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Experiment set4IT048 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS03620
+2.5
14.3
hypothetical protein
compare
MMP
_RS03615
+2.4
17.4
4Fe-4S binding protein
compare
MMP
_RS00240
+1.5
12.7
type II secretion system F family protein
compare
MMP
_RS01310
+1.5
10.7
hypothetical protein
compare
MMP
_RS01280
+1.5
11.3
DUF515 domain-containing protein
compare
MMP
_RS03385
+1.4
2.2
cation diffusion facilitator family transporter
compare
MMP
_RS08855
+1.4
9.8
hypothetical protein
compare
MMP
_RS04550
+1.4
12.0
S-layer protein
compare
MMP
_RS01285
+1.4
9.8
hypothetical protein
compare
MMP
_RS01290
+1.3
8.2
class III signal peptide-containing protein
compare
MMP
_RS09055
+1.3
2.0
CAP domain-containing protein
compare
MMP
_RS01305
+1.3
11.0
hypothetical protein
compare
MMP
_RS03090
+1.3
6.0
cation:proton antiporter
compare
MMP
_RS06840
+1.3
1.9
DNA-directed RNA polymerase subunit N
compare
MMP
_RS01295
+1.3
9.0
hypothetical protein
compare
MMP
_RS08860
+1.3
5.4
MinD/ParA family protein
compare
MMP
_RS00250
+1.3
10.2
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS00245
+1.2
10.5
type II secretion system F family protein
compare
MMP
_RS08665
+1.2
10.5
hypothetical protein
compare
MMP
_RS01370
+1.2
6.8
acetate--CoA ligase family protein
compare
MMP
_RS09045
+1.1
7.5
class III signal peptide-containing protein
compare
MMP
_RS01570
+1.1
2.5
hypothetical protein
compare
MMP
_RS03125
+1.1
4.4
cell division ATPase MinD
compare
MMP
_RS07120
+1.0
6.1
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS01525
+1.0
2.6
nucleoside-diphosphate kinase
compare
MMP
_RS01315
+1.0
8.5
DUF2341 domain-containing protein
compare
MMP
_RS07135
+1.0
5.6
coenzyme F420 hydrogenase subunit beta
compare
MMP
_RS08580
+1.0
2.9
flagellin
compare
MMP
_RS01270
+0.9
6.3
prepilin peptidase
compare
MMP
_RS02675
+0.9
1.3
hypothetical protein
compare
MMP
_RS08940
+0.8
1.5
MetS family NSS transporter small subunit
compare
MMP
_RS00140
+0.8
4.2
DUF192 domain-containing protein
compare
MMP
_RS02415
+0.8
1.6
site-specific integrase
compare
MMP
_RS08675
+0.8
1.9
class III signal peptide-containing protein
compare
MMP
_RS08775
+0.8
3.2
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS06600
+0.8
0.6
class III signal peptide-containing protein
compare
MMP
_RS07130
+0.8
4.6
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS06540
+0.7
2.2
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS09025
+0.7
1.1
hypothetical protein
compare
MMP
_RS07890
+0.7
2.2
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS05675
+0.7
2.3
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS01300
+0.7
4.8
hypothetical protein
compare
MMP
_RS07805
+0.7
4.1
ABC transporter permease
compare
MMP
_RS01655
+0.7
3.2
DsrE family protein
compare
MMP
_RS05825
+0.7
2.7
peptidyl-prolyl cis-trans isomerase
compare
MMP
_RS08275
+0.7
4.7
hypothetical protein
compare
MMP
_RS07125
+0.7
2.1
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS08980
