Experiment set4IT045 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with benzoic acid 0.145 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_0208 +0.9 3.6 Response regulator receiver domain compare
Ga0059261_4224 +0.9 2.6 hypothetical protein compare
Ga0059261_2774 +0.8 2.5 Transcription elongation factor compare
Ga0059261_3492 +0.8 5.8 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_1115 +0.8 2.5 Chemotaxis protein; stimulates methylation of MCP proteins compare
Ga0059261_3356 +0.8 1.8 hypothetical protein compare
Ga0059261_3490 +0.7 5.1 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_3581 +0.6 4.4 Alpha/beta hydrolase family compare
Ga0059261_2618 +0.6 2.2 Protein of unknown function (DUF2721) compare
Ga0059261_2076 +0.6 1.1 hypothetical protein compare
Ga0059261_3579 +0.6 3.3 hypothetical protein compare
Ga0059261_0898 +0.6 2.4 Membrane protein implicated in regulation of membrane protease activity compare
Ga0059261_1075 +0.6 1.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_3507 +0.6 5.0 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_2897 +0.5 1.7 hypothetical protein compare
Ga0059261_1316 +0.5 1.2 hypothetical protein compare
Ga0059261_0357 +0.5 2.1 hypothetical protein compare
Ga0059261_1811 +0.5 2.1 ATP:cob(I)alamin adenosyltransferase compare
Ga0059261_1739 +0.5 2.5 Conjugal transfer protein TraD compare
Ga0059261_0757 +0.5 1.7 Predicted transcriptional regulators compare
Ga0059261_0633 +0.4 1.7 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Ga0059261_2913 +0.4 1.6 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_0062 +0.4 2.1 hypothetical protein compare
Ga0059261_1577 +0.4 3.7 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_2188 +0.4 1.2 Uncharacterized conserved protein compare
Ga0059261_3491 +0.4 3.0 hypothetical protein compare
Ga0059261_0244 +0.4 2.2 FOG: CheY-like receiver compare
Ga0059261_0675 +0.4 1.7 hypothetical protein compare
Ga0059261_2830 +0.4 1.6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_2368 +0.4 1.5 Phage baseplate assembly protein W compare
Ga0059261_0864 +0.4 1.3 hypothetical protein compare
Ga0059261_2547 +0.4 0.8 tRNA compare
Ga0059261_1914 +0.4 1.6 Acetyltransferases compare
Ga0059261_1574 +0.4 1.7 Superfamily II DNA and RNA helicases compare
Ga0059261_2721 +0.4 2.2 rare lipoprotein A compare
Ga0059261_0722 +0.4 2.5 L-aminopeptidase/D-esterase compare
Ga0059261_3238 +0.4 1.7 hypothetical protein compare
Ga0059261_3233 +0.3 2.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_3006 +0.3 1.5 hypothetical protein compare
Ga0059261_1259 +0.3 1.6 Ribbon-helix-helix domain compare
Ga0059261_1303 +0.3 1.9 hypothetical protein compare
Ga0059261_1253 +0.3 1.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_3308 +0.3 0.8 Uncharacterized conserved protein compare
Ga0059261_4171 +0.3 1.7 redox-sensitive transcriptional activator SoxR compare
Ga0059261_1939 +0.3 0.7 putative phosphoesterase compare
Ga0059261_2951 +0.3 1.2 Heavy-metal resistance compare
Ga0059261_1847 +0.3 1.5 hypothetical protein compare
Ga0059261_2973 +0.3 1.9 hypothetical protein compare
Ga0059261_1612 +0.3 0.7 hypothetical protein compare
Ga0059261_3759 +0.3 1.2 hypothetical protein compare
Ga0059261_1713 +0.3 2.2 hypothetical protein compare
Ga0059261_1825 +0.3 1.9 hypothetical protein compare
