Experiment set4IT003 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS03315		-3.0	-1.7	ferrous iron transport protein A
MMP_RS06285		-2.8	-3.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS07005		-2.7	-0.8	4Fe-4S binding protein
MMP_RS01830		-2.7	-2.2	tRNA-Val
MMP_RS06400		-2.6	-2.1	4Fe-4S binding protein
MMP_RS05515		-2.6	-7.0	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS02240		-2.5	-5.1	methanogenesis marker 7 protein
MMP_RS04780		-2.5	-3.9	ribonuclease P
MMP_RS06355		-2.5	-2.9	molybdenum cofactor biosynthesis protein MoaE
MMP_RS07735		-2.5	-1.1	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS01020		-2.5	-1.2	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03015		-2.5	-13.3	GTP 3' 8-cyclase MoaA
MMP_RS08300		-2.4	-1.2	metal-sulfur cluster assembly factor
MMP_RS04605		-2.3	-4.0	cobalt ECF transporter T component CbiQ
MMP_RS06350		-2.3	-9.4	HesA/MoeB/ThiF family protein
MMP_RS02195		-2.3	-4.5	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS07635		-2.3	-9.0	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01960		-2.3	-0.8	hypothetical protein
MMP_RS03400		-2.3	-3.4	archease
MMP_RS06625		-2.3	-2.6	DNA primase
MMP_RS01175		-2.3	-4.7	triphosphoribosyl-dephospho-CoA synthase
MMP_RS07545		-2.2	-1.2	HTH domain-containing protein
MMP_RS08745		-2.2	-7.2	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS01545		-2.2	-1.3	CBS domain-containing protein
MMP_RS03035		-2.2	-4.2	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06315		-2.2	-1.1	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS06230		-2.1	-3.0	helix-turn-helix domain-containing protein
MMP_RS08790		-2.1	-2.5	translation initiation factor IF-2 subunit alpha
MMP_RS01265		-2.1	-4.1	hypothetical protein
MMP_RS04620		-2.1	-13.2	cobalt transporter CbiM
MMP_RS06730		-2.1	-2.5	phosphopantothenate/pantothenate synthetase
MMP_RS01610		-2.1	-3.8	hypothetical protein
MMP_RS06270		-2.0	-7.0	TIGR00300 family protein
MMP_RS01005		-2.0	-1.3	riboflavin synthase
MMP_RS07845		-2.0	-3.3	LL-diaminopimelate aminotransferase
MMP_RS01500		-2.0	-2.6	CBS domain-containing protein
MMP_RS02135		-2.0	-4.9	DUF5612 domain-containing protein
MMP_RS06120		-2.0	-2.3	UPF0147 family protein
MMP_RS09020		-2.0	-1.8	hypothetical protein
MMP_RS07750		-1.9	-4.8	DUF357 domain-containing protein
MMP_RS02280		-1.9	-1.0	DUF211 domain-containing protein
MMP_RS02355		-1.9	-3.4	30S ribosomal protein S27ae
MMP_RS03025		-1.9	-5.9	molybdenum cofactor guanylyltransferase
MMP_RS07755		-1.9	-1.3	DUF555 domain-containing protein
MMP_RS04775		-1.9	-4.0	adenosylhomocysteinase
MMP_RS01225		-1.9	-6.7	DUF5379 domain-containing protein
MMP_RS06295		-1.9	-6.9	methanogenesis marker 14 protein
MMP_RS04685		-1.9	-2.2	DUF126 domain-containing protein
MMP_RS02800		-1.8	-7.1	nucleotidyltransferase domain-containing protein
MMP_RS07730		-1.8	-2.0	pyruvate synthase subunit beta
MMP_RS01220		-1.8	-8.3	hypothetical protein
MMP_RS02900		-1.8	-0.7	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS05550		-1.8	-0.7	cation:proton antiporter
MMP_RS03600		-1.8	-2.6	triose-phosphate isomerase
MMP_RS03700		-1.8	-9.0	sodium:proton antiporter
MMP_RS04615		-1.8	-4.4	PDGLE domain-containing protein
MMP_RS08650		-1.8	-3.1	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS07630		-1.8	-1.5	ATP-binding cassette domain-containing protein
MMP_RS04890		-1.8	-0.9	adenylyltransferase/cytidyltransferase family protein
MMP_RS00685		-1.7	-4.8	2-phospho-L-lactate guanylyltransferase
MMP_RS02875		-1.7	-6.7	chorismate pyruvate-lyase family protein
MMP_RS01700		-1.7	-1.1	dihydroxy-acid dehydratase
MMP_RS05845		-1.7	-1.8	tRNA-intron lyase
MMP_RS06925		-1.7	-2.1	ribonuclease VapC4
MMP_RS07575		-1.7	-3.3	RNA ligase partner protein
MMP_RS01795		-1.6	-1.7	methanogenesis marker 6 protein