+0.7
2.0
hypothetical protein
compare
MMP
_RS06870
+0.7
3.0
DedA family protein
compare
MMP
_RS08930
+0.6
1.7
hypothetical protein
compare
MMP
_RS08615
+0.6
1.7
flagellar protein G
compare
MMP
_RS06175
+0.6
4.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05910
+0.6
2.1
cell division ATPase MinD
compare
MMP
_RS07765
+0.6
3.0
sodium:alanine symporter family protein
compare
MMP
_RS01320
+0.6
1.7
hypothetical protein
compare
MMP
_RS05985
+0.6
1.6
hypothetical protein
compare
MMP
_RS03340
+0.6
0.7
ABC transporter ATP-binding protein
compare
MMP
_RS08400
+0.6
2.4
MJ0307 family thioredoxin
compare
MMP
_RS08285
+0.6
2.6
serine/threonine protein kinase
compare
MMP
_RS01275
+0.5
3.1
class III signal peptide-containing protein
compare
MMP
_RS05785
+0.5
4.2
ATP-binding protein
compare
MMP
_RS07180
+0.5
2.3
DEAD/DEAH box helicase
compare
MMP
_RS01965
+0.5
1.1
DUF1616 domain-containing protein
compare
MMP
_RS06225
+0.5
2.3
DNA double-strand break repair nuclease NurA
compare
MMP
_RS07840
+0.5
1.9
ribonuclease III
compare
MMP
_RS03320
+0.5
1.8
metal-dependent transcriptional regulator
compare
MMP
_RS08670
+0.5
2.2
metallophosphoesterase
compare
MMP
_RS06140
+0.5
2.9
radical SAM protein
compare
MMP
_RS01085
+0.5
1.2
hypothetical protein
compare
MMP
_RS06550
+0.5
2.1
AMP-binding protein
compare
MMP
_RS08385
+0.5
2.7
ABC transporter substrate-binding protein
compare
MMP
_RS00395
+0.5
1.0
MGMT family protein
compare
MMP
_RS08290
+0.5
2.7
DNA-binding protein Alba
compare
MMP
_RS02405
+0.5
1.9
hypothetical protein
compare
MMP
_RS08850
+0.5
3.8
hypothetical protein
compare
MMP
_RS05635
+0.5
3.2
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS07330
+0.5
3.5
membrane protein
compare
MMP
_RS06525
+0.5
0.8
YciI family protein
compare
MMP
_RS01210
+0.5
2.3
sodium:solute symporter
compare
MMP
_RS02745
+0.5
0.8
hypothetical protein
compare
MMP
_RS00975
+0.4
3.3
HD domain-containing protein
compare
MMP
_RS07795
+0.4
2.6
site-2 protease family protein
compare
MMP
_RS08620
+0.4
2.3
flagellar accessory protein FlaH
compare
MMP
_RS02765
+0.4
1.5
ABC transporter ATP-binding protein
compare
MMP
_RS07570
+0.4
2.9
nucleotidyltransferase family protein
compare
MMP
_RS07900
+0.4
1.0
YeeE/YedE family protein
compare
MMP
_RS08480
+0.4
2.7
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS00965
+0.4
1.4
hypothetical protein
compare
MMP
_RS01620
+0.4
1.1
hypothetical protein
compare
MMP
_RS01165
+0.4
2.5
DUF434 domain-containing protein
compare
MMP
_RS08130
+0.4
3.0
IGHMBP2 family helicase
compare
MMP
_RS05720
+0.4
1.2
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS07850
+0.4
1.3
prephenate dehydratase
compare
MMP
_RS08325
+0.4
3.0
hypothetical protein
compare
MMP
_RS08610
+0.4
2.4
flagellar protein F
compare
MMP
_RS07095
+0.4
1.0
PspC domain-containing protein
compare
MMP
_RS08500
+0.4
1.9
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS02450
+0.4
1.3
hypothetical protein
compare
MMP
_RS07775
+0.4
1.4
alanine dehydrogenase
compare
MMP
_RS08160
+0.4
1.9
EamA family transporter
compare
MMP
_RS06500
+0.4
2.9
ATP-binding protein
compare
MMP
_RS04610
+0.4
1.7
Dabb family protein
compare
MMP
_RS05315
+0.4
0.7
hypothetical protein
compare
MMP
_RS02310
+0.4
0.8
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMP
_RS04030
+0.4
1.4
hypothetical protein
compare
MMP
_RS00675
+0.4
0.5
nitroreductase family protein
compare
MMP
_RS00705
+0.4
0.8
hypothetical protein
compare
MMP
_RS06325
+0.4
0.8
hypothetical protein
compare
MMP
_RS06070
+0.4
2.8
iron ABC transporter substrate-binding protein
compare
MMP
_RS04035
+0.4
0.8
hypothetical protein
compare
MMP
_RS05035
+0.4
2.0
hypothetical protein
compare
MMP
_RS06545
+0.4
1.5
ferredoxin family protein
compare
MMP
_RS07770
+0.4
1.4
alanine racemase
compare
MMP
_RS02985
+0.4
0.8
hypothetical protein
compare
MMP
_RS07085
+0.4
2.3
ribonuclease HII
compare
MMP
_RS07680
+0.4
1.5
DUF366 family protein
compare
MMP
_RS01255
+0.4
1.9
amino acid ABC transporter ATP-binding protein
compare
MMP
_RS02595
+0.4
0.7
putative zinc-binding protein
compare
MMP
_RS03625
+0.4
2.1
cell wall-binding protein
compare
MMP
_RS07550
+0.4
2.6
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS06905
+0.4
0.8
hypothetical protein
compare
MMP
_RS07855
+0.4
2.0
class I SAM-dependent methyltransferase
compare
MMP
_RS06920
+0.4
1.8
AAA family ATPase
compare
MMP
_RS02635
+0.4
2.4
class I SAM-dependent methyltransferase
compare
MMP
_RS02365
+0.4
1.8
nitrogen fixation
compare
MMP
_RS07925
+0.4
1.1
haloacid dehalogenase
compare
MMP
_RS05490
+0.4
2.0
IMPACT family protein
compare
MMP
_RS00655
+0.3
1.2
hypothetical protein
compare
MMP
_RS00185
+0.3
2.4
potassium channel protein
compare
MMP
_RS03965
+0.3
1.0
hypothetical protein
compare
MMP
_RS00660
+0.3
2.0
alkaline phosphatase family protein
compare
MMP
_RS00990
+0.3
0.9
hypothetical protein
compare
MMP
_RS06990
+0.3
1.3
CatB-related O-acetyltransferase
compare
MMP
_RS05695
+0.3
1.4
phospholipase D-like domain-containing protein
compare
MMP
_RS02370
+0.3
1.1
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS05670
+0.3
2.6
phosphate ABC transporter permease PstA
compare
MMP
_RS01130
+0.3
1.8
flavoprotein
compare
MMP
_RS04205
+0.3
1.2
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS09030
+0.3
1.9
hypothetical protein
compare
MMP
_RS08630
+0.3
1.6
archaellar assembly protein FlaJ
compare
MMP
_RS06875
+0.3
1.3
FAD-dependent oxidoreductase
compare
MMP
_RS02475
+0.3
1.2
hypothetical protein
compare
MMP
_RS08250
+0.3
1.8
pyruvate kinase
compare
MMP
_RS01095
+0.3
1.2
iron ABC transporter permease
compare
MMP
_RS03120
+0.3
0.9
hypothetical protein
compare
MMP
_RS04530
+0.3
1.6
ABC transporter permease
compare
MMP
_RS01080
+0.3
1.3
DUF2202 domain-containing protein
compare
MMP
_RS02175
+0.3
0.3
DUF1611 domain-containing protein
compare
MMP
_RS08265
+0.3
1.0
rubrerythrin
compare
MMP
_RS08395
+0.3
1.7
DsrE family protein
compare
MMP
_RS06250
+0.3
1.4
hypothetical protein
compare
MMP
_RS08245
+0.3
1.6
