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Experiment set4IT046 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS05500
-8.1
-7.0
2-isopropylmalate synthase
compare
MMP
_RS06975
-7.9
-1.8
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS06285
-7.6
-2.0
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS07845
-7.3
-2.2
LL-diaminopimelate aminotransferase
compare
MMP
_RS06400
-7.1
-1.6
4Fe-4S binding protein
compare
MMP
_RS01455
-7.0
-5.5
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS04615
-7.0
-3.0
PDGLE domain-containing protein
compare
MMP
_RS01175
-6.9
-3.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS03450
-6.9
-2.0
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS07345
-6.4
-5.2
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS04620
-6.3
-12.1
cobalt transporter CbiM
compare
MMP
_RS01545
-6.2
-0.8
CBS domain-containing protein
compare
MMP
_RS03435
-6.1
-1.6
ketol-acid reductoisomerase
compare
MMP
_RS04685
-6.0
-2.8
DUF126 domain-containing protein
compare
MMP
_RS02195
-5.9
-3.7
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS08210
-5.9
-2.1
phosphatidylglycerophosphatase A
compare
MMP
_RS01020
-5.9
-0.8
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS07630
-5.7
-1.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS03600
-5.6
-2.2
triose-phosphate isomerase
compare
MMP
_RS03315
-5.6
-1.2
ferrous iron transport protein A
compare
MMP
_RS01830
-5.5
-1.0
tRNA-Val
compare
MMP
_RS04605
-5.4
-4.0
cobalt ECF transporter T component CbiQ
compare
MMP
_RS05265
-5.4
-1.7
2-isopropylmalate synthase
compare
MMP
_RS06230
-5.3
-1.8
helix-turn-helix domain-containing protein
compare
MMP
_RS05070
-5.2
-8.4
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS00305
-5.2
-1.5
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS05930
-5.2
-2.4
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS02135
-5.1
-4.8
DUF5612 domain-containing protein
compare
MMP
_RS04215
-5.1
-6.0
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS05085
-5.0
-10.1
AAA family ATPase
compare
MMP
_RS00750
-5.0
-2.3
fumarate hydratase
compare
MMP
_RS05100
-4.9
-21.1
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS02900
-4.9
-0.6
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS04500
-4.8
-16.2
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS06270
-4.8
-6.2
TIGR00300 family protein
compare
MMP
_RS05075
-4.7
-18.1
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS08745
-4.7
-6.7
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS05060
-4.7
-10.6
AAA family ATPase
compare
MMP
_RS03445
-4.7
-0.9
methanogenesis marker 17 protein
compare
MMP
_RS04780
-4.7
-2.8
ribonuclease P
compare
MMP
_RS06120
-4.7
-2.0
UPF0147 family protein
compare
MMP
_RS00300
-4.7
-0.6
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS08715
-4.7
-1.9
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS05080
-4.6
-12.3
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS07005
-4.6
-0.6
4Fe-4S binding protein
compare
MMP
_RS09020
-4.6
-1.7
hypothetical protein
compare
MMP
_RS03475
-4.6
-0.6
hypothetical protein
compare
MMP
_RS06895
-4.6
-1.7
selenocysteine-specific translation elongation factor
compare
MMP
_RS05090
-4.6
-10.8
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS01385
-4.6
-0.6
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS07185
-4.5
-10.8
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS05920
-4.5
-0.6
50S ribosomal protein L37e
compare
MMP
_RS07390
-4.5
-2.3
cell division protein FtsZ
compare
MMP
_RS07380
-4.5
-2.0
transcription elongation factor Spt5
compare
MMP
_RS02145
-4.5
-8.9
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03700
-4.4
-11.1
sodium:proton antiporter
compare
MMP
_RS01005
-4.4
-1.1
riboflavin synthase
compare
MMP
_RS05095
-4.4
-6.4
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS06370
-4.4
-4.8
biotin synthase BioB
compare
MMP
_RS03640
-4.4
-3.6
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS02240
-4.4
-3.5
methanogenesis marker 7 protein
compare
MMP
_RS07545
-4.3
-0.8
HTH domain-containing protein
compare
MMP
_RS06375
-4.3
-5.3
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS08105
-4.2
-7.5
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS06730
-4.2
-2.0