MMP_RS06895		-1.6	-1.6	selenocysteine-specific translation elongation factor
MMP_RS06215		-1.6	-2.9	30S ribosomal protein S6e
MMP_RS06340		-1.6	-8.4	phosphoadenosine phosphosulfate reductase family protein
MMP_RS04500		-1.6	-12.8	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS01890		-1.5	-4.0	nucleotide sugar dehydrogenase
MMP_RS04720		-1.5	-2.5	DedA family protein
MMP_RS08635		-1.5	-1.8	UbiA family prenyltransferase
MMP_RS06475		-1.5	-3.7	FAD-dependent oxidoreductase
MMP_RS00520		-1.5	-1.4	RNA polymerase Rpb4 family protein
MMP_RS02010		-1.5	-5.9	PHP domain-containing protein
MMP_RS00300		-1.5	-0.6	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS07600		-1.5	-2.7	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS08715		-1.4	-1.8	formylmethanofuran dehydrogenase subunit B
MMP_RS08105		-1.4	-5.6	6-carboxyhexanoate--CoA ligase
MMP_RS05250		-1.4	-1.2	NFYB/HAP3 family transcription factor subunit
MMP_RS05540		-1.4	-3.0	hypothetical protein
MMP_RS08720		-1.4	-1.4	4Fe-4S binding protein
MMP_RS06395		-1.4	-2.7	ThiF family adenylyltransferase
MMP_RS08460		-1.4	-2.1	proteasome-activating nucleotidase
MMP_RS03155		-1.4	-6.4	precorrin-6A reductase
MMP_RS06725		-1.4	-7.8	hypothetical protein
MMP_RS00985		-1.4	-4.7	CDC48 family AAA ATPase
MMP_RS03445		-1.4	-0.9	methanogenesis marker 17 protein
MMP_RS06370		-1.4	-4.0	biotin synthase BioB
MMP_RS01380		-1.4	-4.7	PHP domain-containing protein
MMP_RS08820		-1.3	-5.3	hypothetical protein
MMP_RS00110		-1.3	-2.7	hypothetical protein
MMP_RS04585		-1.3	-7.3	AIR synthase related protein
MMP_RS06130		-1.3	-2.6	peptidylprolyl isomerase
MMP_RS06105		-1.3	-6.1	hydrogenase maturation peptidase HycI
MMP_RS08435		-1.3	-1.6	Era-like GTP-binding protein
MMP_RS07200		-1.3	-5.4	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS01800		-1.3	-3.0	TIGR00303 family protein
MMP_RS06885		-1.3	-2.4	50S ribosome-binding GTPase
MMP_RS06630		-1.3	-1.0	UPF0058 family protein
MMP_RS08440		-1.3	-2.1	cell division protein SepF
MMP_RS01905		-1.3	-7.8	glycosyltransferase
MMP_RS00810		-1.3	-6.4	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS06020		-1.3	-3.6	archaeoflavoprotein AfpA
MMP_RS02145		-1.3	-6.7	winged helix-turn-helix transcriptional regulator
MMP_RS07645		-1.3	-4.9	aldehyde dehydrogenase family protein
MMP_RS03140		-1.3	-8.9	hypothetical protein
MMP_RS01900		-1.3	-7.8	hypothetical protein
MMP_RS00515		-1.3	-0.8	DUF655 domain-containing protein
MMP_RS01755		-1.3	-1.0	DUF2097 domain-containing protein
MMP_RS07425		-1.3	-5.2	GTP-binding protein
MMP_RS01325		-1.3	-1.6	dihydroneopterin aldolase family protein
MMP_RS07625		-1.3	-2.7	cobalt ECF transporter T component CbiQ
MMP_RS05425		-1.3	-3.9	monovalent cation/H+ antiporter complex subunit F
MMP_RS08095		-1.2	-6.8	dethiobiotin synthase
MMP_RS05265		-1.2	-2.3	2-isopropylmalate synthase
MMP_RS07710		-1.2	-7.2	cell division protein FtsZ
MMP_RS00675		-1.2	-0.9	nitroreductase family protein
MMP_RS06940		-1.2	-2.7	polyprenyl diphosphate synthase
MMP_RS01725		-1.2	-3.0	class I SAM-dependent methyltransferase family protein
MMP_RS08350		-1.2	-0.9	hypothetical protein
MMP_RS04955		-1.2	-5.9	DNA topoisomerase I
MMP_RS06855		-1.2	-6.0	hypothetical protein
MMP_RS03435		-1.2	-1.6	ketol-acid reductoisomerase
MMP_RS07355		-1.2	-0.9	transcription factor S
MMP_RS00695		-1.2	-0.8	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS05555		-1.2	-1.1	DUF4040 domain-containing protein
MMP_RS02235		-1.2	-4.7	CBS domain-containing protein
MMP_RS03640		-1.2	-3.2	archaeal proteasome endopeptidase complex subunit beta
MMP_RS07580		-1.1	-2.5	DUF356 domain-containing protein
MMP_RS00115		-1.1	-7.4	radical SAM protein
MMP_RS08210		-1.1	-1.6	phosphatidylglycerophosphatase A
MMP_RS05580		-1.1	-8.5	glycosyltransferase
MMP_RS01925		-1.1	-3.8	DUF1616 domain-containing protein
MMP_RS06670		-1.1	-3.5	glucose-6-phosphate isomerase
