Experiment set4IT025 for Shewanella loihica PV-4

Compare to:

LB with Choline Lysine 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_3560 +5.2 34.8 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_3311 +5.1 30.8 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3561 +5.1 24.8 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_1298 guaA +4.8 39.3 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_0296 +4.8 7.1 heat shock protein Hsp20 (RefSeq) compare
Shew_2637 +4.7 28.6 PII uridylyl-transferase (RefSeq) compare
Shew_0755 +4.3 15.4 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_3554 glnA +4.2 8.0 glutamine synthetase (RefSeq) compare
Shew_3273 +3.8 22.2 hypothetical protein (RefSeq) compare
Shew_2572 +3.8 17.5 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1301 +3.7 31.1 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_1224 +3.7 28.2 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1819 +3.4 11.2 GntR family transcriptional regulator (RefSeq) compare
Shew_2498 +3.3 5.6 extracellular solute-binding protein (RefSeq) compare
Shew_2382 +3.3 22.9 cysteine synthase A (RefSeq) compare
Shew_3488 +3.3 6.0 ribonuclease PH (RefSeq) compare
Shew_2502 +3.3 12.3 ABC transporter-related protein (RefSeq) compare
Shew_3412 purH +3.3 19.2 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_0867 +3.2 5.3 malate dehydrogenase (RefSeq) compare
Shew_3487 pyrE +3.1 17.2 orotate phosphoribosyltransferase (RefSeq) compare
Shew_0728 +3.1 24.7 dihydroorotase (RefSeq) compare
Shew_1013 +3.1 22.8 aspartate carbamoyltransferase (RefSeq) compare
Shew_0330 +3.0 2.4 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_0618 +3.0 6.3 hypothetical protein (RefSeq) compare
Shew_1425 +3.0 12.0 adenylyl-sulfate kinase (RefSeq) compare
Shew_1512 +2.9 14.2 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_3377 +2.8 3.2 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_2320 +2.7 17.0 RNA methyltransferase (RefSeq) compare
Shew_2302 +2.7 13.5 amidophosphoribosyltransferase (RefSeq) compare
Shew_1810 +2.6 8.9 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1341 +2.6 7.7 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_2000 +2.6 6.4 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_3378 +2.6 5.8 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_3413 +2.6 20.3 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_1128 +2.6 21.4 LysR family transcriptional regulator (RefSeq) compare
Shew_2049 +2.6 14.6 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_1602 +2.6 7.5 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_1809 +2.5 20.2 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_1011 +2.5 13.7 citrate transporter (RefSeq) compare
Shew_3710 tdh +2.4 17.5 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_3621 +2.4 2.3 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_1563 +2.4 16.6 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_2476 +2.4 6.5 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_3709 +2.3 15.5 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_2473 +2.3 6.3 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_0193 +2.2 6.8 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_2838 carB +2.2 13.0 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_2481 +2.2 12.3 porin (RefSeq) compare
Shew_1230 +2.1 4.2 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_2839 +2.1 15.7 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_1657 sucC +2.1 4.2 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_1186 +2.1 3.4 transcriptional regulator NrdR (RefSeq) compare
Shew_2812 deoD +2.1 7.5 purine nucleoside phosphorylase (RefSeq) compare
Shew_3499 +2.0 9.2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_1673 fabG +2.0 4.2 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2211 +2.0 6.0 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_0421 +2.0 1.2 phage shock protein C, PspC (RefSeq) compare
Shew_2571 +2.0 14.2 propionyl-CoA carboxylase (RefSeq) compare
Shew_3295 +1.9 12.6 AFG1 family ATPase (RefSeq) compare
Shew_2919 +1.9 5.7 translation-associated GTPase (RefSeq) compare
Shew_0570 +1.9 3.3 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_3622 hslO +1.9 13.6 Hsp33-like chaperonin (RefSeq) compare
Shew_2584 +1.9 13.6 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_1302 +1.8 6.9 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_0571 +1.8 5.4 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_0359 fre +1.8 11.6 FMN reductase (RefSeq) compare
Shew_2409 +1.8 3.4 short chain dehydrogenase (RefSeq) compare
Shew_2573 +1.8 14.4 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_0086 +1.8 14.5 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_1287 +1.8 5.1 hypothetical protein (RefSeq) compare
Shew_1990 +1.7 5.4 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_0320 +1.7 9.1 frataxin family protein (RefSeq) compare
Shew_0534 +1.7 4.7 major facilitator transporter (RefSeq) compare
Shew_1559 +1.7 1.8 hypothetical protein (RefSeq) compare
Shew_0613 +1.7 6.4 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_1050 +1.7 9.4 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_1092 +1.7 11.1 amino acid carrier protein (RefSeq) compare
Shew_2434 +1.7 2.9 hypothetical protein (RefSeq) compare
Shew_1601 +1.6 2.9 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_0614 +1.6 7.6 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_2008 +1.6 1.3 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1210 +1.6 5.7 stationary-phase survival protein SurE (RefSeq) compare
Shew_3189 +1.6 4.1 hypothetical protein (RefSeq) compare
Shew_1992 +1.6 8.3 hypothetical protein (RefSeq) compare
Shew_1951 +1.6 5.6 aromatic amino acid aminotransferase (RefSeq) compare
Shew_1437 +1.6 11.1 transcriptional regulator, TyrR (RefSeq) compare
Shew_2558 +1.6 1.7 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_3225 +1.5 7.1 glutathione synthetase (RefSeq) compare
Shew_3500 +1.5 3.6 putative endoribonuclease L-PSP (RefSeq) compare
Shew_1189 +1.5 10.2 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_2814 deoA +1.5 5.5 thymidine phosphorylase (RefSeq) compare
Shew_1185 glyA +1.5 4.6 serine hydroxymethyltransferase (RefSeq) compare
Shew_1438 +1.5 4.8 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_2414 +1.4 1.4 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_3065 +1.4 10.5 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_1625 +1.4 3.7 L-serine dehydratase 1 (RefSeq) compare
Shew_3431 aceE +1.3 10.0 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_3568 +1.3 7.5 cation diffusion facilitator family transporter (RefSeq) compare
Shew_0191 +1.3 2.3 cytochrome c, class I (RefSeq) compare
Shew_0763 +1.3 7.0 putative PAS/PAC sensor protein (RefSeq) compare
Shew_1188 +1.3 4.3 riboflavin synthase subunit alpha (RefSeq) compare
Shew_1439 +1.3 8.8 maleylacetoacetate isomerase (RefSeq) compare
Shew_1397 +1.3 4.2 amino acid/peptide transporter (RefSeq) compare
Shew_2025 +1.3 6.4 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_2813 +1.3 2.7 phosphopentomutase (RefSeq) compare
Shew_0585 +1.2 3.4 cAMP-regulatory protein (RefSeq) compare
Shew_1925 +1.2 5.5 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_3759 +1.2 8.8 imidazolonepropionase (RefSeq) compare
Shew_1987 +1.2 4.8 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_0799 +1.2 2.4 MarR family transcriptional regulator (RefSeq) compare
Shew_0022 +1.2 7.6 TrkH family potassium uptake protein (RefSeq) compare
Shew_2770 +1.2 1.0 polyprenyl synthetase (RefSeq) compare
Shew_3681 +1.2 5.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0220 +1.2 4.0 phosphoglycolate phosphatase (RefSeq) compare
Shew_1859 +1.2 1.4 carbonate dehydratase (RefSeq) compare
Shew_2087 +1.2 3.3 hypothetical protein (RefSeq) compare
Shew_1926 +1.2 2.9 transketolase, central region (RefSeq) compare
Shew_3432 pdhR +1.2 3.5 transcriptional regulator PdhR (RefSeq) compare
Shew_1820 prpB +1.1 2.2 2-methylisocitrate lyase (RefSeq) compare
Shew_0127 +1.1 3.2 LexA repressor (RefSeq) compare
Shew_3312 +1.1 4.2 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_2962 +1.1 3.1 malate dehydrogenase (RefSeq) compare
Shew_2837 +1.1 1.0 transcription elongation factor GreA (RefSeq) compare
Shew_3197 +1.1 1.1 hypothetical protein (RefSeq) compare
Shew_2061 +1.1 2.9 radical SAM domain-containing protein (RefSeq) compare
Shew_2976 +1.0 1.4 hypothetical protein (RefSeq) compare
Shew_1927 +1.0 1.4 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0580 +1.0 1.9 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_0615 +1.0 6.5 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_1985 +1.0 3.5 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_0995 +1.0 3.8 phage integrase family protein (RefSeq) compare
Shew_0540 +1.0 2.0 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_0342 +1.0 5.2 hypothetical protein (RefSeq) compare
Shew_3062 +1.0 8.3 glycine dehydrogenase (RefSeq) compare
