Experiment set4IT021 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Gentamicin sulfate salt 0.015 mg/ml

200 most important genes:

  gene name fitness t score description  
Ga0059261_2707 -3.1 -7.0 fructose-1,6-bisphosphatase, class II compare
Ga0059261_1482 -2.9 -15.9 Acetyltransferase (GNAT) family conserved
Ga0059261_1369 -2.9 -13.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_0163 -2.8 -4.5 Major Facilitator Superfamily compare
Ga0059261_1370 -2.7 -10.5 Signal transduction histidine kinase compare
Ga0059261_0175 -2.6 -9.2 heme exporter protein CcmC compare
Ga0059261_3615 -2.5 -2.9 hypothetical protein compare
Ga0059261_0170 -2.4 -5.7 Uncharacterized protein involved in biosynthesis of c-type cytochromes compare
Ga0059261_0172 -2.4 -9.7 Cytochrome c biogenesis factor compare
Ga0059261_2417 -2.3 -4.7 phytoene desaturase compare
Ga0059261_2137 -2.3 -16.9 ABC-type multidrug transport system, ATPase and permease components compare
Ga0059261_4188 -2.3 -7.9 pyridoxal-dependent decarboxylase, exosortase A system-associated compare
Ga0059261_3341 -2.3 -8.4 ATP-dependent protease HslVU, peptidase subunit compare
Ga0059261_2013 -2.2 -14.3 signal peptidase I, bacterial type compare
Ga0059261_4187 -2.2 -11.0 acyl-CoA ligase (AMP-forming), exosortase A-associated compare
Ga0059261_1368 -2.0 -3.3 hypothetical protein compare
Ga0059261_1483 -2.0 -12.8 acetyl-CoA acetyltransferases compare
Ga0059261_2190 -2.0 -5.6 PTS IIA-like nitrogen-regulatory protein PtsN compare
Ga0059261_0790 -2.0 -3.3 putative membrane protein insertion efficiency factor compare
Ga0059261_3339 -1.9 -8.4 ATP-dependent protease HslVU, ATPase subunit compare
Ga0059261_2514 -1.8 -12.1 phosphoenolpyruvate-protein phosphotransferase compare
Ga0059261_3506 -1.8 -1.8 Predicted permeases compare
Ga0059261_4186 -1.7 -2.5 Phosphopantetheine attachment site compare
Ga0059261_0613 -1.7 -3.8 FecR family protein compare
Ga0059261_2005 -1.6 -5.0 protoheme IX farnesyltransferase compare
Ga0059261_2444 -1.6 -6.8 5-aminolevulinic acid synthase compare
Ga0059261_0950 -1.5 -4.1 Uncharacterized protein conserved in bacteria (DUF2336) compare
Ga0059261_2181 -1.5 -10.9 penicillin-binding protein, 1A family compare
Ga0059261_1507 -1.5 -3.3 deoxycytidine triphosphate deaminase compare
Ga0059261_3103 -1.5 -3.6 Glycosyltransferase compare
Ga0059261_2490 -1.5 -5.4 Small protein A (tmRNA-binding) compare
Ga0059261_0349 -1.4 -4.3 MarR family compare
Ga0059261_3119 -1.4 -4.6 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_1928 -1.4 -4.6 Predicted permeases compare
Ga0059261_1605 -1.4 -7.1 transcriptional regulator, TetR family compare
Ga0059261_0255 -1.4 -3.3 SurA N-terminal domain/PPIC-type PPIASE domain compare
Ga0059261_0918 -1.3 -5.7 Phosphotransferase system, mannose/fructose-specific component IIA compare
Ga0059261_3340 -1.3 -7.1 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) compare
Ga0059261_2189 -1.3 -6.0 uncharacterized domain 1 compare
Ga0059261_0197 -1.3 -1.8 hypothetical protein compare
Ga0059261_3276 -1.3 -7.2 ABC-type multidrug transport system, ATPase and permease components compare
Ga0059261_3097 -1.2 -5.2 Calcineurin-like phosphoesterase compare
Ga0059261_3101 -1.2 -3.6 nucleotide sugar dehydrogenase compare
Ga0059261_0879 -1.2 -8.0 ribosomal RNA small subunit methyltransferase A compare
Ga0059261_0171 -1.2 -1.8 Thiol-disulfide isomerase and thioredoxins compare
Ga0059261_0951 -1.2 -5.4 hypothetical protein compare
Ga0059261_0245 -1.2 -2.4 pseudouridine synthase compare
