Experiment set4IT011 for Shewanella loihica PV-4

Compare to:

LB with 1-ethyl-3-methylimidazolium lysine 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_1298 guaA +7.5 57.7 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_0618 +6.9 11.0 hypothetical protein (RefSeq) compare
Shew_3311 +6.6 31.5 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3560 +6.6 30.3 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_3554 glnA +6.5 10.7 glutamine synthetase (RefSeq) compare
Shew_3561 +6.4 32.6 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_2637 +6.3 33.6 PII uridylyl-transferase (RefSeq) compare
Shew_2572 +5.8 19.4 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1224 +5.5 45.0 sodium:dicarboxylate symporter (RefSeq) compare
Shew_0867 +5.3 6.3 malate dehydrogenase (RefSeq) compare
Shew_3412 purH +5.2 21.1 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) compare
Shew_1058 +4.6 19.6 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_1819 +4.5 10.5 GntR family transcriptional regulator (RefSeq) compare
Shew_0296 +4.3 4.1 heat shock protein Hsp20 (RefSeq) compare
Shew_3377 +4.2 3.5 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_2382 +4.2 28.9 cysteine synthase A (RefSeq) compare
Shew_1341 +4.1 8.8 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_2770 +4.0 3.0 polyprenyl synthetase (RefSeq) compare
Shew_3378 +4.0 7.2 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_3487 pyrE +4.0 18.0 orotate phosphoribosyltransferase (RefSeq) compare
Shew_2000 +3.9 4.9 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_0571 +3.8 8.7 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_2498 +3.8 4.3 extracellular solute-binding protein (RefSeq) compare
Shew_3488 +3.8 6.0 ribonuclease PH (RefSeq) compare
Shew_1128 +3.8 23.6 LysR family transcriptional regulator (RefSeq) compare
Shew_0570 +3.7 5.2 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_0755 +3.7 12.2 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_1301 +3.6 25.3 phosphoribosylformylglycinamidine synthase (RefSeq) compare
Shew_2320 +3.6 17.7 RNA methyltransferase (RefSeq) compare
Shew_1822 +3.6 11.5 aconitate hydratase (RefSeq) compare
Shew_1512 +3.5 12.4 phosphoribosylglycinamide formyltransferase (RefSeq) compare
Shew_2211 +3.4 7.6 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_1230 +3.4 8.9 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_1425 +3.3 14.2 adenylyl-sulfate kinase (RefSeq) compare
Shew_2571 +3.2 21.3 propionyl-CoA carboxylase (RefSeq) compare
Shew_1985 +3.2 10.2 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_1210 +3.2 8.5 stationary-phase survival protein SurE (RefSeq) compare
Shew_1011 +3.1 10.0 citrate transporter (RefSeq) compare
Shew_1302 +3.1 9.0 cytochrome bd ubiquinol oxidase, subunit I (RefSeq) compare
Shew_1601 +3.1 4.1 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1013 +3.1 21.1 aspartate carbamoyltransferase (RefSeq) compare
Shew_1990 +3.1 7.1 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_3413 +3.0 12.0 phosphoribosylamine--glycine ligase (RefSeq) compare
Shew_2502 +3.0 10.3 ABC transporter-related protein (RefSeq) compare
Shew_2584 +3.0 18.5 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_3273 +3.0 14.8 hypothetical protein (RefSeq) compare
Shew_2087 +3.0 7.4 hypothetical protein (RefSeq) compare
Shew_2481 +3.0 16.4 porin (RefSeq) compare
Shew_0086 +3.0 23.0 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_1820 prpB +3.0 3.0 2-methylisocitrate lyase (RefSeq) compare
Shew_1992 +3.0 13.1 hypothetical protein (RefSeq) compare
Shew_2895 +3.0 9.7 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_2302 +2.9 11.1 amidophosphoribosyltransferase (RefSeq) compare
Shew_1050 +2.9 14.7 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_2409 +2.9 6.9 short chain dehydrogenase (RefSeq) compare
Shew_0728 +2.9 16.4 dihydroorotase (RefSeq) compare
Shew_0614 +2.8 8.8 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_1810 +2.8 8.3 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1809 +2.8 18.1 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_3498 rpoZ +2.8 4.4 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_3295 +2.8 19.0 AFG1 family ATPase (RefSeq) compare
Shew_1926 +2.8 6.0 transketolase, central region (RefSeq) compare
Shew_1673 fabG +2.8 4.1 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2573 +2.7 15.5 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_2086 +2.7 3.8 hypothetical protein (RefSeq) compare
Shew_0193 +2.7 6.8 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_1987 +2.6 8.0 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_3710 tdh +2.6 15.1 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1092 +2.6 13.7 amino acid carrier protein (RefSeq) compare
Shew_3499 +2.5 7.4 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_0330 +2.5 1.3 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_0191 +2.5 7.0 cytochrome c, class I (RefSeq) compare
Shew_1925 +2.5 8.8 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_2476 +2.5 4.5 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_3189 +2.4 4.6 hypothetical protein (RefSeq) compare
Shew_2049 +2.4 10.4 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_0613 +2.3 10.8 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_2473 +2.3 4.2 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_1657 sucC +2.3 3.0 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_3709 +2.2 13.8 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_3621 +2.2 1.6 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_1437 +2.2 13.6 transcriptional regulator, TyrR (RefSeq) compare
Shew_1563 +2.2 14.6 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_3716 +2.1 8.2 cytochrome c, class I (RefSeq) compare
Shew_0950 +2.1 6.1 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2837 +2.1 1.5 transcription elongation factor GreA (RefSeq) compare
Shew_3069 +2.1 2.8 5-formyltetrahydrofolate cyclo-ligase (RefSeq) compare
Shew_2839 +2.1 14.2 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_0470 +2.1 3.0 MATE efflux family protein (RefSeq) compare
Shew_2812 deoD +2.0 7.4 purine nucleoside phosphorylase (RefSeq) compare
Shew_2008 +2.0 2.1 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1185 glyA +2.0 6.7 serine hydroxymethyltransferase (RefSeq) compare
Shew_2838 carB +2.0 13.0 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_0942 +2.0 8.8 RDD domain-containing protein (RefSeq) compare
Shew_3568 +1.9 9.0 cation diffusion facilitator family transporter (RefSeq) compare
Shew_3440 +1.9 2.6 prepilin peptidase (RefSeq) compare
Shew_2228 +1.9 10.0 inosine kinase (RefSeq) compare
Shew_0421 +1.9 1.2 phage shock protein C, PspC (RefSeq) compare
Shew_1287 +1.9 3.0 hypothetical protein (RefSeq) compare
Shew_1078 +1.9 10.0 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_2469 +1.8 2.1 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_1555 +1.8 2.2 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_1397 +1.8 3.6 amino acid/peptide transporter (RefSeq) compare
Shew_0763 +1.8 8.0 putative PAS/PAC sensor protein (RefSeq) compare
Shew_1927 +1.7 2.2 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1951 +1.7 5.6 aromatic amino acid aminotransferase (RefSeq) compare
Shew_3681 +1.7 7.3 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2219 +1.6 7.9 hypothetical protein (RefSeq) compare
Shew_1851 +1.6 1.4 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_3718 +1.6 1.5 hypothetical protein (RefSeq) compare
Shew_2919 +1.6 2.9 translation-associated GTPase (RefSeq) compare
Shew_3729 +1.6 1.9 coproporphyrinogen III oxidase (RefSeq) compare
Shew_1145 +1.6 1.5 translation initiation factor Sui1 (RefSeq) compare
Shew_1189 +1.6 8.7 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) compare
Shew_1625 +1.6 2.8 L-serine dehydratase 1 (RefSeq) compare
Shew_0320 +1.6 5.9 frataxin family protein (RefSeq) compare
Shew_0192 +1.5 4.2 TPR repeat-containing protein (RefSeq) compare
Shew_1865 +1.5 6.5 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_3064 gcvT +1.5 8.2 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_1823 +1.5 2.4 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_1839 +1.5 1.7 hypothetical protein (RefSeq) compare
Shew_2906 +1.5 0.9 hypothetical protein (RefSeq) compare
Shew_3682 +1.5 9.7 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_3622 hslO +1.5 8.5 Hsp33-like chaperonin (RefSeq) compare
Shew_1620 +1.5 3.9 adenosylmethionine decarboxylase (RefSeq) compare
Shew_3609 +1.5 2.5 type II secretion system protein N (RefSeq) compare
Shew_1037 +1.4 6.1 DNA mismatch repair protein (RefSeq) compare
Shew_1477 +1.4 2.9 anti-ECFsigma factor, ChrR (RefSeq) compare
Shew_1213 +1.4 1.7 RpoD family RNA polymerase sigma factor (RefSeq) compare
Shew_3062 +1.4 7.8 glycine dehydrogenase (RefSeq) compare
Shew_1559 +1.4 0.9 hypothetical protein (RefSeq) compare
Shew_3432 pdhR +1.4 3.0 transcriptional regulator PdhR (RefSeq) compare
Shew_1867 +1.4 4.0 hypothetical protein (RefSeq) compare
