Experiment set4IT019 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Nalidixic acid sodium salt 0.05 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_3939 +2.3 15.0 transcriptional regulator, TetR family compare
Ga0059261_3938 +2.2 15.7 Imidazolonepropionase and related amidohydrolases compare
Ga0059261_3937 +2.0 15.6 Imidazolonepropionase and related amidohydrolases compare
Ga0059261_0242 +0.8 2.3 hypothetical protein compare
Ga0059261_3807 +0.7 4.3 Uncharacterized conserved protein compare
Ga0059261_1911 +0.7 1.7 Thioredoxin-like proteins and domains compare
Ga0059261_2391 +0.7 1.8 Helix-turn-helix domain compare
Ga0059261_0811 +0.7 2.0 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family compare
Ga0059261_3569 +0.7 1.8 chaperone protein DnaJ compare
Ga0059261_3604 +0.7 2.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1092 +0.7 2.3 flagellar motor switch protein FliN compare
Ga0059261_3488 +0.6 1.3 Histidine kinase/HAMP domain compare
Ga0059261_0083 +0.6 1.2 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_2618 +0.6 1.9 Protein of unknown function (DUF2721) compare
Ga0059261_3227 +0.6 1.4 GTP-binding protein YchF compare
Ga0059261_3638 +0.5 1.1 Predicted integral membrane protein (DUF2282) compare
Ga0059261_3598 +0.5 2.5 Flp pilus assembly protein, pilin Flp compare
Ga0059261_0237 +0.5 2.1 phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Ga0059261_1315 +0.5 2.3 Alpha/beta hydrolase family compare
Ga0059261_0102 +0.5 3.9 endopeptidase La compare
Ga0059261_0304 +0.5 1.5 Bacterioferritin-associated ferredoxin compare
Ga0059261_2076 +0.5 0.9 hypothetical protein compare
Ga0059261_2347 +0.5 1.6 hypothetical protein compare
Ga0059261_3027 +0.5 2.3 Predicted transcriptional regulators compare
Ga0059261_1527 +0.5 1.0 hypothetical protein compare
Ga0059261_3579 +0.5 2.7 hypothetical protein compare
Ga0059261_2381 +0.5 3.1 Phage head completion protein (GPL) compare
Ga0059261_0060 +0.5 2.0 Uncharacterized conserved protein compare
Ga0059261_1538 +0.5 2.3 Predicted transcriptional regulators compare
Ga0059261_3492 +0.5 2.7 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3100 +0.5 3.6 Sugar transferases involved in lipopolysaccharide synthesis compare
Ga0059261_3411 +0.5 3.1 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3451 +0.5 1.1 hypothetical protein compare
Ga0059261_1756 +0.5 1.5 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes compare
Ga0059261_3556 +0.5 1.7 transcriptional regulator, TetR family compare
Ga0059261_1847 +0.4 2.2 hypothetical protein compare
Ga0059261_1962 +0.4 1.3 RNase HII (EC 3.1.26.4) compare
Ga0059261_3026 +0.4 0.9 Cation efflux family compare
Ga0059261_0720 +0.4 1.7 Predicted small integral membrane protein compare
Ga0059261_0354 +0.4 1.4 6-phosphogluconate dehydratase (EC 4.2.1.12) compare
Ga0059261_3992 +0.4 1.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_2063 +0.4 1.8 Flagellar biosynthesis protein, FliO compare
Ga0059261_1263 +0.4 2.1 hypothetical protein compare
Ga0059261_3129 +0.4 3.0 SLBB domain/Polysaccharide biosynthesis/export protein compare
Ga0059261_3435 +0.4 2.7 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3491 +0.4 2.6 hypothetical protein compare
Ga0059261_1762 +0.4 1.0 hypothetical protein compare
Ga0059261_3800 +0.4 1.8 Cold shock proteins compare
Ga0059261_1265 +0.4 1.4 hypothetical protein compare
Ga0059261_0586 +0.4 2.0 hypothetical protein compare
Ga0059261_0252 +0.4 1.4 SpoIIAA-like compare
Ga0059261_0344 +0.4 1.6 Molecular chaperone (small heat shock protein) compare
Ga0059261_1513 +0.4 2.3 hypothetical protein compare
Ga0059261_3367 +0.4 2.0 hypothetical protein compare
Ga0059261_0059 +0.4 1.2 Stress-induced morphogen (activity unknown) compare
Ga0059261_0276 +0.4 1.7 Protein required for attachment to host cells compare
Ga0059261_2736 +0.4 2.1 hypothetical protein compare
Ga0059261_0685 +0.4 0.7 pyruvate kinase compare
Ga0059261_2914 +0.4 1.5 Type IV secretory pathway, TrbD component compare
Ga0059261_3153 +0.4 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_3430 +0.4 1.1 NADH:ubiquinone oxidoreductase 17.2 kD subunit compare
Ga0059261_2365 +0.4 1.5 Mu-like prophage FluMu protein gp41 compare
Ga0059261_0920 +0.4 1.8 rRNA methylases compare
Ga0059261_0690 +0.4 0.9 Acetyltransferases compare
Ga0059261_1425 +0.4 2.5 Protein of unknown function (DUF1203) compare
Ga0059261_0926 +0.4 1.7 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Ga0059261_3161 +0.3 2.3 tol-pal system-associated acyl-CoA thioesterase compare
Ga0059261_0817 +0.3 2.1 GTP-binding protein TypA/BipA compare
Ga0059261_2466 +0.3 2.7 DnaJ domain/DnaJ C terminal domain compare
Ga0059261_1795 +0.3 1.5 Predicted nucleoside-diphosphate-sugar epimerases compare
Ga0059261_3038 +0.3 1.7 hypothetical protein compare
Ga0059261_3052 +0.3 1.8 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_2939 +0.3 2.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_0816 +0.3 1.1 hypothetical protein compare
Ga0059261_2145 +0.3 1.9 ribosome-binding factor A compare
Ga0059261_0980 +0.3 2.2 polyhydroxyalkanoate synthesis repressor PhaR compare
Ga0059261_2215 +0.3 0.8 Thiamine monophosphate synthase compare
Ga0059261_1831 +0.3 0.9 hypothetical protein compare
Ga0059261_3684 +0.3 1.7 hypothetical protein compare
Ga0059261_0872 +0.3 2.4 Signal transduction histidine kinase compare
Ga0059261_2570 +0.3 1.3 Type IV secretory pathway, TrbD component compare
Ga0059261_4046 +0.3 1.0 Response regulator receiver domain compare
Ga0059261_2229 +0.3 1.1 Predicted transcriptional regulators compare
Ga0059261_3708 +0.3 1.4 GAF domain-containing protein compare
Ga0059261_3755 +0.3 0.9 Protein of unknown function (DUF2798) compare
Ga0059261_4060 +0.3 0.6 Predicted membrane protein compare
Ga0059261_0014 +0.3 2.2 phosphopyruvate hydratase compare
Ga0059261_2120 +0.3 1.1 hypothetical protein compare
Ga0059261_1904 +0.3 1.0 Asparaginase compare
Ga0059261_0773 +0.3 1.7 Esterase/lipase compare
Ga0059261_3127 +0.3 1.9 hypothetical protein compare
Ga0059261_1022 +0.3 1.4 hypothetical protein compare
Ga0059261_2090 +0.3 1.6 flagellar basal-body rod protein FlgC compare
Ga0059261_1881 +0.3 1.5 Predicted membrane protein compare
Ga0059261_0494 +0.3 1.1 ABC-type antimicrobial peptide transport system, ATPase component compare
Ga0059261_0659 +0.3 1.2 transcriptional regulator, HxlR family compare
Ga0059261_4007 +0.3 0.7 Transcriptional regulators compare
Ga0059261_1612 +0.3 0.7 hypothetical protein compare
Ga0059261_0628 +0.3 1.5 L-threonine O-3-phosphate decarboxylase (EC 4.1.1.81) compare
Ga0059261_0208 +0.3 0.9 Response regulator receiver domain compare
Ga0059261_0656 +0.3 1.1 Predicted dehydrogenases and related proteins compare
Ga0059261_3407 +0.3 2.1 Superfamily II DNA and RNA helicases compare
Ga0059261_3784 +0.3 2.3 DNA mismatch repair protein MutS compare
Ga0059261_0028 +0.3 1.3 Predicted transcriptional regulators compare
Ga0059261_2663 +0.3 0.6 Domain of unknown function (DUF718) compare
Ga0059261_2735 +0.3 1.2 Glyoxalase-like domain compare
Ga0059261_2360 +0.3 2.4 Uncharacterised protein family UPF0547 compare
Ga0059261_0734 +0.3 2.2 RNA compare
Ga0059261_1803 +0.3 1.6 Domain of unknown function (DUF4136) compare
Ga0059261_1188 +0.3 2.1 hypothetical protein compare
Ga0059261_3622 +0.3 1.7 hypothetical protein compare
Ga0059261_3210 +0.3 1.0 Organic radical activating enzymes compare
Ga0059261_3285 +0.3 1.2 Acyl dehydratase compare
Ga0059261_1109 +0.3 1.5 Flagellar biosynthesis protein, FliO compare
Ga0059261_2362 +0.3 2.4 Phage protein D compare
Ga0059261_0983 +0.3 2.6 TonB dependent receptor/TonB-dependent Receptor Plug Domain compare
Ga0059261_0963 +0.3 1.3 hypothetical protein compare
Ga0059261_1285 +0.3 2.0 Uncharacterized conserved protein compare
Ga0059261_1928 +0.3 1.4 Predicted permeases compare
Ga0059261_3356 +0.3 0.5 hypothetical protein compare
Ga0059261_2277 +0.3 0.8 hypothetical protein compare
Ga0059261_0585 +0.3 1.7 Predicted membrane protein (DUF2306) compare
Ga0059261_4204 +0.3 1.3 transcriptional regulator, TetR family compare
Ga0059261_0203 +0.3 1.5 FKBP-type peptidyl-prolyl cis-trans isomerase compare
Ga0059261_2795 +0.3 1.6 Predicted metal-dependent hydrolase of the TIM-barrel fold compare
Ga0059261_1733 +0.3 1.8 hypothetical protein compare
Ga0059261_1286 +0.3 1.7 phasin family protein compare
Ga0059261_0893 +0.3 1.4 inosine-5'-monophosphate dehydrogenase compare
Ga0059261_1774 +0.3 0.5 hypothetical protein compare
Ga0059261_2670 +0.3 1.9 Predicted kinase compare
Ga0059261_2372 +0.3 2.3 Phage-related lysozyme (muraminidase) compare
Ga0059261_2294 +0.3 0.4 Cell division protein compare
Ga0059261_3961 +0.3 2.3 Urocanate hydratase (EC 4.2.1.49) (from data) compare
Ga0059261_2367 +0.3 2.2 Phage tail sheath protein FI compare
Ga0059261_0360 +0.3 1.6 Putative NADH-flavin reductase compare
Ga0059261_2420 +0.3 1.1 transcriptional regulator, TetR family compare
Ga0059261_1335 +0.3 1.2 Predicted ATPase compare
Ga0059261_2378 +0.3 0.8 phage virion morphogenesis (putative tail completion) protein compare
Ga0059261_2913 +0.3 0.8 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_3382 +0.3 1.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_4059 +0.3 1.5 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Ga0059261_3882 +0.3 0.6 dimethyladenosine transferase (EC 2.1.1.-) compare
Ga0059261_0199 +0.3 1.4 hypothetical protein compare
Ga0059261_1351 +0.3 2.1 signal peptide peptidase SppA, 67K type compare
Ga0059261_2097 +0.3 1.0 Rod binding protein compare
Ga0059261_1407 +0.3 2.2 23S rRNA (adenine(2503)-C(2))-methyltransferase compare
Ga0059261_3059 +0.3 1.7 Uncharacterized conserved protein compare
Ga0059261_0245 +0.3 0.7 pseudouridine synthase compare
Ga0059261_2448 +0.3 0.5 DNA protecting protein DprA compare
Ga0059261_0802 +0.3 1.0 protein-export chaperone SecB compare
Ga0059261_1570 +0.3 1.8 N-formylglutamate amidohydrolase compare
Ga0059261_0766 +0.3 1.5 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_1562 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_3669 +0.2 2.0 Beta-lactamase class C and other penicillin binding proteins compare
Ga0059261_1333 +0.2 1.8 Zn-dependent hydrolases, including glyoxylases compare
Ga0059261_1767 +0.2 2.0 Helix-turn-helix domain/DNA N-6-adenine-methyltransferase (Dam)/Helix-turn-helix compare
Ga0059261_1746 +0.2 1.2 transcriptional regulator, AlpA family compare
Ga0059261_2154 +0.2 1.2 uncharacterized domain 1 compare
Ga0059261_0549 +0.2 1.7 Domain of Unknown Function (DUF1080) compare
Ga0059261_3962 +0.2 1.8 N-formylglutamate deformylase (EC 3.5.1.68) (from data) compare
Ga0059261_3947 +0.2 0.6 type II secretion system protein I (GspI) compare
Ga0059261_3097 +0.2 1.2 Calcineurin-like phosphoesterase compare
Ga0059261_3315 +0.2 1.7 Predicted metal-dependent hydrolase with the TIM-barrel fold compare
Ga0059261_0045 +0.2 0.7 hypothetical protein compare
Ga0059261_1021 +0.2 0.9 hypothetical protein compare
Ga0059261_1958 +0.2 0.9 Transcriptional regulators compare
Ga0059261_0631 +0.2 1.1 adenosylcobinamide kinase (EC 2.7.1.156)/adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Ga0059261_1507 +0.2 0.8 deoxycytidine triphosphate deaminase compare
Ga0059261_0633 +0.2 0.8 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Ga0059261_0898 +0.2 0.9 Membrane protein implicated in regulation of membrane protease activity compare
Ga0059261_2267 +0.2 1.9 Predicted Rossmann fold nucleotide-binding protein compare
Ga0059261_2361 +0.2 1.0 Staphylococcal nuclease homologue compare
Ga0059261_2384 +0.2 1.7 Phage capsid scaffolding protein (GPO) serine peptidase compare
Ga0059261_1078 +0.2 0.5 Response regulator receiver domain compare
Ga0059261_3825 +0.2 1.1 thiol reductant ABC exporter, CydD subunit compare
Ga0059261_0174 +0.2 0.5 hypothetical protein compare
Ga0059261_0988 +0.2 1.6 Uncharacterized FAD-dependent dehydrogenases compare
Ga0059261_3606 +0.2 1.2 Transcription elongation factor compare
Ga0059261_3635 +0.2 1.1 Predicted integral membrane protein compare
Ga0059261_2868 +0.2 1.7 Acyl dehydratase compare
Ga0059261_2366 +0.2 1.6 phage contractile tail tube protein, P2 family compare
Ga0059261_2843 +0.2 1.2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_3659 +0.2 1.1 PqqD family protein, HPr-rel-A system compare
Ga0059261_1174 +0.2 1.2 Putative transposase of IS4/5 family (DUF4096) compare
Ga0059261_0812 +0.2 0.9 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_2768 +0.2 0.7 hypothetical protein compare
Ga0059261_3909 +0.2 0.9 Predicted membrane protein compare
Ga0059261_4140 +0.2 1.0 hypothetical protein compare
Ga0059261_0464 +0.2 0.5 hypothetical protein compare
Ga0059261_0525 +0.2 0.6 Transcriptional regulator compare
Ga0059261_2056 +0.2 1.7 Predicted acyl-CoA transferases/carnitine dehydratase compare
Ga0059261_0911 +0.2 1.0 Domain of unknown function (DUF3597) compare
Ga0059261_4161 +0.2 1.6 Predicted phosphoesterase compare
Ga0059261_3381 +0.2 1.1 Arabinose efflux permease compare
Ga0059261_1414 +0.2 1.3 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF compare
Ga0059261_1394 +0.2 1.6 putative efflux protein, MATE family compare
Ga0059261_1035 +0.2 0.4 hypothetical protein compare
Ga0059261_2377 +0.2 1.8 Phage-related baseplate assembly protein compare
Ga0059261_3621 +0.2 1.6 FOG: EAL domain compare
Ga0059261_0535 +0.2 1.5 PAP2 superfamily compare


Specific Phenotypes

For 2 genes in this experiment

For stress Nalidixic acid sodium salt in Sphingomonas koreensis DSMZ 15582

For stress Nalidixic acid sodium salt across organisms