Experiment set4IT035 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07005		-3.3	-0.9	4Fe-4S binding protein
MMP_RS07845		-2.8	-3.3	LL-diaminopimelate aminotransferase
MMP_RS05550		-2.4	-0.8	cation:proton antiporter
MMP_RS05425		-2.2	-6.4	monovalent cation/H+ antiporter complex subunit F
MMP_RS03315		-2.1	-1.6	ferrous iron transport protein A
MMP_RS01005		-2.1	-1.8	riboflavin synthase
MMP_RS06400		-2.0	-2.1	4Fe-4S binding protein
MMP_RS03035		-2.0	-4.2	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS09020		-1.9	-1.6	hypothetical protein
MMP_RS03015		-1.9	-8.7	GTP 3' 8-cyclase MoaA
MMP_RS04620		-1.9	-11.7	cobalt transporter CbiM
MMP_RS06355		-1.9	-2.8	molybdenum cofactor biosynthesis protein MoaE
MMP_RS01455		-1.8	-7.1	nickel pincer cofactor biosynthesis protein LarC
MMP_RS03450		-1.8	-2.6	glycine synthesis protein GlyXS (from data)
MMP_RS01225		-1.8	-5.4	DUF5379 domain-containing protein
MMP_RS05500		-1.8	-8.7	2-isopropylmalate synthase
MMP_RS05515		-1.8	-6.9	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS04605		-1.7	-4.1	cobalt ECF transporter T component CbiQ
MMP_RS01830		-1.7	-1.8	tRNA-Val
MMP_RS03435		-1.6	-1.7	ketol-acid reductoisomerase
MMP_RS02010		-1.6	-7.6	PHP domain-containing protein
MMP_RS08745		-1.6	-6.7	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS00130		-1.6	-1.4	nickel-responsive transcriptional regulator NikR
MMP_RS08725		-1.6	-2.5	Ni/Fe hydrogenase subunit alpha
MMP_RS03445		-1.6	-1.0	methanogenesis marker 17 protein
MMP_RS04615		-1.5	-4.2	PDGLE domain-containing protein
MMP_RS05060		-1.5	-10.3	AAA family ATPase
MMP_RS01265		-1.5	-2.2	hypothetical protein
MMP_RS03640		-1.5	-3.5	archaeal proteasome endopeptidase complex subunit beta
MMP_RS05095		-1.4	-7.3	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS06350		-1.4	-6.5	HesA/MoeB/ThiF family protein
MMP_RS02235		-1.4	-7.1	CBS domain-containing protein
MMP_RS07345		-1.4	-6.9	glycine synthesis protein GlyXL (from data)
MMP_RS08715		-1.4	-2.1	formylmethanofuran dehydrogenase subunit B
MMP_RS01175		-1.4	-3.8	triphosphoribosyl-dephospho-CoA synthase
MMP_RS08330		-1.4	-5.0	NADH-quinone oxidoreductase subunit H
MMP_RS07635		-1.4	-5.4	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS04500		-1.4	-11.0	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS00735		-1.4	-4.3	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS02135		-1.4	-3.8	DUF5612 domain-containing protein
MMP_RS08095		-1.3	-6.2	dethiobiotin synthase
MMP_RS02240		-1.3	-3.3	methanogenesis marker 7 protein
MMP_RS01545		-1.3	-1.1	CBS domain-containing protein
MMP_RS08760		-1.3	-2.9	hypothetical protein
MMP_RS02195		-1.3	-3.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS07575		-1.3	-4.2	RNA ligase partner protein
MMP_RS05100		-1.3	-10.0	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS05080		-1.3	-9.8	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS03475		-1.3	-0.6	hypothetical protein
MMP_RS00685		-1.3	-3.3	2-phospho-L-lactate guanylyltransferase
MMP_RS03600		-1.3	-2.0	triose-phosphate isomerase
MMP_RS06340		-1.3	-5.0	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06105		-1.3	-6.1	hydrogenase maturation peptidase HycI
MMP_RS08105		-1.3	-5.9	6-carboxyhexanoate--CoA ligase
MMP_RS06925		-1.3	-2.0	ribonuclease VapC4
MMP_RS05075		-1.2	-10.1	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMP_RS06705		-1.2	-3.5	formate/nitrite transporter family protein
MMP_RS08210		-1.2	-1.8	phosphatidylglycerophosphatase A
MMP_RS07630		-1.2	-1.1	ATP-binding cassette domain-containing protein
MMP_RS06270		-1.2	-6.3	TIGR00300 family protein
MMP_RS04790		-1.2	-7.8	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS02885		-1.2	-9.1	molybdopterin biosynthesis protein
MMP_RS06295		-1.2	-4.6	methanogenesis marker 14 protein
MMP_RS08720		-1.2	-1.2	4Fe-4S binding protein
MMP_RS01220		-1.2	-4.9	hypothetical protein
MMP_RS02355		-1.2	-2.4	30S ribosomal protein S27ae
MMP_RS06895		-1.2	-1.9	selenocysteine-specific translation elongation factor
MMP_RS06230		-1.2	-2.5	helix-turn-helix domain-containing protein
MMP_RS04215		-1.2	-6.1	nickel pincer cofactor biosynthesis protein LarB
MMP_RS01755		-1.2	-1.1	DUF2097 domain-containing protein
MMP_RS08790		-1.2	-1.9	translation initiation factor IF-2 subunit alpha
MMP_RS06370		-1.2	-3.9	biotin synthase BioB
MMP_RS06700		-1.2	-6.7	hypothetical protein
MMP_RS07645		-1.1	-5.2	aldehyde dehydrogenase family protein
MMP_RS08100		-1.1	-4.7	8-amino-7-oxononanoate synthase
MMP_RS05265		-1.1	-1.7	2-isopropylmalate synthase
MMP_RS03400		-1.1	-2.3	archease
MMP_RS02900		-1.1	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01720		-1.1	-1.3	replication factor C large subunit
MMP_RS05085		-1.1	-4.6	AAA family ATPase
MMP_RS05090		-1.1	-5.4	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS01610		-1.1	-2.2	hypothetical protein
MMP_RS05070		-1.1	-5.4	4Fe-4S dicluster domain-containing protein
MMP_RS03390		-1.1	-4.7	malate dehydrogenase
MMP_RS07195		-1.1	-6.4	M20 family metallo-hydrolase
MMP_RS05065		-1.1	-3.4	CooT family nickel-binding protein
MMP_RS06730		-1.1	-1.9	phosphopantothenate/pantothenate synthetase
MMP_RS05055		-1.1	-7.8	DUF166 domain-containing protein
MMP_RS06485		-1.1	-0.9	zinc ribbon domain-containing protein
MMP_RS07525		-1.1	-5.3	4Fe-4S binding protein
MMP_RS06285		-1.1	-1.9	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS00750		-1.0	-1.8	fumarate hydratase
MMP_RS03155		-1.0	-5.0	precorrin-6A reductase
MMP_RS07355		-1.0	-0.9	transcription factor S
MMP_RS04055		-1.0	-1.4	hypothetical protein
MMP_RS01700		-1.0	-0.9	dihydroxy-acid dehydratase
MMP_RS03250		-1.0	-2.2	MJ1244 family protein
MMP_RS06375		-1.0	-4.4	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS08820		-1.0	-2.4	hypothetical protein
MMP_RS03025		-1.0	-3.9	molybdenum cofactor guanylyltransferase
MMP_RS07350		-1.0	-1.7	preprotein translocase subunit Sec61beta
MMP_RS07185		-1.0	-7.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS01325		-1.0	-1.8	dihydroneopterin aldolase family protein
MMP_RS04890		-1.0	-0.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS06345		-1.0	-4.8	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS05555		-1.0	-1.0	DUF4040 domain-containing protein
MMP_RS07750		-1.0	-2.8	DUF357 domain-containing protein
MMP_RS07955		-1.0	-3.5	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS08350		-0.9	-0.8	hypothetical protein
MMP_RS02875		-0.9	-5.3	chorismate pyruvate-lyase family protein
MMP_RS03140		-0.9	-6.4	hypothetical protein
MMP_RS01020		-0.9	-0.8	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS00515		-0.9	-0.7	DUF655 domain-containing protein
MMP_RS03700		-0.9	-4.3	sodium:proton antiporter
MMP_RS08645		-0.9	-4.0	UPF0179 family protein
MMP_RS04780		-0.9	-1.8	ribonuclease P
MMP_RS08165		-0.9	-2.0	phosphoglycerate dehydrogenase
MMP_RS04775		-0.9	-2.2	adenosylhomocysteinase
MMP_RS08635		-0.9	-1.3	UbiA family prenyltransferase
MMP_RS08335		-0.9	-4.1	NADH-quinone oxidoreductase subunit B family protein
MMP_RS08320		-0.9	-3.4	molybdopterin molybdotransferase MoeA
MMP_RS07735		-0.9	-0.6	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS03535		-0.9	-1.6	helix-turn-helix transcriptional regulator
MMP_RS03910		-0.9	-1.7	hypothetical protein
MMP_RS07605		-0.9	-1.4	diadenylate cyclase
MMP_RS05925		-0.9	-2.3	small nuclear ribonucleoprotein
MMP_RS04685		-0.9	-2.1	DUF126 domain-containing protein
MMP_RS00520		-0.9	-1.2	RNA polymerase Rpb4 family protein
MMP_RS06680		-0.9	-4.6	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06475		-0.8	-2.7	FAD-dependent oxidoreductase
MMP_RS03145		-0.8	-3.6	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS01800		-0.8	-2.2	TIGR00303 family protein
MMP_RS00730		-0.8	-3.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06325		-0.8	-1.1	hypothetical protein
MMP_RS08240		-0.8	-3.1	methanogenesis marker 16 metalloprotein
MMP_RS07545		-0.8	-0.8	HTH domain-containing protein
MMP_RS02280		-0.8	-0.6	DUF211 domain-containing protein
MMP_RS08995		-0.8	-1.1	hypothetical protein
MMP_RS03585		-0.8	-2.5	Hsp20/alpha crystallin family protein
MMP_RS04850		-0.8	-6.2	UPF0254 family protein
MMP_RS00770		-0.8	-2.9	hypothetical protein
MMP_RS01085		-0.8	-1.3	hypothetical protein
MMP_RS00895		-0.8	-2.4	hypothetical protein
MMP_RS07600		-0.8	-1.6	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS08365		-0.8	-2.9	energy conserving hydrogenase EhbF
MMP_RS07710		-0.8	-5.0	cell division protein FtsZ
MMP_RS06885		-0.8	-1.7	50S ribosome-binding GTPase
MMP_RS08370		-0.8	-0.5	cation:proton antiporter subunit C
MMP_RS01795		-0.8	-1.0	methanogenesis marker 6 protein
MMP_RS07200		-0.8	-3.2	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS02190		-0.8	-2.0	sulfopyruvate decarboxylase subunit alpha
MMP_RS07445		-0.8	-3.5	helix-turn-helix domain-containing protein
MMP_RS07540		-0.8	-2.1	CBS domain-containing protein
MMP_RS00810		-0.8	-3.4	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS06865		-0.7	-1.7	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS03465		-0.7	-0.9	adenine phosphoribosyltransferase
MMP_RS03395		-0.7	-2.2	hypothetical protein
MMP_RS08830		-0.7	-3.0	GTP-binding protein
MMP_RS00315		-0.7	-2.0	Nif3-like dinuclear metal center hexameric protein
MMP_RS05540		-0.7	-2.1	hypothetical protein
MMP_RS05930		-0.7	-1.6	3-isopropylmalate dehydratase large subunit
MMP_RS08415		-0.7	-2.3	radical SAM protein
MMP_RS00620		-0.7	-2.9	4Fe-4S binding protein
MMP_RS08650		-0.7	-1.7	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS02495		-0.7	-1.6	hypothetical protein
MMP_RS07385		-0.7	-1.4	protein translocase SEC61 complex subunit gamma
MMP_RS07700		-0.7	-4.3	DUF1188 domain-containing protein
MMP_RS00120		-0.7	-2.3	LysR family transcriptional regulator
MMP_RS08345		-0.7	-4.7	4Fe-4S binding protein
MMP_RS01110		-0.7	-1.6	FmdE family protein
MMP_RS01260		-0.7	-2.4	HDIG domain-containing protein
MMP_RS01840		-0.7	-3.6	TIGR00289 family protein
MMP_RS00725		-0.7	-2.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS04785		-0.7	-4.6	hypothetical protein
MMP_RS00320		-0.7	-1.2	class I SAM-dependent methyltransferase
MMP_RS00305		-0.7	-0.9	phosphoribosyl-ATP diphosphatase
MMP_RS00475		-0.7	-3.1	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS05950		-0.7	-3.4	nickel-dependent hydrogenase large subunit
MMP_RS03225		-0.7	-2.2	acetolactate decarboxylase
MMP_RS05765		-0.7	-2.4	M42 family metallopeptidase
MMP_RS07075		-0.6	-2.0	phosphomannomutase/phosphoglucomutase
MMP_RS00695		-0.6	-0.6	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS04585		-0.6	-3.9	AIR synthase related protein
MMP_RS05920		-0.6	-0.4	50S ribosomal protein L37e
MMP_RS07720		-0.6	-4.4	4Fe-4S binding protein
MMP_RS07705		-0.6	-4.3	transcriptional regulator
MMP_RS00985		-0.6	-3.2	CDC48 family AAA ATPase
MMP_RS05875		-0.6	-1.7	hydroxyethylthiazole kinase
MMP_RS06630		-0.6	-0.5	UPF0058 family protein
MMP_RS00295		-0.6	-1.1	gamma carbonic anhydrase family protein
MMP_RS01725		-0.6	-2.0	class I SAM-dependent methyltransferase family protein
MMP_RS07425		-0.6	-2.3	GTP-binding protein
MMP_RS02130		-0.6	-2.4	zinc metalloprotease HtpX
MMP_RS05250		-0.6	-0.6	NFYB/HAP3 family transcription factor subunit
MMP_RS07365		-0.6	-4.7	2-phosphoglycerate kinase
MMP_RS04420		-0.6	-2.7	LysE family translocator
MMP_RS02800		-0.6	-2.0	nucleotidyltransferase domain-containing protein
MMP_RS04875		-0.6	-1.8	energy-converting hydrogenase B subunit P
MMP_RS06860		-0.6	-1.0	4Fe-4S binding protein
MMP_RS07755		-0.6	-0.6	DUF555 domain-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments