphate synthase large subunit compare
SMa0431 -2.1 -1.1 hypothetical protein compare
SM_b21416 -2.1 -5.5 glucose-1-phosphate cytidylyltransferase compare
SM_b21418 -2.1 -6.0 NDP-hexose 3-C-methyltransferase compare
SMc02631 -2.1 -1.2 hypothetical protein compare
SMc04213 -2.1 -1.5 diacylglycerol kinase compare
SMc02260 -2.1 -1.4 ABC transporter ATP-binding protein compare
SMc02978 -2.0 -4.1 hypothetical protein compare
SMc01569 -2.0 -0.8 carbamoyl phosphate synthase small subunit compare
SMc04085 -2.0 -4.5 hypothetical protein compare
SMa1243 -2.0 -2.8 Azu1 pseudoazurin compare
SMc02713 -1.9 -0.9 RNA polymerase sigma-E factor (sigma-24) protein compare
SM_b21425 -1.9 -5.0 hypothetical protein compare
SMc00514 -1.9 -1.9 monooxygenase compare
SMa0674 -1.9 -1.0 hypothetical protein compare
SMc02714 -1.8 -0.9 hypothetical protein compare
SM_b20580 -1.8 -2.2 LysR family transcriptional regulator compare
SMc00619 -1.8 -1.0 hypothetical protein compare
SM_b20450 -1.8 -7.7 regulatory protein compare
SMc00295 -1.7 -0.6 hypothetical protein compare
SMc00802 -1.7 -0.7 hypothetical protein compare
SMc05020 -1.7 -1.2 entericidin A precursor compare
SM_b21191 -1.7 -3.2 surface saccharide ABC transporter ATP-binding/membrane spanning protein compare
SMc00580 -1.7 -3.1 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc02143 -1.7 -2.6 phosphate ABC transporter permease compare
SMc04121 -1.7 -1.2 uracil phosphoribosyltransferase compare
SMc03774 -1.7 -1.7 hypothetical protein compare
SMc01461 -1.7 -4.0 DNA helicase II protein compare
SMc01933 -1.7 -0.8 hypothetical protein compare
SM_b21213 -1.6 -3.2 serinethreonine protein phosphatase compare
SM_b21058 -1.6 -2.4 glucose-1-phosphate cytidylyltransferase compare
SMc00331 -1.6 -2.3 hypothetical protein compare
SM_b21427 -1.6 -3.3 acetyltransferase compare
SMc02121 -1.6 -1.0 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc00378 -1.6 -2.2 exodeoxyribonuclease VII large subunit compare
SM_b21479 -1.6 -1.1 hypothetical protein compare
SMc02521 -1.6 -2.3 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc00579 -1.6 -2.3 dimethyladenosine transferase compare
SM_b20307 -1.6 -0.7 dihydroxyacetone kinase compare
SMc02266 -1.6 -1.2 hypothetical protein compare
SMc03006 -1.6 -0.8 chemotaxis regulator protein compare
SMc00982 -1.6 -2.6 dioxygenase compare
SM_b20214 -1.6 -4.2 oxidoreductase compare
SMc02799 -1.5 -1.7 16S rRNA methyltransferase GidB compare
SMc01178 -1.5 -1.1 multidrug transmembrane resistance signal peptide protein compare
SMa5014 -1.5 -3.2 hypothetical protein compare
SMc00556 -1.5 -2.7 DNA repair protein RadA compare
SMa0740 -1.5 -1.3 hypothetical protein compare
SMc01880 -1.5 -1.5 pantoate--beta-alanine ligase compare
SMc01801 -1.5 -2.0 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02407 -1.5 -4.5 hypothetical protein compare
SMa5021 -1.5 -2.2 hypothetical protein compare
SMc04296 -1.5 -0.8 cell division protein FtsZ compare
SMa0760 -1.5 -1.4 FixT2 anti-kinase compare
SMc01315 -1.5 -0.8 hypothetical protein compare
SMc01495 -1.5 -2.4 transcriptional regulator compare