MMP_RS01955		-1.1	-2.1	hypothetical protein
MMP_RS08100		-1.1	-4.3	8-amino-7-oxononanoate synthase
MMP_RS07875		-1.1	-4.3	hypothetical protein
MMP_RS06865		-1.1	-1.8	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS09025		-1.1	-0.9	hypothetical protein
MMP_RS05430		-1.1	-2.9	TIGR00288 family NYN domain-containing protein
MMP_RS05920		-1.1	-0.5	50S ribosomal protein L37e
MMP_RS06110		-1.1	-3.0	ATP-dependent protease LonB
MMP_RS02165		-1.1	-3.6	tRNA-dihydrouridine synthase
MMP_RS05545		-1.0	-3.1	pyridoxal phosphate-dependent aminotransferase
MMP_RS02885		-1.0	-8.3	molybdopterin biosynthesis protein
MMP_RS00130		-1.0	-1.0	nickel-responsive transcriptional regulator NikR
MMP_RS07350		-1.0	-1.0	preprotein translocase subunit Sec61beta
MMP_RS06685		-1.0	-6.2	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS07195		-1.0	-6.1	M20 family metallo-hydrolase
MMP_RS03250		-1.0	-2.6	MJ1244 family protein
MMP_RS00320		-1.0	-1.2	class I SAM-dependent methyltransferase
MMP_RS00305		-1.0	-1.1	phosphoribosyl-ATP diphosphatase
MMP_RS05925		-1.0	-2.5	small nuclear ribonucleoprotein
MMP_RS07435		-1.0	-1.7	GMP synthase subunit A
MMP_RS03385		-1.0	-0.8	cation diffusion facilitator family transporter
MMP_RS05815		-1.0	-1.7	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06840		-1.0	-0.7	DNA-directed RNA polymerase subunit N
MMP_RS08840		-1.0	-6.0	class I SAM-dependent methyltransferase
MMP_RS01880		-1.0	-4.5	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS00725		-1.0	-4.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS02100		-1.0	-2.9	metallophosphoesterase
MMP_RS07540		-1.0	-2.9	CBS domain-containing protein
MMP_RS04850		-1.0	-7.1	UPF0254 family protein
MMP_RS07695		-1.0	-3.0	DUF3236 domain-containing protein
MMP_RS07620		-0.9	-2.7	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS05640		-0.9	-4.4	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS08645		-0.9	-3.8	UPF0179 family protein
MMP_RS05345		-0.9	-3.6	hypothetical protein
MMP_RS01665		-0.9	-2.4	DUF2111 domain-containing protein
MMP_RS03145		-0.9	-5.0	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS03095		-0.9	-3.2	diphthine synthase
MMP_RS01910		-0.9	-4.6	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS00450		-0.9	-1.5	4Fe-4S binding protein
MMP_RS07525		-0.9	-3.9	4Fe-4S binding protein
MMP_RS00050		-0.9	-3.0	AarF/UbiB family protein
MMP_RS01885		-0.9	-3.3	Gfo/Idh/MocA family oxidoreductase
MMP_RS02110		-0.9	-1.4	hypothetical protein
MMP_RS01335		-0.9	-1.7	prefoldin subunit beta
MMP_RS07615		-0.9	-3.3	energy-coupling factor ABC transporter permease
MMP_RS01365		-0.8	-2.0	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS01045		-0.8	-3.5	diphthamide biosynthesis enzyme Dph2
MMP_RS03440		-0.8	-0.8	MoaD/ThiS family protein
MMP_RS01875		-0.8	-3.6	N-acetyltransferase
MMP_RS08445		-0.8	-2.5	DUF2099 family protein
MMP_RS05525		-0.8	-3.7	calcium/sodium antiporter
MMP_RS06900		-0.8	-2.2	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06680		-0.8	-3.3	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01385		-0.8	-0.4	imidazole glycerol phosphate synthase subunit HisH
MMP_RS06980		-0.8	-3.2	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS00735		-0.8	-2.7	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS00315		-0.8	-3.1	Nif3-like dinuclear metal center hexameric protein
MMP_RS01865		-0.8	-1.0	GPR1/FUN34/YaaH family transporter
MMP_RS06600		-0.8	-1.0	class III signal peptide-containing protein
MMP_RS08330		-0.8	-3.7	NADH-quinone oxidoreductase subunit H
MMP_RS05635		-0.8	-4.8	NAD-dependent epimerase/dehydratase family protein
MMP_RS05765		-0.8	-2.4	M42 family metallopeptidase
MMP_RS06485		-0.8	-0.7	zinc ribbon domain-containing protein
MMP_RS00895		-0.8	-1.5	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in rich t1 experiments