Experiment set4IT030 for Shewanella loihica PV-4

Compare to:

LB with 5-Hydroxymethylfurfural 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_3311 +5.9 31.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3560 +5.7 29.4 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_0777 +5.7 7.7 two-component response regulator (RefSeq) compare
Shew_3561 +5.6 27.3 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_2049 +5.5 25.5 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_0296 +5.5 6.2 heat shock protein Hsp20 (RefSeq) compare
Shew_2572 +5.4 13.1 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_0459 +5.3 18.3 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_2637 +5.2 25.1 PII uridylyl-transferase (RefSeq) compare
Shew_0755 +5.0 16.3 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_3554 glnA +4.9 8.4 glutamine synthetase (RefSeq) compare
Shew_1058 +4.8 17.2 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_1301 +4.8 34.9 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_2382 +4.5 32.0 cysteine synthase A (RefSeq) compare
Shew_1224 +4.4 29.8 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1823 +4.4 9.1 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_1298 guaA +4.4 30.4 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1819 +4.3 11.2 GntR family transcriptional regulator (RefSeq) compare
Shew_1822 +4.2 16.7 aconitate hydratase (RefSeq) compare
Shew_2000 +3.8 6.3 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_1657 sucC +3.8 6.2 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_0763 +3.8 6.9 putative PAS/PAC sensor protein (RefSeq) compare
Shew_2770 +3.6 2.9 polyprenyl synthetase (RefSeq) compare
Shew_1341 +3.5 8.2 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_1425 +3.5 14.9 adenylyl-sulfate kinase (RefSeq) compare
Shew_0867 +3.4 4.2 malate dehydrogenase (RefSeq) compare
Shew_3273 +3.2 13.9 hypothetical protein (RefSeq) compare
Shew_1128 +3.2 16.4 LysR family transcriptional regulator (RefSeq) compare
Shew_2302 +3.2 16.5 amidophosphoribosyltransferase (RefSeq) compare
Shew_1512 +3.2 12.0 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_2320 +3.1 16.1 RNA methyltransferase (RefSeq) compare
Shew_3413 +3.0 19.2 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_1602 +3.0 4.4 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_3710 tdh +2.8 15.9 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_3488 +2.7 4.5 ribonuclease PH (RefSeq) compare
Shew_0728 +2.7 13.5 dihydroorotase (RefSeq) compare
Shew_1601 +2.7 3.9 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2410 +2.7 1.5 beta-ketoacyl synthase (RefSeq) compare
Shew_2502 +2.7 9.5 ABC transporter-related protein (RefSeq) compare
Shew_3691 +2.6 3.6 hypothetical protein (RefSeq) compare
Shew_1013 +2.6 14.7 aspartate carbamoyltransferase (RefSeq) compare
Shew_0534 +2.6 4.6 major facilitator transporter (RefSeq) compare
Shew_3709 +2.6 14.6 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1186 +2.6 3.2 transcriptional regulator NrdR (RefSeq) compare
Shew_1922 +2.5 9.6 phosphoglucomutase (RefSeq) compare
Shew_1302 +2.5 6.1 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_2481 +2.5 12.5 porin (RefSeq) compare
Shew_2895 +2.5 8.4 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_1402 +2.5 12.6 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_3708 +2.5 13.7 TetR family transcriptional regulator (RefSeq) compare
Shew_1287 +2.4 5.8 hypothetical protein (RefSeq) compare
Shew_0565 +2.4 4.3 tRNA delta(2)-isopentenylpyrophosphate transferase (RefSeq) compare
Shew_3487 pyrE +2.4 9.7 orotate phosphoribosyltransferase (RefSeq) compare
Shew_3065 +2.4 16.0 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_2174 +2.4 2.6 fatty acid metabolism regulator (RefSeq) compare
Shew_3718 +2.4 2.8 hypothetical protein (RefSeq) compare
Shew_0618 +2.4 2.5 hypothetical protein (RefSeq) compare
Shew_2008 +2.3 1.6 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1931 +2.3 3.0 alkylphosphonate utilization operon protein PhnA (RefSeq) compare
Shew_1820 prpB +2.3 2.4 2-methylisocitrate lyase (RefSeq) compare
Shew_3363 +2.3 3.5 3-dehydroquinate dehydratase, type II (RefSeq) compare
Shew_2571 +2.3 16.0 propionyl-CoA carboxylase (RefSeq) compare
Shew_3225 +2.3 9.1 glutathione synthetase (RefSeq) compare
Shew_0086 +2.3 15.2 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_3412 purH +2.3 13.6 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_3378 +2.3 3.7 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_2584 +2.2 9.8 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_0531 +2.2 4.8 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_3621 +2.2 1.5 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_3431 aceE +2.2 16.3 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_2812 deoD +2.2 9.1 purine nucleoside phosphorylase (RefSeq) compare
Shew_2573 +2.2 13.8 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_2837 +2.2 1.7 transcription elongation factor GreA (RefSeq) compare
Shew_3377 +2.2 1.7 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_0421 +2.1 1.5 phage shock protein C, PspC (RefSeq) compare
Shew_1810 +2.1 7.8 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_0613 +2.1 8.6 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_3440 +2.0 2.7 prepilin peptidase (RefSeq) compare
Shew_2498 +2.0 2.2 extracellular solute-binding protein (RefSeq) compare
Shew_2838 carB +2.0 14.3 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_1230 +2.0 4.1 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_3432 pdhR +2.0 4.1 transcriptional regulator PdhR (RefSeq) compare
Shew_2962 +1.9 5.1 malate dehydrogenase (RefSeq) compare
Shew_3295 +1.9 11.7 AFG1 family ATPase (RefSeq) compare
Shew_0950 +1.9 7.0 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2839 +1.9 13.6 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_2813 +1.9 3.3 phosphopentomutase (RefSeq) compare
Shew_0614 +1.9 5.7 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_2558 +1.8 2.3 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_1437 +1.8 11.6 transcriptional regulator, TyrR (RefSeq) compare
Shew_1227 +1.8 2.6 glutamate--cysteine ligase (RefSeq) compare
Shew_3499 +1.8 4.4 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_1210 +1.8 4.6 stationary-phase survival protein SurE (RefSeq) compare
Shew_0359 fre +1.8 7.4 FMN reductase (RefSeq) compare
Shew_1563 +1.8 12.2 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_3430 +1.8 2.3 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_2285 +1.8 1.4 UDP-glucose 4-epimerase (RefSeq) compare
Shew_0585 +1.8 3.3 cAMP-regulatory protein (RefSeq) compare
Shew_1528 +1.7 3.5 OmpA domain-containing protein (RefSeq) compare
Shew_2907 +1.7 1.9 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_1185 glyA +1.7 6.2 serine hydroxymethyltransferase (RefSeq) compare
Shew_2414 +1.6 1.2 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_3224 +1.6 4.2 hypothetical protein (RefSeq) compare
Shew_1644 +1.6 1.7 DSBA oxidoreductase (RefSeq) compare
Shew_0191 +1.5 1.3 cytochrome c, class I (RefSeq) compare
Shew_2950 +1.5 2.3 RluA family pseudouridine synthase (RefSeq) compare
Shew_0022 +1.5 11.4 TrkH family potassium uptake protein (RefSeq) compare
Shew_1011 +1.5 5.5 citrate transporter (RefSeq) compare
Shew_2906 +1.5 1.3 hypothetical protein (RefSeq) compare
Shew_1673 fabG +1.5 2.3 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_3197 +1.5 1.0 hypothetical protein (RefSeq) compare
Shew_3681 +1.5 5.5 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0216 +1.5 1.5 DNA adenine methylase (RefSeq) compare
Shew_2814 deoA +1.5 3.8 thymidine phosphorylase (RefSeq) compare
Shew_2087 +1.5 3.4 hypothetical protein (RefSeq) compare
Shew_1145 +1.5 2.2 translation initiation factor Sui1 (RefSeq) compare
Shew_3548 +1.4 1.0 hypothetical protein (RefSeq) compare
Shew_3395 +1.4 1.4 radical SAM domain-containing protein (RefSeq) compare
Shew_2086 +1.4 1.6 hypothetical protein (RefSeq) compare
Shew_1926 +1.4 2.9 transketolase, central region (RefSeq) compare
Shew_1439 +1.4 7.6 maleylacetoacetate isomerase (RefSeq) compare
Shew_3099 +1.4 1.5 TetR family transcriptional regulator (RefSeq) compare
Shew_0615 +1.3 7.8 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_3682 +1.3 7.7 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1092 +1.3 5.7 amino acid carrier protein (RefSeq) compare
Shew_0584 +1.3 1.3 hypothetical protein (RefSeq) compare
Shew_2919 +1.3 2.5 translation-associated GTPase (RefSeq) compare
Shew_1559 +1.3 1.0 hypothetical protein (RefSeq) compare
Shew_3316 +1.3 9.4 magnesium transporter (RefSeq) compare
Shew_2241 +1.3 2.8 hypothetical protein (RefSeq) compare
Shew_3568 +1.3 6.5 cation diffusion facilitator family transporter (RefSeq) compare
Shew_1594 +1.3 4.7 RluA family pseudouridine synthase (RefSeq) compare
Shew_2121 +1.3 1.6 diguanylate cyclase (RefSeq) compare
Shew_1951 +1.3 4.1 aromatic amino acid aminotransferase (RefSeq) compare
Shew_1524 +1.2 2.5 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_1732 +1.2 3.1 hypothetical protein (RefSeq) compare
Shew_1809 +1.2 7.4 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_0580 +1.2 2.1 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_2141 +1.2 3.2 lytic murein transglycosylase (RefSeq) compare
Shew_3385 uvrD +1.2 4.7 DNA-dependent helicase II (RefSeq) compare
Shew_2976 +1.2 1.4 hypothetical protein (RefSeq) compare
Shew_0268 +1.2 1.0 transcriptional antiterminator, Rof (RefSeq) compare
Shew_2409 +1.2 2.5 short chain dehydrogenase (RefSeq) compare
Shew_1122 +1.2 5.7 hypothetical protein (RefSeq) compare
Shew_1714 +1.2 3.0 alpha/beta hydrolase fold (RefSeq) compare
Shew_2025 +1.2 4.2 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_0469 +1.2 0.8 pentapeptide repeat-containing protein (RefSeq) compare
Shew_1050 +1.2 4.8 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_1927 +1.1 1.6 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0127 +1.1 3.1 LexA repressor (RefSeq) compare
Shew_1411 +1.1 5.9 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_1577 +1.1 1.0 aminotransferase, class IV (RefSeq) compare
Shew_2476 +1.1 1.9 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_1052 +1.1 2.3 GTP-binding protein LepA (RefSeq) compare
Shew_3727 +1.1 2.9 shikimate 5-dehydrogenase (RefSeq) compare
Shew_3062 +1.1 7.5 glycine dehydrogenase (RefSeq) compare
Shew_2667 +1.1 4.0 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_3664 +1.1 7.1 alpha-L-glutamate ligase (RefSeq) compare
Shew_2146 +1.1 3.4 hypothetical protein (RefSeq) compare
Shew_1189 +1.1 7.1 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_1925 +1.1 4.0 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_1037 +1.0 4.4 DNA mismatch repair protein (RefSeq) compare
Shew_0438 +1.0 1.0 GumN family protein (RefSeq) compare
Shew_2820 prfC +1.0 1.1 peptide chain release factor 3 (RefSeq) compare
Shew_1025 +1.0 0.9 hypothetical protein (RefSeq) compare
Shew_0495 +1.0 1.1 hypothetical protein (RefSeq) compare
Shew_0342 +1.0 4.4 hypothetical protein (RefSeq) compare
Shew_2570 +1.0 8.2 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1188 +1.0 2.9 riboflavin synthase subunit alpha (RefSeq) compare
Shew_3374 +1.0 2.4 hypothetical protein (RefSeq) compare
Shew_0214 +1.0 2.4 3-dehydroquinate synthase (RefSeq) compare
Shew_3262 +1.0 0.8 hypothetical protein (RefSeq) compare
Shew_2504 +1.0 1.6 PpiC-type peptidyl-prolyl cis-trans isomerase (RefSeq) compare
Shew_2246 +1.0 2.3 pseudouridine synthase (RefSeq) compare
Shew_3716 +1.0 2.8 cytochrome c, class I (RefSeq) compare
Shew_0430 +1.0 2.1 histone family protein DNA-binding protein (RefSeq) compare
Shew_0799 +1.0 1.4 MarR family transcriptional regulator (RefSeq) compare
Shew_3064 gcvT +1.0 5.3 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_1785 +1.0 0.9 band 7 protein (RefSeq) compare
Shew_2361 +1.0 1.0 proline racemase (RefSeq) compare
Shew_2958 +0.9 1.7 hypothetical protein (RefSeq) compare
Shew_3312 +0.9 2.6 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_0462 +0.9 0.6 hypothetical protein (RefSeq) compare
Shew_1407 +0.9 3.7 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_0320 +0.9 4.9 frataxin family protein (RefSeq) compare
Shew_1078 +0.9 4.9 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_3628 +0.9 0.8 MgtC/SapB transporter (RefSeq) compare
Shew_2554 +0.9 1.4 outer membrane protein W (RefSeq) compare
Shew_3556 +0.9 1.0 aminotransferase, class V (RefSeq) compare
Shew_1978 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_1209 +0.9 2.2 pseudouridylate synthase (RefSeq) compare
Shew_1289 +0.9 3.1 hypothetical protein (RefSeq) compare
Shew_1796 +0.9 1.5 hypothetical protein (RefSeq) compare
Shew_0324 +0.9 0.7 hypothetical protein (RefSeq) compare
Shew_1273 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_1214 +0.9 4.3 DNA mismatch repair protein (RefSeq) compare
Shew_1981 +0.9 2.1 AraC family transcriptional regulator (RefSeq) compare
Shew_2337 tgt +0.9 3.4 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_3622 hslO +0.9 4.9 Hsp33-like chaperonin (RefSeq) compare
Shew_0564 +0.9 5.8 DNA mismatch repair protein MutL (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress 5-Hydroxymethylfurfural in Shewanella loihica PV-4

For stress 5-Hydroxymethylfurfural across organisms