SMc02451 -1.5 -1.2 hypothetical protein compare
SM_b20509 -1.5 -1.9 transcriptional regulator compare
SMc01259 -1.5 -2.2 hypothetical protein compare
SM_b20921 -1.5 -1.6 hypothetical protein compare
SMc02894 -1.4 -1.6 hypothetical protein compare
SMc02307 -1.4 -4.2 histidinol dehydrogenase compare
SMc00288 -1.4 -3.1 signal peptide protein compare
SM_b20948 -1.4 -1.0 glucosyltransferase compare
SMc00948 -1.4 -5.3 glutamine synthetase compare
SMc01144 -1.4 -1.8 ribonuclease PH compare
SMc01716 -1.4 -3.0 sensor histidine kinase transmembrane protein compare
SM_b21489 -1.4 -2.9 cytochrome O ubiquinol oxidase subunit III compare
SM_b20258 -1.4 -2.5 transcriptional regulator compare
SMa1929 -1.4 -3.2 hypothetical protein compare
SM_b21523 -1.4 -1.7 cell division inhibitor protein compare
SM_b21035 -1.4 -2.3 hypothetical protein compare
SMa1124 -1.4 -2.0 hypothetical protein compare
SM_b20114 -1.4 -1.6 hypothetical protein compare
SMc02308 -1.4 -2.7 hypothetical protein compare
SMa1239 -1.4 -1.2 NapD component of periplasmic nitrate reductase compare
SMc03180 -1.4 -2.6 monovalent cation/H+ antiporter subunit C compare
SMc00981 -1.4 -2.8 ferredoxin protein compare
SMa0886 -1.3 -1.1 hypothetical protein compare
SMc03226 -1.3 -2.6 hypothetical protein compare
SMc01505 -1.3 -0.9 hypothetical protein compare
SMa1323 -1.3 -1.0 Transcription regulator compare
SMc03871 -1.3 -2.6 ABC transporter ATP-binding protein compare
SM_b20998 -1.3 -3.9 hypothetical protein compare
SMc03053 -1.3 -0.6 flagellar biosynthesis protein FliQ compare
SMc01363 -1.3 -0.6 hypothetical protein compare
SMc04029 -1.3 -1.3 low specificity L-threonine aldolase compare
SM_b20955 -1.3 -2.9 endo-beta-1,3-1,4-glycanase compare
SMc00760 -1.3 -3.1 recombinase A compare
SMc02373 -1.3 -0.9 hypothetical protein compare
SM_b21432 -1.3 -2.1 iron uptake ABC transporter substrate-binding protein precursor compare
SMc02979 -1.3 -3.1 hypothetical protein compare
SMc00557 -1.3 -3.4 alanine racemase compare
SMa0210 -1.3 -3.0 hypothetical protein compare
SMc01341 -1.3 -2.4 hypothetical protein compare
SMc00726 -1.3 -0.7 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc01581 -1.3 -1.9 hypothetical protein compare
SMa2251 -1.3 -2.1 hypothetical protein compare
SM_b20359 -1.3 -2.5 hypothetical protein compare
SM_b20962 -1.3 -1.9 phoshomethylpyrimidine kinase compare
SMc00450 -1.3 -1.0 protoheme IX farnesyltransferase compare
SMa1686 -1.2 -2.2 Two-component response regulator compare
SMc00053 -1.2 -0.6 monovalent cation/H+ antiporter subunit C compare
SMc00854 -1.2 -0.8 hypothetical protein compare
SMc00025 -1.2 -4.5 pyruvate phosphate dikinase compare
SMc03987 -1.2 -4.2 transport transmembrane protein compare
SMa0265 -1.2 -2.2 dehydrogenase compare
SMc00791 -1.2 -0.9 hypothetical protein compare
SMc01110 -1.2 -3.4 DNA-binding protein compare
SMc03993 -1.2 -1.5 hypothetical protein compare
SMc01857 -1.2 -1.8 cell division protein MraZ compare


Specific Phenotypes

For 11 genes in this experiment

For stress Polymyxin B sulfate in Sinorhizobium meliloti 1021

For stress Polymyxin B sulfate across organisms