Experiment set4IT010 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Polymyxin B sulfate 0.05 mg/ml

200 most important genes:

  gene name fitness t score description  
Ga0059261_0171 -3.8 -3.6 Thiol-disulfide isomerase and thioredoxins compare
Ga0059261_0790 -3.8 -4.4 putative membrane protein insertion efficiency factor compare
Ga0059261_0170 -3.5 -6.7 Uncharacterized protein involved in biosynthesis of c-type cytochromes compare
Ga0059261_3615 -3.5 -2.7 hypothetical protein compare
Ga0059261_4188 -3.3 -8.2 pyridoxal-dependent decarboxylase, exosortase A system-associated compare
Ga0059261_1370 -3.2 -9.9 Signal transduction histidine kinase compare
Ga0059261_4187 -3.2 -12.9 acyl-CoA ligase (AMP-forming), exosortase A-associated compare
Ga0059261_2189 -3.1 -9.5 uncharacterized domain 1 compare
Ga0059261_1382 -3.1 -9.0 periplasmic serine protease, Do/DeqQ family compare
Ga0059261_2707 -3.0 -7.7 fructose-1,6-bisphosphatase, class II compare
Ga0059261_1369 -3.0 -12.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_3637 -2.9 -4.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_3191 -2.9 -9.5 Glycosyltransferases involved in cell wall biogenesis compare
Ga0059261_4186 -2.7 -2.4 Phosphopantetheine attachment site compare
Ga0059261_2021 -2.7 -15.6 Protein of unknown function (DUF2029) compare
Ga0059261_0172 -2.6 -10.0 Cytochrome c biogenesis factor compare
Ga0059261_0175 -2.5 -9.0 heme exporter protein CcmC compare
Ga0059261_2213 -2.4 -8.0 Domain of unknown function (DUF3576) compare
Ga0059261_0349 -2.4 -5.6 MarR family compare
Ga0059261_1360 -2.3 -11.4 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Ga0059261_0163 -2.3 -4.8 Major Facilitator Superfamily compare
Ga0059261_1560 -2.2 -4.5 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Ga0059261_3255 -2.1 -8.1 hypothetical protein compare
Ga0059261_0613 -2.1 -4.7 FecR family protein compare
Ga0059261_2314 -2.0 -5.5 Protein-disulfide isomerase compare
Ga0059261_2190 -2.0 -5.0 PTS IIA-like nitrogen-regulatory protein PtsN compare
Ga0059261_2181 -2.0 -13.5 penicillin-binding protein, 1A family compare
Ga0059261_2417 -1.9 -4.7 phytoene desaturase compare
Ga0059261_0741 -1.9 -13.7 Domain of unknown function (DUF4403) compare
Ga0059261_2490 -1.9 -6.3 Small protein A (tmRNA-binding) compare
Ga0059261_2444 -1.9 -6.8 5-aminolevulinic acid synthase compare
Ga0059261_3671 -1.8 -3.5 Citrate lyase beta subunit compare
Ga0059261_3190 -1.8 -12.1 3-isopropylmalate dehydrogenase compare
Ga0059261_1507 -1.8 -3.2 deoxycytidine triphosphate deaminase compare
Ga0059261_3748 -1.8 -3.4 ribosomal protein L15, bacterial/organelle compare
Ga0059261_2179 -1.7 -9.4 Phospholipid N-methyltransferase compare
Ga0059261_3339 -1.6 -7.6 ATP-dependent protease HslVU, ATPase subunit compare
Ga0059261_3159 -1.6 -5.0 TolR protein compare
Ga0059261_3101 -1.6 -4.1 nucleotide sugar dehydrogenase compare
Ga0059261_1563 -1.6 -2.2 cytochrome bo3 quinol oxidase subunit 4 (EC 1.10.3.-) compare
Ga0059261_1909 -1.5 -7.0 MAF protein compare
Ga0059261_1444 -1.5 -11.5 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Ga0059261_3879 -1.4 -5.3 outer membrane autotransporter barrel domain compare
Ga0059261_2498 -1.4 -4.8 hypothetical protein compare
Ga0059261_3160 -1.4 -4.5 TolQ protein compare
Ga0059261_2034 -1.4 -9.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_3488 -1.4 -2.5 Histidine kinase/HAMP domain compare
Ga0059261_3156 -1.4 -5.4 peptidoglycan-associated lipoprotein compare
Ga0059261_3341 -1.3 -5.8 ATP-dependent protease HslVU, peptidase subunit compare
