Experiment set4IT034 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07845		-2.7	-3.6	LL-diaminopimelate aminotransferase
MMP_RS09020		-2.3	-2.2	hypothetical protein
MMP_RS00130		-2.1	-1.6	nickel-responsive transcriptional regulator NikR
MMP_RS01700		-2.1	-1.4	dihydroxy-acid dehydratase
MMP_RS02900		-2.1	-0.9	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS07345		-2.0	-5.6	glycine synthesis protein GlyXL (from data)
MMP_RS05515		-2.0	-6.8	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS08720		-1.9	-1.7	4Fe-4S binding protein
MMP_RS04615		-1.9	-4.9	PDGLE domain-containing protein
MMP_RS01225		-1.9	-6.2	DUF5379 domain-containing protein
MMP_RS03435		-1.9	-2.1	ketol-acid reductoisomerase
MMP_RS03035		-1.9	-3.6	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS07730		-1.9	-2.0	pyruvate synthase subunit beta
MMP_RS04605		-1.9	-4.5	cobalt ECF transporter T component CbiQ
MMP_RS01005		-1.9	-1.7	riboflavin synthase
MMP_RS04620		-1.7	-10.6	cobalt transporter CbiM
MMP_RS03015		-1.7	-8.3	GTP 3' 8-cyclase MoaA
MMP_RS00750		-1.7	-3.0	fumarate hydratase
MMP_RS05555		-1.7	-1.6	DUF4040 domain-containing protein
MMP_RS06285		-1.7	-3.0	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS03450		-1.7	-2.9	glycine synthesis protein GlyXS (from data)
MMP_RS01175		-1.7	-4.4	triphosphoribosyl-dephospho-CoA synthase
MMP_RS01265		-1.7	-2.8	hypothetical protein
MMP_RS06270		-1.7	-7.1	TIGR00300 family protein
MMP_RS00695		-1.7	-1.0	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS01500		-1.6	-2.7	CBS domain-containing protein
MMP_RS08745		-1.6	-7.5	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06355		-1.6	-2.6	molybdenum cofactor biosynthesis protein MoaE
MMP_RS05500		-1.6	-8.4	2-isopropylmalate synthase
MMP_RS07635		-1.6	-7.1	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS06350		-1.6	-7.1	HesA/MoeB/ThiF family protein
MMP_RS07735		-1.6	-1.0	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS08165		-1.6	-2.2	phosphoglycerate dehydrogenase
MMP_RS02135		-1.6	-4.8	DUF5612 domain-containing protein
MMP_RS02010		-1.5	-6.9	PHP domain-containing protein
MMP_RS08105		-1.5	-6.9	6-carboxyhexanoate--CoA ligase
MMP_RS05920		-1.5	-0.7	50S ribosomal protein L37e
MMP_RS01020		-1.5	-1.0	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS01755		-1.5	-1.3	DUF2097 domain-containing protein
MMP_RS08210		-1.4	-2.5	phosphatidylglycerophosphatase A
MMP_RS00735		-1.4	-3.7	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS05425		-1.4	-4.7	monovalent cation/H+ antiporter complex subunit F
MMP_RS06400		-1.4	-1.7	4Fe-4S binding protein
MMP_RS01455		-1.4	-6.2	nickel pincer cofactor biosynthesis protein LarC
MMP_RS04500		-1.3	-9.6	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS07955		-1.3	-5.5	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS05095		-1.3	-7.8	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS05085		-1.3	-8.2	AAA family ATPase
MMP_RS03250		-1.3	-2.9	MJ1244 family protein
MMP_RS06340		-1.3	-5.9	phosphoadenosine phosphosulfate reductase family protein
MMP_RS07600		-1.3	-2.9	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS05930		-1.3	-2.3	3-isopropylmalate dehydratase large subunit
MMP_RS08330		-1.3	-5.0	NADH-quinone oxidoreductase subunit H
MMP_RS04775		-1.3	-3.6	adenosylhomocysteinase
MMP_RS06295		-1.3	-6.1	methanogenesis marker 14 protein
MMP_RS02885		-1.3	-9.8	molybdopterin biosynthesis protein
MMP_RS05080		-1.3	-8.1	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS05060		-1.3	-9.8	AAA family ATPase
MMP_RS08320		-1.3	-4.6	molybdopterin molybdotransferase MoeA
MMP_RS02235		-1.3	-8.4	CBS domain-containing protein
MMP_RS06105		-1.2	-6.9	hydrogenase maturation peptidase HycI
MMP_RS06370		-1.2	-4.4	biotin synthase BioB
MMP_RS05100		-1.2	-10.1	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS03390		-1.2	-6.5	malate dehydrogenase
MMP_RS04215		-1.2	-8.1	nickel pincer cofactor biosynthesis protein LarB
MMP_RS05075		-1.2	-9.6	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMP_RS07645		-1.2	-4.1	aldehyde dehydrogenase family protein
MMP_RS00305		-1.2	-1.6	phosphoribosyl-ATP diphosphatase
MMP_RS03640		-1.2	-3.1	archaeal proteasome endopeptidase complex subunit beta
MMP_RS01830		-1.2	-1.8	tRNA-Val
MMP_RS05090		-1.2	-7.7	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS03600		-1.2	-2.2	triose-phosphate isomerase
MMP_RS08725		-1.2	-2.1	Ni/Fe hydrogenase subunit alpha
MMP_RS06120		-1.2	-1.9	UPF0147 family protein
MMP_RS05265		-1.2	-2.0	2-isopropylmalate synthase
MMP_RS02355		-1.2	-2.4	30S ribosomal protein S27ae
MMP_RS02195		-1.2	-3.3	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS04790		-1.2	-9.1	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS05070		-1.1	-5.6	4Fe-4S dicluster domain-containing protein
MMP_RS00685		-1.1	-3.1	2-phospho-L-lactate guanylyltransferase
MMP_RS05065		-1.1	-4.1	CooT family nickel-binding protein
MMP_RS08095		-1.1	-5.4	dethiobiotin synthase
MMP_RS01385		-1.1	-0.6	imidazole glycerol phosphate synthase subunit HisH
MMP_RS07545		-1.1	-0.9	HTH domain-containing protein
MMP_RS02805		-1.1	-1.3	HEPN domain-containing protein
MMP_RS06680		-1.1	-6.1	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS03315		-1.1	-0.9	ferrous iron transport protein A
MMP_RS01610		-1.1	-2.1	hypothetical protein
MMP_RS01545		-1.1	-1.0	CBS domain-containing protein
MMP_RS01220		-1.1	-4.5	hypothetical protein
MMP_RS05055		-1.0	-7.8	DUF166 domain-containing protein
MMP_RS08100		-1.0	-5.9	8-amino-7-oxononanoate synthase
MMP_RS04055		-1.0	-1.5	hypothetical protein
MMP_RS06700		-1.0	-6.6	hypothetical protein
MMP_RS00295		-1.0	-1.1	gamma carbonic anhydrase family protein
MMP_RS03700		-1.0	-5.4	sodium:proton antiporter
MMP_RS02495		-1.0	-2.3	hypothetical protein
MMP_RS01795		-1.0	-1.2	methanogenesis marker 6 protein
MMP_RS07185		-1.0	-7.6	pyridoxal phosphate-dependent aminotransferase
MMP_RS08820		-1.0	-3.7	hypothetical protein
MMP_RS07575		-1.0	-3.0	RNA ligase partner protein
MMP_RS07750		-1.0	-3.7	DUF357 domain-containing protein
MMP_RS07195		-1.0	-6.6	M20 family metallo-hydrolase
MMP_RS03140		-1.0	-7.1	hypothetical protein
MMP_RS06630		-1.0	-0.9	UPF0058 family protein
MMP_RS06230		-1.0	-2.4	helix-turn-helix domain-containing protein
MMP_RS03095		-0.9	-3.9	diphthine synthase
MMP_RS08355		-0.9	-4.2	Na(+)/H(+) antiporter subunit B
MMP_RS02240		-0.9	-1.7	methanogenesis marker 7 protein
MMP_RS08350		-0.9	-0.8	hypothetical protein
MMP_RS01250		-0.9	-3.0	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS01720		-0.9	-1.9	replication factor C large subunit
MMP_RS04780		-0.9	-1.9	ribonuclease P
MMP_RS06705		-0.9	-4.5	formate/nitrite transporter family protein
MMP_RS05430		-0.9	-3.3	TIGR00288 family NYN domain-containing protein
MMP_RS05540		-0.9	-2.3	hypothetical protein
MMP_RS05925		-0.9	-2.2	small nuclear ribonucleoprotein
MMP_RS06475		-0.9	-3.3	FAD-dependent oxidoreductase
MMP_RS04875		-0.9	-3.7	energy-converting hydrogenase B subunit P
MMP_RS06375		-0.9	-2.8	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS00985		-0.9	-3.9	CDC48 family AAA ATPase
MMP_RS06625		-0.9	-1.6	DNA primase
MMP_RS00300		-0.9	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06315		-0.9	-0.7	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS02280		-0.8	-0.6	DUF211 domain-containing protein
MMP_RS02800		-0.8	-3.5	nucleotidyltransferase domain-containing protein
MMP_RS08595		-0.8	-0.7	flagellar protein C
MMP_RS00895		-0.8	-3.1	hypothetical protein
MMP_RS03420		-0.8	-2.1	acetolactate synthase small subunit
MMP_RS04850		-0.8	-6.5	UPF0254 family protein
MMP_RS01195		-0.8	-0.9	metalloregulator ArsR/SmtB family transcription factor
MMP_RS08240		-0.8	-3.6	methanogenesis marker 16 metalloprotein
MMP_RS01240		-0.8	-1.0	7-cyano-7-deazaguanine synthase QueC
MMP_RS08995		-0.8	-1.1	hypothetical protein
MMP_RS06020		-0.8	-2.5	archaeoflavoprotein AfpA
MMP_RS07525		-0.8	-4.2	4Fe-4S binding protein
MMP_RS01800		-0.8	-1.8	TIGR00303 family protein
MMP_RS03025		-0.8	-3.2	molybdenum cofactor guanylyltransferase
MMP_RS07445		-0.8	-4.1	helix-turn-helix domain-containing protein
MMP_RS04265		-0.8	-1.9	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS01325		-0.8	-1.4	dihydroneopterin aldolase family protein
MMP_RS07720		-0.8	-6.0	4Fe-4S binding protein
MMP_RS00315		-0.8	-3.0	Nif3-like dinuclear metal center hexameric protein
MMP_RS06345		-0.8	-3.1	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07630		-0.8	-1.0	ATP-binding cassette domain-containing protein
MMP_RS04685		-0.8	-2.0	DUF126 domain-containing protein
MMP_RS07380		-0.8	-1.5	transcription elongation factor Spt5
MMP_RS05950		-0.8	-5.6	nickel-dependent hydrogenase large subunit
MMP_RS07695		-0.8	-2.8	DUF3236 domain-containing protein
MMP_RS02935		-0.8	-2.6	A24 family peptidase
MMP_RS02875		-0.7	-4.9	chorismate pyruvate-lyase family protein
MMP_RS03145		-0.7	-3.5	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS00725		-0.7	-3.3	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS00120		-0.7	-1.8	LysR family transcriptional regulator
MMP_RS02130		-0.7	-3.8	zinc metalloprotease HtpX
MMP_RS04890		-0.7	-0.5	adenylyltransferase/cytidyltransferase family protein
MMP_RS08645		-0.7	-4.0	UPF0179 family protein
MMP_RS06895		-0.7	-0.9	selenocysteine-specific translation elongation factor
MMP_RS07705		-0.7	-4.5	transcriptional regulator
MMP_RS03155		-0.7	-2.9	precorrin-6A reductase
MMP_RS07350		-0.7	-1.4	preprotein translocase subunit Sec61beta
MMP_RS08715		-0.7	-1.0	formylmethanofuran dehydrogenase subunit B
MMP_RS00810		-0.7	-3.1	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS03080		-0.7	-1.6	universal stress protein
MMP_RS00730		-0.7	-2.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06770		-0.7	-3.6	DHH family phosphoesterase
MMP_RS05845		-0.7	-1.2	tRNA-intron lyase
MMP_RS00345		-0.7	-2.1	DUF2666 domain-containing protein
MMP_RS07710		-0.7	-3.4	cell division protein FtsZ
MMP_RS05815		-0.7	-1.2	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06720		-0.7	-3.2	response regulator transcription factor
MMP_RS02995		-0.7	-2.5	acyl-CoA thioesterase
MMP_RS00110		-0.7	-1.4	hypothetical protein
MMP_RS03580		-0.7	-2.1	signal recognition particle-docking protein FtsY
MMP_RS09055		-0.7	-0.6	CAP domain-containing protein
MMP_RS05850		-0.7	-2.6	Ldh family oxidoreductase
MMP_RS01380		-0.7	-2.8	PHP domain-containing protein
MMP_RS03205		-0.7	-0.7	peptidyl-tRNA hydrolase Pth2
MMP_RS06215		-0.7	-1.0	30S ribosomal protein S6e
MMP_RS07200		-0.6	-2.8	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS02695		-0.6	-4.1	formylmethanofuran dehydrogenase subunit A
MMP_RS08830		-0.6	-3.6	GTP-binding protein
MMP_RS06685		-0.6	-4.3	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS00770		-0.6	-2.5	hypothetical protein
MMP_RS04585		-0.6	-3.9	AIR synthase related protein
MMP_RS07540		-0.6	-2.3	CBS domain-containing protein
MMP_RS08655		-0.6	-4.4	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01675		-0.6	-1.0	hypothetical protein
MMP_RS03445		-0.6	-0.5	methanogenesis marker 17 protein
MMP_RS01840		-0.6	-3.7	TIGR00289 family protein
MMP_RS08360		-0.6	-2.2	hypothetical protein
MMP_RS07700		-0.6	-3.0	DUF1188 domain-containing protein
MMP_RS08345		-0.6	-3.6	4Fe-4S binding protein
MMP_RS03910		-0.6	-1.5	hypothetical protein
MMP_RS06730		-0.6	-0.8	phosphopantothenate/pantothenate synthetase
MMP_RS04785		-0.6	-4.1	hypothetical protein
MMP_RS06130		-0.6	-1.4	peptidylprolyl isomerase
MMP_RS07355		-0.6	-0.5	transcription factor S
MMP_RS01415		-0.6	-2.1	DUF2067 domain-containing protein
MMP_RS01790		-0.6	-2.6	restriction endonuclease

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments