Experiment set4IT013 for Shewanella loihica PV-4

Compare to:

LB with Choline chloride 200 mM

200 most important genes:

  gene name fitness t score description  
Shew_0544 tolC -7.3 -2.7 outer membrane channel protein (RefSeq) compare
Shew_0623 -6.4 -1.0 phage shock protein A, PspA (RefSeq) compare
Shew_2174 -6.2 -1.0 fatty acid metabolism regulator (RefSeq) compare
Shew_3714 -5.9 -2.5 DNA polymerase I (RefSeq) compare
Shew_2075 ruvB -5.8 -1.8 Holliday junction DNA helicase B (RefSeq) compare
Shew_0565 -5.6 -1.7 tRNA delta(2)-isopentenylpyrophosphate transferase (RefSeq) compare
Shew_2473 -5.5 -1.7 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_0566 -5.5 -0.8 RNA chaperone Hfq (RefSeq) compare
Shew_2892 -5.3 -3.8 major facilitator transporter (RefSeq) compare
Shew_2895 -5.3 -5.5 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_1559 -5.3 -0.8 hypothetical protein (RefSeq) compare
Shew_2696 -5.2 -4.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_1602 -5.2 -1.7 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_1861 -5.1 -4.2 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin (RefSeq) compare
Shew_1601 -5.0 -1.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1227 -4.9 -1.1 glutamate--cysteine ligase (RefSeq) compare
Shew_0970 -4.9 -5.0 XRE family transcriptional regulator (RefSeq) compare
Shew_1215 recA -4.9 -2.0 recombinase A (RefSeq) compare
Shew_1058 -4.8 -4.7 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_2476 -4.8 -1.8 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_1403 -4.7 -14.1 dTDP-4-dehydrorhamnose reductase (RefSeq) compare
Shew_2077 -4.6 -2.8 crossover junction endodeoxyribonuclease RuvC (RefSeq) compare
Shew_1152 -4.6 -1.0 MscS mechanosensitive ion channel (RefSeq) compare
Shew_3520 -4.5 -11.2 hypothetical protein (RefSeq) compare
Shew_3499 -4.4 -3.2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_3660 -4.3 -24.1 glutathione reductase (RefSeq) compare
Shew_0383 -4.3 -6.0 malate dehydrogenase (RefSeq) compare
Shew_3522 -4.1 -1.3 hypothetical protein (RefSeq) compare
Shew_2906 -3.9 -1.9 hypothetical protein (RefSeq) compare
Shew_0568 -3.9 -8.4 HflK protein (RefSeq) compare
Shew_3630 -3.8 -1.4 bioH protein (RefSeq) compare
Shew_1404 -3.8 -20.7 dTDP-4-dehydrorhamnose 3,5-epimerase (RefSeq) compare
Shew_0770 -3.8 -6.4 tyrosine recombinase XerD (RefSeq) compare
Shew_0216 -3.7 -0.8 DNA adenine methylase (RefSeq) compare
Shew_3225 -3.7 -4.9 glutathione synthetase (RefSeq) compare
Shew_0031 -3.7 -14.4 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0032 -3.7 -13.2 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) compare
Shew_0567 -3.6 -4.5 GTP-binding protein, HSR1-related (RefSeq) compare
Shew_1544 -3.6 -5.8 TetR family transcriptional regulator (RefSeq) compare
Shew_3507 -3.6 -7.1 ATP-dependent DNA helicase RecG (RefSeq) compare
Shew_0622 -3.6 -3.5 hypothetical protein (RefSeq) compare
Shew_3446 -3.5 -6.4 peptidase M23B (RefSeq) compare
Shew_3807 -3.5 -5.4 peptidase M23B (RefSeq) compare
Shew_0569 -3.5 -1.8 HflC protein (RefSeq) compare
Shew_3117 -3.4 -3.0 predicted chromosome partitioning protein (with smc-like Shew_3118) (from data) compare
Shew_3144 -3.4 -9.0 UDP-N-acetylmuramate (RefSeq) compare
Shew_0459 -3.3 -3.4 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_3604 -3.3 -11.1 hypothetical protein (RefSeq) compare
Shew_2907 -3.3 -3.3 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_3434 -3.2 -18.0 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) compare
Shew_3116 -3.2 -9.6 predicted chromosome partitioning protein (with smc-like Shew_3118) (from data) compare
Shew_2083 -3.0 -4.4 hypothetical protein (RefSeq) compare
Shew_1688 -3.0 -11.4 TonB-dependent receptor (RefSeq) compare
Shew_0777 -2.9 -1.3 two-component response regulator (RefSeq) compare
Shew_3118 -2.9 -19.4 smc-like chromosome partitioning protein (DUF3584) (from data) compare
Shew_1422 -2.9 -1.5 sulfate adenylyltransferase subunit 2 (RefSeq) compare
Shew_3385 uvrD -2.9 -6.5 DNA-dependent helicase II (RefSeq) compare
Shew_2410 -2.8 -0.6 beta-ketoacyl synthase (RefSeq) compare
Shew_0550 -2.8 -2.7 L-sorbosone dehydrogenase, putative (RefSeq) compare
Shew_2085 -2.8 -9.1 alpha-L-glutamate ligase-like protein (RefSeq) compare
Shew_0003 -2.8 -3.8 DNA replication and repair protein RecF (RefSeq) compare
Shew_3691 -2.8 -0.9 hypothetical protein (RefSeq) compare
Shew_3867 -2.8 -7.0 hypothetical protein (RefSeq) compare
Shew_3805 -2.8 -8.6 rhodanese domain-containing protein (RefSeq) compare
Shew_0666 -2.7 -7.7 sulfite reductase subunit beta (RefSeq) compare
Shew_0866 -2.7 -0.9 arginine repressor (RefSeq) compare
Shew_3498 rpoZ -2.6 -2.6 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_0325 -2.5 -2.4 tyrosine recombinase XerC (RefSeq) compare
Shew_1528 -2.5 -2.3 OmpA domain-containing protein (RefSeq) compare
Shew_1050 -2.5 -5.4 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_1028 -2.5 -8.8 hypothetical protein (RefSeq) compare
Shew_3701 -2.5 -7.0 hypothetical protein (RefSeq) compare
Shew_2173 -2.4 -1.7 hypothetical protein (RefSeq) compare
Shew_2926 -2.4 -2.4 CBS domain-containing protein (RefSeq) compare
Shew_2498 -2.4 -1.1 extracellular solute-binding protein (RefSeq) compare
Shew_2775 -2.4 -4.5 MATE efflux family protein (RefSeq) compare
Shew_3618 -2.4 -2.7 general secretory pathway protein E (RefSeq) compare
Shew_2000 -2.3 -1.9 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_1524 -2.3 -6.4 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_0531 -2.3 -4.1 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_3605 -2.3 -1.2 cell division ATP-binding protein FtsE (RefSeq) compare
Shew_1815 -2.2 -1.3 hypothetical protein (RefSeq) compare
Shew_1611 sbcB -2.2 -5.2 exonuclease I (RefSeq) compare
Shew_0618 -2.2 -1.4 hypothetical protein (RefSeq) compare
Shew_1298 guaA -2.2 -9.7 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1505 -2.2 -5.7 hypothetical protein (RefSeq) compare
Shew_1056 -2.1 -3.9 DNA repair protein RecO (RefSeq) compare
Shew_1531 grxA -2.1 -3.1 glutaredoxin 1 (RefSeq) compare
Shew_1400 -2.1 -1.7 lipopolysaccharide biosynthesis protein (RefSeq) compare
Shew_1723 -2.1 -2.9 heat shock protein HtpX (RefSeq) compare
Shew_1136 -2.1 -5.2 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) compare
Shew_1212 -2.1 -3.9 peptidase M23B (RefSeq) compare
Shew_3521 -2.0 -4.1 tryptophan halogenase (RefSeq) compare
Shew_1004 -2.0 -5.1 undecaprenyl pyrophosphate phosphatase (RefSeq) compare
Shew_2504 -2.0 -5.2 PpiC-type peptidyl-prolyl cis-trans isomerase (RefSeq) compare
Shew_1716 -2.0 -2.0 3-beta hydroxysteroid dehydrogenase/isomerase (RefSeq) compare
Shew_3247 -2.0 -0.8 hypothetical protein (RefSeq) compare
Shew_2656 -2.0 -6.5 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_3336 -2.0 -1.4 MarR family transcriptional regulator (RefSeq) compare
Shew_1200 -2.0 -4.3 hybrid sensory histidine kinase BarA (RefSeq) compare
Shew_1526 -1.9 -2.7 TolA family protein (RefSeq) compare
Shew_1922 -1.9 -3.6 phosphoglucomutase (RefSeq) compare
Shew_1810 -1.9 -4.0 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_0136 -1.9 -9.2 stearoyl-CoA 9-desaturase (RefSeq) conserved
Shew_3708 -1.9 -9.6 TetR family transcriptional regulator (RefSeq) compare
Shew_3612 -1.9 -2.3 general secretion pathway protein K (RefSeq) compare
Shew_2666 -1.9 -8.8 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_2233 -1.9 -1.0 recombination protein RecR (RefSeq) compare
Shew_0140 -1.8 -9.1 RNP-1-like RNA-binding protein (RefSeq) compare
Shew_2665 -1.8 -12.5 beta-ketoacyl synthase (RefSeq) compare
Shew_3593 -1.8 -8.2 hypothetical protein (RefSeq) compare
Shew_1523 -1.8 -3.1 4-hydroxybenzoyl-CoA thioesterase (RefSeq) compare
Shew_0665 -1.8 -7.3 sulfite reductase (NADPH) flavoprotein, alpha chain (RefSeq) compare
Shew_2962 -1.8 -4.2 malate dehydrogenase (RefSeq) compare
Shew_1932 cls -1.8 -4.9 cardiolipin synthetase (RefSeq) compare
Shew_1423 -1.8 -1.6 sulfate adenylyltransferase, large subunit (RefSeq) compare
Shew_3620 -1.8 -3.4 general secretion pathway protein C (RefSeq) compare
Shew_2332 -1.8 -2.1 siroheme synthase (RefSeq) compare
Shew_2013 -1.7 -0.8 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_1514 upp -1.7 -2.7 uracil phosphoribosyltransferase (RefSeq) compare
Shew_1211 -1.7 -4.1 protein-L-isoaspartate O-methyltransferase (RefSeq) compare
Shew_3607 -1.7 -6.4 putative methyltransferase (RefSeq) compare
Shew_0284 -1.7 -5.2 hypothetical protein (RefSeq) compare
Shew_1424 -1.7 -6.6 TrkA domain-containing protein (RefSeq) compare
Shew_1606 -1.7 -1.0 hypothetical protein (RefSeq) compare
Shew_2184 -1.6 -1.6 septum site-determining protein MinC (RefSeq) compare
Shew_2668 -1.6 -7.8 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_2585 -1.6 -8.8 histone family protein nucleoid-structuring protein H-NS (RefSeq) compare
Shew_3325 -1.6 -9.7 major facilitator transporter (RefSeq) compare
Shew_1407 -1.6 -9.2 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_3611 -1.6 -0.8 general secretion pathway protein L (RefSeq) compare
Shew_0698 -1.6 -5.0 Na+/H+ antiporter NhaC (RefSeq) compare
Shew_0667 -1.6 -3.1 phosphoadenosine phosphosulfate reductase (RefSeq) compare
Shew_3224 -1.6 -3.2 hypothetical protein (RefSeq) compare
Shew_2327 -1.6 -0.9 hypothetical protein (RefSeq) compare
Shew_1093 -1.5 -3.1 hypothetical protein (RefSeq) compare
Shew_3440 -1.5 -2.1 prepilin peptidase (RefSeq) compare
Shew_0848 -1.5 -0.8 hypothetical protein (RefSeq) compare
Shew_2664 -1.5 -4.1 transcriptional regulator, putative (RefSeq) compare
Shew_0343 -1.5 -1.2 hypothetical protein (RefSeq) compare
Shew_3619 -1.5 -3.4 general secretion pathway protein D (RefSeq) compare
Shew_1427 -1.5 -2.7 3'(2'),5'-bisphosphate nucleotidase (RefSeq) compare
Shew_1713 -1.5 -2.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1156 -1.5 -1.2 hypothetical protein (RefSeq) compare
Shew_2667 -1.5 -8.9 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_2229 -1.5 -1.6 ferrochelatase (RefSeq) compare
Shew_3430 -1.5 -1.3 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1289 -1.4 -1.6 hypothetical protein (RefSeq) compare
Shew_2736 -1.4 -6.2 MarR family transcriptional regulator (RefSeq) compare
Shew_1529 -1.4 -3.3 TPR repeat-containing protein (RefSeq) compare
Shew_0728 -1.4 -5.1 dihydroorotase (RefSeq) compare
Shew_0097 -1.4 -4.1 two component transcriptional regulator (RefSeq) compare