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS08095
-4.2
-6.9
dethiobiotin synthase
compare
MMP
_RS04710
-4.2
-1.5
hypothetical protein
compare
MMP
_RS08720
-4.2
-1.5
4Fe-4S binding protein
compare
MMP
_RS01700
-4.2
-0.8
dihydroxy-acid dehydratase
compare
MMP
_RS08650
-4.1
-3.2
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS05925
-4.1
-3.5
small nuclear ribonucleoprotein
compare
MMP
_RS08300
-4.1
-0.9
metal-sulfur cluster assembly factor
compare
MMP
_RS01925
-4.1
-10.8
DUF1616 domain-containing protein
compare
MMP
_RS08635
-4.0
-1.8
UbiA family prenyltransferase
compare
MMP
_RS05065
-4.0
-3.9
CooT family nickel-binding protein
compare
MMP
_RS00515
-3.9
-0.7
DUF655 domain-containing protein
compare
MMP
_RS06885
-3.9
-2.6
50S ribosome-binding GTPase
compare
MMP
_RS08100
-3.9
-5.9
8-amino-7-oxononanoate synthase
compare
MMP
_RS07645
-3.9
-6.8
aldehyde dehydrogenase family protein
compare
MMP
_RS00695
-3.9
-0.7
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS01955
-3.8
-2.8
hypothetical protein
compare
MMP
_RS03015
-3.8
-9.6
GTP 3' 8-cyclase MoaA
compare
MMP
_RS05425
-3.8
-5.1
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS03580
-3.7
-3.7
signal recognition particle-docking protein FtsY
compare
MMP
_RS05515
-3.7
-7.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS01800
-3.7
-3.6
TIGR00303 family protein
compare
MMP
_RS07635
-3.7
-5.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS06475
-3.6
-5.0
FAD-dependent oxidoreductase
compare
MMP
_RS05055
-3.6
-12.8
DUF166 domain-containing protein
compare
MMP
_RS06315
-3.6
-0.9
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS03025
-3.6
-5.3
molybdenum cofactor guanylyltransferase
compare
MMP
_RS07730
-3.6
-1.7
pyruvate synthase subunit beta
compare
MMP
_RS06350
-3.6
-6.2
HesA/MoeB/ThiF family protein
compare
MMP
_RS07735
-3.6
-0.6
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01225
-3.5
-5.0
DUF5379 domain-containing protein
compare
MMP
_RS03035
-3.5
-3.5
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS07600
-3.5
-2.6
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06295
-3.4
-7.0
methanogenesis marker 14 protein
compare
MMP
_RS05550
-3.4
-0.6
cation:proton antiporter
compare
MMP
_RS07195
-3.4
-8.7
M20 family metallo-hydrolase
compare
MMP
_RS03140
-3.4
-13.1
hypothetical protein
compare
MMP
_RS04720
-3.4
-2.8
DedA family protein
compare
MMP
_RS06355
-3.4
-2.2
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS08240
-3.4
-5.8
methanogenesis marker 16 metalloprotein
compare
MMP
_RS02875
-3.4
-10.8
chorismate pyruvate-lyase family protein
compare
MMP
_RS07580
-3.3
-3.0
DUF356 domain-containing protein
compare
MMP
_RS00110
-3.3
-3.0
hypothetical protein
compare
MMP
_RS08790
-3.3
-2.1
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS04775
-3.3
-3.8
adenosylhomocysteinase
compare
MMP
_RS06340
-3.3
-6.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS02280
-3.2
-0.8
DUF211 domain-containing protein
compare
MMP
_RS04790
-3.2
-12.4
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS01905
-3.1
-12.1
glycosyltransferase
compare
MMP
_RS04890
-3.1
-0.8
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS07955
-3.1
-5.7
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS08330
-3.1
-4.3
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS02010
-3.1
-8.6
PHP domain-containing protein
compare
MMP
_RS07555
-3.0
-0.7
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS06930
-3.0
-13.1
MBL fold metallo-hydrolase
compare
MMP
_RS06020
-3.0
-3.6
archaeoflavoprotein AfpA
compare
MMP
_RS03145
-3.0
-6.1
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS00685
-2.9
-3.3
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS03960
-2.9
-0.8
hypothetical protein
compare
MMP
_RS08440
-2.9
-2.3
cell division protein SepF
compare
MMP
_RS03420
-2.9
-3.3
acetolactate synthase small subunit
compare
MMP
_RS08460
-2.9
-2.4
proteasome-activating nucleotidase
compare
MMP
_RS01265
-2.9
-1.8
hypothetical protein
compare
MMP
_RS01755
-2.9
-1.1
DUF2097 domain-containing protein
compare
MMP
_RS05250
-2.8
-1.4
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS07575
-2.7
-3.8
RNA ligase partner protein
compare
MMP
_RS06630
-2.7
-1.0
UPF0058 family protein
compare
MMP
_RS07365
-2.7
-9.4
2-phosphoglycerate kinase
compare
MMP