Ga0059261_1911 -1.3 -2.2 Thioredoxin-like proteins and domains compare
Ga0059261_2980 -1.3 -11.1 Outer membrane protein compare
Ga0059261_0174 -1.3 -1.5 hypothetical protein compare
Ga0059261_1293 -1.3 -9.4 (p)ppGpp synthetase, RelA/SpoT family compare
Ga0059261_2005 -1.3 -4.1 protoheme IX farnesyltransferase compare
Ga0059261_3130 -1.3 -7.1 Lipid A core - O-antigen ligase and related enzymes compare
Ga0059261_2981 -1.3 -10.4 Uncharacterized protein conserved in bacteria compare
Ga0059261_0245 -1.2 -2.2 pseudouridine synthase compare
Ga0059261_3196 -1.2 -2.2 Transcriptional regulator compare
Ga0059261_3119 -1.2 -3.7 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_3097 -1.2 -5.2 Calcineurin-like phosphoesterase compare
Ga0059261_3127 -1.2 -5.8 hypothetical protein compare
Ga0059261_3502 -1.2 -2.8 Fatty acid desaturase compare
Ga0059261_3114 -1.2 -6.8 hypothetical protein compare
Ga0059261_1035 -1.2 -2.7 hypothetical protein compare
Ga0059261_4025 -1.2 -2.8 Nucleotidyl transferase compare
Ga0059261_1368 -1.1 -2.6 hypothetical protein compare
Ga0059261_0321 -1.1 -1.9 hypothetical protein compare
Ga0059261_1001 -1.0 -6.7 ATP-dependent Clp protease ATP-binding subunit ClpA (EC 3.4.21.92) compare
Ga0059261_3157 -1.0 -7.9 tol-pal system beta propeller repeat protein TolB compare
Ga0059261_0875 -1.0 -2.4 Leucyl aminopeptidase compare
Ga0059261_3876 -1.0 -6.6 Signal transduction histidine kinase compare
Ga0059261_0638 -1.0 -7.9 type I secretion outer membrane protein, TolC family compare
Ga0059261_1312 -1.0 -3.9 amino acid/peptide transporter (Peptide:H+ symporter), bacterial compare
Ga0059261_1600 -1.0 -2.8 Domain of unknown function (DUF4167) compare
Ga0059261_2191 -1.0 -4.6 ribosomal subunit interface protein compare
Ga0059261_1846 -0.9 -5.6 Xaa-Pro aminopeptidase compare
Ga0059261_0664 -0.9 -1.7 pseudouridine synthase, RluA family compare
Ga0059261_1605 -0.9 -5.0 transcriptional regulator, TetR family compare
Ga0059261_0918 -0.9 -4.1 Phosphotransferase system, mannose/fructose-specific component IIA compare
Ga0059261_3878 -0.9 -6.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_2145 -0.9 -3.9 ribosome-binding factor A compare
Ga0059261_2013 -0.9 -6.7 signal peptidase I, bacterial type compare
Ga0059261_3874 -0.9 -4.8 ABC-type antimicrobial peptide transport system, ATPase component compare
Ga0059261_0121 -0.9 -2.1 Sporulation related domain compare
Ga0059261_3340 -0.8 -4.6 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) compare
Ga0059261_4209 -0.8 -7.0 Transglycosylase SLT domain compare
Ga0059261_2514 -0.8 -6.2 phosphoenolpyruvate-protein phosphotransferase compare
Ga0059261_1285 -0.8 -4.8 Uncharacterized conserved protein compare
Ga0059261_1565 -0.8 -6.3 cytochrome bo3 quinol oxidase subunit 1 apoprotein (EC 1.10.3.-) compare
Ga0059261_0369 -0.8 -1.6 ribosomal protein L9 compare
Ga0059261_4046 -0.8 -2.2 Response regulator receiver domain compare
Ga0059261_3211 -0.8 -4.9 hypothetical protein compare
Ga0059261_0069 -0.8 -3.7 tRNA dimethylallyltransferase compare
Ga0059261_0991 -0.8 -5.4 Methionine synthase I (cobalamin-dependent), methyltransferase domain compare
Ga0059261_0622 -0.8 -4.5 ABC-type Fe3+-hydroxamate transport system, periplasmic component compare
Ga0059261_0037 -0.8 -5.2 hypothetical protein compare
Ga0059261_0990 -0.7 -6.4 methionine synthase (B12-dependent) (EC 2.1.1.13) compare
Ga0059261_3276 -0.7 -4.5 ABC-type multidrug transport system, ATPase and permease components compare
Ga0059261_2285 -0.7 -1.1 Fe2+ transport system protein A compare
