Experiment set4IT039 for Rhodospirillum rubrum S1H

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L-Malic Acid carbon source with ammonium chloride; high light

200 most important genes:

  gene name fitness t score description  
Rru_A3594 -6.8 -3.6 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A3558 -6.2 -5.4 Protein of unknown function UPF0005 (NCBI) compare
Rru_A3425 -6.1 -8.1 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A0469 -6.0 -22.4 Ketol-acid reductoisomerase (NCBI) compare
Rru_A1896 -5.9 -9.9 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A2772 -5.8 -3.4 ATP phosphoribosyltransferase (NCBI) compare
Rru_A1928 -5.8 -20.1 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A3751 -5.7 -17.8 Argininosuccinate synthase (NCBI) compare
Rru_A1897 -5.6 -9.4 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A2886 -5.6 -34.1 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A3162 -5.5 -22.8 Prephenate dehydratase (NCBI) compare
Rru_A0432 -5.5 -5.9 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A1021 -5.5 -11.1 Sigma 32 (RpoH) (NCBI) compare
Rru_A2885 -5.4 -25.3 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A1530 -5.4 -29.9 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A3277 -5.4 -7.3 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1105 -5.3 -8.8 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A1883 -5.1 -4.6 Magnesium and cobalt transport protein CorA (NCBI) compare
Rru_A3596 -5.0 -7.6 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A2507 -5.0 -24.9 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A1191 -5.0 -14.6 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A1675 -4.9 -19.4 Cytochrome c assembly protein (NCBI) compare
Rru_A1189 -4.9 -14.6 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3191 -4.7 -21.7 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1895 -4.7 -1.8 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A3266 -4.7 -18.7 Homoserine O-acetyltransferase (NCBI) compare
Rru_A1827 -4.7 -16.1 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A3264 -4.7 -11.6 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A1798 -4.6 -14.4 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A2771 -4.6 -7.1 Histidinol dehydrogenase (NCBI) compare
Rru_A3428 -4.6 -13.6 Tryptophan synthase (NCBI) compare
Rru_A3267 -4.5 -10.0 Methionine biosynthesis MetW (NCBI) compare
Rru_A3427 -4.5 -18.6 Tryptophan synthase, beta chain (NCBI) compare
Rru_A1620 -4.5 -3.9 hypothetical protein (NCBI) compare
Rru_A1190 -4.5 -1.7 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A0467 -4.4 -16.7 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A1593 -4.4 -14.0 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A3214 -4.3 -13.1 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A2936 -4.3 -9.1 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1786 -4.3 -18.2 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1854 -4.2 -8.4 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A3571 -4.2 -13.8 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A0574 -4.2 -5.9 Carboxylyase-related protein (NCBI) compare
Rru_A0963 -4.2 -6.4 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A0514 -4.0 -8.1 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A3202 -3.9 -11.8 DNA topoisomerase (NCBI) compare
Rru_A1434 -3.9 -20.8 Quinolinate synthetase A (NCBI) compare
Rru_A0397 -3.9 -6.0 Argininosuccinate lyase (NCBI) compare