Ga0059261_0369 -1.2 -2.2 ribosomal protein L9 compare
Ga0059261_2481 -1.2 -5.1 Ppx/GppA phosphatase family compare
Ga0059261_1870 -1.1 -5.9 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Ga0059261_1382 -1.1 -5.8 periplasmic serine protease, Do/DeqQ family compare
Ga0059261_1869 -1.1 -4.9 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Ga0059261_1293 -1.1 -7.5 (p)ppGpp synthetase, RelA/SpoT family compare
Ga0059261_1909 -1.1 -5.8 MAF protein compare
Ga0059261_3114 -1.1 -6.2 hypothetical protein compare
Ga0059261_3160 -1.1 -3.1 TolQ protein compare
Ga0059261_3490 -1.1 -6.3 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_2418 -1.0 -4.2 lycopene cyclase compare
Ga0059261_2529 -1.0 -5.5 Predicted integral membrane protein compare
Ga0059261_1451 -1.0 -4.1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) compare
Ga0059261_1929 -1.0 -4.1 Putative transmembrane protein (Alph_Pro_TM) compare
Ga0059261_0321 -1.0 -2.0 hypothetical protein compare
Ga0059261_3748 -1.0 -2.7 ribosomal protein L15, bacterial/organelle compare
Ga0059261_0012 -1.0 -4.9 Protein of unknown function (DUF1469) compare
Ga0059261_2002 -1.0 -5.3 Heme/copper-type cytochrome/quinol oxidase, subunit 3 compare
Ga0059261_3191 -1.0 -4.8 Glycosyltransferases involved in cell wall biogenesis compare
Ga0059261_1017 -1.0 -5.1 tRNA-guanine transglycosylase compare
Ga0059261_3130 -1.0 -5.9 Lipid A core - O-antigen ligase and related enzymes compare
Ga0059261_1696 -0.9 -3.4 Pyridine nucleotide-disulphide oxidoreductase/Reductase C-terminal compare
Ga0059261_1872 -0.9 -3.9 HAD-superfamily subfamily IB hydrolase, TIGR01490 compare
Ga0059261_1842 -0.9 -8.1 Protease II compare
Ga0059261_3481 -0.9 -4.9 Beta-glucosidase-related glycosidases compare
Ga0059261_0013 -0.9 -2.9 hypothetical protein compare
Ga0059261_3227 -0.9 -1.8 GTP-binding protein YchF compare
Ga0059261_4055 -0.9 -6.3 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) compare
Ga0059261_1871 -0.9 -6.5 ABC transport permease subunit compare
Ga0059261_0361 -0.9 -6.8 conserved hypothetical protein, YceG family compare
Ga0059261_3157 -0.9 -7.1 tol-pal system beta propeller repeat protein TolB compare
Ga0059261_2191 -0.9 -5.5 ribosomal subunit interface protein compare
Ga0059261_0757 -0.9 -2.7 Predicted transcriptional regulators compare
Ga0059261_1287 -0.8 -5.4 poly(R)-hydroxyalkanoic acid synthase, class I compare
Ga0059261_0131 -0.8 -3.5 hypothetical protein compare
Ga0059261_3156 -0.8 -3.5 peptidoglycan-associated lipoprotein compare
Ga0059261_3579 -0.8 -4.3 hypothetical protein compare
Ga0059261_3492 -0.8 -4.0 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_1386 -0.8 -4.2 7-cyano-7-deazaguanine reductase compare
Ga0059261_2754 -0.8 -6.8 ABC-type branched-chain amino acid transport systems, periplasmic component compare
Ga0059261_2295 -0.8 -1.9 DUF218 domain compare
Ga0059261_1564 -0.8 -3.2 cytochrome bo3 quinol oxidase subunit 3 (EC 1.10.3.-) compare
Ga0059261_3129 -0.8 -4.8 SLBB domain/Polysaccharide biosynthesis/export protein compare
Ga0059261_3512 -0.7 -1.1 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
Ga0059261_1547 -0.7 -5.0 Uncharacterized protein required for cytochrome oxidase assembly compare
Ga0059261_0719 -0.7 -3.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_4056 -0.7 -5.3 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Ga0059261_3502 -0.7 -1.9 Fatty acid desaturase compare
Ga0059261_3196 -0.7 -1.6 Transcriptional regulator compare
Ga0059261_3545 -0.7 -1.5 hypothetical protein compare