Shew_0441 -1.4 -6.1 dehydratase (RefSeq) compare
Shew_0533 -1.4 -9.2 excinuclease ABC, A subunit (RefSeq) compare
Shew_1730 -1.3 -0.9 hypothetical protein (RefSeq) compare
Shew_0450 -1.3 -4.2 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_1433 -1.3 -6.1 UDP-glucose 4-epimerase (RefSeq) compare
Shew_1384 -1.3 -2.2 response regulator receiver protein (RefSeq) compare
Shew_1288 -1.3 -1.3 type IV pilus biogenesis/stability protein PilW (RefSeq) compare
Shew_0741 -1.3 -1.4 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_1714 -1.3 -2.1 alpha/beta hydrolase fold (RefSeq) compare
Shew_3431 aceE -1.3 -6.2 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_2337 tgt -1.3 -3.3 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_0659 -1.2 -1.7 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) compare
Shew_2434 -1.2 -1.8 hypothetical protein (RefSeq) compare
Shew_3339 -1.2 -1.2 glutathione-dependent formaldehyde-activating, GFA (RefSeq) compare
Shew_3853 -1.2 -7.0 parB-like partition protein (RefSeq) compare
Shew_2146 -1.2 -2.8 hypothetical protein (RefSeq) compare
Shew_3432 pdhR -1.2 -1.8 transcriptional regulator PdhR (RefSeq) compare
Shew_0228 -1.2 -3.5 uroporphyrin-III C/tetrapyrrole methyltransferase (RefSeq) compare
Shew_0098 -1.2 -5.5 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0197 -1.2 -1.0 hypothetical protein (RefSeq) compare
Shew_3223 -1.2 -1.5 deoxyribonuclease I (RefSeq) compare
Shew_1465 -1.2 -1.1 hypothetical protein (RefSeq) compare
Shew_3863 -1.2 -5.0 ATPase central domain-containing protein (RefSeq) compare
Shew_0457 -1.2 -6.1 ATP-dependent helicase HepA (RefSeq) compare
Shew_3702 -1.2 -2.2 glycosyl transferase family protein (RefSeq) compare
Shew_2246 -1.2 -1.7 pseudouridine synthase (RefSeq) compare
Shew_3609 -1.1 -2.6 type II secretion system protein N (RefSeq) compare
Shew_0275 -1.1 -1.4 tetraheme cytochrome c, putative (RefSeq) compare
Shew_2185 -1.1 -3.6 septum site-determining protein MinD (RefSeq) compare
Shew_2558 -1.1 -2.1 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_3313 -1.1 -1.4 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shew_1411 -1.1 -7.0 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_2213 -1.1 -1.8 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (RefSeq) compare
Shew_0384 -1.1 -5.2 regulatory protein CsrD (RefSeq) compare
Shew_2556 -1.1 -1.9 acyl-CoA thioesterase II (RefSeq) compare
Shew_3613 -1.1 -2.2 general secretion pathway protein J (RefSeq) compare
Shew_2060 -1.1 -0.8 pyridoxal-5'-phosphate-dependent enzyme, beta subunit (RefSeq) compare
Shew_3527 -1.1 -1.5 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_2900 -1.1 -2.9 hypothetical protein (RefSeq) compare
Shew_2509 tig -1.1 -3.9 trigger factor (RefSeq) compare
Shew_1951 -1.1 -2.7 aromatic amino acid aminotransferase (RefSeq) compare
Shew_2899 -1.1 -2.5 glutathione synthetase (RefSeq) compare
Shew_2167 -1.1 -1.4 hypothetical protein (RefSeq) compare
Shew_0945 -1.1 -2.0 hypothetical protein (RefSeq) compare
Shew_1825 uvrC -1.0 -3.4 excinuclease ABC subunit C (RefSeq) compare
Shew_1386 -1.0 -2.7 CheA signal transduction histidine kinase (RefSeq) compare
Shew_1511 -1.0 -1.8 UMP phosphatase (RefSeq) compare
Shew_3610 -1.0 -0.5 general secretion pathway M protein (RefSeq) compare


Specific Phenotypes

For 6 genes in this experiment

For stress Choline chloride in Shewanella loihica PV-4

For stress Choline chloride across organisms