Rru_A3276 -3.8 -6.1 Ornithine carbamoyltransferase (NCBI) compare
Rru_A3548 -3.6 -19.2 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A0644 -3.6 -2.8 hypothetical protein (NCBI) compare
Rru_A3380 -3.6 -3.8 hypothetical protein (NCBI) compare
Rru_A1239 -3.6 -3.0 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0468 -3.5 -6.6 Acetolactate synthase, small subunit (NCBI) compare
Rru_A1432 -3.5 -15.4 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A2847 -3.4 -3.1 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A1837 -3.4 -8.4 Porphobilinogen synthase (NCBI) compare
Rru_A2167 -3.4 -6.2 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A0058 -3.2 -1.4 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A0770 -3.2 -12.8 Peptidase M23B (NCBI) compare
Rru_A1695 -3.1 -8.3 Protein of unknown function DUF411 (NCBI) compare
Rru_A0637 -3.0 -3.5 hypothetical protein (NCBI) compare
Rru_A0032 -3.0 -8.8 TPR repeat (NCBI) compare
Rru_A2987 -2.9 -7.3 hypothetical protein (NCBI) compare
Rru_A1436 -2.9 -8.6 Histidine Kinase (NCBI) compare
Rru_A2975 -2.9 -17.9 Photosynthetic reaction centre protein L subunit (NCBI) compare
Rru_A0486 -2.9 -13.6 von Willebrand factor, type A (NCBI) compare
Rru_A3699 -2.9 -18.1 Acriflavin resistance protein (NCBI) compare
Rru_A2512 -2.8 -5.4 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A1366 -2.8 -21.2 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A2988 -2.8 -7.3 Precorrin-6X reductase (NCBI) compare
Rru_A0620 -2.7 -13.8 Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein (NCBI) compare
Rru_A2497 -2.7 -8.0 Peptide chain release factor 3 (NCBI) compare
Rru_A1437 -2.7 -10.5 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A2974 -2.7 -15.5 Photosynthetic reaction centre M subunit (NCBI) compare
Rru_A2980 -2.7 -12.8 Chlorophyllide reductase iron protein subunit X (NCBI) compare
Rru_A0485 -2.6 -9.7 Magnesium chelatase ATPase subunit I (NCBI) compare
Rru_A3165 -2.6 -4.6 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A3382 -2.6 -11.2 Cobalamin biosynthesis protein CbiB (NCBI) compare
Rru_A0622 -2.6 -12.4 Light-independent protochlorophyllide reductase, B subunit (NCBI) compare
Rru_A2992 -2.6 -4.3 Precorrin-6Y C5,15-methyltransferase (decarboxylating) (NCBI) compare
Rru_A2981 -2.6 -9.6 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide (NCBI) compare
Rru_A0613 -2.6 -6.8 Bacteriochlorophyll 4-vinyl reductase (NCBI) compare
Rru_B0050 -2.5 -1.6 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A3424 -2.5 -1.8 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A1433 -2.5 -9.0 L-aspartate oxidase (NCBI) compare
Rru_A2986 -2.5 -8.3 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) compare
Rru_A0493 -2.5 -16.0 Phytoene desaturase (NCBI) compare
Rru_A0621 -2.5 -18.4 Magnesium-chelatase, subunit H (NCBI) compare
Rru_A2989 -2.5 -5.9 Precorrin-3B C17-methyltransferase region (NCBI) compare
Rru_A0618 -2.5 -12.3 PUCC protein (NCBI) compare
Rru_A0616 -2.5 -12.5 photosynthetic complex assembly protein (NCBI) compare
Rru_A0617 -2.4 -7.1 Photosynthetic reaction center, H-chain (NCBI) compare
Rru_A1849 -2.4 -3.2 Recombination protein O, RecO (NCBI) compare
Rru_A1048 -2.4 -2.9 Protein of unknown function DUF465 (NCBI) compare
Rru_A0624 -2.4 -14.9 2-vinyl bacteriochlorophyllide hydratase (NCBI) compare
Rru_A0627 -2.4 -11.1 Bacteriochlorophyll/chlorophyll synthetase (NCBI) compare
Rru_A0615 -2.4 -4.1 photosynthetic complex assembly protein (NCBI) compare
