Experiment set4IT008 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

BHIS with Lomefloxacin hydrochloride 0.025 mM

200 most detrimental genes:

  gene name fitness t score description  
BT4575 +2.6 6.4 hypothetical protein (NCBI ptt file) compare
BT0173 +2.5 9.2 conserved hypothetical protein (NCBI ptt file) compare
BT4576 +2.1 4.3 hypothetical protein (NCBI ptt file) compare
BT1739 +2.0 13.7 excinuclease ABC subunit A (NCBI ptt file) compare
BT0570 +2.0 10.9 excinuclease ABC subunit B (NCBI ptt file) compare
BT0578 +1.7 8.9 excinuclease ABC subunit A (NCBI ptt file) compare
BT2836 +1.3 9.5 2-oxoglutarate synthase subunit korA (NCBI ptt file) compare
BT2006 +1.3 2.6 hypothetical protein (NCBI ptt file) compare
BT0013 +1.3 2.1 hypothetical protein (NCBI ptt file) compare
BT2837 +1.3 8.0 2-oxoglutarate synthase subunit korB (NCBI ptt file) compare
BT1976 +1.2 3.8 hypothetical protein (NCBI ptt file) compare
BT4453 +1.2 2.4 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT0783 +1.2 1.5 hypothetical protein (NCBI ptt file) compare
BT4574 +1.2 0.5 conserved hypothetical protein (NCBI ptt file) compare
BT1186 +1.1 1.9 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT3211 +1.1 2.9 conserved hypothetical protein (NCBI ptt file) compare
BT0900 +1.1 3.6 putative tetratricopeptide repeat family protein (NCBI ptt file) compare
BT4002 +1.1 1.9 ATPase, ParA family (NCBI ptt file) compare
BT0098 +1.0 1.4 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT2302 +1.0 1.3 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT3368 +1.0 2.3 putative glycosyltransferase (NCBI ptt file) compare
BT3022 +1.0 3.1 hypothetical protein (NCBI ptt file) compare
BT1211 +1.0 2.4 hypothetical protein (NCBI ptt file) compare
BT0007 +1.0 2.5 hypothetical protein (NCBI ptt file) compare
BT3915 +1.0 1.9 hypothetical protein (NCBI ptt file) compare
BT3414 +1.0 5.5 Mg2+/Co2+ transporter (NCBI ptt file) compare
BT2299 +1.0 2.7 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1263 +1.0 1.9 putative protease I (NCBI ptt file) compare
BT1679 +0.9 2.0 hypothetical protein (NCBI ptt file) compare
BT1680 +0.9 2.5 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT0004 +0.9 1.5 hypothetical protein (NCBI ptt file) compare
BT0427 +0.9 2.6 xanthine phosphoribosyltransferase (NCBI ptt file) compare
BT0437 +0.9 1.5 N-acylglucosamine 2-epimerase (NCBI ptt file) compare
BT2003 +0.9 2.4 putative membrane peptidase (NCBI ptt file) compare
BT4062 +0.9 4.1 NADH dehydrogenase I, chain J (NCBI ptt file) compare
BT3253 +0.9 3.3 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT1202 +0.8 1.5 UDP-N-acetylglucosamine 2-epimerase (NCBI ptt file) compare
BT0215 +0.8 2.3 iron uptake regulatory protein (NCBI ptt file) compare
BT3303 +0.8 4.6 ATP-dependent RNA helicase (NCBI ptt file) compare
BT4678 +0.8 4.6 L-serine dehydratase (NCBI ptt file) compare
BT4333 +0.8 3.9 hypothetical protein (NCBI ptt file) compare
BT0068 +0.8 1.4 hypothetical protein (NCBI ptt file) compare
BT2236 +0.8 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT4211 +0.8 3.0 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
BT0611 +0.8 2.5 glycosyltransferase (NCBI ptt file) compare
BT4195 +0.8 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT3981 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT0061 +0.8 2.8 putative tyrosine-protein kinase ptk (NCBI ptt file) compare
BT0443 +0.8 1.7 thermostable beta-glucosidase B (NCBI ptt file) compare
BT4529 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT0912 +0.8 2.3 DNA-binding protein HU (NCBI ptt file) compare
BT3268 +0.8 2.5 glucose-inhibited division protein A (NCBI ptt file) compare
BT3195 +0.8 4.2 conserved hypothetical protein (NCBI ptt file) compare
BT1169 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT1713 +0.8 2.7 putative acylneuraminate cytidylyltransferase (NCBI ptt file) compare
BT1215 +0.8 2.4 ABC transporter, permease protein (NCBI ptt file) compare
BT0651 +0.8 1.6 thiamine biosynthesis protein ThiG (NCBI ptt file) compare
BT4042 +0.8 4.4 putative Mg2+ transporter MgtE (NCBI ptt file) compare
BT2749 +0.7 5.7 putative membrane-associated HD superfamily hydrolase (NCBI ptt file) compare
BT2122 +0.7 1.9 lysyl-tRNA synthetase (NCBI ptt file) compare
BT2417 +0.7 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT0652 +0.7 1.1 putative thiamine-phosphate pyrophosphorylase (NCBI ptt file) compare
BT1385 +0.7 2.8 transcriptional regulator (NCBI ptt file) compare
BT2994 +0.7 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT1541 +0.7 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT4699 +0.7 2.2 putative hydrolase, haloacid dehalogenase-like hydrolase (NCBI ptt file) compare
BT0658 +0.7 2.4 hypothetical protein (NCBI ptt file) compare
BT0227 +0.7 2.3 hypothetical protein (NCBI ptt file) compare
BT0242 +0.7 2.0 putative polysaccharide deacetylase (NCBI ptt file) compare
BT1127 +0.7 1.2 mobilization protein BmgB (NCBI ptt file) compare
BT4524 +0.7 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT1072 +0.7 1.4 hypothetical protein (NCBI ptt file) compare
BT1201 +0.7 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT4677 +0.7 2.5 hypothetical protein (NCBI ptt file) compare
BT3200 +0.7 1.2 putative N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT3318 +0.7 3.3 signal peptidase I (NCBI ptt file) compare
BT3165 +0.7 3.3 tRNA/rRNA methyltransferase (NCBI ptt file) compare
BT4193 +0.7 4.6 dipeptidyl peptidase IV (NCBI ptt file) compare
BT2010 +0.7 1.2 hypothetical protein (NCBI ptt file) compare
BT1580 +0.7 1.6 lactoylglutathione lyase (NCBI ptt file) compare
BT1108 +0.6 2.2 conserved hypothetical protein, putative integral membrane protein (NCBI ptt file) compare
BT4527 +0.6 1.9 hypothetical protein (NCBI ptt file) compare
BT2844 +0.6 4.4 conserved hypothetical protein (NCBI ptt file) compare
BT2616 +0.6 3.2 hypothetical protein (NCBI ptt file) compare
BT2280 +0.6 1.2 hypothetical protein (NCBI ptt file) compare
BT1920 +0.6 3.0 hypothetical protein (NCBI ptt file) compare
BT1141 +0.6 2.5 cation efflux family protein (NCBI ptt file) compare
BT0531 +0.6 1.4 anthranilate synthase component II (NCBI ptt file) compare
BT0199 +0.6 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT1519 +0.6 2.2 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT3803 +0.6 2.3 putative zinc protease (NCBI ptt file) compare
BT4361 +0.6 2.5 hypothetical protein (NCBI ptt file) compare
BT4300 +0.6 2.2 transcription regulator, CRP family (NCBI ptt file) compare
BT1733 +0.6 4.1 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT2993 +0.6 1.7 hypothetical protein (NCBI ptt file) compare
BT1529 +0.6 2.5 two-component system response regulator (NCBI ptt file) compare
BT0405 +0.6 0.7 hypothetical protein (NCBI ptt file) compare
BT2161 +0.6 1.7 50S ribosomal protein L9 (NCBI ptt file) compare
BT1149 +0.6 3.1 Type II restriction enzyme HpaII (NCBI ptt file) compare
BT3042 +0.6 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0216 +0.6 1.3 putative rubrerythrin (NCBI ptt file) compare
BT1065 +0.6 1.8 hypothetical protein (NCBI ptt file) compare
BT4332 +0.6 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT4768 +0.6 1.3 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0337 +0.6 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1513 +0.6 2.5 integrase (NCBI ptt file) compare
BT4065 +0.6 4.1 NADH dehydrogenase I, chain D (NCBI ptt file) compare
BT1287 +0.6 2.0 hypothetical protein (NCBI ptt file) compare
BT0211 +0.6 2.8 hypothetical protein (NCBI ptt file) compare
BT0079 +0.6 2.2 putative anti-restriction protein (NCBI ptt file) compare
BT4666 +0.6 1.5 putative K+ uptake system protein (NCBI ptt file) compare
BT1684 +0.6 2.8 conserved hypothetical protein (NCBI ptt file) compare
BT1667 +0.6 1.5 hypothetical protein (NCBI ptt file) compare
BT3729 +0.6 2.5 putative protoporphyrinogen oxidase (NCBI ptt file) compare
BT4046 +0.6 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT4531 +0.6 2.4 conserved hypothetical protein (NCBI ptt file) compare
BT0291 +0.6 2.6 integrase (NCBI ptt file) compare
BT4534 +0.6 2.0 hypothetical protein (NCBI ptt file) compare
BT4513 +0.6 1.8 putative rRNA methylase (NCBI ptt file) compare
BT1132 +0.6 1.5 hypothetical protein (NCBI ptt file) compare
BT2446 +0.6 1.8 integrase (NCBI ptt file) compare
BT2652 +0.6 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT1576 +0.6 0.9 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT2206 +0.6 1.6 Zinc ABC transporter, permease (NCBI ptt file) compare
BT0400 +0.5 1.4 putative tyrosine-protein kinase in capsular polysaccharide biosynthesis region (NCBI ptt file) compare
BT_t17 pseudo-tRNA +0.5 1.6 tRNA-OTHER (RefSeq) compare
BT2303 +0.5 1.7 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1518 +0.5 1.7 hypothetical protein (NCBI ptt file) compare
BT1451 +0.5 1.7 hypothetical protein (NCBI ptt file) compare
BT2043 +0.5 1.9 hypothetical protein (NCBI ptt file) compare
BT0848 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT3509 +0.5 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT3064 +0.5 2.7 hypothetical protein (NCBI ptt file) compare
BT1922 +0.5 2.6 putative N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT4331 +0.5 3.8 conserved hypothetical protein (NCBI ptt file) compare
BT2180 +0.5 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT3405 +0.5 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1994 +0.5 1.3 hypothetical protein (NCBI ptt file) compare
BT0200 +0.5 2.0 ATP phosphoribosyltransferase (NCBI ptt file) compare
BT0519 +0.5 1.9 hypothetical protein (NCBI ptt file) compare
BT2153 +0.5 1.1 putative Fe-S oxidoreductases (NCBI ptt file) compare
BT4442 +0.5 1.1 hypothetical protein (NCBI ptt file) compare
BT2750 +0.5 2.6 putative protein-tyrosine-phosphatase (NCBI ptt file) compare
BT4477 +0.5 1.4 putative ATP-dependent DNA helicase (NCBI ptt file) compare
BT0814 +0.5 1.8 conserved hypothetical protein, putative outer membrane protein (NCBI ptt file) compare
BT0786 +0.5 2.1 putative integral membrane protein (NCBI ptt file) compare
BT0542 +0.5 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT4777 +0.5 1.3 hypothetical protein (NCBI ptt file) compare
BT0747 +0.5 2.1 putative phosphatidylinositol-4-phosphate 5-kinase (NCBI ptt file) compare
BT3397 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT1811 +0.5 1.6 hypothetical protein (NCBI ptt file) compare
BT3343 +0.5 2.1 putative phenylacetic acid degradation protein (NCBI ptt file) compare
BT0702 +0.5 1.5 chloramphenicol acetyltransferase (CAT-III) (NCBI ptt file) compare
BT0751 +0.5 1.5 putative efflux pump component protein (NCBI ptt file) compare
BT3317 +0.5 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT0699 +0.5 2.0 putative sugar transporter (NCBI ptt file) compare
BT1200 +0.5 1.3 hypothetical protein (NCBI ptt file) compare
BT1480 +0.5 2.8 hypothetical protein (NCBI ptt file) compare
BT0723 +0.5 0.8 hypothetical protein (NCBI ptt file) compare
BT4757 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT0035 +0.5 1.0 hypothetical protein (NCBI ptt file) compare
BT0230 +0.5 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1784 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT2297 +0.5 1.8 putative reverse transcriptase (NCBI ptt file) compare
BT0591 +0.5 1.9 hypothetical protein (NCBI ptt file) compare
BT2208 +0.5 2.0 hypothetical protein (NCBI ptt file) compare
BT4043 +0.5 2.5 dimethyladenosine transferase (NCBI ptt file) compare
p5482_21 +0.5 2.6 hypothetical protein (NCBI) compare
BT4036 +0.5 0.8 hypothetical protein (NCBI ptt file) compare
BT0952 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT1493 +0.5 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT2640 +0.5 2.2 hypothetical protein (NCBI ptt file) compare
BT1399 +0.5 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1214 +0.5 1.4 putative ABC transporter ATP-binding protein (NCBI ptt file) compare
BT3869 +0.5 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT4755 +0.5 2.4 putative two-component system sensor histidine kinase, putative heat shock protein (NCBI ptt file) compare
BT0006 +0.5 1.4 hypothetical protein (NCBI ptt file) compare
BT1585 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT1564 +0.5 1.2 conserved hypothetical protein (NCBI ptt file) compare
BT0254 +0.5 2.3 putative Fe-S oxidoreductase (NCBI ptt file) compare
BT3075 +0.5 3.1 NAD-dependent epimerase/dehydratase family protein (NCBI ptt file) compare
BT4532 +0.5 1.8 hypothetical protein (NCBI ptt file) compare
BT3617 +0.5 1.4 sorbitol dehydrogenase (NCBI ptt file) compare
BT0804 +0.5 1.9 putative carbon-nitrogen hydrolase (NCBI ptt file) compare
BT2515 +0.5 1.8 hypothetical protein (NCBI ptt file) compare
BT4469 +0.5 1.3 conserved hypothetical protein (NCBI ptt file) compare
BT2781 +0.5 1.2 putative mannose-1-phosphate guanylyltransferase (NCBI ptt file) compare
BT1388 +0.5 1.8 integral membrane protein (NCBI ptt file) compare
BT3037 +0.5 2.0 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2436 +0.5 3.1 putative secreted tripeptidyl aminopeptidase (NCBI ptt file) compare
BT0107 +0.5 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT1320 +0.5 1.6 putative transcriptional regulator, phosphate uptake regulation (NCBI ptt file) compare
BT0674 +0.5 1.6 carboxynorspermidine decarboxylase (NCBI ptt file) compare
BT4452 +0.5 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT4034 +0.5 1.1 hypothetical protein (NCBI ptt file) compare
BT0665 +0.4 1.7 hypothetical protein (NCBI ptt file) compare
BT0100 +0.4 1.2 hypothetical protein (NCBI ptt file) compare
BT4455 +0.4 1.8 oxidoreductase, putative glycolate oxidase (NCBI ptt file) compare
BT0271 +0.4 1.6 hypothetical protein (NCBI ptt file) compare
BT3502 +0.4 1.0 hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 7 genes in this experiment

For stress Lomefloxacin hydrochloride in Bacteroides thetaiotaomicron VPI-5482

For stress Lomefloxacin hydrochloride across organisms