Shew_2013 +1.0 1.6 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_3374 +1.0 3.7 hypothetical protein (RefSeq) compare
Shew_3271 +1.0 5.3 galactokinase (RefSeq) compare
Shew_2074 +1.0 3.0 TonB-dependent receptor (RefSeq) compare
Shew_0268 +1.0 0.9 transcriptional antiterminator, Rof (RefSeq) compare
Shew_3682 +1.0 6.9 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_3548 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_3316 +0.9 5.5 magnesium transporter (RefSeq) compare
Shew_0462 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_2509 tig +0.9 3.7 trigger factor (RefSeq) compare
Shew_1867 +0.9 3.8 hypothetical protein (RefSeq) compare
Shew_2285 +0.9 0.8 UDP-glucose 4-epimerase (RefSeq) compare
Shew_3711 +0.9 0.7 rhodanese domain-containing protein (RefSeq) compare
Shew_2415 +0.9 1.9 major facilitator transporter (RefSeq) compare
Shew_3430 +0.9 1.5 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_3556 +0.9 1.4 aminotransferase, class V (RefSeq) compare
Shew_1372 fliL +0.8 2.7 flagellar basal body-associated protein FliL (RefSeq) compare
Shew_2241 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1920 +0.8 3.5 alpha/beta hydrolase fold (RefSeq) compare
Shew_3628 +0.8 0.8 MgtC/SapB transporter (RefSeq) compare
Shew_1935 +0.8 2.6 hypothetical protein (RefSeq) compare
Shew_2361 +0.8 1.1 proline racemase (RefSeq) compare
Shew_1907 +0.8 3.3 glutathione-dependent formaldehyde-activating, GFA (RefSeq) compare
Shew_2537 +0.8 1.6 AraC family transcriptional regulator (RefSeq) compare
Shew_0430 +0.8 2.3 histone family protein DNA-binding protein (RefSeq) compare
Shew_1090 +0.8 1.0 OmpA/MotB domain-containing protein (RefSeq) compare
Shew_0548 +0.8 3.7 yqiA-like hydrolase, affects the cell envelope (from data) compare
Shew_3498 rpoZ +0.8 2.0 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1785 +0.8 1.0 band 7 protein (RefSeq) compare
Shew_0410 +0.8 3.7 peptidase U62, modulator of DNA gyrase (RefSeq) compare
Shew_3395 +0.8 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_1209 +0.8 2.2 pseudouridylate synthase (RefSeq) compare
Shew_3313 +0.8 1.8 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shew_3064 gcvT +0.8 5.7 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_2820 prfC +0.8 0.9 peptide chain release factor 3 (RefSeq) compare
Shew_1594 +0.8 3.5 RluA family pseudouridine synthase (RefSeq) compare
Shew_2105 +0.8 1.0 methylated-DNA-(protein)-cysteine S-methyltransferase (RefSeq) compare
Shew_1122 +0.8 3.7 hypothetical protein (RefSeq) compare
Shew_1479 +0.8 1.5 deoxyribodipyrimidine photo-lyase (RefSeq) compare
Shew_0192 +0.8 2.8 TPR repeat-containing protein (RefSeq) compare
Shew_0942 +0.7 4.9 RDD domain-containing protein (RefSeq) compare
Shew_2570 +0.7 5.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1865 +0.7 4.7 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_3664 +0.7 4.3 alpha-L-glutamate ligase (RefSeq) compare
Shew_2033 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_2086 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_1574 +0.7 3.1 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_1667 +0.7 2.3 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_1473 +0.7 3.1 hypothetical protein (RefSeq) compare
Shew_3687 +0.7 4.0 molybdopterin-guanine dinucleotide biosynthesis protein B (RefSeq) compare
Shew_R0033 +0.7 1.5 tRNA-Arg (RefSeq) compare
Shew_1822 +0.7 2.7 aconitate hydratase (RefSeq) compare
Shew_3569 +0.7 1.7 protein of unknown function, Spy-related (RefSeq) compare
Shew_1402 +0.7 4.5 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_1889 +0.7 4.7 alpha amylase, catalytic region (RefSeq) compare
Shew_0417 +0.7 0.9 ArsR family transcriptional regulator (RefSeq) compare
Shew_1264 +0.7 1.4 UvrD/REP helicase (RefSeq) compare
Shew_0992 +0.7 2.0 BsuBIPstI restriction endonuclease domain-containing protein (RefSeq) compare
Shew_1833 +0.7 1.5 putative serine protein kinase, PrkA (RefSeq) compare
Shew_1555 +0.7 1.4 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_1839 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_3029 +0.7 2.3 hypothetical protein (RefSeq) compare
Shew_3131 +0.7 4.8 poly(A) polymerase (RefSeq) compare
Shew_1577 +0.7 0.8 aminotransferase, class IV (RefSeq) compare
Shew_1110 +0.7 3.0 nitrogen regulatory protein P-II (RefSeq) compare
Shew_0529 +0.7 1.3 Sel1 domain-containing protein (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Choline Lysine in Shewanella loihica PV-4

For stress Choline Lysine across organisms