Experiment set4IT023 for Shewanella loihica PV-4

Compare to:

LB with 1-ethyl-3-methylimidazolium acetate 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_2572 +2.6 14.0 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1809 +2.4 17.3 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_1301 +2.4 19.9 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_1512 +2.2 11.5 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_2049 +2.2 13.3 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_1224 +2.2 17.6 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1298 guaA +2.2 17.2 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_3412 purH +2.2 14.9 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_3431 aceE +2.1 16.2 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_0296 +2.1 3.0 heat shock protein Hsp20 (RefSeq) compare
Shew_3413 +2.1 11.9 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_1128 +2.1 11.9 LysR family transcriptional regulator (RefSeq) compare
Shew_2302 +2.0 11.3 amidophosphoribosyltransferase (RefSeq) compare
Shew_1013 +2.0 16.9 aspartate carbamoyltransferase (RefSeq) compare
Shew_1819 +2.0 7.1 GntR family transcriptional regulator (RefSeq) compare
Shew_3488 +1.9 5.9 ribonuclease PH (RefSeq) compare
Shew_3430 +1.8 4.0 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_3432 pdhR +1.8 3.6 transcriptional regulator PdhR (RefSeq) compare
Shew_3225 +1.7 10.7 glutathione synthetase (RefSeq) compare
Shew_0534 +1.7 4.9 major facilitator transporter (RefSeq) compare
Shew_2502 +1.6 6.5 ABC transporter-related protein (RefSeq) compare
Shew_1186 +1.6 3.0 transcriptional regulator NrdR (RefSeq) compare
Shew_3710 tdh +1.6 12.4 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1230 +1.5 4.6 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_2000 +1.5 2.2 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2571 +1.5 8.3 propionyl-CoA carboxylase (RefSeq) compare
Shew_3709 +1.5 13.1 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1822 +1.5 5.9 aconitate hydratase (RefSeq) compare
Shew_2320 +1.5 9.5 RNA methyltransferase (RefSeq) compare
Shew_0755 +1.4 6.5 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_2838 carB +1.4 12.1 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_3487 pyrE +1.4 5.2 orotate phosphoribosyltransferase (RefSeq) compare
Shew_2812 deoD +1.4 6.9 purine nucleoside phosphorylase (RefSeq) compare
Shew_3378 +1.4 3.0 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_2839 +1.4 9.1 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_0330 +1.4 1.0 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_1210 +1.3 5.4 stationary-phase survival protein SurE (RefSeq) compare
Shew_0086 +1.3 10.9 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_0763 +1.3 7.9 putative PAS/PAC sensor protein (RefSeq) compare
Shew_2382 +1.2 10.1 cysteine synthase A (RefSeq) compare
Shew_3621 +1.2 1.8 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_2481 +1.2 7.8 porin (RefSeq) compare
Shew_3708 +1.2 9.2 TetR family transcriptional regulator (RefSeq) compare
Shew_2584 +1.2 9.0 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_2211 +1.2 2.6 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_2770 +1.2 1.3 polyprenyl synthetase (RefSeq) compare
Shew_1302 +1.2 6.0 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_3377 +1.2 1.3 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_0022 +1.1 9.4 TrkH family potassium uptake protein (RefSeq) compare
Shew_3499 +1.1 5.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_0359 fre +1.1 5.9 FMN reductase (RefSeq) compare
Shew_3500 +1.1 3.4 putative endoribonuclease L-PSP (RefSeq) compare
Shew_0326 +1.1 4.4 HAD family hydrolase (RefSeq) compare
Shew_1341 +1.1 3.2 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_2573 +1.1 8.1 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_3189 +1.1 3.9 hypothetical protein (RefSeq) compare
Shew_1559 +1.1 1.3 hypothetical protein (RefSeq) compare
Shew_1673 fabG +1.1 2.3 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_3295 +1.0 6.0 AFG1 family ATPase (RefSeq) compare
Shew_0728 +1.0 6.8 dihydroorotase (RefSeq) compare
Shew_3664 +1.0 8.0 alpha-L-glutamate ligase (RefSeq) compare
Shew_2814 deoA +1.0 3.5 thymidine phosphorylase (RefSeq) compare
Shew_0320 +1.0 7.1 frataxin family protein (RefSeq) compare
Shew_2008 +1.0 1.5 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_0462 +1.0 1.1 hypothetical protein (RefSeq) compare
Shew_2498 +1.0 1.5 extracellular solute-binding protein (RefSeq) compare
Shew_3681 +1.0 5.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0421 +0.9 1.2 phage shock protein C, PspC (RefSeq) compare
Shew_1823 +0.9 2.4 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_0127 +0.9 3.3 LexA repressor (RefSeq) compare
Shew_1227 +0.9 1.5 glutamate--cysteine ligase (RefSeq) compare
Shew_1439 +0.9 5.3 maleylacetoacetate isomerase (RefSeq) compare
Shew_2414 +0.9 1.4 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_1188 +0.9 3.2 riboflavin synthase subunit alpha (RefSeq) compare
Shew_1425 +0.9 2.9 adenylyl-sulfate kinase (RefSeq) compare
Shew_0342 +0.9 4.4 hypothetical protein (RefSeq) compare
Shew_1185 glyA +0.9 4.8 serine hydroxymethyltransferase (RefSeq) compare
Shew_0540 +0.9 2.8 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1050 +0.9 4.1 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_3622 hslO +0.9 5.9 Hsp33-like chaperonin (RefSeq) compare
Shew_1438 +0.9 3.2 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_2837 +0.9 0.9 transcription elongation factor GreA (RefSeq) compare
Shew_2962 +0.9 3.0 malate dehydrogenase (RefSeq) compare
Shew_1951 +0.9 4.5 aromatic amino acid aminotransferase (RefSeq) compare
Shew_1810 +0.9 4.0 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_2813 +0.9 2.0 phosphopentomutase (RefSeq) compare
Shew_3560 +0.9 3.8 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_1189 +0.9 6.4 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_3273 +0.8 3.4 hypothetical protein (RefSeq) compare
Shew_0216 +0.8 1.1 DNA adenine methylase (RefSeq) compare
Shew_2409 +0.8 2.5 short chain dehydrogenase (RefSeq) compare
Shew_2558 +0.8 3.4 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_3311 +0.8 4.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3759 +0.8 6.5 imidazolonepropionase (RefSeq) compare
Shew_3224 +0.8 3.9 hypothetical protein (RefSeq) compare
Shew_0191 +0.8 1.7 cytochrome c, class I (RefSeq) compare
Shew_3628 +0.8 1.4 MgtC/SapB transporter (RefSeq) compare
Shew_3312 +0.8 3.2 sigma 54 modulation protein/ribosomal protein S30EA (RefSeq) compare
Shew_1437 +0.8 4.5 transcriptional regulator, TyrR (RefSeq) compare
Shew_0930 +0.8 1.6 AMMECR1 domain-containing protein (RefSeq) compare
Shew_1078 +0.8 5.8 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_3316 +0.7 5.0 magnesium transporter (RefSeq) compare
Shew_2285 +0.7 1.1 UDP-glucose 4-epimerase (RefSeq) compare
Shew_0613 +0.7 4.6 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_3682 +0.7 5.9 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_0618 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_2919 +0.7 2.1 translation-associated GTPase (RefSeq) compare
Shew_1820 prpB +0.7 1.8 2-methylisocitrate lyase (RefSeq) compare
Shew_1035 +0.7 1.0 LysR family transcriptional regulator (RefSeq) compare
Shew_0193 +0.7 1.9 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_2025 +0.7 4.3 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_1092 +0.7 5.1 amino acid carrier protein (RefSeq) compare
Shew_3548 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1927 +0.7 1.4 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1851 +0.7 0.9 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_2410 +0.7 0.5 beta-ketoacyl synthase (RefSeq) compare
Shew_1402 +0.7 4.5 glucose-1-phosphate thymidylyltransferase (RefSeq) compare
Shew_2939 +0.7 2.5 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) compare
Shew_2361 +0.7 1.4 proline racemase (RefSeq) compare
Shew_2820 prfC +0.7 1.4 peptide chain release factor 3 (RefSeq) compare
Shew_2241 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_1620 +0.7 3.1 adenosylmethionine decarboxylase (RefSeq) compare
Shew_0615 +0.6 5.0 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_1594 +0.6 3.3 RluA family pseudouridine synthase (RefSeq) compare
Shew_0430 +0.6 2.0 histone family protein DNA-binding protein (RefSeq) compare
Shew_1714 +0.6 2.4 alpha/beta hydrolase fold (RefSeq) compare
Shew_2504 +0.6 1.9 PpiC-type peptidyl-prolyl cis-trans isomerase (RefSeq) compare
Shew_1287 +0.6 1.7 hypothetical protein (RefSeq) compare
Shew_0627 +0.6 3.8 hypothetical protein (RefSeq) compare
Shew_2035 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_2337 tgt +0.6 2.5 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_0526 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_0531 +0.6 2.3 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_0932 +0.6 1.0 radical SAM domain-containing protein (RefSeq) compare
Shew_2347 +0.6 2.0 phosphonate ABC transporter, periplasmic phosphonate-binding protein (RefSeq) compare
Shew_0686 +0.6 1.3 DSBA oxidoreductase (RefSeq) compare
Shew_0580 +0.6 1.2 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_3556 +0.6 2.2 aminotransferase, class V (RefSeq) compare
Shew_3267 +0.6 3.7 sodium/hydrogen exchanger (RefSeq) compare
Shew_3568 +0.6 3.3 cation diffusion facilitator family transporter (RefSeq) compare
Shew_1926 +0.6 1.5 transketolase, central region (RefSeq) compare
Shew_3686 +0.6 3.9 molybdopterin-guanine dinucleotide biosynthesis protein A (RefSeq) compare
Shew_1925 +0.6 2.6 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_3261 +0.6 1.2 thiopurine S-methyltransferase (RefSeq) compare
Shew_3062 +0.6 5.3 glycine dehydrogenase (RefSeq) compare
Shew_3122 +0.6 0.7 PepSY-associated TM helix domain-containing protein (RefSeq) compare
Shew_1015 +0.6 2.8 Cl- channel, voltage-gated family protein (RefSeq) compare
Shew_3197 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_3065 +0.6 3.4 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_0777 +0.6 0.7 two-component response regulator (RefSeq) compare
Shew_1914 +0.6 2.0 aminotransferase AlaT (RefSeq) compare
Shew_2957 +0.6 2.3 hypothetical protein (RefSeq) compare
Shew_3481 +0.6 2.3 DNA repair protein RadC (RefSeq) compare
Shew_2191 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_0889 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_0268 +0.6 1.1 transcriptional antiterminator, Rof (RefSeq) compare
Shew_3176 +0.6 1.1 regulatory protein GntR, HTH (RefSeq) compare
Shew_3121 +0.6 1.4 FMN-binding domain-containing protein (RefSeq) compare
Shew_0860 +0.6 1.8 hypothetical protein (RefSeq) compare
Shew_2652 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_2514 +0.6 1.8 tRNA--hydroxylase (RefSeq) compare
Shew_1574 +0.6 2.5 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_1486 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_2074 +0.6 2.8 TonB-dependent receptor (RefSeq) compare
Shew_0626 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_3266 dipZ +0.5 0.8 thiol:disulfide interchange protein precursor (RefSeq) compare
Shew_1263 +0.5 1.6 hypothetical protein (RefSeq) compare
Shew_0570 +0.5 0.9 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_3446 +0.5 2.9 peptidase M23B (RefSeq) compare
Shew_3022 +0.5 1.8 hypothetical protein (RefSeq) compare
Shew_0220 +0.5 2.5 phosphoglycolate phosphatase (RefSeq) compare
Shew_0516 +0.5 2.0 cytochrome c family protein (RefSeq) compare
Shew_0401 +0.5 1.0 MSHA biogenesis protein MshP (RefSeq) compare
Shew_1649 +0.5 1.5 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0453 +0.5 1.0 response regulator receiver protein (RefSeq) compare
Shew_2147 +0.5 1.1 hypothetical protein (RefSeq) compare
Shew_3711 +0.5 0.5 rhodanese domain-containing protein (RefSeq) compare
Shew_2461 +0.5 2.1 MORN repeat-containing protein (RefSeq) compare
Shew_1935 +0.5 2.7 hypothetical protein (RefSeq) compare
Shew_2202 +0.5 0.7 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) compare
Shew_2033 +0.5 1.5 hypothetical protein (RefSeq) compare
Shew_1865 +0.5 3.1 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_2087 +0.5 1.7 hypothetical protein (RefSeq) compare
Shew_2570 +0.5 4.4 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1266 +0.5 0.8 XRE family transcriptional regulator (RefSeq) compare
Shew_2646 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_3395 +0.5 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_1411 +0.5 3.3 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_1878 +0.5 1.5 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0571 +0.5 1.4 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_1490 +0.5 0.5 ErfK/YbiS/YcfS/YnhG family protein (RefSeq) compare
Shew_3537 +0.5 1.5 hypothetical protein (RefSeq) compare
Shew_3687 +0.5 4.0 molybdopterin-guanine dinucleotide biosynthesis protein B (RefSeq) compare
Shew_0995 +0.5 1.8 phage integrase family protein (RefSeq) compare
Shew_1922 +0.5 1.8 phosphoglucomutase (RefSeq) compare
Shew_1937 +0.5 3.0 peptidase M14, carboxypeptidase A (RefSeq) compare
Shew_3323 +0.5 1.4 lipase-like (RefSeq) compare
Shew_2121 +0.5 1.5 diguanylate cyclase (RefSeq) compare
Shew_1675 +0.5 2.7 peptidase S9 prolyl oligopeptidase (RefSeq) compare
Shew_0885 djlA +0.5 0.8 DNA-J like membrane chaperone protein (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress 1-ethyl-3-methylimidazolium acetate in Shewanella loihica PV-4

For stress 1-ethyl-3-methylimidazolium acetate across organisms