Rru_A0614 -2.4 -9.4 hypothetical protein (NCBI) compare
Rru_A3642 -2.4 -2.5 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A2524 -2.4 -13.0 Peptidase U32 (NCBI) compare
Rru_A0619 -2.3 -4.0 Magnesium protoporphyrin O-methyltransferase (NCBI) compare
Rru_A0394 -2.3 -2.3 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A3168 -2.3 -12.7 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3549 -2.3 -9.6 Cobyric acid synthase CobQ (NCBI) compare
Rru_A3359 -2.3 -7.3 Cobyrinic acid a,c-diamide synthase CbiA (NCBI) compare
Rru_A0494 -2.3 -10.5 Squalene/phytoene synthase (NCBI) compare
Rru_A0752 -2.2 -3.6 hypothetical protein (NCBI) compare
Rru_A2525 -2.2 -12.1 Peptidase U32 (NCBI) compare
Rru_A3700 -2.2 -7.8 Secretion protein HlyD (NCBI) compare
Rru_A0404 -2.2 -16.3 Amidophosphoribosyl transferase (NCBI) compare
Rru_A0596 -2.2 -2.1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A0181 -2.2 -7.3 hypothetical protein (NCBI) compare
Rru_A0556 -2.2 -11.9 Formyltetrahydrofolate deformylase (NCBI) compare
Rru_A3010 -2.1 -8.0 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3190 -2.1 -1.8 Aspartate carbamoyltransferase (NCBI) compare
Rru_A0212 -2.1 -0.9 hypothetical protein (NCBI) compare
Rru_A2990 -2.1 -10.8 precorrin-2 C20-methyltransferase (NCBI) compare
Rru_A2979 -2.1 -8.2 Chlorophyllide reductase subunit Y (NCBI) compare
Rru_A1276 -2.1 -17.0 ATP-cone (NCBI) compare
Rru_A1274 -2.0 -10.3 Radical SAM (NCBI) compare
Rru_A2100 -2.0 -5.4 Protein of unknown function DUF81 (NCBI) compare
Rru_A3169 -2.0 -10.4 ABC transporter component (NCBI) compare
Rru_A1435 -2.0 -5.3 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A1677 -2.0 -5.3 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A2978 -2.0 -9.5 Chlorophyllide reductase subunit Z (NCBI) compare
Rru_A3550 -2.0 -8.3 Cobyric acid synthase CobQ (NCBI) compare
Rru_A1718 -2.0 -16.8 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) compare
Rru_A1019 -2.0 -4.7 FAD dependent oxidoreductase (NCBI) compare
Rru_A1527 -1.9 -5.8 ABC transporter component (NCBI) compare
Rru_A0010 -1.9 -3.3 Sigma-54 (RpoN) (NCBI) compare
Rru_A1309 -1.9 -10.5 acetoacetyl-CoA reductase (NCBI) compare
Rru_A1275 -1.9 -3.6 hypothetical protein (NCBI) compare
Rru_A2983 -1.9 -1.8 Polyprenyl synthetase (NCBI) compare
Rru_A3167 -1.9 -10.0 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A0291 -1.9 -4.2 hypothetical protein (NCBI) compare
Rru_A3227 -1.9 -11.0 conserved hypothetical protein, potential methyltransferase (NCBI) compare
Rru_A1111 -1.8 -9.3 Pseudouridine synthase, RluD (NCBI) compare
Rru_A3384 -1.8 -5.3 Precorrin-4 C11-methyltransferase region (NCBI) compare
Rru_A3166 -1.8 -11.0 extracellular solute-binding protein, family 5 (NCBI) compare
Rru_A2411 -1.8 -9.7 Aminotransferase, class I and II (NCBI) compare
Rru_A2182 -1.8 -4.9 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A0454 -1.8 -2.4 Leucyl aminopeptidase (NCBI) compare
Rru_A0625 -1.8 -2.8 hypothetical protein (NCBI) compare
Rru_A2161 -1.8 -16.1 Polyphosphate kinase (NCBI) compare
Rru_A0670 -1.7 -2.8 Cobalbumin biosynthesis enzyme (NCBI) compare
Rru_A2404 -1.7 -11.2 Phosphoribulokinase (NCBI) compare
Rru_A0629 -1.7 -9.3 Geranylgeranyl reductase (NCBI) compare
Rru_A1829 -1.7 -13.7 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A3547 -1.7 -4.3 hypothetical protein (NCBI) compare
Rru_A1696 -1.7 -3.6 permease (NCBI) compare
Rru_A1691 -1.7 -8.8 Spermine synthase (NCBI) compare