Ga0059261_2587 +0.3 1.3 hypothetical protein compare
Ga0059261_2548 +0.3 1.3 tRNA compare
Ga0059261_1396 +0.3 1.5 EF-hand domain pair compare
Ga0059261_3083 +0.3 1.5 hypothetical protein compare
Ga0059261_3966 +0.3 1.1 Transcriptional regulators compare
Ga0059261_3783 +0.3 1.6 hypothetical protein compare
Ga0059261_3359 +0.3 1.2 Zn-dependent hydrolases, including glyoxylases compare
Ga0059261_2582 +0.3 2.1 hypothetical protein compare
Ga0059261_3321 +0.3 1.4 pyrroline-5-carboxylate reductase compare
Ga0059261_0720 +0.3 1.3 Predicted small integral membrane protein compare
Ga0059261_0889 +0.3 0.7 Cold shock proteins compare
Ga0059261_2992 +0.3 1.4 Biopolymer transport protein compare
Ga0059261_1757 +0.3 1.5 Protein of unknown function (DUF4007) compare
Ga0059261_3884 +0.3 1.5 K+-transporting ATPase, B subunit compare
Ga0059261_4046 +0.3 1.1 Response regulator receiver domain compare
Ga0059261_3022 +0.3 1.3 MerT mercuric transport protein compare
Ga0059261_3800 +0.3 1.3 Cold shock proteins compare
Ga0059261_0405 +0.3 1.9 Uncharacterized conserved protein compare
Ga0059261_1050 +0.3 0.5 hypothetical protein compare
Ga0059261_2448 +0.3 0.8 DNA protecting protein DprA compare
Ga0059261_2086 +0.3 0.6 SAF-like compare
Ga0059261_1016 +0.3 1.2 Cupin domain compare
Ga0059261_0305 +0.3 1.4 bacterioferritin compare
Ga0059261_2477 +0.3 1.6 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Ga0059261_3915 +0.3 1.2 hypothetical protein compare
Ga0059261_4120 +0.3 0.6 Stress responsive A/B Barrel Domain compare
Ga0059261_0832 +0.3 2.3 Predicted permease compare
Ga0059261_3210 +0.3 1.0 Organic radical activating enzymes compare
Ga0059261_1381 +0.3 1.4 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_2022 +0.3 2.6 Peptidase family M49 compare
Ga0059261_0493 +0.3 0.6 hypothetical protein compare
Ga0059261_0488 +0.3 1.3 MerC mercury resistance protein compare
Ga0059261_1578 +0.3 1.8 Rhodanese-like domain compare
Ga0059261_0812 +0.3 1.1 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_2886 +0.3 1.1 electron transfer flavoprotein beta subunit compare
Ga0059261_3833 +0.3 0.9 hypothetical protein compare
Ga0059261_2154 +0.3 1.3 uncharacterized domain 1 compare
Ga0059261_3985 +0.3 1.8 methylmalonyl-CoA epimerase (EC 5.1.99.1) compare
Ga0059261_1957 +0.3 1.4 hypothetical protein compare
Ga0059261_1315 +0.3 1.3 Alpha/beta hydrolase family compare
Ga0059261_4149 +0.3 1.4 psp operon transcriptional activator PspF compare
Ga0059261_2503 +0.3 0.9 Predicted SPOUT methyltransferase compare
Ga0059261_3335 +0.3 1.0 hypothetical protein compare
Ga0059261_4208 +0.3 1.9 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Ga0059261_3675 +0.3 1.2 Methyl-accepting chemotaxis protein compare
Ga0059261_2018 +0.3 1.9 hypothetical protein compare
Ga0059261_3303 +0.3 1.0 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Ga0059261_0161 +0.3 0.9 molybdopterin converting factor, subunit 1, non-archaeal compare
Ga0059261_1844 +0.3 1.6 O-6-methylguanine DNA methyltransferase compare
Ga0059261_4215 +0.3 1.4 Predicted N-formylglutamate amidohydrolase compare
Ga0059261_4192 +0.3 0.9 ATPases involved in chromosome partitioning compare
Ga0059261_1485 +0.3 1.6 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Ga0059261_2842 +0.2 1.7 SnoaL-like domain compare
Ga0059261_0906 +0.2 1.4 Uncharacterized conserved protein compare
Ga0059261_0433 +0.2 0.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_1144 +0.2 1.8 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Ga0059261_3885 +0.2 0.9 K+-transporting ATPase, C subunit compare
Ga0059261_0834 +0.2 1.4 hypothetical protein compare
Ga0059261_0472 +0.2 1.0 Predicted metal-binding protein compare
Ga0059261_3761 +0.2 1.8 hypothetical protein compare
Ga0059261_0671 +0.2 1.0 Uncharacterized conserved protein compare
Ga0059261_3518 +0.2 2.0 RND family efflux transporter, MFP subunit compare
Ga0059261_0205 +0.2 1.4 DNA-3-methyladenine glycosylase I (EC 3.2.2.20) compare
Ga0059261_2496 +0.2 1.3 Hemerythrin HHE cation binding domain compare
Ga0059261_3332 +0.2 1.6 Predicted membrane protein compare
Ga0059261_3316 +0.2 1.3 hypothetical protein compare
Ga0059261_1049 +0.2 1.3 PEP-CTERM protein-sorting domain compare
Ga0059261_0957 +0.2 0.8 Protein of unknown function (DUF2798) compare
Ga0059261_4181 +0.2 1.4 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_3545 +0.2 0.8 hypothetical protein compare
Ga0059261_4084 +0.2 1.7 Glycosyltransferase compare
Ga0059261_4189 +0.2 1.5 hypothetical protein compare
Ga0059261_0655 +0.2 1.5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/Hpt domain/CheW-like domain/Signal transducing histidine kinase, homodimeric domain compare
Ga0059261_1652 +0.2 0.5 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily compare
Ga0059261_0928 +0.2 1.4 Glyoxalase-like domain compare
Ga0059261_2309 +0.2 1.2 transcriptional regulator, LacI family compare
Ga0059261_3947 +0.2 0.8 type II secretion system protein I (GspI) compare
Ga0059261_4146 +0.2 1.6 phage shock protein B compare
Ga0059261_2821 +0.2 1.4 hypothetical protein compare
Ga0059261_3391 +0.2 1.6 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA compare
Ga0059261_3646 +0.2 1.2 Uncharacterized stress protein (general stress protein 26) compare
Ga0059261_2600 +0.2 1.6 Protein of unknown function DUF262 compare
Ga0059261_2978 +0.2 1.1 Transcriptional regulators compare
Ga0059261_3752 +0.2 1.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_3871 +0.2 0.5 formate dehydrogenase family accessory protein FdhD compare
Ga0059261_2562 +0.2 1.3 Uncharacterized conserved small protein compare
Ga0059261_3710 +0.2 1.8 Peptidase family M28 compare
Ga0059261_2966 +0.2 1.3 2-deoxy-D-gluconate 3-dehydrogenase compare
Ga0059261_1934 +0.2 1.1 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Ga0059261_3280 +0.2 0.6 Uncharacterized conserved protein compare
Ga0059261_2675 +0.2 1.6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_3967 +0.2 1.6 hypothetical protein compare
Ga0059261_0199 +0.2 1.1 hypothetical protein compare
Ga0059261_3305 +0.2 1.0 Uncharacterized conserved protein compare
Ga0059261_2436 +0.2 1.1 hypothetical protein compare
Ga0059261_1191 +0.2 1.4 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3522 +0.2 0.9 Micrococcal nuclease (thermonuclease) homologs compare
Ga0059261_3928 +0.2 0.8 Predicted thioesterase compare
Ga0059261_0143 +0.2 1.3 hypothetical protein compare
Ga0059261_0827 +0.2 0.6 hypothetical protein compare
Ga0059261_4016 +0.2 1.6 Predicted transcriptional regulator compare
Ga0059261_1095 +0.2 1.4 Flagellar motor switch protein compare
Ga0059261_0993 +0.2 0.6 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_3831 +0.2 1.3 Putative NADPH-quinone reductase (modulator of drug activity B) compare
Ga0059261_0072 +0.2 1.0 ATPases involved in chromosome partitioning compare
Ga0059261_0039 +0.2 1.2 His Kinase A (phospho-acceptor) domain compare
Ga0059261_0597 +0.2 1.0 hypothetical protein compare
Ga0059261_2055 +0.2 1.1 Predicted flavoprotein compare
Ga0059261_3164 +0.2 1.3 Protein of unknown function (DUF3297) compare
Ga0059261_3271 +0.2 0.4 arsenate reductase (glutaredoxin) compare
Ga0059261_0961 +0.2 1.4 hypothetical protein compare
Ga0059261_3770 +0.2 1.5 Beta-lactamase class A compare
Ga0059261_1064 +0.2 0.8 Uncharacterized conserved protein compare
Ga0059261_0778 +0.2 1.2 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_0450 +0.2 1.0 Putative copper export protein compare
Ga0059261_0229 +0.2 1.1 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Ga0059261_1120 +0.2 1.1 Chemotaxis protein histidine kinase and related kinases compare
Ga0059261_0216 +0.2 1.3 transcription elongation factor GreB compare
Ga0059261_0654 +0.2 1.0 Chemotaxis signal transduction protein compare
Ga0059261_2885 +0.2 1.1 Electron transfer flavoprotein, alpha subunit compare
Ga0059261_2361 +0.2 1.0 Staphylococcal nuclease homologue compare
Ga0059261_1320 +0.2 1.5 ABC-type antimicrobial peptide transport system, permease component compare
Ga0059261_0301 +0.2 1.4 hypothetical protein compare
Ga0059261_0024 +0.2 1.1 Predicted membrane protein compare
Ga0059261_3206 +0.2 1.1 ornithine carbamoyltransferase compare
Ga0059261_0926 +0.2 1.0 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Ga0059261_1838 +0.2 1.2 hypothetical protein compare
Ga0059261_2234 +0.2 1.2 Glycerol-3-phosphate dehydrogenase compare
Ga0059261_1224 +0.2 1.4 transcriptional regulator compare
Ga0059261_1433 +0.2 1.7 Predicted aminopeptidases compare
Ga0059261_3243 +0.2 1.4 Flp pilus assembly protein, secretin CpaC compare
Ga0059261_3799 +0.2 0.8 hypothetical protein compare
Ga0059261_3991 +0.2 1.6 Predicted hydrolase of the alpha/beta superfamily compare
Ga0059261_3168 +0.2 1.1 peroxiredoxin, OsmC subfamily compare
Ga0059261_3992 +0.2 0.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1758 +0.2 1.3 hypothetical protein compare
Ga0059261_0871 +0.2 1.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_1256 +0.2 1.3 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Ga0059261_2097 +0.2 0.8 Rod binding protein compare
Ga0059261_0749 +0.2 1.1 Membrane transporters of cations and cationic drugs compare
Ga0059261_0410 +0.2 1.3 Antirestriction protein compare
Ga0059261_1117 +0.2 1.4 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain compare
Ga0059261_0059 +0.2 0.5 Stress-induced morphogen (activity unknown) compare
Ga0059261_1082 +0.2 1.1 Chemotaxis signal transduction protein compare
Ga0059261_0612 +0.2 0.8 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3577 +0.2 1.0 Uncharacterized conserved protein compare
Ga0059261_1387 +0.2 1.2 Rhodanese-related sulfurtransferase compare
Ga0059261_1837 +0.2 0.6 Staphylococcal nuclease homologue compare


Specific Phenotypes

None in this experiment

For Sphingomonas koreensis DSMZ 15582 in stress experiments

For stress benzoic acid across organisms