Experiment set4IT021 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Gentamicin sulfate salt 0.015 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_1939 +0.9 2.3 putative phosphoesterase compare
Ga0059261_3488 +0.8 1.8 Histidine kinase/HAMP domain compare
Ga0059261_1380 +0.8 6.3 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1381 +0.7 3.4 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_3605 +0.6 2.5 tRNA compare
Ga0059261_2086 +0.6 1.3 SAF-like compare
Ga0059261_0411 +0.6 1.9 Uncharacterized conserved protein compare
Ga0059261_1546 +0.5 3.6 MerC mercury resistance protein compare
Ga0059261_3971 +0.5 1.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_3992 +0.5 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_0390 +0.5 0.7 Ribbon-helix-helix protein, copG family compare
Ga0059261_1799 +0.5 1.9 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_4185 +0.5 1.1 hypothetical protein compare
Ga0059261_3451 +0.5 1.1 hypothetical protein compare
Ga0059261_1196 +0.5 1.3 hypothetical protein compare
Ga0059261_2466 +0.5 3.5 DnaJ domain/DnaJ C terminal domain compare
Ga0059261_0084 +0.5 1.8 hypothetical protein compare
Ga0059261_2120 +0.4 1.8 hypothetical protein compare
Ga0059261_3251 +0.4 1.5 Transcriptional regulator compare
Ga0059261_1652 +0.4 1.0 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily compare
Ga0059261_0393 +0.4 1.6 hypothetical protein compare
Ga0059261_3925 +0.4 2.1 Transcriptional regulators compare
Ga0059261_0242 +0.4 1.1 hypothetical protein compare
Ga0059261_3280 +0.4 1.3 Uncharacterized conserved protein compare
Ga0059261_3174 +0.4 2.3 EF hand compare
Ga0059261_2939 +0.4 2.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_3491 +0.4 2.7 hypothetical protein compare
Ga0059261_2552 +0.4 2.4 Phosphotransacetylase compare
Ga0059261_1315 +0.4 1.5 Alpha/beta hydrolase family compare
Ga0059261_2044 +0.4 3.0 peptide chain release factor 3 compare
Ga0059261_1573 +0.4 2.3 hypothetical protein compare
Ga0059261_0050 +0.4 2.0 Predicted membrane protein compare
Ga0059261_4007 +0.4 1.0 Transcriptional regulators compare
Ga0059261_3327 +0.4 2.1 hypothetical protein compare
Ga0059261_1303 +0.4 2.4 hypothetical protein compare
Ga0059261_3598 +0.4 1.7 Flp pilus assembly protein, pilin Flp compare
Ga0059261_3153 +0.4 1.4 Uncharacterized protein conserved in bacteria compare
Ga0059261_3081 +0.4 2.3 Uncharacterized conserved small protein compare
Ga0059261_3997 +0.4 2.1 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Ga0059261_3085 +0.4 1.0 Predicted transcriptional regulators compare
Ga0059261_3807 +0.4 1.9 Uncharacterized conserved protein compare
Ga0059261_0379 +0.4 1.5 DNA binding domain, excisionase family compare
Ga0059261_0045 +0.4 1.6 hypothetical protein compare
Ga0059261_1111 +0.4 2.2 PilZ domain compare
Ga0059261_1311 +0.4 1.8 Nitroreductase compare
Ga0059261_2368 +0.4 1.0 Phage baseplate assembly protein W compare
Ga0059261_2187 +0.4 2.8 Cell Wall Hydrolase compare
Ga0059261_0102 +0.4 2.8 endopeptidase La compare
Ga0059261_0304 +0.4 1.0 Bacterioferritin-associated ferredoxin compare
Ga0059261_1560 +0.4 1.6 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Ga0059261_2462 +0.4 1.8 Predicted transcriptional regulators compare
Ga0059261_3755 +0.4 1.0 Protein of unknown function (DUF2798) compare
Ga0059261_0773 +0.4 1.6 Esterase/lipase compare
Ga0059261_3909 +0.4 1.6 Predicted membrane protein compare
Ga0059261_3569 +0.3 1.2 chaperone protein DnaJ compare
Ga0059261_2347 +0.3 0.9 hypothetical protein compare
Ga0059261_4060 +0.3 1.1 Predicted membrane protein compare
Ga0059261_0817 +0.3 1.7 GTP-binding protein TypA/BipA compare
Ga0059261_0889 +0.3 0.9 Cold shock proteins compare
Ga0059261_2843 +0.3 1.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_1499 +0.3 1.7 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Ga0059261_1485 +0.3 1.7 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Ga0059261_0645 +0.3 1.9 DNA replication and repair protein RecR compare
Ga0059261_0126 +0.3 2.4 hydrolase, TatD family compare
Ga0059261_0973 +0.3 1.5 hypothetical protein compare
Ga0059261_4058 +0.3 2.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_3367 +0.3 1.6 hypothetical protein compare
Ga0059261_1425 +0.3 2.5 Protein of unknown function (DUF1203) compare
Ga0059261_2531 +0.3 1.3 conserved hypothetical integral membrane protein compare
Ga0059261_3926 +0.3 2.8 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Ga0059261_2237 +0.3 2.1 Protein of unknown function (DUF1674) compare
Ga0059261_1396 +0.3 1.5 EF-hand domain pair compare
Ga0059261_3708 +0.3 2.0 GAF domain-containing protein compare
Ga0059261_1262 +0.3 2.6 cobaltochelatase CobS subunit (EC 6.6.1.2) compare
Ga0059261_3430 +0.3 1.1 NADH:ubiquinone oxidoreductase 17.2 kD subunit compare
Ga0059261_1574 +0.3 1.0 Superfamily II DNA and RNA helicases compare
Ga0059261_1962 +0.3 1.1 RNase HII (EC 3.1.26.4) compare
Ga0059261_2980 +0.3 2.7 Outer membrane protein compare
Ga0059261_0060 +0.3 1.2 Uncharacterized conserved protein compare
Ga0059261_0597 +0.3 1.5 hypothetical protein compare
Ga0059261_3056 +0.3 1.3 Protein of unknown function (DUF2958) compare
Ga0059261_2730 +0.3 0.6 Sortase and related acyltransferases compare
Ga0059261_1185 +0.3 0.8 Thiolase, C-terminal domain compare
Ga0059261_2448 +0.3 0.9 DNA protecting protein DprA compare
Ga0059261_0351 +0.3 2.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
Ga0059261_0745 +0.3 1.3 Uncharacterized membrane protein, required for colicin V production compare
Ga0059261_2215 +0.3 0.8 Thiamine monophosphate synthase compare
Ga0059261_2680 +0.3 0.7 hypothetical protein compare
Ga0059261_2618 +0.3 1.2 Protein of unknown function (DUF2721) compare
Ga0059261_2589 +0.3 1.3 Protein of unknown function (DUF2493) compare
Ga0059261_2584 +0.3 2.1 Predicted transcriptional regulators compare
Ga0059261_3604 +0.3 1.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_0656 +0.3 1.1 Predicted dehydrogenases and related proteins compare
Ga0059261_3721 +0.3 1.9 hypothetical protein compare
Ga0059261_3350 +0.3 2.3 Na+/H+-dicarboxylate symporters compare
Ga0059261_0723 +0.3 1.1 hypothetical protein compare
Ga0059261_3752 +0.3 1.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_2987 +0.3 0.9 hypothetical protein compare
Ga0059261_0451 +0.3 1.0 hypothetical protein compare
Ga0059261_0133 +0.3 1.1 GTP-binding protein HflX compare
Ga0059261_2142 +0.3 2.3 tRNA pseudouridine(55) synthase compare
Ga0059261_0448 +0.3 0.4 hypothetical protein compare
Ga0059261_1557 +0.3 1.7 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase compare
Ga0059261_3797 +0.3 2.0 Sel1 repeat compare
Ga0059261_0964 +0.3 1.2 Superfamily II DNA and RNA helicases compare
Ga0059261_1145 +0.3 0.8 flagella basal body P-ring formation protein FlgA compare
Ga0059261_3076 +0.3 1.7 P-type conjugative transfer protein TrbJ compare
Ga0059261_2277 +0.3 0.7 hypothetical protein compare
Ga0059261_2712 +0.3 1.9 Isopenicillin N synthase and related dioxygenases compare
Ga0059261_0720 +0.3 1.0 Predicted small integral membrane protein compare
Ga0059261_3207 +0.3 1.4 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_0141 +0.3 1.2 transcriptional regulator, LysR family compare
Ga0059261_0493 +0.3 0.7 hypothetical protein compare
Ga0059261_4120 +0.3 0.6 Stress responsive A/B Barrel Domain compare
Ga0059261_1213 +0.3 0.9 hypothetical protein compare
Ga0059261_2983 +0.3 1.8 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases compare
Ga0059261_0137 +0.3 1.5 nitrogen regulation protein NR(I) compare
Ga0059261_1188 +0.3 1.8 hypothetical protein compare
Ga0059261_2533 +0.3 1.8 hypothetical protein compare
Ga0059261_0811 +0.3 1.0 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family compare
Ga0059261_3684 +0.3 1.4 hypothetical protein compare
Ga0059261_3132 +0.2 1.1 hypothetical protein compare
Ga0059261_1783 +0.2 1.3 Transposase and inactivated derivatives compare
Ga0059261_3144 +0.2 0.8 Transcriptional regulator compare
Ga0059261_2245 +0.2 1.9 hypothetical protein compare
Ga0059261_0143 +0.2 1.5 hypothetical protein compare
Ga0059261_2052 +0.2 1.3 siroheme synthase, N-terminal domain compare
Ga0059261_3332 +0.2 1.6 Predicted membrane protein compare
Ga0059261_0585 +0.2 1.7 Predicted membrane protein (DUF2306) compare
Ga0059261_0252 +0.2 0.9 SpoIIAA-like compare
Ga0059261_2281 +0.2 1.4 Phytanoyl-CoA dioxygenase (PhyH) compare
Ga0059261_3321 +0.2 1.0 pyrroline-5-carboxylate reductase compare
Ga0059261_0157 +0.2 1.6 AraC-type DNA-binding domain-containing proteins compare
Ga0059261_1732 +0.2 1.0 Flagellar hook capping protein - N-terminal region compare
Ga0059261_3165 +0.2 1.5 PEP phosphonomutase and related enzymes compare
Ga0059261_3886 +0.2 1.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_0974 +0.2 1.7 AraC-type DNA-binding domain-containing proteins compare
Ga0059261_2271 +0.2 1.7 branched-chain alpha-keto acid dehydrogenase E2 component (EC 2.3.1.168) compare
Ga0059261_0724 +0.2 1.6 Acetyltransferase (GNAT) domain compare
Ga0059261_3335 +0.2 0.9 hypothetical protein compare
Ga0059261_4181 +0.2 1.5 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_4240 +0.2 1.5 hypothetical protein compare
Ga0059261_1079 +0.2 1.8 Chemotaxis protein histidine kinase and related kinases compare
Ga0059261_0360 +0.2 1.3 Putative NADH-flavin reductase compare
Ga0059261_3658 +0.2 2.0 hypothetical protein compare
Ga0059261_2436 +0.2 1.4 hypothetical protein compare
Ga0059261_3882 +0.2 1.0 dimethyladenosine transferase (EC 2.1.1.-) compare
Ga0059261_3603 +0.2 1.6 Predicted amidohydrolase compare
Ga0059261_2309 +0.2 1.3 transcriptional regulator, LacI family compare
Ga0059261_3168 +0.2 1.3 peroxiredoxin, OsmC subfamily compare
Ga0059261_2613 +0.2 1.6 AraC-type DNA-binding domain-containing proteins compare
Ga0059261_3772 +0.2 1.1 NIPSNAP compare