Rru_A2887 -1.7 -2.0 GreA/GreB family elongation factor (NCBI) compare
Rru_A0683 -1.7 -0.6 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1310 -1.7 -6.6 Acetyl-CoA C-acyltransferase (NCBI) compare
Rru_A2181 -1.6 -10.4 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A2400 -1.6 -10.8 Ribulose-bisphosphate carboxylase, form II (NCBI) compare
Rru_A0569 -1.6 -6.6 Chorismate mutase (NCBI) compare
Rru_A1572 -1.6 -3.4 Glyoxalase/bleomycin resistance protein/dioxygenase (NCBI) compare
Rru_A0369 -1.6 -6.4 ATPase associated with various cellular activities, AAA_3 (NCBI) compare
Rru_A0671 -1.6 -5.1 cobalamin synthesis CobW protein (NCBI) compare
Rru_A2115 -1.5 -6.1 Phosphoglucomutase/phosphomannomutase (NCBI) compare
Rru_A0412 -1.5 -2.9 hypothetical protein (NCBI) compare
Rru_A2403 -1.5 -10.7 Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) compare
Rru_A0652 -1.5 -3.1 Pseudouridine synthase, Rsu (NCBI) compare
Rru_A2549 -1.5 -9.5 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A2421 -1.5 -3.7 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2244 -1.5 -9.9 Glycogen/starch/alpha-glucan phosphorylase (NCBI) compare
Rru_A3533 -1.5 -6.6 hypothetical protein (NCBI) compare
Rru_A2952 -1.5 -3.3 Methyltransferase small (NCBI) compare
Rru_A2970 -1.4 -8.1 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase (NCBI) compare
Rru_A2510 -1.4 -1.5 hypothetical protein (NCBI) compare
Rru_A2370 -1.4 -0.9 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A1327 -1.4 -2.0 hypothetical protein (NCBI) compare
Rru_A3139 -1.4 -6.6 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A3770 -1.4 -6.5 tRNA-i(6)A37 modification enzyme MiaB (NCBI) compare
Rru_A3766 -1.4 -6.2 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A1015 -1.4 -3.8 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3739 -1.3 -5.6 hypothetical protein (NCBI) compare
Rru_A0484 -1.3 -5.1 hypothetical protein (NCBI) compare
Rru_A3621 -1.3 -2.9 Methylated-DNA-(protein)-cysteine S-methyltransferase (NCBI) compare
Rru_A2651 -1.3 -5.5 Aminotransferase, class I and II (NCBI) compare
Rru_A1179 -1.3 -1.4 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1529 -1.3 -3.5 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A1855 -1.3 -3.8 hypothetical protein (NCBI) compare
Rru_A1308 -1.2 -8.0 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A2183 -1.2 -5.3 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A3322 -1.2 -2.8 Transcriptional Regulator, Crp/Fnr family (NCBI) compare
Rru_A1865 -1.2 -6.5 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A3773 -1.2 -1.6 CBS domain protein (NCBI) compare
Rru_A2770 -1.2 -1.8 Uncharacterized conserved protein UCP032146 (NCBI) compare
Rru_A1804 -1.2 -6.2 N-acetyltransferase (NCBI) compare
Rru_A1047 -1.2 -6.4 6-phosphofructokinase (NCBI) compare
Rru_A3701 -1.2 -4.4 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A1339 -1.2 -8.1 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3788 -1.2 -4.8 Ferric uptake regulator (FUR) family (NCBI) compare
Rru_A1884 -1.2 -1.4 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) compare
Rru_A3285 -1.2 -2.4 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A1085 -1.2 -3.7 Metallophosphoesterase (NCBI) compare
Rru_A2363 -1.2 -6.7 Endonuclease/exonuclease/phosphatase (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For anaerboic nitrogen source Ammonium chloride in Rhodospirillum rubrum S1H

For anaerboic nitrogen source Ammonium chloride across organisms