DUF4013 domain-containing protein
compare
MMP
_RS08090
+0.3
1.2
hypothetical protein
compare
MMP
_RS01125
+0.3
1.2
thioredoxin family protein
compare
MMP
_RS01790
+0.3
1.5
restriction endonuclease
compare
MMP
_RS06970
+0.3
1.5
ribosomal protein S18-alanine N-acetyltransferase
compare
MMP
_RS01870
+0.3
1.7
acyl-CoA dehydratase activase
compare
MMP
_RS08080
+0.3
1.5
YchF/TatD family DNA exonuclease
compare
MMP
_RS04410
+0.3
1.3
hypothetical protein
compare
MMP
_RS06075
+0.3
1.3
class I SAM-dependent methyltransferase
compare
MMP
_RS02540
+0.3
1.1
DUF2283 domain-containing protein
compare
MMP
_RS07915
+0.3
1.3
DUF4870 domain-containing protein
compare
MMP
_RS02770
+0.3
1.4
hypothetical protein
compare
MMP
_RS04445
+0.3
1.4
P-II family nitrogen regulator
compare
MMP
_RS06910
+0.3
1.5
RlmF-related methyltransferase
compare
MMP
_RS05940
+0.3
1.2
corrinoid protein
compare
MMP
_RS01495
+0.3
1.7
TraB/GumN family protein
compare
MMP
_RS00865
+0.3
1.1
SLC13 family permease
compare
MMP
_RS03070
+0.3
0.9
AzlD domain-containing protein
compare
MMP
_RS05990
+0.2
0.9
DsrE family protein
compare
MMP
_RS06045
+0.2
1.6
DNA polymerase
compare
MMP
_RS05665
+0.2
0.9
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS01435
+0.2
1.4
DMT family transporter
compare
MMP
_RS03150
+0.2
1.4
phosphoglycerate mutase
compare
MMP
_RS03220
+0.2
0.6
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS08410
+0.2
1.2
DUF169 domain-containing protein
compare
MMP
_RS07650
+0.2
1.5
TldD/PmbA family protein
compare
MMP
_RS01160
+0.2
1.3
DMT family transporter
compare
MMP
_RS05820
+0.2
1.2
RNA-binding transcriptional accessory protein
compare
MMP
_RS00150
+0.2
1.2
AAA family ATPase
compare
MMP
_RS01055
+0.2
0.9
hypothetical protein
compare
MMP
_RS03820
+0.2
1.1
EamA family transporter
compare
MMP
_RS00960
+0.2
0.7
iron export ABC transporter permease subunit FetB
compare
MMP
_RS01650
+0.2
0.3
sulfurtransferase TusA family protein
compare
MMP
_RS05835
+0.2
0.2
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMP
_RS01785
+0.2
1.4
hypothetical protein
compare
MMP
_RS07835
+0.2
1.1
TldD/PmbA family protein
compare
MMP
_RS06150
+0.2
1.5
hypothetical protein
compare
MMP
_RS04735
+0.2
0.8
tautomerase family protein
compare
MMP
_RS08770
+0.2
1.4
hypothetical protein
compare
MMP
_RS04125
+0.2
1.1
TetR/AcrR family transcriptional regulator
compare
MMP
_RS02965
+0.2
1.1
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS07715
+0.2
1.6
YfcE family phosphodiesterase
compare
MMP
_RS01515
+0.2
1.6
PINc/VapC family ATPase
compare
MMP
_RS07640
+0.2
1.2
mechanosensitive ion channel family protein
compare
MMP
_RS08535
+0.2
0.9
bis-aminopropyl spermidine synthase family protein
compare
MMP
_RS04090
+0.2
0.5
hypothetical protein
compare
MMP
_RS04945
+0.2
1.0
hypothetical protein
compare
MMP
_RS03550
+0.2
0.6
DUF2124 domain-containing protein
compare
MMP
_RS07150
+0.2
1.0
MTH895/ArsE family thioredoxin-like protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t2 experiments