Shew_3759 +1.4 8.2 imidazolonepropionase (RefSeq) compare
Shew_0127 +1.3 3.1 LexA repressor (RefSeq) compare
Shew_2907 +1.3 1.4 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_3065 +1.3 7.9 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_1602 +1.3 2.2 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_0430 +1.3 2.6 histone family protein DNA-binding protein (RefSeq) compare
Shew_3548 +1.3 1.4 hypothetical protein (RefSeq) compare
Shew_3063 +1.3 1.3 glycine cleavage system protein H (RefSeq) compare
Shew_0326 +1.3 3.8 HAD family hydrolase (RefSeq) compare
Shew_3150 +1.3 1.4 antibiotic biosynthesis monooxygenase (RefSeq) compare
Shew_2570 +1.3 10.4 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_2813 +1.3 1.7 phosphopentomutase (RefSeq) compare
Shew_1574 +1.3 2.9 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_3255 +1.3 1.2 hypothetical protein (RefSeq) compare
Shew_1481 +1.3 1.4 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_2410 +1.3 0.6 beta-ketoacyl synthase (RefSeq) compare
Shew_2285 +1.3 1.2 UDP-glucose 4-epimerase (RefSeq) compare
Shew_1209 +1.2 2.7 pseudouridylate synthase (RefSeq) compare
Shew_1667 +1.2 3.2 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_3395 +1.2 1.5 radical SAM domain-containing protein (RefSeq) compare
Shew_1920 +1.2 3.1 alpha/beta hydrolase fold (RefSeq) compare
Shew_0585 +1.2 3.3 cAMP-regulatory protein (RefSeq) compare
Shew_3054 +1.2 0.9 hypothetical protein (RefSeq) compare
Shew_3099 +1.2 1.2 TetR family transcriptional regulator (RefSeq) compare
Shew_0462 +1.2 0.8 hypothetical protein (RefSeq) compare
Shew_0469 +1.2 0.7 pentapeptide repeat-containing protein (RefSeq) compare
Shew_1214 +1.2 6.5 DNA mismatch repair protein (RefSeq) compare
Shew_3500 +1.2 2.1 putative endoribonuclease L-PSP (RefSeq) compare
Shew_2435 +1.2 5.2 sodium/proline symporter (RefSeq) compare
Shew_2013 +1.2 1.6 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_2061 +1.2 2.2 radical SAM domain-containing protein (RefSeq) compare
Shew_2414 +1.2 0.8 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_0594 +1.2 3.2 hypothetical protein (RefSeq) compare
Shew_3197 +1.1 1.0 hypothetical protein (RefSeq) compare
Shew_1188 +1.1 3.0 riboflavin synthase subunit alpha (RefSeq) compare
Shew_3271 +1.1 5.8 galactokinase (RefSeq) compare
Shew_2252 +1.1 0.9 anthranilate synthase component II (RefSeq) compare
Shew_3431 aceE +1.1 7.8 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_1439 +1.1 4.2 maleylacetoacetate isomerase (RefSeq) compare
Shew_0372 +1.1 1.6 hypothetical protein (RefSeq) compare
Shew_2264 +1.1 1.7 hypothetical protein (RefSeq) compare
Shew_3261 +1.1 1.0 thiopurine S-methyltransferase (RefSeq) compare
Shew_1796 +1.1 2.6 hypothetical protein (RefSeq) compare
Shew_0579 +1.1 5.1 arginine N-succinyltransferase (RefSeq) compare
Shew_0767 +1.1 3.0 ATP-dependent RNA helicase SrmB (RefSeq) compare
Shew_2558 +1.1 1.4 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_2213 +1.1 2.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (RefSeq) compare
Shew_1473 +1.0 4.1 hypothetical protein (RefSeq) compare
Shew_3292 +1.0 1.5 hypothetical protein (RefSeq) compare
Shew_2646 +1.0 0.9 hypothetical protein (RefSeq) compare
Shew_1978 +1.0 0.9 hypothetical protein (RefSeq) compare
Shew_3404 +1.0 0.8 NosL family protein (RefSeq) compare
Shew_0322 +1.0 4.2 diaminopimelate decarboxylase (RefSeq) compare
Shew_0615 +1.0 4.0 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_0441 +1.0 3.1 dehydratase (RefSeq) compare
Shew_3361 +1.0 1.9 hypothetical protein (RefSeq) compare
Shew_0268 +1.0 1.0 transcriptional antiterminator, Rof (RefSeq) compare
Shew_3035 +1.0 1.4 hypothetical protein (RefSeq) compare
Shew_3055 +1.0 1.6 CMP/dCMP deaminase, zinc-binding (RefSeq) compare
Shew_0628 +1.0 7.1 (glutamate--ammonia-ligase) adenylyltransferase (RefSeq) compare
Shew_0359 fre +1.0 4.0 FMN reductase (RefSeq) compare
Shew_2819 +1.0 1.5 hypothetical protein (RefSeq) compare
Shew_2241 +1.0 1.1 hypothetical protein (RefSeq) compare
Shew_1173 +1.0 2.1 hypothetical protein (RefSeq) compare
Shew_0453 +0.9 1.2 response regulator receiver protein (RefSeq) compare
Shew_0022 +0.9 6.8 TrkH family potassium uptake protein (RefSeq) compare
Shew_0619 +0.9 5.0 adenylate cyclase (RefSeq) compare


Specific Phenotypes

For 3 genes in this experiment

For stress 1-ethyl-3-methylimidazolium lysine in Shewanella loihica PV-4

For stress 1-ethyl-3-methylimidazolium lysine across organisms