Ga0059261_3657 -0.7 -4.3 His Kinase A (phospho-acceptor) domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_0464 -0.7 -1.5 hypothetical protein compare
Ga0059261_0181 -0.7 -4.1 Predicted membrane-associated Zn-dependent proteases 1 compare
Ga0059261_3796 -0.7 -4.7 Predicted transcriptional regulator compare
Ga0059261_1075 -0.7 -1.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_0304 -0.7 -1.4 Bacterioferritin-associated ferredoxin compare
Ga0059261_2286 -0.7 -3.4 Fe2+ transport system protein B compare
Ga0059261_1335 -0.7 -2.5 Predicted ATPase compare
Ga0059261_0136 -0.7 -2.9 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation compare
Ga0059261_1696 -0.7 -2.4 Pyridine nucleotide-disulphide oxidoreductase/Reductase C-terminal compare
Ga0059261_1301 -0.7 -2.5 Methyltransferase domain compare
Ga0059261_3103 -0.7 -2.2 Glycosyltransferase compare
Ga0059261_3153 -0.7 -2.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_1985 -0.7 -1.7 transcriptional regulator NrdR compare
Ga0059261_0089 -0.7 -3.3 trigger factor compare
Ga0059261_2458 -0.7 -4.1 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases compare
Ga0059261_1545 -0.7 -2.7 Fe2+/Zn2+ uptake regulation proteins compare
Ga0059261_0290 -0.7 -3.0 3-dehydroquinate dehydratase (EC 4.2.1.10) compare
Ga0059261_1877 -0.7 -5.9 Cation/multidrug efflux pump compare
Ga0059261_0204 -0.7 -2.7 protein RecA compare
Ga0059261_0623 -0.7 -2.7 ABC-type Fe3+-siderophore transport system, permease component compare
Ga0059261_0650 -0.6 -1.3 Negative regulator of beta-lactamase expression compare
Ga0059261_1561 -0.6 -3.3 Signal transduction histidine kinase compare
Ga0059261_0889 -0.6 -1.7 Cold shock proteins compare
Ga0059261_3979 -0.6 -2.2 elongation factor 4 compare
Ga0059261_1724 -0.6 -2.0 hypothetical protein compare
Ga0059261_0493 -0.6 -1.4 hypothetical protein compare
Ga0059261_0494 -0.6 -1.6 ABC-type antimicrobial peptide transport system, ATPase component compare
Ga0059261_0620 -0.6 -5.4 Outer membrane cobalamin receptor protein compare
Ga0059261_3956 -0.6 -3.9 amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-) compare
Ga0059261_3430 -0.6 -1.9 NADH:ubiquinone oxidoreductase 17.2 kD subunit compare
Ga0059261_0146 -0.6 -1.2 amidohydrolase, PncC family compare
Ga0059261_1564 -0.6 -2.3 cytochrome bo3 quinol oxidase subunit 3 (EC 1.10.3.-) compare
Ga0059261_2418 -0.6 -2.3 lycopene cyclase compare
Ga0059261_1562 -0.6 -2.8 Uncharacterized conserved protein compare
Ga0059261_3497 -0.6 -4.0 Membrane proteins related to metalloendopeptidases compare
Ga0059261_2547 -0.6 -0.9 tRNA compare
Ga0059261_2951 -0.6 -1.8 Heavy-metal resistance compare
Ga0059261_4139 -0.6 -1.3 hypothetical protein compare
Ga0059261_1566 -0.6 -3.6 cytochrome o ubiquinol oxidase subunit II compare
Ga0059261_3955 -0.6 -3.8 hypothetical protein compare
Ga0059261_0719 -0.6 -2.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_1258 -0.6 -5.3 TonB-dependent siderophore receptor compare
Ga0059261_3759 -0.6 -0.9 hypothetical protein compare
Ga0059261_3128 -0.6 -4.5 capsular exopolysaccharide family compare
Ga0059261_2743 -0.6 -2.5 hypothetical protein compare
Ga0059261_1026 -0.6 -1.8 DNA repair protein RecN compare
Ga0059261_0153 -0.6 -1.8 Serine acetyltransferase compare
Ga0059261_1257 -0.6 -3.3 Uncharacterized iron-regulated protein compare
Ga0059261_2948 -0.6 -2.2 Putative copper export protein compare
Ga0059261_0350 -0.5 -3.2 Bacterial SH3 domain compare
Ga0059261_2214 -0.5 -3.5 hypothetical protein compare
Ga0059261_1451 -0.5 -2.2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) compare
Ga0059261_3945 -0.5 -3.9 type II secretion system protein D compare
Ga0059261_2501 -0.5 -3.4 C-terminal peptidase (prc) compare
Ga0059261_4204 -0.5 -2.0 transcriptional regulator, TetR family compare
Ga0059261_3866 -0.5 -3.8 cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein (EC 1.10.3.10) compare
Ga0059261_1287 -0.5 -3.5 poly(R)-hydroxyalkanoic acid synthase, class I compare
Ga0059261_1986 -0.5 -2.6 Glycine/serine hydroxymethyltransferase compare
Ga0059261_0276 -0.5 -1.9 Protein required for attachment to host cells compare
Ga0059261_4169 -0.5 -1.6 Kef-type K+ transport system, predicted NAD-binding component compare
Ga0059261_2266 -0.5 -2.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_0846 -0.5 -2.7 Zn-dependent alcohol dehydrogenases, class III compare
Ga0059261_3125 -0.5 -0.9 Imidazoleglycerol-phosphate synthase compare
Ga0059261_3347 -0.5 -1.8 Domain of unknown function DUF87 compare
Ga0059261_1919 -0.5 -3.9 L,D-transpeptidase catalytic domain compare
Ga0059261_1115 -0.5 -1.1 Chemotaxis protein; stimulates methylation of MCP proteins compare
Ga0059261_1449 -0.5 -2.7 Glycine zipper 2TM domain compare
Ga0059261_0624 -0.5 -2.9 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components compare
Ga0059261_2892 -0.5 -1.8 hypothetical protein compare
Ga0059261_4145 -0.5 -2.8 phage shock protein C (PspC) family protein compare
Ga0059261_0131 -0.5 -2.4 hypothetical protein compare
Ga0059261_2326 -0.5 -2.0 Phosphohistidine phosphatase SixA compare
Ga0059261_1190 -0.5 -2.4 hypothetical protein compare
Ga0059261_3569 -0.5 -1.3 chaperone protein DnaJ compare
Ga0059261_1912 -0.5 -1.4 Nitroreductase compare
Ga0059261_1095 -0.5 -2.8 Flagellar motor switch protein compare
Ga0059261_0449 -0.5 -2.0 Uncharacterized protein, homolog of Cu resistance protein CopC compare
Ga0059261_3207 -0.5 -2.1 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_2243 -0.5 -1.1 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_1017 -0.5 -2.5 tRNA-guanine transglycosylase compare
Ga0059261_3481 -0.5 -2.6 Beta-glucosidase-related glycosidases compare
Ga0059261_3490 -0.4 -3.1 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_0214 -0.4 -3.9 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Ga0059261_2684 -0.4 -0.9 hypothetical protein compare
Ga0059261_2293 -0.4 -2.5 cell division ATP-binding protein FtsE compare
Ga0059261_0852 -0.4 -2.6 Transcriptional regulators compare
Ga0059261_3512 -0.4 -1.0 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
Ga0059261_1573 -0.4 -2.1 hypothetical protein compare
Ga0059261_3129 -0.4 -2.9 SLBB domain/Polysaccharide biosynthesis/export protein compare
Ga0059261_0255 -0.4 -1.3 SurA N-terminal domain/PPIC-type PPIASE domain compare
Ga0059261_1872 -0.4 -1.9 HAD-superfamily subfamily IB hydrolase, TIGR01490 compare
Ga0059261_2422 -0.4 -2.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_2737 -0.4 -2.6 UTP--GlnB (protein PII) uridylyltransferase, GlnD compare
Ga0059261_1057 -0.4 -1.9 hypothetical protein compare
Ga0059261_2481 -0.4 -2.1 Ppx/GppA phosphatase family compare
Ga0059261_1138 -0.4 -1.4 hypothetical protein compare
Ga0059261_3545 -0.4 -1.0 hypothetical protein compare
Ga0059261_4001 -0.4 -2.1 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Ga0059261_2560 -0.4 -3.0 transcriptional regulator, TetR family compare
Ga0059261_1998 -0.4 -2.8 Predicted SAM-dependent methyltransferases compare


Specific Phenotypes

For 2 genes in this experiment

For stress Polymyxin B sulfate in Sphingomonas koreensis DSMZ 15582

For stress Polymyxin B sulfate across organisms