Ga0059261_4204 -0.7 -2.8 transcriptional regulator, TetR family compare
Ga0059261_2145 -0.7 -3.4 ribosome-binding factor A compare
Ga0059261_2008 -0.7 -6.2 cytochrome c oxidase, subunit I compare
Ga0059261_3128 -0.7 -5.2 capsular exopolysaccharide family compare
Ga0059261_3657 -0.7 -4.0 His Kinase A (phospho-acceptor) domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_2050 -0.7 -2.5 hypothetical protein compare
Ga0059261_2206 -0.7 -4.3 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG compare
Ga0059261_3124 -0.7 -2.6 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Ga0059261_0089 -0.7 -3.0 trigger factor compare
Ga0059261_4054 -0.6 -1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_2179 -0.6 -4.5 Phospholipid N-methyltransferase compare
Ga0059261_2415 -0.6 -5.2 Phytoene/squalene synthetase compare
Ga0059261_2534 -0.6 -2.0 3-hydroxyacyl-CoA dehydrogenase compare
Ga0059261_2540 -0.6 -1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_2021 -0.6 -4.9 Protein of unknown function (DUF2029) compare
Ga0059261_2929 -0.6 -1.5 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_1419 -0.6 -2.5 fructose-6-phosphate aldolase, TalC/MipB family compare
Ga0059261_3347 -0.6 -2.5 Domain of unknown function DUF87 compare
Ga0059261_2352 -0.6 -2.5 hypothetical protein compare
Ga0059261_1768 -0.6 -1.6 Sigma-70 region 2 compare
Ga0059261_1411 -0.6 -5.2 Opacity protein and related surface antigens compare
Ga0059261_1312 -0.6 -2.5 amino acid/peptide transporter (Peptide:H+ symporter), bacterial compare
Ga0059261_2458 -0.6 -3.7 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases compare
Ga0059261_1868 -0.6 -1.6 ABC-type uncharacterized transport system, auxiliary component compare
Ga0059261_1292 -0.6 -1.7 hypothetical protein compare
Ga0059261_0211 -0.6 -3.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_2314 -0.6 -2.2 Protein-disulfide isomerase compare
Ga0059261_0038 -0.6 -2.1 Transcriptional regulators compare
Ga0059261_3581 -0.6 -3.5 Alpha/beta hydrolase family compare
Ga0059261_3286 -0.6 -4.6 Small-conductance mechanosensitive channel compare
Ga0059261_3965 -0.6 -3.6 formimidoylglutamate deiminase (EC 3.5.3.13) compare
Ga0059261_1856 -0.6 -2.1 hypothetical protein compare
Ga0059261_2188 -0.6 -1.5 Uncharacterized conserved protein compare
Ga0059261_2547 -0.6 -0.9 tRNA compare
Ga0059261_2471 -0.6 -1.2 hypothetical protein compare
Ga0059261_1774 -0.6 -1.1 hypothetical protein compare
Ga0059261_4139 -0.6 -1.3 hypothetical protein compare
Ga0059261_2700 -0.5 -4.3 Putative Zn-dependent protease, contains TPR repeats compare
Ga0059261_3220 -0.5 -4.4 Cytochrome b subunit of the bc complex compare
Ga0059261_3209 -0.5 -4.0 queuosine biosynthesis protein QueC compare
Ga0059261_2034 -0.5 -3.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_1908 -0.5 -2.0 Ribonuclease E/G family compare
Ga0059261_0146 -0.5 -1.9 amidohydrolase, PncC family compare
Ga0059261_2286 -0.5 -2.7 Fe2+ transport system protein B compare
Ga0059261_3595 -0.5 -2.3 Site-specific recombinase XerD compare
Ga0059261_0208 -0.5 -2.2 Response regulator receiver domain compare
Ga0059261_3121 -0.5 -3.0 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_3786 -0.5 -2.7 Malic enzyme compare
Ga0059261_2222 -0.5 -3.4 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_0246 -0.5 -0.9 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
Ga0059261_3159 -0.5 -2.0 TolR protein compare
Ga0059261_2247 -0.5 -3.6 Beta-lactamase class A compare
Ga0059261_2266 -0.5 -2.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_2913 -0.5 -1.5 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_1415 -0.5 -2.5 UDP-N-acetylmuramate-alanine ligase compare
Ga0059261_1035 -0.5 -0.9 hypothetical protein compare
Ga0059261_2241 -0.5 -2.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1567 -0.5 -4.0 Arabinose efflux permease compare
Ga0059261_1404 -0.5 -3.0 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_1071 -0.5 -1.8 hypothetical protein compare
Ga0059261_3190 -0.5 -3.9 3-isopropylmalate dehydrogenase compare
Ga0059261_2758 -0.5 -2.8 Uncharacterized membrane-associated protein compare
Ga0059261_0248 -0.5 -2.0 hypothetical protein compare
Ga0059261_1047 -0.5 -2.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Ga0059261_2416 -0.5 -2.8 TIGR00730 family protein compare
Ga0059261_2560 -0.5 -3.5 transcriptional regulator, TetR family compare
Ga0059261_4224 -0.5 -0.9 hypothetical protein compare
Ga0059261_1011 -0.5 -1.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Ga0059261_4214 -0.5 -1.2 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_3214 -0.4 -2.8 hypothetical protein compare
Ga0059261_2285 -0.4 -1.1 Fe2+ transport system protein A compare
Ga0059261_0445 -0.4 -1.8 hypothetical protein compare
Ga0059261_2895 -0.4 -2.5 Type IV secretory pathway, protease TraF compare
Ga0059261_1500 -0.4 -1.8 phosphoadenylylsulfate reductase (thioredoxin) (EC 1.8.4.8) compare
Ga0059261_2506 -0.4 -3.2 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) compare
Ga0059261_0223 -0.4 -1.3 Peptidase inhibitor I78 family compare
Ga0059261_1809 -0.4 -3.1 tRNA synthetases class I (E and Q), catalytic domain compare
Ga0059261_1046 -0.4 -2.8 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Ga0059261_0239 -0.4 -0.8 tryptophan synthase, alpha chain (EC 4.2.1.20) compare
Ga0059261_3105 -0.4 -3.0 Methyltransferase domain compare
Ga0059261_3554 -0.4 -2.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_3621 -0.4 -2.8 FOG: EAL domain compare
Ga0059261_2239 -0.4 -2.6 tRNA and rRNA cytosine-C5-methylases compare
Ga0059261_0472 -0.4 -1.5 Predicted metal-binding protein compare
Ga0059261_0136 -0.4 -1.4 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation compare
Ga0059261_3624 -0.4 -1.5 hypothetical protein compare
Ga0059261_3685 -0.4 -2.7 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_0935 -0.4 -2.0 Uncharacterized conserved protein compare
Ga0059261_1360 -0.4 -3.0 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Ga0059261_3939 -0.4 -1.8 transcriptional regulator, TetR family compare
Ga0059261_4051 -0.4 -1.5 Transcriptional regulator compare
Ga0059261_0946 -0.4 -2.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_1791 -0.4 -1.0 hypothetical protein compare
Ga0059261_1825 -0.4 -2.2 hypothetical protein compare
Ga0059261_0214 -0.4 -3.5 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Ga0059261_0726 -0.4 -1.1 hypothetical protein compare
Ga0059261_2501 -0.4 -2.6 C-terminal peptidase (prc) compare
Ga0059261_3186 -0.4 -2.9 Excinuclease ABC subunit C compare
Ga0059261_2538 -0.4 -3.3 Membrane protein TerC, possibly involved in tellurium resistance compare
Ga0059261_4046 -0.4 -1.0 Response regulator receiver domain compare
Ga0059261_0062 -0.4 -1.6 hypothetical protein compare
Ga0059261_1795 -0.4 -1.6 Predicted nucleoside-diphosphate-sugar epimerases compare
Ga0059261_2568 -0.4 -1.7 P-type conjugative transfer protein TrbJ compare


Specific Phenotypes

For 3 genes in this experiment

For stress Gentamicin sulfate salt in Sphingomonas koreensis DSMZ 15582

For stress Gentamicin sulfate salt across organisms