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Experiment set4IT036 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS03315
-3.8
-2.5
ferrous iron transport protein A
compare
MMP
_RS03035
-3.2
-7.0
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS07845
-3.0
-3.7
LL-diaminopimelate aminotransferase
compare
MMP
_RS08210
-2.8
-3.1
phosphatidylglycerophosphatase A
compare
MMP
_RS03435
-2.8
-2.8
ketol-acid reductoisomerase
compare
MMP
_RS02010
-2.6
-14.1
PHP domain-containing protein
compare
MMP
_RS06315
-2.5
-1.8
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS07730
-2.5
-2.9
pyruvate synthase subunit beta
compare
MMP
_RS04605
-2.5
-8.4
cobalt ECF transporter T component CbiQ
compare
MMP
_RS05500
-2.5
-11.7
2-isopropylmalate synthase
compare
MMP
_RS01545
-2.5
-1.8
CBS domain-containing protein
compare
MMP
_RS01175
-2.4
-5.4
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS01005
-2.4
-2.2
riboflavin synthase
compare
MMP
_RS07635
-2.3
-8.0
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS07345
-2.3
-7.9
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS05515
-2.2
-7.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS04615
-2.2
-6.1
PDGLE domain-containing protein
compare
MMP
_RS04620
-2.2
-13.2
cobalt transporter CbiM
compare
MMP
_RS01830
-2.2
-2.8
tRNA-Val
compare
MMP
_RS03015
-2.2
-11.9
GTP 3' 8-cyclase MoaA
compare
MMP
_RS03450
-2.2
-3.6
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS07005
-2.1
-1.1
4Fe-4S binding protein
compare
MMP
_RS06350
-2.1
-8.0
HesA/MoeB/ThiF family protein
compare
MMP
_RS06270
-2.1
-7.2
TIGR00300 family protein
compare
MMP
_RS04215
-2.1
-12.4
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS05265
-2.1
-3.2
2-isopropylmalate synthase
compare
MMP
_RS07630
-2.0
-1.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS03600
-2.0
-2.5
triose-phosphate isomerase
compare
MMP
_RS07735
-2.0
-1.3
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01455
-2.0
-9.7
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS08745
-2.0
-7.2
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS07380
-2.0
-3.3
transcription elongation factor Spt5
compare
MMP
_RS02195
-2.0
-5.1
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS01225
-1.9
-4.5
DUF5379 domain-containing protein
compare
MMP
_RS05425
-1.9
-7.0
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS06630
-1.9
-1.2
UPF0058 family protein
compare
MMP
_RS01265
-1.9
-4.0
hypothetical protein
compare
MMP
_RS02280
-1.9
-1.3
DUF211 domain-containing protein
compare
MMP
_RS04500
-1.9
-14.0
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS05060
-1.9
-13.0
AAA family ATPase
compare
MMP
_RS01020
-1.9
-1.5
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS06730
-1.9
-2.2
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS02355
-1.9
-4.1
30S ribosomal protein S27ae
compare
MMP
_RS06355
-1.9
-3.0
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS06895
-1.8
-2.8
selenocysteine-specific translation elongation factor
compare
MMP
_RS05930
-1.8
-2.5
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS07575
-1.8
-5.7
RNA ligase partner protein
compare
MMP
_RS01755
-1.8
-1.7
DUF2097 domain-containing protein
compare
MMP
_RS01610
-1.8
-4.9
hypothetical protein
compare
MMP
_RS07555
-1.8
-1.1
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS05090
-1.8
-10.6
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS05095
-1.8
-8.1
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS02240
-1.7
-3.5
methanogenesis marker 7 protein
compare
MMP
_RS05100
-1.7
-12.8
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS03400
-1.7
-3.1
archease
compare
MMP
_RS06285
-1.7
-3.4
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS00110
-1.7
-2.5
hypothetical protein
compare
MMP
_RS02135
-1.7
-3.7
DUF5612 domain-containing protein
compare
MMP
_RS05075
-1.7
-13.4
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS09020
-1.7
-1.7
hypothetical protein
compare
MMP
_RS06215
-1.6
-3.7
30S ribosomal protein S6e
compare
MMP
_RS07545
-1.6
-1.4
HTH domain-containing protein
compare
MMP
_RS08165
-1.6
-2.5
phosphoglycerate dehydrogenase
compare
MMP
_RS08790
-1.6
-3.0
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS06370
-1.6
-5.9
biotin synthase BioB
compare
MMP
_RS06375
-1.6
-8.9
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS05070
-1.6
-8.2
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS02235
-1.6
-9.6
CBS domain-containing protein
compare
MMP
_RS05080
-1.6
-11.9
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS03640
-1.5
-3.4
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08095
-1.5
-7.4
dethiobiotin synthase
compare
MMP
_RS07955
-1.5
-4.4
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS07185
-1.5
-10.4
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS08105
-1.5
-8.7
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS06105
-1.5
-9.2
hydrogenase maturation peptidase HycI
compare
MMP
_RS07645
-1.5
-6.3
aldehyde dehydrogenase family protein
compare
MMP
_RS03700
-1.5
-8.3
sodium:proton antiporter
compare
MMP
_RS01220
-1.5
-6.3
hypothetical protein
compare
MMP
_RS05085
-1.5
-7.9
AAA family ATPase
compare
MMP
_RS04790
-1.5
-9.6
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS01795
-1.5
-2.2
methanogenesis marker 6 protein
compare
MMP
_RS08240
-1.5
-7.4
methanogenesis marker 16 metalloprotein
compare
MMP
_RS01955
-1.5
-4.0
hypothetical protein
compare
MMP
_RS06700
-1.5
-9.7
hypothetical protein
compare
MMP
_RS00685
-1.4
-4.8
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS06340
-1.4
-6.8
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS00320
-1.4
-2.5
class I SAM-dependent methyltransferase
compare
MMP
_RS07600
-1.4
-2.9
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06475
-1.4
-5.4
FAD-dependent oxidoreductase
compare
MMP
_RS06400
-1.4
-2.2
4Fe-4S binding protein
compare
MMP
_RS07755
-1.4
-1.5
DUF555 domain-containing protein
compare
MMP
_RS05550
-1.4
-0.8
cation:proton antiporter
compare
MMP
_RS06120
-1.4
-2.5
UPF0147 family protein
compare
MMP
_RS05815
-1.4
-2.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS00810
-1.4
-6.2
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS02885
-1.4
-11.1
molybdopterin biosynthesis protein
compare
MMP
_RS08720
-1.4
-1.4
4Fe-4S binding protein
compare
MMP
_RS02900
-1.4
-0.9
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS03145
-1.4
-4.3
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS06295
-1.4
-6.1
methanogenesis marker 14 protein
compare
MMP
_RS05950
-1.4
-7.8
nickel-dependent hydrogenase large subunit
compare
MMP
_RS03390
-1.4
-5.2
malate dehydrogenase
compare
MMP
_RS01385
-1.4
-0.8
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS05555
-1.4
-1.7
DUF4040 domain-containing protein
compare
MMP
_RS08330
-1.4
-5.8
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS05055
-1.3
-10.2
DUF166 domain-containing protein
compare
MMP
_RS04775
-1.3
-3.8
adenosylhomocysteinase
compare
MMP
_RS03475
-1.3
-0.8
hypothetical protein
compare
MMP
_RS07195
-1.3
-8.2
M20 family metallo-hydrolase
compare
MMP
_RS08100
-1.3
-6.7
8-amino-7-oxononanoate synthase
compare
MMP
_RS05845
-1.3
-1.9
tRNA-intron lyase
compare
MMP
_RS00735
-1.3
-4.4
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS05540
-1.3
-3.3
hypothetical protein
compare
MMP
_RS00750
-1.3
-2.8
fumarate hydratase
compare
MMP
_RS02875
-1.3
-8.0
chorismate pyruvate-lyase family protein
compare
MMP
_RS04850
-1.3
-10.4
UPF0254 family protein
compare
MMP
_RS00725
-1.3
-6.7
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS07445
-1.3
-5.3
helix-turn-helix domain-containing protein
compare
MMP
_RS00985
-1.3
-5.8
CDC48 family AAA ATPase
compare
MMP
_RS08715
-1.3
-1.6
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS08320
-1.3
-4.7
molybdopterin molybdotransferase MoeA
compare
MMP
_RS08370
-1.3
-0.8
cation:proton antiporter subunit C
compare
MMP
_RS08635
-1.2
-1.9
UbiA family prenyltransferase
compare
MMP
_RS03140
-1.2
-9.3
hypothetical protein
compare
MMP
_RS06395
-1.2
-2.9
ThiF family adenylyltransferase
compare
MMP
_RS07525
-1.2
-6.5
4Fe-4S binding protein
compare
MMP
_RS06685
-1.2
-7.5
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS07750
-1.2
-4.5
DUF357 domain-containing protein
compare
MMP
_RS06680
-1.2
-6.5
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06885
-1.2
-2.8
50S ribosome-binding GTPase
compare
MMP
_RS07700
-1.2
-8.0
DUF1188 domain-containing protein
compare
MMP
_RS01700
-1.2
-1.1
dihydroxy-acid dehydratase
compare
MMP
_RS03025
-1.2
-3.9
molybdenum cofactor guanylyltransferase
compare
MMP
_RS03420
-1.2
-4.3
acetolactate synthase small subunit
compare
MMP
_RS07355
-1.2
-1.2
transcription factor S
compare
MMP
_RS08355
-1.1
-4.6
Na(+)/H(+) antiporter subunit B
compare
MMP
_RS07710
-1.1
-6.0
cell division protein FtsZ
compare
MMP
_RS02800
-1.1
-3.6
nucleotidyltransferase domain-containing protein
compare
MMP
_RS01800
-1.1
-3.8
TIGR00303 family protein
compare
MMP
_RS00895
-1.1
-3.8
hypothetical protein
compare
MMP
_RS07200
-1.1
-5.6
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS08345
-1.1
-8.0
4Fe-4S binding protein
compare
MMP
_RS04710
-1.1
-1.6
hypothetical protein
compare
MMP
_RS03095
-1.1
-4.1
diphthine synthase
compare
MMP
_RS02470
-1.1
-1.9
helix-turn-helix transcriptional regulator
compare
MMP
_RS01720
-1.1
-1.3
replication factor C large subunit
compare
MMP
_RS01840
-1.1
-6.3
TIGR00289 family protein
compare
MMP
_RS06705
-1.1
-4.6
formate/nitrite transporter family protein
compare
MMP
_RS07540
-1.1
-3.1
CBS domain-containing protein
compare
MMP
_RS01500
-1.1
-1.5
CBS domain-containing protein
compare
MMP
_RS04875
-1.1
-3.6
energy-converting hydrogenase B subunit P
compare
MMP
_RS07720
-1.0
-8.0
4Fe-4S binding protein
compare
MMP
_RS07695
-1.0
-5.6
DUF3236 domain-containing protein
compare
MMP
_RS04890
-1.0
-0.9
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS04585
-1.0
-6.3
AIR synthase related protein
compare
MMP
_RS09055
-1.0
-1.0
CAP domain-containing protein
compare
MMP
_RS00300
-1.0
-0.7
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS05925
-1.0
-3.0
small nuclear ribonucleoprotein
compare
MMP
_RS00130
-1.0
-1.3
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS05065
-1.0
-2.7
CooT family nickel-binding protein
compare
MMP
_RS03250
-1.0
-4.2
MJ1244 family protein
compare
MMP
_RS06980
-1.0
-5.8
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS08595
-1.0
-1.0
flagellar protein C
compare
MMP
_RS06020
-1.0
-3.7
archaeoflavoprotein AfpA
compare
MMP
_RS01380
-1.0
-4.1
PHP domain-containing protein
compare
MMP
_RS08360
-1.0
-2.2
hypothetical protein
compare
MMP
_RS06345
-1.0
-5.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS01325
-1.0
-2.2
dihydroneopterin aldolase family protein
compare
MMP
_RS05430
-1.0
-3.9
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS08645
-1.0
-3.9
UPF0179 family protein
compare
MMP
_RS08820
-1.0
-2.6
hypothetical protein
compare
MMP
_RS00295
-1.0
-2.3
gamma carbonic anhydrase family protein
compare
MMP
_RS04785
-1.0
-6.4
hypothetical protein
compare
MMP
_RS08365
-0.9
-2.9
energy conserving hydrogenase EhbF
compare
MMP
_RS07385
-0.9
-1.9
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS03445
-0.9
-0.9
methanogenesis marker 17 protein
compare
MMP
_RS06130
-0.9
-2.9
peptidylprolyl isomerase
compare
MMP
_RS08760
-0.9
-2.1
hypothetical protein
compare
MMP
_RS07425
-0.9
-4.0
GTP-binding protein
compare
MMP
_RS04685
-0.9
-2.2
DUF126 domain-containing protein
compare
MMP
_RS01240
-0.9
-1.9
7-cyano-7-deazaguanine synthase QueC
compare
MMP
_RS03465
-0.9
-1.3
adenine phosphoribosyltransferase
compare
MMP
_RS00115
-0.9
-6.9
radical SAM protein
compare
MMP
_RS06230
-0.9
-2.8
helix-turn-helix domain-containing protein
compare
MMP
_RS07580
-0.9
-2.3
DUF356 domain-containing protein
compare
MMP
_RS06930
-0.9
-6.2
MBL fold metallo-hydrolase
compare
MMP
_RS06720
-0.9
-3.8
response regulator transcription factor
compare
MMP
_RS06865
-0.9
-1.8
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS00730
-0.9
-3.0
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS08335
-0.8
-4.1
NADH-quinone oxidoreductase subunit B family protein
compare
MMP
_RS01075
-0.8
-1.7
hypothetical protein
compare
MMP
_RS00520
-0.8
-1.2
RNA polymerase Rpb4 family protein
compare
MMP
_RS04780
-0.8
-2.2
ribonuclease P
compare
MMP
_RS03155
-0.8
-3.6
precorrin-6A reductase
compare
MMP
_RS02245
-0.8
-2.0
hypothetical protein
compare
MMP
_RS00515
-0.8
-0.7
DUF655 domain-containing protein
compare
MMP
_RS02165
-0.8
-3.8
tRNA-dihydrouridine synthase
compare
MMP
_RS03585
-0.8
-2.5
Hsp20/alpha crystallin family protein
compare
MMP
_RS06485
-0.8
-0.9
zinc ribbon domain-containing protein
compare
MMP
_RS05245
-0.8
-4.3
archaeosine biosynthesis radical SAM protein RaSEA
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments