Experiment set4IT023 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Rifampicin 0.001 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_1351 +1.5 12.7 signal peptide peptidase SppA, 67K type compare
Ga0059261_1310 +1.3 5.4 Predicted transcriptional regulators compare
Ga0059261_3153 +1.2 4.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_3807 +1.0 5.4 Uncharacterized conserved protein compare
Ga0059261_4142 +1.0 2.7 hypothetical protein compare
Ga0059261_1043 +0.9 4.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_1574 +0.8 4.0 Superfamily II DNA and RNA helicases compare
Ga0059261_3783 +0.8 3.9 hypothetical protein compare
Ga0059261_2018 +0.8 5.9 hypothetical protein compare
Ga0059261_0850 +0.7 2.3 hypothetical protein compare
Ga0059261_1610 +0.7 4.3 CBS domain/Transporter associated domain compare
Ga0059261_2466 +0.7 5.8 DnaJ domain/DnaJ C terminal domain compare
Ga0059261_2020 +0.7 5.7 Glycosyltransferase compare
Ga0059261_0266 +0.7 1.7 hypothetical protein compare
Ga0059261_2019 +0.7 2.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_1799 +0.7 2.6 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_1876 +0.7 4.5 Predicted membrane protein compare
Ga0059261_3637 +0.6 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_4185 +0.6 1.4 hypothetical protein compare
Ga0059261_3569 +0.6 2.2 chaperone protein DnaJ compare
Ga0059261_3784 +0.6 5.0 DNA mismatch repair protein MutS compare
Ga0059261_3356 +0.6 1.1 hypothetical protein compare
Ga0059261_0411 +0.6 1.8 Uncharacterized conserved protein compare
Ga0059261_3437 +0.6 1.5 hypothetical protein compare
Ga0059261_0242 +0.6 1.6 hypothetical protein compare
Ga0059261_2086 +0.6 1.2 SAF-like compare
Ga0059261_0814 +0.6 2.9 hypothetical protein compare
Ga0059261_3579 +0.6 2.6 hypothetical protein compare
Ga0059261_0174 +0.6 0.8 hypothetical protein compare
Ga0059261_3598 +0.6 2.4 Flp pilus assembly protein, pilin Flp compare
Ga0059261_0818 +0.5 4.6 OmpA family compare
Ga0059261_0208 +0.5 2.6 Response regulator receiver domain compare
Ga0059261_0811 +0.5 1.9 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family compare
Ga0059261_3367 +0.5 2.8 hypothetical protein compare
Ga0059261_1611 +0.5 4.8 Glucose/sorbosone dehydrogenases compare
Ga0059261_0980 +0.5 3.2 polyhydroxyalkanoate synthesis repressor PhaR compare
Ga0059261_0344 +0.5 2.1 Molecular chaperone (small heat shock protein) compare
Ga0059261_3491 +0.5 3.7 hypothetical protein compare
Ga0059261_2448 +0.5 1.6 DNA protecting protein DprA compare
Ga0059261_2378 +0.5 1.5 phage virion morphogenesis (putative tail completion) protein compare
Ga0059261_1527 +0.5 1.3 hypothetical protein compare
Ga0059261_1262 +0.5 4.3 cobaltochelatase CobS subunit (EC 6.6.1.2) compare
Ga0059261_0906 +0.5 2.8 Uncharacterized conserved protein compare
Ga0059261_2914 +0.5 1.7 Type IV secretory pathway, TrbD component compare
Ga0059261_1260 +0.5 3.6 cobaltochelatase CobT subunit (EC 6.6.1.2) compare
Ga0059261_1577 +0.5 4.4 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_2744 +0.5 3.9 CDP-alcohol phosphatidyltransferase compare
Ga0059261_2309 +0.5 2.5 transcriptional regulator, LacI family compare
Ga0059261_2745 +0.5 4.1 Myo-inositol-1-phosphate synthase compare
Ga0059261_3882 +0.5 1.6 dimethyladenosine transferase (EC 2.1.1.-) compare
Ga0059261_2916 +0.5 1.7 P-type conjugative transfer protein TrbJ compare
Ga0059261_2730 +0.5 1.0 Sortase and related acyltransferases compare
Ga0059261_1022 +0.5 2.0 hypothetical protein compare
Ga0059261_3992 +0.5 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_1872 +0.5 2.6 HAD-superfamily subfamily IB hydrolase, TIGR01490 compare
Ga0059261_2351 +0.5 1.8 hypothetical protein compare
Ga0059261_0255 +0.5 1.6 SurA N-terminal domain/PPIC-type PPIASE domain compare
Ga0059261_2132 +0.5 1.4 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_3995 +0.4 2.9 succinylarginine dihydrolase (EC 3.5.3.23) compare
Ga0059261_0057 +0.4 4.1 Glycosyltransferase compare
Ga0059261_3562 +0.4 2.0 Glycosyltransferase compare
Ga0059261_0102 +0.4 3.3 endopeptidase La compare
Ga0059261_4225 +0.4 2.3 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0350 +0.4 2.8 Bacterial SH3 domain compare
Ga0059261_0983 +0.4 4.0 TonB dependent receptor/TonB-dependent Receptor Plug Domain compare
Ga0059261_0720 +0.4 1.5 Predicted small integral membrane protein compare
Ga0059261_0060 +0.4 1.3 Uncharacterized conserved protein compare
Ga0059261_0656 +0.4 1.6 Predicted dehydrogenases and related proteins compare
Ga0059261_1625 +0.4 2.9 2-keto-3-deoxy-6-phosphogluconate aldolase compare
Ga0059261_2089 +0.4 2.5 flagellar basal-body rod protein FlgB compare
Ga0059261_4192 +0.4 1.6 ATPases involved in chromosome partitioning compare
Ga0059261_0815 +0.4 3.5 Uncharacterized protein involved in tellurite resistance compare
Ga0059261_0911 +0.4 1.7 Domain of unknown function (DUF3597) compare
Ga0059261_4196 +0.4 3.2 FemAB-related protein, PEP-CTERM system-associated compare
Ga0059261_3708 +0.4 2.5 GAF domain-containing protein compare
Ga0059261_3233 +0.4 2.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0686 +0.4 2.9 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Ga0059261_2277 +0.4 1.2 hypothetical protein compare
Ga0059261_4146 +0.4 1.6 phage shock protein B compare
Ga0059261_1762 +0.4 0.9 hypothetical protein compare
Ga0059261_1316 +0.4 0.7 hypothetical protein compare
Ga0059261_1847 +0.4 1.8 hypothetical protein compare
Ga0059261_4224 +0.4 0.8 hypothetical protein compare
Ga0059261_3684 +0.4 1.6 hypothetical protein compare
Ga0059261_2065 +0.4 1.8 Flagellar motor switch protein compare
Ga0059261_2347 +0.4 1.1 hypothetical protein compare
Ga0059261_2090 +0.4 2.2 flagellar basal-body rod protein FlgC compare
Ga0059261_4140 +0.4 0.8 hypothetical protein compare
Ga0059261_1311 +0.4 1.7 Nitroreductase compare
Ga0059261_0657 +0.4 0.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_2830 +0.3 1.7 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_3900 +0.3 2.0 Transcriptional regulators compare
Ga0059261_2062 +0.3 1.9 flagellar biosynthetic protein FliP compare
Ga0059261_2060 +0.3 2.5 flagellar biosynthetic protein FliR compare
Ga0059261_1595 +0.3 3.2 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_0650 +0.3 0.8 Negative regulator of beta-lactamase expression compare
Ga0059261_1208 +0.3 1.9 hypothetical protein compare
Ga0059261_2400 +0.3 1.8 Uncharacterized conserved protein compare
Ga0059261_2768 +0.3 0.8 hypothetical protein compare
Ga0059261_2017 +0.3 2.6 Glycosyltransferase compare
Ga0059261_2143 +0.3 1.7 Zn-dependent proteases compare
Ga0059261_0894 +0.3 1.7 hypothetical protein compare
Ga0059261_2761 +0.3 2.5 Lactoylglutathione lyase and related lyases compare
Ga0059261_3796 +0.3 2.3 Predicted transcriptional regulator compare
Ga0059261_2245 +0.3 2.5 hypothetical protein compare
Ga0059261_2048 +0.3 2.3 Thiol-disulfide isomerase and thioredoxins compare
Ga0059261_1315 +0.3 1.2 Alpha/beta hydrolase family compare
Ga0059261_0816 +0.3 1.1 hypothetical protein compare
Ga0059261_0976 +0.3 2.0 Aspartyl protease compare
Ga0059261_2063 +0.3 1.6 Flagellar biosynthesis protein, FliO compare
Ga0059261_2978 +0.3 1.4 Transcriptional regulators compare
Ga0059261_3206 +0.3 2.0 ornithine carbamoyltransferase compare
Ga0059261_2077 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_3940 +0.3 1.8 hypothetical protein compare
Ga0059261_2736 +0.3 1.5 hypothetical protein compare
Ga0059261_1032 +0.3 1.4 protein CrcB compare
Ga0059261_0723 +0.3 1.3 hypothetical protein compare
Ga0059261_3426 +0.3 2.2 Cold shock proteins compare
Ga0059261_1286 +0.3 1.7 phasin family protein compare
Ga0059261_3666 +0.3 1.5 molybdenum ABC transporter, periplasmic molybdate-binding protein compare
Ga0059261_2746 +0.3 1.5 Predicted sugar nucleotidyltransferases compare
Ga0059261_3132 +0.3 1.6 hypothetical protein compare
Ga0059261_3997 +0.3 1.6 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Ga0059261_3411 +0.3 1.8 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_2255 +0.3 1.6 nitrogen regulatory protein P-II family compare
Ga0059261_1300 +0.3 1.3 hypothetical protein compare
Ga0059261_3752 +0.3 1.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_3817 +0.3 1.5 Predicted NTP pyrophosphohydrolase compare
Ga0059261_2721 +0.3 1.5 rare lipoprotein A compare
Ga0059261_1396 +0.3 1.2 EF-hand domain pair compare
Ga0059261_2044 +0.3 2.0 peptide chain release factor 3 compare
Ga0059261_3862 +0.3 1.5 Multidrug resistance efflux pump compare
Ga0059261_2072 +0.3 2.0 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Ga0059261_1783 +0.3 1.7 Transposase and inactivated derivatives compare
Ga0059261_3056 +0.3 0.8 Protein of unknown function (DUF2958) compare
Ga0059261_3435 +0.3 1.7 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_2706 +0.3 1.9 CAAX protease self-immunity compare
Ga0059261_4143 +0.3 0.7 hypothetical protein compare
Ga0059261_3546 +0.3 1.7 hypothetical protein compare
Ga0059261_4046 +0.3 0.7 Response regulator receiver domain compare
Ga0059261_1095 +0.3 1.7 Flagellar motor switch protein compare
Ga0059261_0405 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_1530 +0.3 1.3 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Ga0059261_2716 +0.3 1.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_1763 +0.3 1.0 hypothetical protein compare
Ga0059261_1546 +0.3 1.9 MerC mercury resistance protein compare
Ga0059261_2796 +0.3 1.7 hypothetical protein compare
Ga0059261_1138 +0.3 1.1 hypothetical protein compare
Ga0059261_3376 +0.3 1.7 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Ga0059261_1890 +0.3 1.5 transcriptional regulator, LacI family compare
Ga0059261_3395 +0.3 1.2 hypothetical protein compare
Ga0059261_0897 +0.3 2.0 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1991 +0.3 1.3 hypothetical protein compare
Ga0059261_0284 +0.3 1.7 Leucyl aminopeptidase compare
Ga0059261_2362 +0.3 2.0 Phage protein D compare
Ga0059261_3985 +0.3 1.5 methylmalonyl-CoA epimerase (EC 5.1.99.1) compare
Ga0059261_2531 +0.3 1.0 conserved hypothetical integral membrane protein compare
Ga0059261_2083 +0.3 2.1 hypothetical protein compare
Ga0059261_2603 +0.3 2.0 hypothetical protein compare
Ga0059261_2091 +0.3 1.5 Flagellar hook capping protein compare
Ga0059261_3364 +0.3 2.2 PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family compare
Ga0059261_3839 +0.3 1.1 hypothetical protein compare
Ga0059261_0059 +0.2 0.8 Stress-induced morphogen (activity unknown) compare
Ga0059261_3507 +0.2 2.2 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_0351 +0.2 1.8 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
Ga0059261_3034 +0.2 1.9 Cation efflux family compare
Ga0059261_1196 +0.2 1.0 hypothetical protein compare
Ga0059261_0390 +0.2 0.4 Ribbon-helix-helix protein, copG family compare
Ga0059261_1261 +0.2 0.4 hypothetical protein compare
Ga0059261_0270 +0.2 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_2998 +0.2 1.2 periplasmic chaperone for outer membrane proteins Skp compare
Ga0059261_3930 +0.2 2.0 Putative protein-S-isoprenylcysteine methyltransferase compare
Ga0059261_3438 +0.2 1.6 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Ga0059261_2076 +0.2 0.4 hypothetical protein compare
Ga0059261_0594 +0.2 1.6 RND family efflux transporter, MFP subunit compare
Ga0059261_1385 +0.2 2.2 Glycosyltransferase compare
Ga0059261_3535 +0.2 2.2 Methyltransferase domain compare
Ga0059261_3236 +0.2 2.1 pyruvate phosphate dikinase (EC 2.7.9.1) compare
Ga0059261_1571 +0.2 2.1 SapC compare
Ga0059261_2058 +0.2 2.0 Flagellar capping protein compare
Ga0059261_2685 +0.2 1.2 Putative translation initiation inhibitor, yjgF family compare
Ga0059261_3659 +0.2 1.1 PqqD family protein, HPr-rel-A system compare
Ga0059261_2847 +0.2 1.6 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_0812 +0.2 0.9 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_0756 +0.2 1.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_0982 +0.2 1.5 acetyl-CoA acetyltransferases compare
Ga0059261_0628 +0.2 1.2 L-threonine O-3-phosphate decarboxylase (EC 4.1.1.81) compare
Ga0059261_0385 +0.2 1.3 P-type conjugative transfer protein TrbJ compare
Ga0059261_0921 +0.2 0.6 hypothetical protein compare
Ga0059261_3360 +0.2 1.4 Dienelactone hydrolase and related enzymes compare
Ga0059261_2871 +0.2 1.4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_0955 +0.2 1.3 PilZ domain compare
Ga0059261_1195 +0.2 1.0 Co/Zn/Cd efflux system component compare
Ga0059261_3407 +0.2 1.7 Superfamily II DNA and RNA helicases compare
Ga0059261_3139 +0.2 1.2 Predicted membrane protein compare
Ga0059261_3278 +0.2 1.8 Uncharacterized conserved protein compare
Ga0059261_2094 +0.2 1.6 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Ga0059261_0846 +0.2 1.2 Zn-dependent alcohol dehydrogenases, class III compare
Ga0059261_3860 +0.2 1.7 Ku protein, prokaryotic compare
Ga0059261_2363 +0.2 1.6 Phage P2 GpU compare


Specific Phenotypes

For 10 genes in this experiment

For stress Rifampicin in Sphingomonas koreensis DSMZ 15582

For stress Rifampicin across organisms