Experiment set4IT024 for Shewanella loihica PV-4

Compare to:

LB with 1-ethyl-3-methylimidazolium chloride 50 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_3560 +3.9 26.2 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_3561 +3.7 20.9 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_2049 +3.4 20.3 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_2637 +3.4 19.5 PII uridylyl-transferase (RefSeq) compare
Shew_3311 +3.4 17.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3554 glnA +3.3 7.6 glutamine synthetase (RefSeq) compare
Shew_1301 +2.9 21.1 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_0618 +2.8 6.3 hypothetical protein (RefSeq) compare
Shew_1512 +2.8 13.2 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_0459 +2.8 10.7 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_1128 +2.8 19.3 LysR family transcriptional regulator (RefSeq) compare
Shew_3413 +2.8 21.1 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_3488 +2.7 7.5 ribonuclease PH (RefSeq) compare
Shew_2302 +2.7 18.4 amidophosphoribosyltransferase (RefSeq) compare
Shew_1822 +2.7 11.8 aconitate hydratase (RefSeq) compare
Shew_1298 guaA +2.7 20.1 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1819 +2.6 9.0 GntR family transcriptional regulator (RefSeq) compare
Shew_0763 +2.5 9.7 putative PAS/PAC sensor protein (RefSeq) compare
Shew_0296 +2.5 3.5 heat shock protein Hsp20 (RefSeq) compare
Shew_1224 +2.5 20.9 sodium:dicarboxylate symporter (RefSeq) compare
Shew_0777 +2.5 3.6 two-component response regulator (RefSeq) compare
Shew_2572 +2.4 12.8 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_3412 purH +2.4 16.4 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_1013 +2.3 18.9 aspartate carbamoyltransferase (RefSeq) compare
Shew_3378 +2.1 5.3 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_2481 +2.0 13.6 porin (RefSeq) compare
Shew_3487 pyrE +1.9 7.3 orotate phosphoribosyltransferase (RefSeq) compare
Shew_0867 +1.9 3.1 malate dehydrogenase (RefSeq) compare
Shew_1823 +1.9 5.1 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_0330 +1.9 1.4 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_3431 aceE +1.8 14.8 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_0950 +1.8 7.1 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2838 carB +1.7 15.3 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_1341 +1.7 4.9 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3432 pdhR +1.7 3.6 transcriptional regulator PdhR (RefSeq) compare
Shew_1186 +1.7 2.8 transcriptional regulator NrdR (RefSeq) compare
Shew_1230 +1.7 9.2 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_2008 +1.6 2.1 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_0755 +1.6 5.6 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_2571 +1.6 11.9 propionyl-CoA carboxylase (RefSeq) compare
Shew_2410 +1.6 1.2 beta-ketoacyl synthase (RefSeq) compare
Shew_2211 +1.6 4.1 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_1210 +1.6 4.4 stationary-phase survival protein SurE (RefSeq) compare
Shew_3189 +1.6 4.6 hypothetical protein (RefSeq) compare
Shew_3691 +1.5 2.0 hypothetical protein (RefSeq) compare
Shew_2839 +1.5 12.3 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_3377 +1.5 1.6 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_2382 +1.5 9.8 cysteine synthase A (RefSeq) compare
Shew_2812 deoD +1.4 6.5 purine nucleoside phosphorylase (RefSeq) compare
Shew_2573 +1.4 11.7 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_2320 +1.4 8.6 RNA methyltransferase (RefSeq) compare
Shew_1859 +1.4 1.8 carbonate dehydratase (RefSeq) compare
Shew_1185 glyA +1.4 6.6 serine hydroxymethyltransferase (RefSeq) compare
Shew_1302 +1.4 6.9 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_3621 +1.4 1.2 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_3499 +1.4 4.3 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_3710 tdh +1.3 11.2 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1620 +1.3 5.4 adenosylmethionine decarboxylase (RefSeq) compare
Shew_0585 +1.3 3.8 cAMP-regulatory protein (RefSeq) compare
Shew_3708 +1.3 8.1 TetR family transcriptional regulator (RefSeq) compare
Shew_3273 +1.3 6.2 hypothetical protein (RefSeq) compare
Shew_2228 +1.3 8.5 inosine kinase (RefSeq) compare
Shew_1922 +1.3 4.5 phosphoglucomutase (RefSeq) compare
Shew_1092 +1.2 8.6 amino acid carrier protein (RefSeq) compare
Shew_3316 +1.2 9.9 magnesium transporter (RefSeq) compare
Shew_3709 +1.2 8.3 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_0320 +1.2 8.9 frataxin family protein (RefSeq) compare
Shew_1559 +1.2 1.3 hypothetical protein (RefSeq) compare
Shew_0086 +1.2 9.9 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_3430 +1.2 2.0 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0421 +1.2 1.0 phage shock protein C, PspC (RefSeq) compare
Shew_1425 +1.2 5.6 adenylyl-sulfate kinase (RefSeq) compare
Shew_2584 +1.2 8.3 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_2435 +1.2 7.1 sodium/proline symporter (RefSeq) compare
Shew_1050 +1.2 5.0 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_2558 +1.2 1.8 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_1931 +1.2 1.8 alkylphosphonate utilization operon protein PhnA (RefSeq) compare
Shew_1820 prpB +1.1 1.8 2-methylisocitrate lyase (RefSeq) compare
Shew_0728 +1.1 7.4 dihydroorotase (RefSeq) compare
Shew_3718 +1.1 1.6 hypothetical protein (RefSeq) compare
Shew_0407 +1.1 4.6 ribonuclease G (RefSeq) compare
Shew_1439 +1.1 5.8 maleylacetoacetate isomerase (RefSeq) compare
Shew_1438 +1.1 3.7 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_1402 +1.0 7.1 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_1673 fabG +1.0 1.9 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2000 +0.9 2.0 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_0462 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_2414 +0.9 1.2 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_1078 +0.9 6.8 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_2285 +0.9 1.1 UDP-glucose 4-epimerase (RefSeq) compare
Shew_0613 +0.9 4.1 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_1073 +0.9 1.4 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_0191 +0.9 1.3 cytochrome c, class I (RefSeq) compare
Shew_2347 +0.9 2.3 phosphonate ABC transporter, periplasmic phosphonate-binding protein (RefSeq) compare
Shew_0799 +0.9 1.8 MarR family transcriptional regulator (RefSeq) compare
Shew_1264 +0.8 1.8 UvrD/REP helicase (RefSeq) compare
Shew_0446 +0.8 1.2 hypothetical protein (RefSeq) compare
Shew_1287 +0.8 2.3 hypothetical protein (RefSeq) compare
Shew_2264 +0.8 1.9 hypothetical protein (RefSeq) compare
Shew_2919 +0.8 2.2 translation-associated GTPase (RefSeq) compare
Shew_3295 +0.8 5.7 AFG1 family ATPase (RefSeq) compare
Shew_0580 +0.8 1.8 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_0866 +0.8 0.8 arginine repressor (RefSeq) compare
Shew_2504 +0.8 1.6 PpiC-type peptidyl-prolyl cis-trans isomerase (RefSeq) compare
Shew_0359 fre +0.8 5.1 FMN reductase (RefSeq) compare
Shew_3197 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_1209 +0.7 2.3 pseudouridylate synthase (RefSeq) compare
Shew_0722 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_3622 hslO +0.7 5.0 Hsp33-like chaperonin (RefSeq) compare
Shew_3062 +0.7 6.0 glycine dehydrogenase (RefSeq) compare
Shew_1810 +0.7 3.0 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_R0033 +0.7 1.7 tRNA-Arg (RefSeq) compare
Shew_0342 +0.7 5.5 hypothetical protein (RefSeq) compare
Shew_0615 +0.7 4.2 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_1574 +0.7 3.3 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_0627 +0.7 4.8 hypothetical protein (RefSeq) compare
Shew_0828 +0.7 0.8 LysR family transcriptional regulator (RefSeq) compare
Shew_3267 +0.7 3.8 sodium/hydrogen exchanger (RefSeq) compare
Shew_0614 +0.7 2.7 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_0374 hslU +0.7 3.6 ATP-dependent protease ATP-binding subunit (RefSeq) compare
Shew_1839 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_3711 +0.7 0.6 rhodanese domain-containing protein (RefSeq) compare
Shew_3681 +0.7 3.7 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3481 +0.7 2.7 DNA repair protein RadC (RefSeq) compare
Shew_0268 +0.7 1.3 transcriptional antiterminator, Rof (RefSeq) compare
Shew_3395 +0.7 1.0 radical SAM domain-containing protein (RefSeq) compare
Shew_1785 +0.7 1.1 band 7 protein (RefSeq) compare
Shew_1594 +0.7 2.5 RluA family pseudouridine synthase (RefSeq) compare
Shew_1867 +0.7 2.7 hypothetical protein (RefSeq) compare
Shew_1289 +0.7 3.1 hypothetical protein (RefSeq) compare
Shew_2887 +0.7 1.7 sterol desaturase family protein (RefSeq) compare
Shew_1555 +0.6 1.3 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_1881 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_0889 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_0480 +0.6 1.0 Sel1 domain-containing protein (RefSeq) compare
Shew_3568 +0.6 2.9 cation diffusion facilitator family transporter (RefSeq) compare
Shew_2837 +0.6 0.6 transcription elongation factor GreA (RefSeq) compare
Shew_0127 +0.6 1.6 LexA repressor (RefSeq) compare
Shew_2648 +0.6 1.2 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_3500 +0.6 1.6 putative endoribonuclease L-PSP (RefSeq) compare
Shew_0316 +0.6 4.4 protein of unknown function DUF513, hemX (RefSeq) compare
Shew_1667 +0.6 2.2 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_0047 +0.6 2.7 molybdopterin biosynthesis protein MoeB (RefSeq) compare
Shew_2352 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_1806 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_1025 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_1400 +0.6 1.2 lipopolysaccharide biosynthesis protein (RefSeq) compare
Shew_2241 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_1937 +0.6 2.5 peptidase M14, carboxypeptidase A (RefSeq) compare
Shew_2652 +0.6 2.4 hypothetical protein (RefSeq) compare
Shew_2385 +0.6 3.3 TonB-dependent receptor, plug (RefSeq) compare
Shew_1488 +0.6 1.7 FAD linked oxidase domain-containing protein (RefSeq) compare
Shew_3628 +0.6 0.6 MgtC/SapB transporter (RefSeq) compare
Shew_3064 gcvT +0.6 3.6 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_0775 +0.6 4.3 TetR family transcriptional regulator (RefSeq) compare
Shew_0833 +0.6 0.8 hypoxanthine-guanine phosphoribosyltransferase (RefSeq) compare
Shew_2561 +0.6 3.0 6-phosphogluconate dehydrogenase (RefSeq) compare
Shew_3598 +0.6 0.6 AsnC family transcriptional regulator (RefSeq) compare
Shew_3605 +0.6 0.9 cell division ATP-binding protein FtsE (RefSeq) compare
Shew_0625 +0.6 3.5 spermidine synthase (RefSeq) compare
Shew_1935 +0.6 2.4 hypothetical protein (RefSeq) compare
Shew_3556 +0.6 1.2 aminotransferase, class V (RefSeq) compare
Shew_1015 +0.6 2.5 Cl- channel, voltage-gated family protein (RefSeq) compare
Shew_2939 +0.6 2.9 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) compare
Shew_1851 +0.6 0.7 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_1111 +0.6 1.9 LacI family transcription regulator (RefSeq) compare
Shew_1821 +0.6 1.6 2-methylcitrate synthase/citrate synthase II (RefSeq) compare
Shew_0626 +0.5 1.9 hypothetical protein (RefSeq) compare
Shew_1854 +0.5 1.0 hypothetical protein (RefSeq) compare
Shew_0584 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_2022 +0.5 0.7 recombination factor protein RarA (RefSeq) compare
Shew_2074 +0.5 2.2 TonB-dependent receptor (RefSeq) compare
Shew_2748 +0.5 2.7 PAS/PAC sensor signal transduction histidine kinase (RefSeq) compare
Shew_1273 +0.5 0.9 hypothetical protein (RefSeq) compare
Shew_2121 +0.5 1.0 diguanylate cyclase (RefSeq) compare
Shew_0453 +0.5 1.0 response regulator receiver protein (RefSeq) compare
Shew_2570 +0.5 4.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_2337 tgt +0.5 2.1 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_0430 +0.5 1.5 histone family protein DNA-binding protein (RefSeq) compare
Shew_1926 +0.5 1.1 transketolase, central region (RefSeq) compare
Shew_1455 +0.5 0.7 dual specificity protein phosphatase (RefSeq) compare
Shew_0570 +0.5 0.8 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_0684 +0.5 1.6 hypothetical protein (RefSeq) compare
Shew_2423 +0.5 2.1 hypothetical protein (RefSeq) compare
Shew_3260 +0.5 4.1 porin (RefSeq) compare
Shew_2687 +0.5 1.7 hypothetical protein (RefSeq) compare
Shew_1530 +0.5 2.0 porin (RefSeq) compare
Shew_1189 +0.5 3.6 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_3055 +0.5 1.5 CMP/dCMP deaminase, zinc-binding (RefSeq) compare
Shew_3408 +0.5 3.8 hypothetical protein (RefSeq) compare
Shew_1563 +0.5 3.8 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_0885 djlA +0.5 0.7 DNA-J like membrane chaperone protein (RefSeq) compare
Shew_1058 +0.5 2.1 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_2723 +0.5 1.9 NUDIX hydrolase (RefSeq) compare
Shew_0496 +0.5 1.3 amino acid carrier protein (RefSeq) compare
Shew_3653 +0.5 0.6 hypothetical protein (RefSeq) compare
Shew_3392 +0.5 3.8 ornithine decarboxylase (RefSeq) compare
Shew_1865 +0.5 2.5 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_0707 +0.5 1.2 YbaK/prolyl-tRNA synthetase associated region (RefSeq) compare
Shew_2700 +0.5 1.8 antibiotic biosynthesis monooxygenase (RefSeq) compare


Specific Phenotypes

For 2 genes in this experiment

For stress 1-ethyl-3-methylimidazolium chloride in Shewanella loihica PV-4

For stress 1-ethyl-3-methylimidazolium chloride across organisms