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Experiment set4IT034 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS03615
+2.8
17.4
4Fe-4S binding protein
compare
MMP
_RS03620
+2.8
16.7
hypothetical protein
compare
MMP
_RS04550
+1.9
13.6
S-layer protein
compare
MMP
_RS08930
+1.2
2.2
hypothetical protein
compare
MMP
_RS03300
+1.0
1.3
TOBE domain-containing protein
compare
MMP
_RS08775
+1.0
5.4
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS02470
+1.0
0.9
helix-turn-helix transcriptional regulator
compare
MMP
_RS05250
+1.0
1.7
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS05970
+0.9
3.1
class II SORL domain-containing protein
compare
MMP
_RS01940
+0.9
3.5
MoxR family ATPase
compare
MMP
_RS08860
+0.9
3.1
MinD/ParA family protein
compare
MMP
_RS07890
+0.9
2.7
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS09025
+0.9
1.3
hypothetical protein
compare
MMP
_RS07840
+0.8
2.7
ribonuclease III
compare
MMP
_RS02490
+0.8
2.6
hypothetical protein
compare
MMP
_RS04520
+0.8
1.8
nucleoside deaminase
compare
MMP
_RS00240
+0.8
5.6
type II secretion system F family protein
compare
MMP
_RS06070
+0.8
4.6
iron ABC transporter substrate-binding protein
compare
MMP
_RS00395
+0.8
1.6
MGMT family protein
compare
MMP
_RS01310
+0.7
4.8
hypothetical protein
compare
MMP
_RS06540
+0.7
1.6
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS08855
+0.7
3.5
hypothetical protein
compare
MMP
_RS01055
+0.7
2.9
hypothetical protein
compare
MMP
_RS02415
+0.7
2.2
site-specific integrase
compare
MMP
_RS00325
+0.7
1.2
RNA-binding protein
compare
MMP
_RS00990
+0.7
3.0
hypothetical protein
compare
MMP
_RS01750
+0.6
4.1
DUF63 family protein
compare
MMP
_RS02605
+0.6
0.7
MotA/TolQ/ExbB proton channel family protein
compare
MMP
_RS07125
+0.6
2.4
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS01295
+0.6
4.1
hypothetical protein
compare
MMP
_RS07330
+0.6
5.4
membrane protein
compare
MMP
_RS01290
+0.6
4.1
class III signal peptide-containing protein
compare
MMP
_RS06765
+0.6
2.8
flap endonuclease-1
compare
MMP
_RS01885
+0.6
3.7
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS01280
+0.6
4.5
DUF515 domain-containing protein
compare
MMP
_RS06525
+0.6
1.0
YciI family protein
compare
MMP
_RS05635
+0.6
3.8
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS02595
+0.6
1.1
putative zinc-binding protein
compare
MMP
_RS03220
+0.6
1.8
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS06585
+0.6
1.3
DMT family protein
compare
MMP
_RS01285
+0.6
3.2
hypothetical protein
compare
MMP
_RS06990
+0.6
2.4
CatB-related O-acetyltransferase
compare
MMP
_RS06910
+0.6
2.9
RlmF-related methyltransferase
compare
MMP
_RS01305
+0.6
4.6
hypothetical protein
compare
MMP
_RS05020
+0.6
1.3
hypothetical protein
compare
MMP
_RS08980
+0.6
2.0
hypothetical protein
compare
MMP
_RS06920
+0.5
3.5
AAA family ATPase
compare
MMP
_RS02265
+0.5
2.0
nitroreductase family protein
compare
MMP
_RS02475
+0.5
1.8
hypothetical protein
compare
MMP
_RS02370
+0.5
2.2
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS06365
+0.5
1.6
hypothetical protein
compare
MMP
_RS04145
+0.5
1.1
hypothetical protein
compare
MMP
_RS00245
+0.5
4.2
type II secretion system F family protein
compare
MMP
_RS08315
+0.5
0.9
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS06500
+0.5
3.0
ATP-binding protein
compare
MMP
_RS07560
+0.5
2.2
prefoldin subunit alpha
compare
MMP
_RS08215
+0.5
1.1
DUF483 domain-containing protein
compare
MMP
_RS01275
+0.5
2.1
class III signal peptide-containing protein
compare
MMP
_RS04090
+0.5
1.6
hypothetical protein
compare
MMP
_RS03090
+0.5
2.3
cation:proton antiporter
compare
MMP
_RS08275
+0.5
2.9
hypothetical protein
compare
MMP
_RS07860
+0.5
0.4
hypothetical protein
compare
MMP
_RS06905
+0.5
0.8
hypothetical protein
compare
MMP
_RS07770
+0.5
1.9
alanine racemase
compare
MMP
_RS00150
+0.5
2.2
AAA family ATPase
compare
MMP
_RS06530
+0.5
1.8
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMP
_RS04060
+0.5
1.7
hypothetical protein
compare
MMP
_RS04305
+0.5
1.4
hypothetical protein
compare
MMP
_RS06520
+0.5
1.7
DUF1786 domain-containing protein
compare
MMP
_RS08090
+0.5
2.2
hypothetical protein
compare
MMP
_RS03385
+0.4
0.6
cation diffusion facilitator family transporter
compare
MMP
_RS01460
+0.4
1.4
hypothetical protein
compare
MMP
_RS03625
+0.4
1.9
cell wall-binding protein
compare
MMP
_RS02450
+0.4
1.8
hypothetical protein
compare
MMP
_RS01880
+0.4
2.6
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS03490
+0.4
0.8
DUF2115 domain-containing protein
compare
MMP
_RS06550
+0.4
1.8
AMP-binding protein
compare
MMP
_RS02175
+0.4
0.4
DUF1611 domain-containing protein
compare
MMP
_RS08620
+0.4
2.0
flagellar accessory protein FlaH
compare
MMP
_RS09045
+0.4
3.0
class III signal peptide-containing protein
compare
MMP
_RS05825
+0.4
1.2
peptidyl-prolyl cis-trans isomerase
compare
MMP
_RS02955
+0.4
1.1
DJ-1/PfpI family protein
compare
MMP
_RS07905
+0.4
1.5
DUF3343 domain-containing protein
compare
MMP
_RS03520
+0.4
0.8
YwbE family protein
compare
MMP
_RS03840
+0.4
2.0
hypothetical protein
compare
MMP
_RS01100
+0.4
0.8
ABC transporter ATP-binding protein
compare
MMP
_RS03440
+0.4
0.6
MoaD/ThiS family protein
compare
MMP
_RS06035
+0.4
2.7
glycosyltransferase family 2 protein
compare
MMP
_RS07130
+0.4
2.6
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS01620
+0.4
1.9
hypothetical protein
compare
MMP
_RS06440
+0.4
2.4
CBS domain-containing protein
compare
MMP
_RS06870
+0.4
1.2
DedA family protein
compare
MMP
_RS06545
+0.4
1.4
ferredoxin family protein
compare
MMP
_RS03870
+0.4
1.6
purine NTPase
compare
MMP
_RS01315
+0.4
3.5
DUF2341 domain-containing protein
compare
MMP
_RS03125
+0.4
1.7
cell division ATPase MinD
compare
MMP
_RS08670
+0.4
2.0
metallophosphoesterase
compare
MMP
_RS01095
+0.4
1.4
iron ABC transporter permease
compare
MMP
_RS06175
+0.4
1.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS06610
+0.4
1.6
DUF2334 domain-containing protein
compare
MMP
_RS00960
+0.4
1.3
iron export ABC transporter permease subunit FetB
compare
MMP
_RS04105
+0.4
1.8
MarR family transcriptional regulator
compare
MMP
_RS02870
+0.4
1.8
hypothetical protein
compare
MMP
_RS08200
+0.4
2.3
archaeosine synthase subunit alpha
compare
MMP
_RS01270
+0.4
2.6
prepilin peptidase
compare
MMP
_RS06150
+0.4
2.4
hypothetical protein
compare
MMP
_RS04050
+0.4
1.5
hypothetical protein
compare
MMP
_RS07895
+0.4
0.9
cytochrome c
compare
MMP
_RS07180
+0.4
1.9
DEAD/DEAH box helicase
compare
MMP
_RS01130
+0.4
1.5
flavoprotein
compare
MMP
_RS02390
+0.3
1.3
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS01120
+0.3
1.6
permease
compare
MMP
_RS06940
+0.3
1.2
polyprenyl diphosphate synthase
compare
MMP
_RS09030
+0.3
1.6
hypothetical protein
compare
MMP
_RS05790
+0.3
1.5
HDIG domain-containing protein
compare
MMP
_RS07925
+0.3
0.7
haloacid dehalogenase
compare
MMP
_RS05785
+0.3
2.3
ATP-binding protein
compare
MMP
_RS05355
+0.3
0.4
hypothetical protein
compare
MMP
_RS07815
+0.3
0.5
DUF2120 domain-containing protein
compare
MMP
_RS03765
+0.3
1.8
CopG family ribbon-helix-helix protein
compare
MMP
_RS03540
+0.3
1.6
DUF2178 domain-containing protein
compare
MMP
_RS07100
+0.3
2.2
hypothetical protein
compare
MMP
_RS00250
+0.3
2.6
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS08665
+0.3
2.3
hypothetical protein
compare
MMP
_RS01950
+0.3
1.9
hypothetical protein
compare
MMP
_RS03235
+0.3
0.9
tRNA pseudouridine(13) synthase TruD
compare
MMP
_RS01495
+0.3
1.6
TraB/GumN family protein
compare
MMP
_RS02675
+0.3
1.0
hypothetical protein
compare
MMP
_RS04120
+0.3
1.9
hypothetical protein
compare
MMP
_RS08130
+0.3
2.0
IGHMBP2 family helicase
compare
MMP
_RS08785
+0.3
0.4
RNA-protein complex protein Nop10
compare
MMP
_RS07650
+0.3
1.7
TldD/PmbA family protein
compare
MMP
_RS03275
+0.3
1.0
TIGR00266 family protein
compare
MMP
_RS02890
+0.3
1.5
TIGR00296 family protein
compare
MMP
_RS06710
+0.3
1.2
selenium-binding protein
compare
MMP
_RS02795
+0.3
1.4
sulfate permease
compare
MMP
_RS07085
+0.3
1.7
ribonuclease HII
compare
MMP
_RS01515
+0.3
1.9
PINc/VapC family ATPase
compare
MMP
_RS07835
+0.3
1.3
TldD/PmbA family protein
compare
MMP
_RS06140
+0.3
0.8
radical SAM protein
compare
MMP
_RS01370
+0.3
1.7
acetate--CoA ligase family protein
compare
MMP
_RS06840
+0.3
0.3
DNA-directed RNA polymerase subunit N
compare
MMP
_RS03885
+0.3
2.0
tyrosine-type recombinase/integrase
compare
MMP
_RS01930
+0.3
2.2
hypothetical protein
compare
MMP
_RS08640
+0.3
1.8
TIM barrel protein
compare
MMP
_RS03020
+0.3
1.0
peptidylprolyl isomerase
compare
MMP
_RS00675
+0.3
0.3
nitroreductase family protein
compare
MMP
_RS07075
+0.3
1.2
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS04945
+0.3
1.1
hypothetical protein
compare
MMP
_RS06915
+0.3
0.7
metallophosphoesterase
compare
MMP
_RS05695
+0.3
1.3
phospholipase D-like domain-containing protein
compare
MMP
_RS08630
+0.3
1.5
archaellar assembly protein FlaJ
compare
MMP
_RS02305
+0.3
1.5
DUF378 domain-containing protein
compare
MMP
_RS07805
+0.3
1.4
ABC transporter permease
compare
MMP
_RS01805
+0.3
0.9
NUDIX hydrolase
compare
MMP
_RS06010
+0.3
1.9
heavy metal translocating P-type ATPase
compare
MMP
_RS07140
+0.3
2.0
TIGR00341 family protein
compare
MMP
_RS04205
+0.3
1.0
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS05325
+0.3
1.4
hypothetical protein
compare
MMP
_RS01980
+0.3
1.5
trimeric intracellular cation channel family protein
compare
MMP
_RS04020
+0.3
0.9
hypothetical protein
compare
MMP
_RS00880
+0.3
1.2
ribosome assembly RNA-binding protein YhbY
compare
MMP
_RS01945
+0.3
1.7
DUF4350 domain-containing protein
compare
MMP
_RS00320
+0.3
0.5
class I SAM-dependent methyltransferase
compare
MMP
_RS00940
+0.3
1.7
daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
compare
MMP
_RS06005
+0.3
1.1
heavy-metal-associated domain-containing protein
compare
MMP
_RS08675
+0.3
0.6
class III signal peptide-containing protein
compare
MMP
_RS03065
+0.3
0.8
AzlC family ABC transporter permease
compare
MMP
_RS05820
+0.3
1.1
RNA-binding transcriptional accessory protein
compare
MMP
_RS03675
+0.3
1.4
RimK family alpha-L-glutamate ligase
compare
MMP
_RS02540
+0.3
1.4
DUF2283 domain-containing protein
compare
MMP
_RS01865
+0.3
0.5
GPR1/FUN34/YaaH family transporter
compare
MMP
_RS02915
+0.2
1.1
amino acid ABC transporter permease
compare
MMP
_RS06225
+0.2
1.5
DNA double-strand break repair nuclease NurA
compare
MMP
_RS05720
+0.2
0.8
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS03150
+0.2
1.4
phosphoglycerate mutase
compare
MMP
_RS06055
+0.2
1.1
peroxiredoxin
compare
MMP
_RS07145
+0.2
1.1
AmmeMemoRadiSam system protein B
compare
MMP
_RS01745
+0.2
0.8
AMP phosphorylase
compare
MMP
_RS06335
+0.2
1.0
HAD family hydrolase
compare
MMP
_RS01210
+0.2
1.6
sodium:solute symporter
compare
MMP
_RS02480
+0.2
0.5
hypothetical protein
compare
MMP
_RS08260
+0.2
1.3
DUF99 family protein
compare
MMP
_RS04960
+0.2
1.5
cytochrome c biogenesis CcdA family protein
compare
MMP
_RS00955
+0.2
1.5
coenzyme gamma-F420-2:alpha-L-glutamate ligase
compare
MMP
_RS04840
+0.2
1.4
response regulator
compare
MMP
_RS00935
+0.2
1.6
MATE family efflux transporter
compare
MMP
_RS06000
+0.2
1.3
divalent-cation tolerance protein CutA
compare
MMP
_RS02825
+0.2
1.4
mechanosensitive ion channel family protein
compare
MMP
_RS01875
+0.2
1.5
N-acetyltransferase
compare
MMP
_RS08470
+0.2
1.1
ATP-binding cassette domain-containing protein
compare
MMP
_RS04285
+0.2
1.5
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS00185
+0.2
1.6
potassium channel protein
compare
MMP
_RS03670
+0.2
0.7
DUF1890 domain-containing protein
compare
MMP
_RS04430
+0.2
1.4
DUF1847 domain-containing protein
compare
MMP
_RS01660
+0.2
1.0
hypothetical protein
compare
MMP
_RS02410
+0.2
0.6
ABC transporter substrate-binding protein
compare
MMP
_RS01935
+0.2
1.5
DUF58 domain-containing protein
compare
MMP
_RS02635
+0.2
1.3
class I SAM-dependent methyltransferase
compare
MMP
_RS06080
+0.2
1.5
radical SAM protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments