Experiment set4IT028 for Rhodospirillum rubrum S1H

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L-Malic Acid acid carbon source with ammonium chloride; no light

200 most important genes:

  gene name fitness t score description  
Rru_A0058 -3.2 -3.1 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A3190 -2.9 -3.4 Aspartate carbamoyltransferase (NCBI) compare
Rru_A1620 -2.8 -4.8 hypothetical protein (NCBI) compare
Rru_A2885 -2.5 -13.6 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A0469 -2.5 -12.3 Ketol-acid reductoisomerase (NCBI) compare
Rru_A0432 -2.5 -10.6 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A0467 -2.5 -11.5 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A3428 -2.5 -12.3 Tryptophan synthase (NCBI) compare
Rru_A2886 -2.4 -16.5 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A1105 -2.4 -5.0 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A3427 -2.4 -15.0 Tryptophan synthase, beta chain (NCBI) compare
Rru_A3267 -2.4 -7.2 Methionine biosynthesis MetW (NCBI) compare
Rru_A3276 -2.4 -3.6 Ornithine carbamoyltransferase (NCBI) compare
Rru_A1530 -2.4 -18.5 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A1897 -2.3 -6.1 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A3594 -2.3 -6.0 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A1854 -2.2 -7.5 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A3165 -2.2 -4.7 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A2771 -2.2 -5.1 Histidinol dehydrogenase (NCBI) compare
Rru_A3214 -2.2 -9.9 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A3751 -2.2 -8.2 Argininosuccinate synthase (NCBI) compare
Rru_A0468 -2.1 -3.4 Acetolactate synthase, small subunit (NCBI) compare
Rru_A3380 -2.1 -3.1 hypothetical protein (NCBI) compare
Rru_A3162 -2.1 -10.8 Prephenate dehydratase (NCBI) compare
Rru_A1827 -2.1 -10.0 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A1189 -2.0 -10.1 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A0296 -2.0 -2.4 hypothetical protein (NCBI) compare
Rru_A3571 -1.9 -3.9 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A3596 -1.9 -4.5 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A1593 -1.9 -8.7 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A3552 -1.9 -1.7 hypothetical protein (NCBI) compare
Rru_A1928 -1.9 -8.5 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A3277 -1.9 -4.7 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1675 -1.9 -9.1 Cytochrome c assembly protein (NCBI) compare
Rru_A0644 -1.8 -6.6 hypothetical protein (NCBI) compare
Rru_A1798 -1.8 -9.6 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A2772 -1.7 -2.4 ATP phosphoribosyltransferase (NCBI) compare
Rru_A1786 -1.7 -11.3 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A2377 -1.7 -0.4 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A1718 -1.7 -11.6 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) compare
Rru_A3266 -1.7 -7.4 Homoserine O-acetyltransferase (NCBI) compare
Rru_A1239 -1.7 -2.0 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A1444 -1.7 -6.3 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A1896 -1.6 -3.5 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A3202 -1.6 -12.5 DNA topoisomerase (NCBI) compare
Rru_A1435 -1.6 -5.9 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A1445 -1.5 -6.7 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A1883 -1.4 -2.7 Magnesium and cobalt transport protein CorA (NCBI) compare
Rru_B0039 -1.4 -11.6 Type I secretion system ATPase, PrtD (NCBI) compare
Rru_A2507 -1.4 -9.6 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A0514 -1.4 -7.5 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_B0037 -1.3 -12.4 Hemolysin-type calcium-binding region (NCBI) compare
Rru_A1436 -1.3 -5.3 Histidine Kinase (NCBI) compare
Rru_A2936 -1.3 -5.7 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1191 -1.3 -5.7 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A0667 -1.3 -5.7 Nicotinate-nucleotide-dimethylbenzimidazolephosphoribosyltransferase (NCBI) compare
Rru_B0040 -1.3 -11.3 Type I secretion membrane fusion protein, HlyD (NCBI) compare
Rru_A3642 -1.3 -1.9 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A3191 -1.2 -7.5 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A0159 -1.2 -1.5 Exodeoxyribonuclease VII (NCBI) compare
Rru_A3424 -1.2 -2.5 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A1308 -1.2 -8.2 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A3264 -1.2 -4.6 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A2201 -1.2 -3.6 Peptidase S1C, Do (NCBI) compare
Rru_A2715 -1.1 -7.8 Acyltransferase 3 (NCBI) compare
Rru_A1865 -1.1 -4.5 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A3378 -1.1 -4.3 hypothetical protein (NCBI) compare
Rru_B0043 -1.1 -3.8 hypothetical protein (NCBI) compare
Rru_A1014 -1.1 -1.9 hypothetical protein (NCBI) compare
Rru_A0117 -1.1 -0.4 ABC transporter component (NCBI) compare
Rru_A1021 -1.1 -3.5 Sigma 32 (RpoH) (NCBI) compare
Rru_A2500 -1.1 -0.2 Rhodanese-like (NCBI) compare
Rru_B0049 -1.1 -0.3 dTDP-4-dehydrorhamnose reductase (NCBI) compare
Rru_A1309 -1.1 -6.0 acetoacetyl-CoA reductase (NCBI) compare
Rru_A2184 -1.1 -0.3 Pyridoxamine 5'-phosphate oxidase-related, FMN-binding (NCBI) compare
Rru_A0574 -1.1 -3.6 Carboxylyase-related protein (NCBI) compare
Rru_A0397 -1.0 -3.5 Argininosuccinate lyase (NCBI) compare
Rru_A2562 -1.0 -3.4 CheW protein (NCBI) compare
Rru_A1085 -1.0 -1.6 Metallophosphoesterase (NCBI) compare
Rru_A3614 -1.0 -3.3 Maf-like protein (NCBI) compare
Rru_A1310 -1.0 -5.3 Acetyl-CoA C-acyltransferase (NCBI) compare
Rru_A1513 -1.0 -1.9 hypothetical protein (NCBI) compare
Rru_A3240 -1.0 -1.1 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A1839 -1.0 -3.0 TRAP-type C4-dicarboxylate transport system periplasmic component-like (NCBI) compare
Rru_A1767 -1.0 -0.5 peptidase M23B (NCBI) compare
Rru_A3023 -1.0 -5.1 hypothetical protein (NCBI) compare
Rru_A1019 -1.0 -2.3 FAD dependent oxidoreductase (NCBI) compare
Rru_A1111 -1.0 -5.1 Pseudouridine synthase, RluD (NCBI) compare
Rru_A1016 -0.9 -6.3 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3677 -0.9 -2.7 Tripartite ATP-independent periplasmic transporter, DctQ component (NCBI) compare
Rru_A1434 -0.9 -5.4 Quinolinate synthetase A (NCBI) compare
Rru_A2512 -0.9 -1.6 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A0643 -0.9 -4.2 Protein of unknown function DUF152 (NCBI) compare
Rru_A2908 -0.9 -3.8 Protein of unknown function DUF140 (NCBI) compare
Rru_A0661 -0.9 -2.3 Hly-III related proteins (NCBI) compare
Rru_A1814 -0.9 -1.1 Carbon monoxide dehydrogenase subunit G (NCBI) compare
Rru_A2549 -0.8 -3.1 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A3146 -0.8 -2.0 hypothetical protein (NCBI) compare
Rru_A3783 -0.8 -4.4 tRNA pseudouridine synthase B (NCBI) compare
Rru_A3532 -0.8 -3.7 UspA (NCBI) compare
Rru_A2190 -0.8 -1.8 TRm3 transposase (NCBI) compare
Rru_A0603 -0.8 -2.7 Two component Transcriptional regulator, Winged helix family (NCBI) compare
Rru_A0253 -0.8 -4.8 GDP-mannose 4,6-dehydratase (NCBI) compare
Rru_A3256 -0.8 -2.4 Protein of unknown function DUF218 (NCBI) compare
Rru_A2656 -0.8 -1.7 ATP12 ATPase (NCBI) compare
Rru_A2424 -0.8 -2.9 Gamma-glutamyltranspeptidase (NCBI) compare
Rru_A0097 -0.8 -3.0 Class I peptide chain release factor (NCBI) compare
Rru_B0042 -0.8 -2.8 hypothetical protein (NCBI) compare
Rru_A0585 -0.8 -1.4 ABC transporter component (NCBI) compare
Rru_A1015 -0.8 -1.9 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A1837 -0.8 -3.4 Porphobilinogen synthase (NCBI) compare
Rru_A0010 -0.8 -1.9 Sigma-54 (RpoN) (NCBI) compare
Rru_A3739 -0.8 -1.9 hypothetical protein (NCBI) compare
Rru_A1911 -0.7 -1.6 Ferric uptake regulator (FUR) family (NCBI) compare
Rru_A2411 -0.7 -4.6 Aminotransferase, class I and II (NCBI) compare
Rru_A0607 -0.7 -0.3 Adenine phosphoribosyl transferase (NCBI) compare
Rru_A1018 -0.7 -4.9 extracellular solute-binding protein, family 1 (NCBI) compare
Rru_A3035 -0.7 -3.7 nuclease (SNase-like) (NCBI) compare
Rru_A2161 -0.7 -6.2 Polyphosphate kinase (NCBI) compare
Rru_A0023 -0.7 -0.2 hypothetical protein (NCBI) compare
Rru_A3627 -0.7 -3.0 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_B0005 -0.7 -1.6 Glycosyl transferase (NCBI) compare
Rru_A3186 -0.7 -1.4 hypothetical protein (NCBI) compare
Rru_A2538 -0.7 -2.2 hypothetical protein (NCBI) compare
Rru_A2911 -0.7 -5.0 ABC-type uncharacterized transport system auxiliary component-like (NCBI) compare
Rru_A0652 -0.7 -0.3 Pseudouridine synthase, Rsu (NCBI) compare
Rru_A0162 -0.7 -4.0 Chaperonin Cpn60/TCP-1 (NCBI) compare
Rru_A1138 -0.7 -2.7 ABC transporter component (NCBI) compare
Rru_A0329 -0.7 -1.7 hypothetical protein (NCBI) compare
Rru_A2800 -0.7 -2.2 hypothetical protein (NCBI) compare
Rru_A3548 -0.7 -5.4 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A2083 -0.7 -3.9 CreA (NCBI) compare
Rru_A1307 -0.7 -2.5 Thioesterase superfamily (NCBI) compare
Rru_A2503 -0.7 -4.2 Hydroxypyruvate isomerase (NCBI) compare
Rru_A1348 -0.7 -1.5 Protein of unknown function DUF81 (NCBI) compare
Rru_B0038 -0.7 -0.1 dTDP-4-dehydrorhamnose 3,5-epimerase (NCBI) compare
Rru_B0050 -0.7 -0.2 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A0556 -0.7 -4.5 Formyltetrahydrofolate deformylase (NCBI) compare
Rru_A1265 -0.6 -3.1 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1472 -0.6 -0.9 Acetate CoA-transferase (NCBI) compare
Rru_A2345 -0.6 -3.9 Glycosyl transferase, group 1 (NCBI) compare
Rru_A0852 -0.6 -3.2 hypothetical protein (NCBI) compare
Rru_A1855 -0.6 -3.8 hypothetical protein (NCBI) compare
Rru_A0477 -0.6 -1.5 hypothetical protein (NCBI) compare
Rru_A0207 -0.6 -0.8 Cobalt chelatase, CobT subunit (NCBI) compare
Rru_A2799 -0.6 -0.3 hypothetical protein (NCBI) compare
Rru_A0148 -0.6 -1.0 GTP-binding protein TypA (NCBI) compare
Rru_A2351 -0.6 -4.4 Macrocin-O-methyltransferase (NCBI) compare
Rru_A2603 -0.6 -2.2 Two Component Transcriptional Regulator, LuxR family (NCBI) compare
Rru_A0894 -0.6 -0.3 stress protein (NCBI) compare
Rru_A3755 -0.6 -4.1 Heat shock protein Hsp20 (NCBI) compare
Rru_A3544 -0.6 -1.6 Phosphate uptake regulator, PhoU (NCBI) compare
Rru_A1131 -0.6 -4.0 Aminotransferase, class IV (NCBI) compare
Rru_A1432 -0.6 -4.1 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A2347 -0.6 -4.6 hypothetical protein (NCBI) compare
Rru_A2497 -0.6 -2.4 Peptide chain release factor 3 (NCBI) compare
Rru_A1636 -0.6 -0.4 NADH-ubiquinone oxidoreductase, chain 4L (NCBI) compare
Rru_A0089 -0.6 -4.8 ATP-dependent DNA helicase RecQ (NCBI) compare
Rru_A2486 -0.6 -2.7 Glucokinase (NCBI) compare
Rru_A3621 -0.6 -1.5 Methylated-DNA-(protein)-cysteine S-methyltransferase (NCBI) compare
Rru_A0232 -0.6 -3.8 hypothetical protein (NCBI) compare
Rru_A2455 -0.6 -1.5 hypothetical protein (NCBI) compare
Rru_A0515 -0.6 -0.7 HAD-superfamily subfamily IIA hydrolase (NCBI) compare
Rru_A2614 -0.6 -0.2 Transcriptional Regulator, XRE family with Cupin sensor domain (NCBI) compare
Rru_A3139 -0.6 -3.4 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A3371 -0.6 -2.5 Zinc-containing alcohol dehydrogenase superfamily (NCBI) compare
Rru_A0406 -0.6 -1.9 DNA repair protein RadA (NCBI) compare
Rru_A1607 -0.5 -3.9 4-alpha-glucanotransferase (NCBI) compare
Rru_A1797 -0.5 -3.2 hypothetical protein (NCBI) compare
Rru_A0041 -0.5 -0.1 Cytochrome c, class II (NCBI) compare
Rru_A0391 -0.5 -1.7 hypothetical protein (NCBI) compare
Rru_A2110 -0.5 -3.2 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
Rru_A2483 -0.5 -4.0 5'-Nucleotidase (NCBI) compare
Rru_A0854 -0.5 -1.7 Sulfotransferase (NCBI) compare
Rru_A2324 -0.5 -2.8 PBS lyase HEAT-like repeat (NCBI) compare
Rru_A1437 -0.5 -2.4 Sodium:dicarboxylate symporter (NCBI) compare
Rru_B0033 -0.5 -4.1 hypothetical protein (NCBI) compare
Rru_A3003 -0.5 -1.7 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A1017 -0.5 -3.7 Spermidine/putrescine ABC transporter ATP-binding subunit (NCBI) compare
Rru_A1637 -0.5 -3.0 Na+/H+ antiporter MnhB subunit-related protein (NCBI) compare
Rru_A0024 -0.5 -2.0 peptidase (NCBI) compare
Rru_A0323 -0.5 -1.2 4Fe-4S ferredoxin, iron-sulfur binding (NCBI) compare
Rru_A3716 -0.5 -0.2 Polysaccharide export protein (NCBI) compare
Rru_A1916 -0.5 -1.8 Ferredoxin (NCBI) compare
Rru_A2348 -0.5 -3.6 Glycosyl transferase (NCBI) compare
Rru_A1408 -0.5 -2.6 chemotaxis sensory transducer (NCBI) compare
Rru_A2901 -0.5 -1.8 Histidine triad (HIT) protein (NCBI) compare
Rru_A0361 -0.5 -1.8 Methylthioadenosine phosphorylase (NCBI) compare
Rru_A2866 -0.5 -3.1 Ribosomal protein L11 methyltransferase (NCBI) compare
Rru_A1336 -0.5 -2.6 Periplasmic binding protein/LacI transcriptional regulator (NCBI) compare
Rru_A0657 -0.5 -1.8 Lysine exporter protein (LYSE/YGGA) (NCBI) compare
Rru_A0777 -0.5 -0.1 D-lactate dehydrogenase (cytochrome) (NCBI) compare
Rru_A0615 -0.5 -2.1 photosynthetic complex assembly protein (NCBI) compare
Rru_A0458 -0.5 -3.4 hypothetical protein (NCBI) compare
Rru_A2454 -0.5 -2.8 hypothetical protein (NCBI) compare
Rru_A2310 -0.5 -1.9 cytochrome c family protein (NCBI) compare
Rru_A3398 -0.5 -0.8 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A1414 -0.5 -1.9 regulatory protein GntR (NCBI) compare
Rru_A1334 -0.5 -2.1 Ribose 5-phosphate isomerase B (NCBI) compare
Rru_A3049 -0.5 -2.9 Glycine dehydrogenase (decarboxylating) (NCBI) compare


Specific Phenotypes

For 4 genes in this experiment

For anaerboic nitrogen source Ammonium chloride in Rhodospirillum rubrum S1H

For anaerboic nitrogen source Ammonium chloride across organisms