Ga0059261_1881 +0.2 1.2 Predicted membrane protein compare
Ga0059261_2593 +0.2 0.9 hypothetical protein compare
Ga0059261_2581 +0.2 0.9 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_0957 +0.2 0.7 Protein of unknown function (DUF2798) compare
Ga0059261_2694 +0.2 0.8 RadC-like JAB domain compare
Ga0059261_0834 +0.2 1.2 hypothetical protein compare
Ga0059261_4030 +0.2 1.3 glutamate N-acetyltransferase (EC 2.3.1.35) compare
Ga0059261_3376 +0.2 1.2 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Ga0059261_3366 +0.2 1.0 hypothetical protein compare
Ga0059261_3562 +0.2 0.8 Glycosyltransferase compare
Ga0059261_1385 +0.2 2.0 Glycosyltransferase compare
Ga0059261_1095 +0.2 1.4 Flagellar motor switch protein compare
Ga0059261_0861 +0.2 1.7 Acyl-CoA dehydrogenases compare
Ga0059261_3139 +0.2 1.3 Predicted membrane protein compare
Ga0059261_3986 +0.2 1.4 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_0191 +0.2 1.3 hypothetical protein compare
Ga0059261_1257 +0.2 1.4 Uncharacterized iron-regulated protein compare
Ga0059261_2156 +0.2 1.5 hypothetical protein compare
Ga0059261_0664 +0.2 0.6 pseudouridine synthase, RluA family compare
Ga0059261_2101 +0.2 0.9 Putative transposase of IS4/5 family (DUF4096) compare
Ga0059261_3407 +0.2 1.6 Superfamily II DNA and RNA helicases compare
Ga0059261_0659 +0.2 0.8 transcriptional regulator, HxlR family compare
Ga0059261_4006 +0.2 1.5 Multidrug resistance efflux pump compare
Ga0059261_3613 +0.2 1.3 Dihydroneopterin aldolase compare
Ga0059261_0849 +0.2 1.3 transcriptional regulator, TetR family compare
Ga0059261_0846 +0.2 1.2 Zn-dependent alcohol dehydrogenases, class III compare
Ga0059261_2273 +0.2 1.9 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit compare
Ga0059261_0980 +0.2 1.1 polyhydroxyalkanoate synthesis repressor PhaR compare
Ga0059261_0807 +0.2 1.0 RNA methyltransferase, RsmE family compare
Ga0059261_0774 +0.2 1.6 Carboxylesterase type B compare
Ga0059261_2262 +0.2 1.6 Predicted acetyltransferase compare
Ga0059261_2231 +0.2 1.1 Uncharacterized conserved protein compare
Ga0059261_2966 +0.2 1.2 2-deoxy-D-gluconate 3-dehydrogenase compare
Ga0059261_2272 +0.2 1.9 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit compare
Ga0059261_0129 +0.2 1.4 MazG family protein compare
Ga0059261_3860 +0.2 1.7 Ku protein, prokaryotic compare
Ga0059261_1786 +0.2 1.2 hypothetical protein compare
Ga0059261_1497 +0.2 1.2 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
Ga0059261_2826 +0.2 1.4 transcriptional regulator, TetR family compare
Ga0059261_2981 +0.2 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_2126 +0.2 1.0 ETC complex I subunit conserved region compare
Ga0059261_0551 +0.2 0.8 Cytochrome c2 compare
Ga0059261_0907 +0.2 1.2 Predicted transcriptional regulators compare
Ga0059261_4032 +0.2 1.1 Sensors of blue-light using FAD compare
Ga0059261_2952 +0.2 1.0 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_4011 +0.2 1.0 hypothetical protein compare
Ga0059261_0344 +0.2 0.8 Molecular chaperone (small heat shock protein) compare
Ga0059261_1258 +0.2 1.9 TonB-dependent siderophore receptor compare


Specific Phenotypes

For 3 genes in this experiment

For stress Gentamicin sulfate salt in Sphingomonas koreensis DSMZ 15582

For stress Gentamicin sulfate salt across organisms