_RS01900
-2.7
-11.6
hypothetical protein
compare
MMP
_RS01910
-2.6
-9.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS07755
-2.6
-0.9
DUF555 domain-containing protein
compare
MMP
_RS06130
-2.6
-3.5
peptidylprolyl isomerase
compare
MMP
_RS01795
-2.6
-1.4
methanogenesis marker 6 protein
compare
MMP
_RS06105
-2.6
-7.8
hydrogenase maturation peptidase HycI
compare
MMP
_RS07875
-2.5
-5.7
hypothetical protein
compare
MMP
_RS07750
-2.5
-3.6
DUF357 domain-containing protein
compare
MMP
_RS02345
-2.5
-3.1
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS08165
-2.5
-2.3
phosphoglycerate dehydrogenase
compare
MMP
_RS03400
-2.5
-1.9
archease
compare
MMP
_RS00985
-2.5
-5.4
CDC48 family AAA ATPase
compare
MMP
_RS08820
-2.4
-4.7
hypothetical protein
compare
MMP
_RS00520
-2.4
-1.5
RNA polymerase Rpb4 family protein
compare
MMP
_RS01220
-2.4
-6.0
hypothetical protein
compare
MMP
_RS06625
-2.4
-1.5
DNA primase
compare
MMP
_RS05815
-2.4
-1.9
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS03390
-2.4
-5.7
malate dehydrogenase
compare
MMP
_RS06670
-2.3
-4.1
glucose-6-phosphate isomerase
compare
MMP
_RS03250
-2.3
-3.9
MJ1244 family protein
compare
MMP
_RS00895
-2.3
-3.4
hypothetical protein
compare
MMP
_RS08335
-2.3
-7.3
NADH-quinone oxidoreductase subunit B family protein
compare
MMP
_RS08645
-2.3
-5.1
UPF0179 family protein
compare
MMP
_RS01325
-2.3
-1.7
dihydroneopterin aldolase family protein
compare
MMP
_RS01915
-2.2
-11.5
DUF354 domain-containing protein
compare
MMP
_RS07710
-2.2
-5.7
cell division protein FtsZ
compare
MMP
_RS01960
-2.2
-0.5
hypothetical protein
compare
MMP
_RS02800
-2.2
-5.2
nucleotidyltransferase domain-containing protein
compare
MMP
_RS04585
-2.2
-9.7
AIR synthase related protein
compare
MMP
_RS06310
-2.2
-4.3
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS07445
-2.2
-5.4
helix-turn-helix domain-containing protein
compare
MMP
_RS01380
-2.2
-2.6
PHP domain-containing protein
compare
MMP
_RS05640
-2.1
-4.6
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS07525
-2.1
-5.6
4Fe-4S binding protein
compare
MMP
_RS05555
-2.1
-1.0
DUF4040 domain-containing protein
compare
MMP
_RS08370
-2.1
-0.6
cation:proton antiporter subunit C
compare
MMP
_RS03095
-2.1
-5.1
diphthine synthase
compare
MMP
_RS01895
-2.1
-11.2
flippase
compare
MMP
_RS02355
-2.1
-2.5
30S ribosomal protein S27ae
compare
MMP
_RS01880
-2.1
-5.7
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS05285
-2.0
-7.3
MMPL family transporter
compare
MMP
_RS07385
-2.0
-1.9
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS01610
-2.0
-2.5
hypothetical protein
compare
MMP
_RS06725
-2.0
-6.5
hypothetical protein
compare
MMP
_RS03205
-2.0
-1.1
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS01500
-2.0
-1.7
CBS domain-containing protein
compare
MMP
_RS07615
-2.0
-4.3
energy-coupling factor ABC transporter permease
compare
MMP
_RS01975
-2.0
-9.7
hypothetical protein
compare
MMP
_RS08360
-1.9
-3.5
hypothetical protein
compare
MMP
_RS07425
-1.9
-4.2
GTP-binding protein
compare
MMP
_RS00735
-1.9
-3.4
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS04875
-1.9
-4.4
energy-converting hydrogenase B subunit P
compare
MMP
_RS07200
-1.9
-4.8
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS01875
-1.9
-5.9
N-acetyltransferase
compare
MMP
_RS07620
-1.9
-3.2
energy-coupling factor ABC transporter substrate-binding protein
compare
MMP
_RS01725
-1.9
-3.3
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS01970
-1.9
-8.0
TIGR04279 domain-containing protein
compare
MMP
_RS07075
-1.9
-2.3
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS01890
-1.8
-2.5
nucleotide sugar dehydrogenase
compare
MMP
_RS01240
-1.8
-1.5
7-cyano-7-deazaguanine synthase QueC
compare
MMP
_RS00295
-1.8
-1.9
gamma carbonic anhydrase family protein
compare
MMP
_RS07720
-1.8
-8.3
4Fe-4S binding protein
compare
MMP
_RS06980
-1.8
-5.3
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS08350
-1.8
-0.8
hypothetical protein
compare
MMP
_RS07605
-1.8
-1.9
diadenylate cyclase
compare
MMP
_RS00315
-1.8
-6.1
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS02885
-1.8
-9.3
molybdopterin biosynthesis protein
compare
MMP
_RS08355
-1.7
-6.2
Na(+)/H(+) antiporter subunit B
compare
Specific Phenotypes
For 1 genes in this experiment