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Experiment set4IT049 for
Methanococcus maripaludis S2
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Formate McCas deepwell complete
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06680
-8.2
-15.8
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06700
-7.7
-19.2
hypothetical protein
compare
MMP
_RS05515
-7.1
-10.2
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06685
-6.9
-16.5
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS01175
-6.8
-7.8
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06350
-6.4
-10.8
HesA/MoeB/ThiF family protein
compare
MMP
_RS01020
-6.3
-1.9
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS06400
-6.0
-3.6
4Fe-4S binding protein
compare
MMP
_RS03315
-6.0
-3.1
ferrous iron transport protein A
compare
MMP
_RS01500
-6.0
-4.3
CBS domain-containing protein
compare
MMP
_RS06345
-5.9
-12.6
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS07845
-5.9
-6.2
LL-diaminopimelate aminotransferase
compare
MMP
_RS00305
-5.8
-3.9
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS03015
-5.6
-13.2
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06715
-5.4
-21.3
cache domain-containing protein
compare
MMP
_RS06625
-5.4
-4.8
DNA primase
compare
MMP
_RS06285
-5.3
-4.9
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06295
-5.3
-11.3
methanogenesis marker 14 protein
compare
MMP
_RS06370
-5.3
-7.6
biotin synthase BioB
compare
MMP
_RS04685
-5.1
-6.0
DUF126 domain-containing protein
compare
MMP
_RS08820
-5.1
-10.9
hypothetical protein
compare
MMP
_RS01755
-5.1
-2.2
DUF2097 domain-containing protein
compare
MMP
_RS07005
-5.0
-1.5
4Fe-4S binding protein
compare
MMP
_RS06355
-5.0
-4.4
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS08715
-5.0
-4.5
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS01225
-4.9
-8.0
DUF5379 domain-containing protein
compare
MMP
_RS08300
-4.9
-2.5
metal-sulfur cluster assembly factor
compare
MMP
_RS03035
-4.8
-7.7
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS04500
-4.8
-20.3
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS00685
-4.8
-8.7
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS06630
-4.7
-2.0
UPF0058 family protein
compare
MMP
_RS08650
-4.7
-6.3
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS06230
-4.7
-5.9
helix-turn-helix domain-containing protein
compare
MMP
_RS06705
-4.6
-8.1
formate/nitrite transporter family protein
compare
MMP
_RS04605
-4.6
-8.9
cobalt ECF transporter T component CbiQ
compare
MMP
_RS07635
-4.5
-10.1
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS01800
-4.4
-7.1
TIGR00303 family protein
compare
MMP
_RS01005
-4.4
-3.2
riboflavin synthase
compare
MMP
_RS08095
-4.4
-9.1
dethiobiotin synthase
compare
MMP
_RS08635
-4.3
-4.7
UbiA family prenyltransferase
compare
MMP
_RS08100
-4.3
-13.5
8-amino-7-oxononanoate synthase
compare
MMP
_RS06720
-4.3
-13.4
response regulator transcription factor
compare
MMP
_RS04775
-4.3
-7.2
adenosylhomocysteinase
compare
MMP
_RS00695
-4.2
-1.8
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS01325
-4.2
-4.1
dihydroneopterin aldolase family protein
compare
MMP
_RS07445
-4.2
-7.5
helix-turn-helix domain-containing protein
compare
MMP
_RS08460
-4.2
-4.4
proteasome-activating nucleotidase
compare
MMP
_RS07195
-4.1
-15.2
M20 family metallo-hydrolase
compare
MMP
_RS04585
-4.1
-11.8
AIR synthase related protein
compare
MMP
_RS08105
-4.1
-9.4
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS03600
-4.1
-5.0
triose-phosphate isomerase
compare
MMP
_RS07545
-4.1
-2.4
HTH domain-containing protein
compare
MMP
_RS04780
-4.1
-6.6
ribonuclease P
compare
MMP
_RS04890
-4.0
-1.7
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS07735
-4.0
-1.7
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS06340
-4.0
-11.1
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS00895
-4.0
-9.3
hypothetical protein
compare
MMP
_RS06120
-4.0
-5.2
UPF0147 family protein
compare
MMP
_RS06270
-3.9
-10.2
TIGR00300 family protein
compare
MMP
_RS02900
-3.9
-1.7
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS06895
-3.9
-2.7
selenocysteine-specific translation elongation factor
compare
MMP
_RS03400
-3.9
-4.2
archease
compare
MMP
_RS07645
-3.8
-14.0
aldehyde dehydrogenase family protein
compare
MMP
_RS03025
-3.8
-7.4
molybdenum cofactor guanylyltransferase
compare
MMP
_RS06475
-3.8
-6.7
FAD-dependent oxidoreductase
compare
MMP
_RS02240
-3.8
-5.4
methanogenesis marker 7 protein
compare
MMP
_RS02195
-3.8
-5.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS03640
-3.7
-7.4
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08645
-3.7
-14.2
UPF0179 family protein
compare
MMP
_RS03580
-3.7
-4.8
signal recognition particle-docking protein FtsY
compare
MMP
_RS01795
-3.6
-3.3
methanogenesis marker 6 protein
compare
MMP
_RS04615
-3.6
-6.9
PDGLE domain-containing protein
compare
MMP
_RS06020
-3.6
-8.1
archaeoflavoprotein AfpA
compare
MMP
_RS02280
-3.6
-2.1
DUF211 domain-containing protein
compare
MMP
_RS00110
-3.5
-6.5
hypothetical protein
compare
MMP
_RS02875
-3.5
-17.6
chorismate pyruvate-lyase family protein
compare
MMP
_RS02355
-3.4
-5.7
30S ribosomal protein S27ae
compare
MMP
_RS08720
-3.4
-4.0
4Fe-4S binding protein
compare
MMP
_RS08790
-3.4
-4.9
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS04620
-3.4
-13.1
cobalt transporter CbiM
compare
MMP
_RS06885
-3.4
-5.6
50S ribosome-binding GTPase
compare
MMP
_RS02135
-3.3
-7.3
DUF5612 domain-containing protein
compare
MMP
_RS01985
-3.3
-12.5
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS01380
-3.3
-6.9
PHP domain-containing protein
compare
MMP
_RS08745
-3.3
-10.4
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS07380
-3.3
-3.9
transcription elongation factor Spt5
compare
MMP
_RS09020
-3.3
-3.1
hypothetical protein
compare
MMP
_RS08435
-3.3
-5.1
Era-like GTP-binding protein
compare
MMP
_RS00300
-3.2
-1.6
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS07605
-3.2
-5.2
diadenylate cyclase
compare
MMP
_RS01220
-3.1
-10.1
hypothetical protein
compare
MMP
_RS00515
-3.1
-2.2
DUF655 domain-containing protein
compare
MMP
_RS06975
-3.1
-5.5
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS06925
-3.1
-4.5
ribonuclease VapC4
compare
MMP
_RS01265
-3.0
-2.7
hypothetical protein
compare
MMP
_RS02145
-3.0
-7.6
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03155
-2.9
-13.0
precorrin-6A reductase
compare
MMP
_RS07580
-2.9
-4.0
DUF356 domain-containing protein
compare
MMP
_RS00295
-2.9
-5.7
gamma carbonic anhydrase family protein
compare
MMP
_RS03960
-2.8
-2.0
hypothetical protein
compare
MMP
_RS07630
-2.8
-1.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS03445
-2.8
-2.3
methanogenesis marker 17 protein
compare
MMP
_RS07525
-2.8
-9.4
4Fe-4S binding protein
compare
MMP
_RS03435
-2.7
-4.2
ketol-acid reductoisomerase
compare
MMP
_RS01700
-2.7
-2.5
dihydroxy-acid dehydratase
compare
MMP
_RS01610
-2.7
-5.6
hypothetical protein
compare
MMP
_RS02345
-2.7
-5.5
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS07730
-2.7
-3.5
pyruvate synthase subunit beta
compare
MMP
_RS05345
-2.7
-8.2
hypothetical protein
compare
MMP
_RS00115
-2.7
-16.2
radical SAM protein
compare
MMP
_RS01385
-2.7
-1.6
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS07600
-2.6
-3.1
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS07575
-2.6
-4.8
RNA ligase partner protein
compare
MMP
_RS05845
-2.6
-3.2
tRNA-intron lyase
compare
MMP
_RS08445
-2.5
-7.5
DUF2099 family protein
compare
MMP
_RS08210
-2.5
-4.5
phosphatidylglycerophosphatase A
compare
MMP
_RS05550
-2.5
-1.5
cation:proton antiporter
compare
MMP
_RS05920
-2.5
-1.4
50S ribosomal protein L37e
compare
MMP
_RS07200
-2.4
-8.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS02165
-2.4
-13.9
tRNA-dihydrouridine synthase
compare
MMP
_RS08440
-2.4
-4.2
cell division protein SepF
compare
MMP
_RS06315
-2.3
-2.4
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS01725
-2.3
-5.0
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS06215
-2.2
-6.5
30S ribosomal protein S6e
compare
MMP
_RS05430
-2.2
-4.9
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS07390
-2.2
-2.4
cell division protein FtsZ
compare
MMP
_RS07755
-2.2
-2.3
DUF555 domain-containing protein
compare
MMP
_RS06105
-2.1
-11.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS02010
-2.1
-12.5
PHP domain-containing protein
compare
MMP
_RS06930
-2.1
-12.6
MBL fold metallo-hydrolase
compare
MMP
_RS07685
-2.1
-11.3
TIGR01212 family radical SAM protein
compare
MMP
_RS06730
-2.0
-1.7
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01365
-2.0
-2.2
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS05540
-2.0
-3.0
hypothetical protein
compare
MMP
_RS02235
-2.0
-10.0
CBS domain-containing protein
compare
MMP
_RS01980
-2.0
-14.6
trimeric intracellular cation channel family protein
compare
MMP
_RS05440
-2.0
-10.7
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05875
-2.0
-4.0
hydroxyethylthiazole kinase
compare
MMP
_RS07750
-2.0
-7.1
DUF357 domain-containing protein
compare
MMP
_RS05265
-2.0
-3.3
2-isopropylmalate synthase
compare
MMP
_RS04710
-2.0
-2.7
hypothetical protein
compare
MMP
_RS01830
-2.0
-3.2
tRNA-Val
compare
MMP
_RS00050
-1.9
-8.7
AarF/UbiB family protein
compare
MMP
_RS00320
-1.9
-3.3
class I SAM-dependent methyltransferase
compare
MMP
_RS02175
-1.9
-1.8
DUF1611 domain-containing protein
compare
MMP
_RS07385
-1.9
-2.3
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS02190
-1.8
-3.8
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS03095
-1.8
-6.5
diphthine synthase
compare
MMP
_RS01250
-1.8
-8.3
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS05930
-1.8
-4.1
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS01665
-1.8
-2.8
DUF2111 domain-containing protein
compare
MMP
_RS03205
-1.7
-2.3
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS02800
-1.7
-6.6
nucleotidyltransferase domain-containing protein
compare
MMP
_RS00290
-1.7
-7.2
hypothetical protein
compare
MMP
_RS00040
-1.7
-6.5
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS01840
-1.7
-10.7
TIGR00289 family protein
compare
MMP
_RS06865
-1.7
-1.9
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS00985
-1.7
-6.8
CDC48 family AAA ATPase
compare
MMP
_RS03475
-1.6
-1.2
hypothetical protein
compare
MMP
_RS05815
-1.6
-2.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS00450
-1.6
-2.5
4Fe-4S binding protein
compare
MMP
_RS00900
-1.6
-3.9
50S ribosomal protein L39e
compare
MMP
_RS03700
-1.6
-7.2
sodium:proton antiporter
compare
MMP
_RS07425
-1.6
-5.3
GTP-binding protein
compare
MMP
_RS03140
-1.6
-10.8
hypothetical protein
compare
MMP
_RS05765
-1.5
-8.5
M42 family metallopeptidase
compare
MMP
_RS06940
-1.5
-2.7
polyprenyl diphosphate synthase
compare
MMP
_RS06110
-1.5
-5.2
ATP-dependent protease LonB
compare
MMP
_RS04870
-1.5
-4.9
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS03145
-1.5
-8.0
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS07420
-1.5
-3.4
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS00750
-1.5
-3.5
fumarate hydratase
compare
MMP
_RS03250
-1.5
-3.0
MJ1244 family protein
compare
MMP
_RS05250
-1.4
-2.3
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS05425
-1.4
-6.1
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS05245
-1.4
-9.3
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS01475
-1.4
-8.6
phosphosulfolactate synthase
compare
MMP
_RS07790
-1.4
-8.9
segregation/condensation protein A
compare
MMP
_RS07365
-1.4
-9.6
2-phosphoglycerate kinase
compare
MMP
_RS05925
-1.4
-3.2
small nuclear ribonucleoprotein
compare
MMP
_RS08840
-1.4
-8.7
class I SAM-dependent methyltransferase
compare
MMP
_RS07700
-1.3
-8.1
DUF1188 domain-containing protein
compare
MMP
_RS01335
-1.3
-4.2
prefoldin subunit beta
compare
MMP
_RS00720
-1.3
-6.2
metal-dependent hydrolase
compare
MMP
_RS08330
-1.3
-5.7
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS05545
-1.3
-6.5
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS04850
-1.3
-10.6
UPF0254 family protein
compare
MMP
_RS08690
-1.3
-10.5
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
compare
MMP
_RS05555
-1.3
-2.1
DUF4040 domain-containing protein
compare
MMP
_RS00725
-1.2
-6.9
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS00620
-1.2
-7.3
4Fe-4S binding protein
compare
MMP
_RS06395
-1.2
-4.4
ThiF family adenylyltransferase
compare
MMP
_RS07955
-1.2
-4.1
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS05090
-1.2
-6.7
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS06980
-1.2
-7.4
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS02110
-1.2
-1.6
hypothetical protein
compare
MMP
_RS03110
-1.2
-5.9
glycosyltransferase family 2 protein
compare
MMP
_RS06200
-1.2
-8.5
M24 family metallopeptidase
compare
MMP
_RS00730
-1.2
-5.8
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS06130
-1.1
-3.7
peptidylprolyl isomerase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t2 experiments